Article ; Online: Effects of aging on cortical representations of continuous speech.
2023 Volume 129, Issue 6, Page(s) 1359–1377
Abstract: Understanding speech in a noisy environment is crucial in day-to-day interactions and yet becomes more challenging with age, even for healthy aging. Age-related changes in the neural mechanisms that enable speech-in-noise listening have been investigated ...
| Abstract | Understanding speech in a noisy environment is crucial in day-to-day interactions and yet becomes more challenging with age, even for healthy aging. Age-related changes in the neural mechanisms that enable speech-in-noise listening have been investigated previously; however, the extent to which age affects the timing and fidelity of encoding of target and interfering speech streams is not well understood. Using magnetoencephalography (MEG), we investigated how continuous speech is represented in auditory cortex in the presence of interfering speech in younger and older adults. Cortical representations were obtained from neural responses that time-locked to the speech envelopes with speech envelope reconstruction and temporal response functions (TRFs). TRFs showed three prominent peaks corresponding to auditory cortical processing stages: early (∼50 ms), middle (∼100 ms), and late (∼200 ms). Older adults showed exaggerated speech envelope representations compared with younger adults. Temporal analysis revealed both that the age-related exaggeration starts as early as ∼50 ms and that older adults needed a substantially longer integration time window to achieve their better reconstruction of the speech envelope. As expected, with increased speech masking envelope reconstruction for the attended talker decreased and all three TRF peaks were delayed, with aging contributing additionally to the reduction. Interestingly, for older adults the late peak was delayed, suggesting that this late peak may receive contributions from multiple sources. Together these results suggest that there are several mechanisms at play compensating for age-related temporal processing deficits at several stages but which are not able to fully reestablish unimpaired speech perception. |
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| MeSH term(s) | Speech/physiology ; Auditory Perception ; Noise ; Speech Perception/physiology ; Acoustic Stimulation/methods | |||||
| Language | English | |||||
| Publishing date | 2023-04-25 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, N.I.H., Extramural | |||||
| ZDB-ID | 80161-6 | |||||
| ISSN | 1522-1598 ; 0022-3077 | |||||
| ISSN (online) | 1522-1598 | |||||
| ISSN | 0022-3077 | |||||
| DOI | 10.1152/jn.00356.2022 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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