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  1. Article: Serie: Psychische stoornissen in de mondzorgpraktijk. ADHD bij kinderen en volwassenen.

    Rodrigues Pereira, R

    Nederlands tijdschrift voor tandheelkunde

    2021  Volume 128, Issue 3, Page(s) 150–153

    Abstract: ADHD is common in children as well as in adults. Dental problems are more common in these individuals as they can often be forgetful and impulsive. They are less careful with their teeth and are more at risk of damage. Medication can also have side ... ...

    Title translation Series: Mental disorders in a dental practice. ADHD in children and adults.
    Abstract ADHD is common in children as well as in adults. Dental problems are more common in these individuals as they can often be forgetful and impulsive. They are less careful with their teeth and are more at risk of damage. Medication can also have side effects such as a dry mouth which is not conducive to the teeth. A number of advice are given for easier and better dental care. Timing and dosage of medication is of great importance here. Dentists can have ADHD as well, which can be a handicap in their practice.
    MeSH term(s) Adult ; Attention Deficit Disorder with Hyperactivity/diagnosis ; Child ; Humans ; Tooth ; Xerostomia
    Language Dutch
    Publishing date 2021-03-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 603498-6
    ISSN 0028-2200
    ISSN 0028-2200
    DOI 10.5177/ntvt.2021.03.20099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The sterile insect technique: an international framework to facilitate transboundary shipments of sterile insects.

    Enkerlin, W R / Pereira, R

    Revue scientifique et technique (International Office of Epizootics)

    2022  Volume 41, Issue 1, Page(s) 66–74

    Abstract: The sterile insect technique (SIT) has been successfully used since the 1950s as part of an integrated pest management approach in large-scale programmes to prevent, contain, suppress and eradicate key insect pests in many countries throughout the world. ...

    Title translation The sterile insect technique: an international framework to facilitate transboundary shipments of sterile insects.
    Abstract The sterile insect technique (SIT) has been successfully used since the 1950s as part of an integrated pest management approach in large-scale programmes to prevent, contain, suppress and eradicate key insect pests in many countries throughout the world. During this period, over one trillion live sterile insects have been shipped across borders. The very few adverse incidents from this significant trade were managed and resulted in no significant impacts. The phytosanitary and zoosanitary requirements by importing countries have been simple, facilitating the transboundary shipment of sterile insects, which is carried out mostly under the framework of cooperative agreements between the governments of the countries involved, and under technical cooperation projects of the United Nations. However, the shipment of sterile insects from sources outside this governmental framework, including public-private facilities, has been complicated, despite the availability of harmonised international guidelines in some cases, such as those for fruit flies. The SIT has great potential for the control of endemic pests or against the growing threat of invasive pests that can affect whole regions and even continents. Since SIT is species-specific, with negligible risk of introducing unwanted invasive species to the environment, and with the advantage of reducing insecticide use, a harmonised framework that recognises the low risk of SIT would facilitate shipments of sterile insects across borders and help to expand the use of this effective and environmentally friendly technology. The scope of this paper is limited to insects that have been sterilised using ionising radiation.
    MeSH term(s) Animals ; Insecta ; Pest Control, Biological/methods
    Language English
    Publishing date 2022-07-26
    Publishing country France
    Document type Journal Article
    ZDB-ID 792125-1
    ISSN 1608-0637 ; 0253-1933
    ISSN (online) 1608-0637
    ISSN 0253-1933
    DOI 10.20506/rst.41.1.3303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Guidelines-based therapeutic strategies for controlling hypertension in non-controlled hypertensive patients followed by family physicians in primary health care in Portugal: the GPHT-PT study.

    Polónia, Jorge / Marques Pereira, Raul

    Blood pressure

    2024  Volume 33, Issue 1, Page(s) 2345887

    Abstract: Purpose: In a prospective open study, with intervention, conducted in Primary Health Care Units by General Practitioners (GPs) in Portugal, the effectiveness of a single pill of candesartan/amlodipine (ARB/amlodipine), as the only anti-hypertension ( ... ...

