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  1. Article ; Online: Prognostic evaluation of

    De Benedetto, Ilaria / Lupia, Tommaso / Shbaklo, Nour / Bianchi, Alessandro / Concialdi, Erika / Penna, Maurizio / Corcione, Silvia / De Rosa, Francesco Giuseppe

    Le infezioni in medicina

    2022  Volume 30, Issue 4, Page(s) 570–576

    Abstract: Background: Since the emergence of the pandemic of SARS-CoV-2, a high reported incidence of VAP in COVID-19 sustained by carbapenem resistant : Materials and methods: We retrospectively collected COVID-19 patients who developed CRAB-VAP - defined ... ...

    Abstract Background: Since the emergence of the pandemic of SARS-CoV-2, a high reported incidence of VAP in COVID-19 sustained by carbapenem resistant
    Materials and methods: We retrospectively collected COVID-19 patients who developed CRAB-VAP - defined according to Center for Diseases Control (CDC) 2020 criteria and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) or Infectious Diseases Society of America (IDSA) guidelines - to describe characteristics and outcome.
    Results: Among 21 patients with CRAB-VAP in COVID-19, median age was 66 years (IQR 41-80). Median time of VAP-onset was 7 days (IQR 0-28 days) from ICU - admission and 76.2% had septic shock. Treatment regimens were all colistin-based, in 28% (n=6) including ampicillin/sulbactam and rifampicin. In three cases, cefiderocol was started as rescue. Survival rate at 28-days was 35% (n=7).
    Conclusion: Non-fermenting Gram-negative bacteria are an emerging aetiology of VAP in COVID-19 patients. This underscores the urgent need for proper microbiological identification to address therapies and infection control protocols.
    Language English
    Publishing date 2022-12-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3004-12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Legionella pneumophila

    Lupia, Tommaso / Corcione, Silvia / Shbaklo, Nour / Rizzello, Barbara / De Benedetto, Ilaria / Concialdi, Erika / Navazio, Anna Sara / Penna, Maurizio / Brusa, Maria Teresa / De Rosa, Francesco Giuseppe

    Microorganisms

    2023  Volume 11, Issue 2

    Abstract: Legionella ... ...

    Abstract Legionella pneumophila
    Language English
    Publishing date 2023-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11020498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Autochthonous West Nile Virus Infection Outbreak in Humans (Asti, Piedmont, Italy, August-October 2018) and Long-Term Sequelae Follow-Up.

    Lupia, Tommaso / Libanore, Valentina / Corcione, Silvia / Fornari, Valentina / Rizzello, Barbara / Bosio, Roberta / Stroffolini, Giacomo / Bigliano, Paolo / Fontana, Silvia / Patti, Francesca / Brusa, Maria Teresa / Degioanni, Maria / Concialdi, Erika / Navazio, Anna Sara / Penna, Maurizio / De Rosa, Francesco Giuseppe

    Tropical medicine and infectious disease

    2022  Volume 7, Issue 8

    Abstract: West Nile virus (WNV) infection is a reemerging zoonosis recently provoking significant outbreaks throughout Europe. During the summer of 2018, the number of WNV infections rose with a peak of new diagnoses of West Nile neuro-invasive disease (WNND). ... ...

    Abstract West Nile virus (WNV) infection is a reemerging zoonosis recently provoking significant outbreaks throughout Europe. During the summer of 2018, the number of WNV infections rose with a peak of new diagnoses of West Nile neuro-invasive disease (WNND). Most of the Italian cases were clustered in the Po River Valley. We present a case series of nine patients with WNV infection admitted to the Cardinal Massaia Hospital from 30 August 2018 to 1 October 2018. Demographic, immunovirological, clinical and therapeutic data are shown, and a report on clinical sequelae from the subsequent follow-up in patients with WNV and WNND. We showed the clinical, radiological and biochemical characteristics of WNV-infected patients. The risk factors and the clinical presentation of WNV in most patients in our case series were typical of that described in the literature, although, despite the high morbidity and mortality of WNND, we showed survival of 100% and long-term sequelae in only three patients. Environmental conditions may be essential in WNV outbreaks, and WNND can be clinically neurological multiform. Our long-lasting follow-up with clinical or radiological monitoring confirmed the morbidity of long-term neurological sequelae after WNND. Further studies are needed to investigate the epidemiology and physiopathology of bacterial superinfections after WNV infection.
    Language English
    Publishing date 2022-08-16
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed7080185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Synthesis of (R)-N-Tosylemeriamine via Chiral N-Tosylimidazolidin-2-ones

    Cardillo, Giuliana / Orena, Mario / Penna, Maurizio / Sandri, Sergio / Tomasini, Claudia

    Synlett

    1990  Volume 1990, Issue 09, Page(s) 543–544

    Language English
    Publishing date 1990-01-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2042012-2
    ISSN 1437-2096 ; 0936-5214
    ISSN (online) 1437-2096
    ISSN 0936-5214
    DOI 10.1055/s-1990-21160
    Database Thieme publisher's database

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