Article ; Online: Prognostic evaluation of
2022 Volume 30, Issue 4, Page(s) 570–576
Abstract: Background: Since the emergence of the pandemic of SARS-CoV-2, a high reported incidence of VAP in COVID-19 sustained by carbapenem resistant : Materials and methods: We retrospectively collected COVID-19 patients who developed CRAB-VAP - defined ... ...
Abstract | Background: Since the emergence of the pandemic of SARS-CoV-2, a high reported incidence of VAP in COVID-19 sustained by carbapenem resistant Materials and methods: We retrospectively collected COVID-19 patients who developed CRAB-VAP - defined according to Center for Diseases Control (CDC) 2020 criteria and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) or Infectious Diseases Society of America (IDSA) guidelines - to describe characteristics and outcome. Results: Among 21 patients with CRAB-VAP in COVID-19, median age was 66 years (IQR 41-80). Median time of VAP-onset was 7 days (IQR 0-28 days) from ICU - admission and 76.2% had septic shock. Treatment regimens were all colistin-based, in 28% (n=6) including ampicillin/sulbactam and rifampicin. In three cases, cefiderocol was started as rescue. Survival rate at 28-days was 35% (n=7). Conclusion: Non-fermenting Gram-negative bacteria are an emerging aetiology of VAP in COVID-19 patients. This underscores the urgent need for proper microbiological identification to address therapies and infection control protocols. |
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Language | English |
Publishing date | 2022-12-01 |
Publishing country | Italy |
Document type | Journal Article |
ZDB-ID | 2041081-5 |
ISSN | 2532-8689 ; 1124-9390 |
ISSN (online) | 2532-8689 |
ISSN | 1124-9390 |
DOI | 10.53854/liim-3004-12 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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