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  1. Book ; Conference proceedings: Proceedings of the 2010 Heart Brain Summit

    Penn, Marc S.

    September 23 - 24, 2010 [Las Vegas, Nevada]

    (Cleveland Clinic journal of medicine ; 78, Suppl. 1)

    2011  

    Title variant Proceedings of the 2010 Heart-Brain Summit
    Event/congress Heart Brain Summit (2010, LasVegasNev.)
    Author's details suppl. ed. Marc S. Penn
    Series title Cleveland Clinic journal of medicine ; 78, Suppl. 1
    Collection
    Language English
    Size S103 S. : graph. Darst.
    Publisher Cleveland Clinic Foundation
    Publishing place Cleveland, OH
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT017035079
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Conference proceedings: Proceedings of the 2009 Heart Brain Summit

    Penn, Marc S.

    at Cleveland Clinic ... October 15 - 16, 2009

    (Cleveland Clinic journal of medicine ; 77, Suppl. 3)

    2010  

    Title variant Proceedings of the 2009 Heart-Brain Summit
    Event/congress Heart Brain Summit (4, 2009, ClevelandOhio)
    Author's details suppl. ed. Marc S. Penn
    Series title Cleveland Clinic journal of medicine ; 77, Suppl. 3
    Collection
    Language English
    Size S91 S. : Ill., graph. Darst.
    Publisher Cleveland Clinic Foundation
    Publishing place Cleveland, OH
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT016510535
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Conference proceedings: Proceedings of the 3rd Heart Brain Summit

    Penn, Marc S.

    June 4 - 5, 2008, hosted by the Earl and Doris Bakken Heart-Brain Institute at Cleveland Clinic

    (Cleveland Clinic journal of medicine ; 76, Suppl. 2)

    2009  

    Title variant Proceedings of the 3rd Heart-Brain Summit
    Event/congress Heart Brain Summit (3, 2008, ClevelandOhio)
    Author's details suppl. ed. Marc S. Penn
    Series title Cleveland Clinic journal of medicine ; 76, Suppl. 2
    Collection
    Language English
    Size S99 S. : Ill., graph. Darst.
    Publisher Cleveland Clinic Foundation
    Publishing place Cleveland, OH
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT015968147
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Conference proceedings: Proceedings of the 2nd Heart Brain Summit

    Penn, Marc S.

    June 7 - 8, 2007, hosted by the Earl and Doris Bakken Heart-Brain Institute at Cleveland Clinic

    (Cleveland Clinic journal of medicine ; 75, Suppl. 2)

    2008  

    Title variant Proceedings of the 2nd Heart-Brain Summit
    Event/congress Heart Brain Summit (2, 2007, ClevelandOhio)
    Author's details suppl. ed. Marc S. Penn
    Series title Cleveland Clinic journal of medicine ; 75, Suppl. 2
    Collection
    Language English
    Size S110 S. : Ill., graph. Darst.
    Publisher Cleveland Clinic Foundation
    Publishing place Cleveland, OH
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT015536837
    Database Catalogue ZB MED Medicine, Health

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  5. Book ; Online: Stem Cells And Myocardial Regeneration

    Penn, Marc S.

    2007  

    Author's details edited by Marc S. Penn
    Keywords Cardiology
    Language English
    Publisher Humana Press Inc
    Publishing place Totowa, NJ
    Document type Book ; Online
    HBZ-ID TT050387135
    ISBN 978-1-588-29664-1 ; 978-1-597-45272-4 ; 1-588-29664-4 ; 1-597-45272-6
    DOI 10.1007/978-1-59745-272-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book: Stem cells and myocardial regeneration

    Penn, Marc S.

    (Contemporary cardiology)

    2007  

    Author's details ed. by Marc S. Penn
    Series title Contemporary cardiology
    Keywords Myocardium / cytology ; Stem Cells / physiology ; Regeneration / physiology
    Language English
    Size XIII, 315 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, N.J
    Publishing country United States
    Document type Book
    HBZ-ID HT014731313
    ISBN 1-58829-664-4 ; 978-1-58829-664-1
    Database Catalogue ZB MED Medicine, Health

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  7. Book ; Conference proceedings: Proceedings of the Heart Brain Summit

    Penn, Marc S.