    Abstract Purpose: In a prospective open study, with intervention, conducted in Primary Health Care Units by General Practitioners (GPs) in Portugal, the effectiveness of a single pill of candesartan/amlodipine (ARB/amlodipine), as the only anti-hypertension (anti-HTN) medication, in adult patients with uncontrolled HTN (BP > 140/or > 90 mm Hg), either previously being treated with anti-HTN monotherapies (Group I), or combinations with hydrochlorothiazide (HCTZ) (Group II), or not receiving medication at all (Group III), was evaluated across 12-weeks after implementation of the new therapeutic measure.
    Materials and methods: A total of 118 GPs recruited patients with uncontrolled HTN who met inclusion/exclusion criteria. Participants were assigned, according to severity, one of 3 (morning) fixed combination candesartan/amlodipine dosage (8/5 or 16/5 or 16/10 mg/day) and longitudinally evaluated in 3 visits (v0, v6 and v12 weeks). Office blood pressure was measured in each visit, and control of HTN was defined per guidelines (BP< 140/90 mmHg).
    Results: Of the 1234 patients approached, 752 (age 61 ± 10 years, 52% women) participated in the study and were assigned to groups according to previous treatment conditions. The 3 groups exhibited a statistically significant increased control of blood pressure after receiving the fixed combination candesartan/amlodipine dosage. The overall proportion of controlled HTN participants increased from 0,8% at v0 to 82% at v12. The mean arterial blood pressure values decreased from SBP= 159.0 (± 13.0) and DBP= 91.1 (± 9.6) at baseline to SBP= 132,1 (± 11.3) and DBP= 77,5 (± 8.8) at 12 weeks (
    Conclusion: In patients with uncontrolled HTN, therapeutic measures in accordance with guidelines, with a fixed combination candesartan/amlodipine, allowed to overall achieve HTN control at 12 weeks in 82% of previously uncontrolled HTN patients, reinforcing the advantages of these strategies in primary clinical practice.
    MeSH term(s) Humans ; Hypertension/drug therapy ; Female ; Male ; Middle Aged ; Primary Health Care ; Aged ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/administration & dosage ; Biphenyl Compounds/therapeutic use ; Prospective Studies ; Portugal ; Tetrazoles/therapeutic use ; Tetrazoles/administration & dosage ; Benzimidazoles/therapeutic use ; Amlodipine/therapeutic use ; Amlodipine/administration & dosage ; Practice Guidelines as Topic ; Physicians, Family ; Blood Pressure/drug effects ; Adult
    Chemical Substances Antihypertensive Agents ; Biphenyl Compounds ; Tetrazoles ; candesartan (S8Q36MD2XX) ; Benzimidazoles ; Amlodipine (1J444QC288)
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1170048-8
    ISSN 1651-1999 ; 1651-2480 ; 0803-7051 ; 0803-8023
    ISSN (online) 1651-1999 ; 1651-2480
    ISSN 0803-7051 ; 0803-8023
    DOI 10.1080/08037051.2024.2345887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Advancing the assessment of pacifier effects with a novel computational method.

    Pereira, R / Romero, J / Norton, A / Nóbrega, J M

    BMC oral health

    2024  Volume 24, Issue 1, Page(s) 87

    Abstract: Background: Numerous studies have demonstrated a high likelihood of malocclusions resulting from non-nutritive sucking. Consequently, quantifying the impact of pacifiers can potentially aid in preventing the development or exacerbation of malocclusions ... ...

    Abstract Background: Numerous studies have demonstrated a high likelihood of malocclusions resulting from non-nutritive sucking. Consequently, quantifying the impact of pacifiers can potentially aid in preventing the development or exacerbation of malocclusions and guide the design of improved performance pacifiers.
    Methods: This work proposes and assesses a computational methodology that can effectively gather crucial information and provide more precise data regarding the consequences of non-nutritive pacifier sucking. The computational framework utilized is based on solids4Foam [1, 2], a collection of numerical solvers developed within the OpenFOAM® computational library [3]. The computational model focuses on the palate of a six-month-old baby and incorporates various components such as palate tissues, pacifier and tongue, and considers the negative intraoral pressure generated and the tongue displacement. Different models were tested, each offering varying levels of detail in representing the palate structure. These models range from a simplified approach, with one tissue, to a more intricate representation, involving up to five different tissues, offering a more comprehensive palate model compared to existing literature.
    Results: The analysis of results involved examining the distribution of stress on the palate surface, as well as the displacement and forces exerted on the dental crowns. By comparing the obtained results, it was possible to evaluate the precision of the approaches previously described in the literature. The findings revealed that the predictions were less accurate when using the simplified model with a single tissue for the palate, which is the most common approach proposed in the literature. In contrast, the results demonstrated that the palate model with the most intricate structure, incorporating five different tissues, yielded distinct outcomes compared to all other combinations.
    Conclusions: The computational methodology proposed, employing the most detailed palate model, has demonstrated its effectiveness and necessity in obtaining accurate data on the impact of non-nutritive sucking habits, which are recognized as a primary contributor to the development of dental malocclusions. In the future, this approach could be extended to conduct similar studies encompassing diverse pacifier designs, sizes, and age groups. This would foster the design of innovative pacifiers that mitigate the adverse effects of non-nutritive sucking on orofacial structures.
    MeSH term(s) Infant ; Humans ; Female ; Malocclusion/etiology ; Pacifiers/adverse effects ; Sucking Behavior ; Habits ; Tongue ; Breast Feeding
    Language English
    Publishing date 2024-01-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03848-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Tear down academic paywall during pandemic.

