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  1. Article ; Conference proceedings: Fagomine occurrence in African honey

    Katerere, David / Penkova, Yana B. / Nash, Robert J

    Planta Medica

    2023  Volume 89, Issue 14

    Event/congress 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Trinity College Dublin Ireland, 2023-07-02
    Language English
    Publishing date 2023-11-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 123545-x
    ISSN 1439-0221 ; 0032-0943
    ISSN (online) 1439-0221
    ISSN 0032-0943
    DOI 10.1055/s-0043-1774051
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Uf I Zs.157: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Iminosugar Amino Acid idoBR1 Reduces Inflammatory Responses in Microglia.

    Olajide, Olumayokun A / Iwuanyanwu, Victoria U / Banjo, Owolabi W / Kato, Atsushi / Penkova, Yana B / Fleet, George W J / Nash, Robert J

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 10

    Abstract: 1) Background. Inflammation is reported to be a key factor in neurodegeneration. The microglia are immune cells present in the central nervous system; their activation results in the release of inflammatory cytokines and is thought to be related to ... ...

    Abstract (1) Background. Inflammation is reported to be a key factor in neurodegeneration. The microglia are immune cells present in the central nervous system; their activation results in the release of inflammatory cytokines and is thought to be related to aging and neurodegenerative disorders, such as Alzheimer's disease. (2) Methods. A mouse BV-2 microglia cell line was activated using LPS and the anti-inflammatory cucumber-derived iminosugar amino acid idoBR1, (2
    MeSH term(s) Amino Acids/metabolism ; Animals ; Anti-Inflammatory Agents/metabolism ; Anti-Inflammatory Agents/pharmacology ; Lipopolysaccharides ; Mice ; Microglia ; Nitric Oxide Synthase Type II/metabolism
    Chemical Substances Amino Acids ; Anti-Inflammatory Agents ; Lipopolysaccharides ; Nitric Oxide Synthase Type II (EC 1.14.13.39)
    Language English
    Publishing date 2022-05-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27103342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  3. Article ; Online: Synthesis of (

    Al-Taie, Zahraa S / Bartholomew, Barbara / Cartmell, Christopher / Froom, Richard T / Kerr, Russell G / Kraehenbuehl, Rolf / Murphy, Patrick J / Nash, Robert J / Penkova, Yana B / van Teijlingen, Alexander

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 4

    Abstract: The absolute stereochemistry of the marine alkaloid ( ...

    Abstract The absolute stereochemistry of the marine alkaloid (
    MeSH term(s) Alkaloids/chemical synthesis ; Alkaloids/chemistry ; Chemistry Techniques, Synthetic ; Combinatorial Chemistry Techniques ; Molecular Structure
    Chemical Substances Alkaloids
    Language English
    Publishing date 2022-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27041338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  4. Article: Cyclic guanidine containing amino acids that promote glucocerebrosidase

    Al-Taie, Zahraa S. / Bartholomew, Barbara / Coles, Simon J. / Evans, Daniel M. / Hollinshead, Jackie / Jones, Leigh F. / Kraehenbuehl, Rolf / Murphy, Patrick J. / Nash, Robert J. / Penkova, Yana B. / Tizzard, Graham J.

    Tetrahedron. 2022 July 28,

    2022  

    Abstract: Novel cyclic guanidine containing amino acids (S)-1, 2 and 3 were prepared from l-serine 5. (S)-2-Imino-3-methylimidazolidine-4-carboxylic acid hydrochloride salt 2. HCl and (3S, 6S)-3,6-bis(hydroxymethyl)-1,4-dimethylpiperazine-2,5-dione 15 showed in ... ...

    Abstract Novel cyclic guanidine containing amino acids (S)-1, 2 and 3 were prepared from l-serine 5. (S)-2-Imino-3-methylimidazolidine-4-carboxylic acid hydrochloride salt 2. HCl and (3S, 6S)-3,6-bis(hydroxymethyl)-1,4-dimethylpiperazine-2,5-dione 15 showed in vitro promotion of the enzyme glucocerebrosidase.
    Keywords glucosylceramidase ; guanidines ; serine
    Language English
    Dates of publication 2022-0728
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 204285-x
    ISSN 1464-5416 ; 0040-4020 ; 0563-2064
    ISSN (online) 1464-5416
    ISSN 0040-4020 ; 0563-2064
    DOI 10.1016/j.tet.2022.132959
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1076: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Iminosugar idoBR1 Isolated from Cucumber

    Nash, Robert J / Bartholomew, Barbara / Penkova, Yana B / Rotondo, Dino / Yamasaka, Fernanda / Stafford, Graham P / Jenkinson, Sarah F / Fleet, George W J

    ACS omega

    2020  Volume 5, Issue 26, Page(s) 16263–16271

    Abstract: Cucumbers have been anecdotally claimed to have anti-inflammatory activity for a long time, but the active principle was not identified. idoBR1, ( ... ...

    Abstract Cucumbers have been anecdotally claimed to have anti-inflammatory activity for a long time, but the active principle was not identified. idoBR1, (2
    Language English
    Publishing date 2020-06-23
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.0c02092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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