    June 15 - 17, 2006 ... at Cleveland Clinic

    (Cleveland Clinic journal of medicine ; 74, Suppl. 1)

    2007  

    Event/congress Heart Brain Summit (2006, ClevelandOhio)
    Author's details suppl. ed. Marc S. Penn
    Series title Cleveland Clinic journal of medicine ; 74, Suppl. 1
    Collection
    Language English
    Size S141 S. : Ill., graph. Darst.
    Publisher Cleveland Clinic Foundation
    Publishing place Cleveland, OH
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT015043335
    Database Catalogue ZB MED Medicine, Health

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  8. Article ; Online: The Unraveling of the Matryoshka Doll.

    Penn, Marc S

    Circulation research

    2017  Volume 120, Issue 7, Page(s) 1075–1077

    MeSH term(s) Adult ; Adult Stem Cells/metabolism ; Adult Stem Cells/transplantation ; Exosomes/genetics ; Exosomes/metabolism ; Gene Expression ; Heart Diseases/physiopathology ; Heart Diseases/therapy ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Regenerative Medicine/methods ; Regenerative Medicine/trends ; Stem Cell Transplantation/methods
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2017-03-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.116.309904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The importance of understanding the molecular mechanism of stem cell-induced cardiac tissue repair.

    Penn, Marc S

    Regenerative medicine

    2013  Volume 8, Issue 4, Page(s) 381–384

    MeSH term(s) Humans ; Myocytes, Cardiac/cytology ; Regenerative Medicine ; Stem Cells/cytology ; Tissue Engineering
    Language English
    Publishing date 2013-07
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274500-2
    ISSN 1746-076X ; 1746-0751
    ISSN (online) 1746-076X
    ISSN 1746-0751
    DOI 10.2217/rme.13.38
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Association of chronic neutrophil activation with risk of mortality.

    Penn, Marc S / MacRae, Calum / Goldfaden, Rebecca F / Choksi, Rushab R / Smith, Steven / Wrenn, David / Saghir, Mouris X / Klemes, Andrea B

    PloS one

    2023  Volume 18, Issue 7, Page(s) e0288712

    Abstract: Background: Levels of free myeloperoxidase (MPO), a cardiovascular risk marker, have been reported to decline with standard care. Whether such declines signify decreased risk of mortality remains unknown.: Design: Cox proportional hazard models were ... ...

    Abstract Background: Levels of free myeloperoxidase (MPO), a cardiovascular risk marker, have been reported to decline with standard care. Whether such declines signify decreased risk of mortality remains unknown.
    Design: Cox proportional hazard models were generated using data from a retrospective cohort study of prospectively collected measures.
    Participants: Patients (3,658) who had MPO measurements and LDL-C ≥ 90 mg/dL during 2011-2015 were selected based on a stratified random sampling on MPO risk level. Baseline MPO was either low (<470 pmol/L), moderate (470-539 pmol/L), or high (≥540 pmol/L).
    Main outcomes and measures: First occurrence of MACE (myocardial infarction, stroke, coronary revascularization, or all-cause death).
    Results: Mean age was 66.5 years, and 64.7% were women. During a mean 6.5-year follow-up, crude incidence per 1000 patient years was driven by death. The incidence and all-cause death was highest for patients with high MPO (21.2; 95% CI, 19.0-23.7), then moderate (14.6; 95% CI, 11.5-18.5) and low (2.3; 95% CI, 1.2-4.6) MPO. After adjusting for age, sex, and cardiovascular risk factors, risk of cardiovascular death did not differ significantly between patients with high and low MPO (HR, 1.57; 95% CI, 0.56-4.39), but patients with high MPO had greater risk of non-cardiovascular (HR, 6.15; 95% CI, 2.27-16.64) and all-cause (HR, 3.83; 95% CI, 1.88-7.78) death. During follow-up, a 100 pmol/L decrease in MPO correlated with a 5% reduction in mortality (HR, 0.95; 95% CI, 0.93-0.97) over 5 years.
    Conclusions: Free circulating MPO is a strong marker of risk of mortality. Monitoring changes in MPO levels over time may provide insight into changes in physiology that mark a patient for increased risk of mortality.
    MeSH term(s) Humans ; Female ; Aged ; Male ; Retrospective Studies ; Neutrophil Activation ; Myocardial Infarction ; Stroke ; Risk Factors ; Cardiovascular Diseases
    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0288712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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