    Costa-Pereira, R

    Brazilian journal of biology = Revista brasleira de biologia

    2020  Volume 80, Issue 3, Page(s) 697

    MeSH term(s) Pandemics
    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2036257-2
    ISSN 1678-4375 ; 1519-6984
    ISSN (online) 1678-4375
    ISSN 1519-6984
    DOI 10.1590/1519-6984.237887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hospital Professionals as Dual Agents: A Superordinate Identity to Solve Interprofessional Conflicts in Hospitals? Comment on "Dual Agency in Hospitals: What Strategies Do Managers and Physicians Apply to Reconcile Dilemmas Between Clinical and Economic Considerations?"

    Cascón-Pereira, Rosalía

    International journal of health policy and management

    2022  Volume 11, Issue 10, Page(s) 2343–2345

    Abstract: The inherent conflict between economic and clinical considerations, between professionalism and managerialism, and between being a manager or being a clinician is widely acknowledged in the sociology of professions. The original article by Waitzberg and ... ...

    Abstract The inherent conflict between economic and clinical considerations, between professionalism and managerialism, and between being a manager or being a clinician is widely acknowledged in the sociology of professions. The original article by Waitzberg and colleagues focused on how hospital professionals reconcile these conflicting demands. In this commentary, we argue that their assumption that the considered hospital professionals (managers, chief financial officers [CFOs], chief physicians and practising physicians) are dual agents moves on from the unproductive debates of inherent conflicts to envisage possibilities of reconciling economic and clinical considerations. We conclude that the instrumental use of the term dual agent to include "the other" (the manager or the clinician) in a superlative and inclusive category can be considered a reframing strategy to solve inherent interprofessional conflicts and to implement more collaborative models in healthcare.
    MeSH term(s) Humans ; Hospitals ; Physicians ; Delivery of Health Care ; Interprofessional Relations
    Language English
    Publishing date 2022-03-02
    Publishing country Iran
    Document type Journal Article ; Comment
    ZDB-ID 2724317-5
    ISSN 2322-5939 ; 2322-5939
    ISSN (online) 2322-5939
    ISSN 2322-5939
    DOI 10.34172/ijhpm.2022.6928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Morphological and Molecular Bases of Male Infertility: A Closer Look at Sperm Flagellum.

    Pereira, Rute / Sousa, Mário

    Genes

    2023  Volume 14, Issue 2

    Abstract: Infertility is a major health problem worldwide without an effective therapy or cure. It is estimated to affect 8-12% of couples in the reproductive age group, equally affecting both genders. There is no single cause of infertility, and its knowledge is ... ...

    Abstract Infertility is a major health problem worldwide without an effective therapy or cure. It is estimated to affect 8-12% of couples in the reproductive age group, equally affecting both genders. There is no single cause of infertility, and its knowledge is still far from complete, with about 30% of infertile couples having no cause identified (named idiopathic infertility). Among male causes of infertility, asthenozoospermia (i.e., reduced sperm motility) is one of the most observed, being estimated that more than 20% of infertile men have this condition. In recent years, many researchers have focused on possible factors leading to asthenozoospermia, revealing the existence of many cellular and molecular players. So far, more than 4000 genes are thought to be involved in sperm production and as regulators of different aspects of sperm development, maturation, and function, and all can potentially cause male infertility if mutated. In this review, we aim to give a brief overview of the typical sperm flagellum morphology and compile some of the most relevant information regarding the genetic factors involved in male infertility, with a focus on sperm immotility and on genes related to sperm flagellum development, structure, or function.
    MeSH term(s) Male ; Humans ; Female ; Sperm Tail ; Asthenozoospermia/complications ; Asthenozoospermia/genetics ; Semen ; Sperm Motility ; Infertility, Male/genetics
    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes14020383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Impact of Lipid Metabolism on Macrophage Polarization: Implications for Inflammation and Tumor Immunity.

    Vassiliou, Evros / Farias-Pereira, Renalison

    International journal of molecular sciences

    2023  Volume 24, Issue 15

    Abstract: Macrophage polarization is influenced by lipids, which also exert significant control over macrophage functions. Lipids and their metabolites are players in intricate signaling pathways that modulate macrophages' responses to pathogens, phagocytosis, ... ...

    Abstract Macrophage polarization is influenced by lipids, which also exert significant control over macrophage functions. Lipids and their metabolites are players in intricate signaling pathways that modulate macrophages' responses to pathogens, phagocytosis, ferroptosis, and inflammation. This review focuses on lipid metabolism and macrophage functions and addresses potential molecular targets for the treatment of macrophage-related diseases. While lipogenesis is crucial for lipid accumulation and phagocytosis in M1 macrophages, M2 macrophages likely rely on fatty acid β-oxidation to utilize fatty acids as their primary energy source. Cholesterol metabolism, regulated by factors such as SREBPs, PPARs, and LXRs, is associated with the cholesterol efflux capacity and the formation of foam cells (M2-like macrophages). Foam cells, which are targets for atherosclerosis, are associated with an increase in inflammatory cytokines. Lipolysis and fatty acid uptake markers, such as CD36, also contribute to the production of cytokines. Enhancing the immune system through the inhibition of lipid-metabolism-related factors can potentially serve as a targeted approach against tumor cells. Cyclooxygenase inhibitors, which block the conversion of arachidonic acid into various inflammatory mediators, influence macrophage polarization and have generated attention in cancer research.
    MeSH term(s) Lipid Metabolism/immunology ; Cell Polarity/immunology ; Inflammation/immunology ; Neoplasms/immunology ; Macrophages/immunology ; Cholesterol/metabolism ; Fatty Acids/metabolism ; Ferroptosis ; Humans
    Chemical Substances Cholesterol (97C5T2UQ7J) ; Fatty Acids
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241512032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Therapist self-awareness and perception of actual performance: the effects of listening to one recorded session.

    Pereira, Raquel / Pires, António Pazo / Neto, David

    Research in psychotherapy (Milano)

    2024  Volume 27, Issue 1

    Abstract: Research in psychotherapy has emphasized the relevance of the therapist's role, particularly the impact of deliberate practice and self-awareness (SA). This study aims to explore how SA is presented in the accounts of psychotherapists and assess the ... ...

    Abstract Research in psychotherapy has emphasized the relevance of the therapist's role, particularly the impact of deliberate practice and self-awareness (SA). This study aims to explore how SA is presented in the accounts of psychotherapists and assess the impact of attending to actual performance. Twenty cognitive behavioral therapy psychotherapists in training were interviewed before and after listening to their session recordings. The interview was based on five domains of self-awareness: recognition of emotional experience, assessment of personal skills, recognition of prejudices and implicit biases, and awareness of personal values. Results show that SA is frequently attained in skills identification and emotional experience. Recognizing the influence of personal values and bias, and emotional regulation was less frequently identified. There were minor differences before and after listening to the recording. There is an increase of SA in identifying the therapist's personal skills, and aspects such as our prejudices and biases are more internalized and difficult to change. This article suggests the importance of deliberate practice strategies to promote SA and increase the effectiveness of psychotherapy.
    Language English
    Publishing date 2024-02-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2654235-3
    ISSN 2239-8031 ; 2239-8031
    ISSN (online) 2239-8031
    ISSN 2239-8031
    DOI 10.4081/ripppo.2024.722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Perception of maxillary incisor inclination and its correlation with dental cephalometric measurements.

    Palmares, Sara / Caseiro, Rui / Pereira, Rui / Jardim, Luís

    Journal of orthodontics

    2024  , Page(s) 14653125241248663

    Abstract: Objective: To correlate the clinical perception of maxillary incisor inclination from photographs of the smiling face with cephalometric measurements, using conventional incisor axis reference points and crown reference points.: Design: Cross- ... ...

    Abstract Objective: To correlate the clinical perception of maxillary incisor inclination from photographs of the smiling face with cephalometric measurements, using conventional incisor axis reference points and crown reference points.
    Design: Cross-sectional study.
    Setting: Department of Orthodontics, School of Dentistry, University of Lisbon (Portugal).
    Participants: Eight orthodontists.
    Methods: The perception of maxillary incisor inclination of 47 female patients (mean age 23.4 ± 1.5 years) was evaluated by eight orthodontists. The participants' photographs (smiling frontal, smiling three-quarter and smiling profile) were shown to each assessor and a continuous visual analogue rating scale was used to assess the perception of maxillary incisor inclination. Pearson's correlation and linear regression were calculated between each cephalometric measurement and the perception of incisor inclination.
    Results: Anatomical crown inclination measurements U1ac-FH (r = 0.854;
    Conclusion: Cephalometric measurements of the labial surface of the anatomical crown of the maxillary incisors showed the strongest correlations with the clinical perception of maxillary incisor inclination from photographs. For optimal aesthetics, the inclination of the labial surface of maxillary incisor crown should be evaluated.
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2011954-9
    ISSN 1465-3133 ; 0301-228X ; 1465-3125
    ISSN (online) 1465-3133
    ISSN 0301-228X ; 1465-3125
    DOI 10.1177/14653125241248663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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