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  1. Article ; Online: Brain Abscesses After Endovascular Embolization of a Brain Arteriovenous Malformation with Squid.

    Jabre, Roland / Bernat, Anne-Laure / Peres, Roxane / Froelich, Sébastien

    World neurosurgery

    2019  Volume 132, Page(s) 29–32

    Abstract: Background: The use of nonadhesive liquid embolic agents (NALEAs) has gained great popularity in the treatment of brain vascular malformations, with a lower rate of local complications than surgery. However, we describe the formation of brain abscesses ... ...

    Abstract Background: The use of nonadhesive liquid embolic agents (NALEAs) has gained great popularity in the treatment of brain vascular malformations, with a lower rate of local complications than surgery. However, we describe the formation of brain abscesses after endovascular treatment of a brain arteriovenous malformation (bAVM) and how important removal of the NALEAs was in the treatment of these abscesses.
    Case description: A 68-year-old man presented with seizures after being treated for an unruptured bAVM using Squid (Emboflu), an NALEA. Radiologic imaging revealed brain lesions suspicious of abscesses around the previously treated bAVM. A surgical excision of the bAVM and the embolized material was performed as was drainage of the brain abscesses. Bacterial cultures were positive for Enterococcus faecalis, and the patient left the hospital with an appropriate antibiotic regimen without new deficits.
    Conclusions: This is the first reported case of a bAVM treated with Squid complicated with brain abscesses, a rare but very serious complication. This complication should be treated not only using antibiotherapy but with complete safe removal of the embolic material.
    MeSH term(s) Aged ; Brain Abscess/diagnostic imaging ; Brain Abscess/surgery ; Embolization, Therapeutic ; Enterococcus faecalis ; Gram-Positive Bacterial Infections/diagnostic imaging ; Gram-Positive Bacterial Infections/surgery ; Humans ; Intracranial Arteriovenous Malformations/therapy ; Magnetic Resonance Imaging ; Male ; Microsurgery ; Polyvinyls/therapeutic use
    Chemical Substances Polyvinyls ; ethylene-vinyl alcohol copolymer (25067-34-9)
    Language English
    Publishing date 2019-08-23
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2019.08.095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
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  2. Article ; Online: Alterations of the cerebral cortex in sporadic small vessel disease: A systematic review of in vivo MRI data.

    Peres, Roxane / De Guio, François / Chabriat, Hugues / Jouvent, Eric

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

    2016  Volume 36, Issue 4, Page(s) 681–695

    Abstract: Cerebral small vessel diseases of the brain are a major determinant of cognitive impairment in the elderly. In small vessel diseases, the most easily identifiable lesions, both at post-mortem evaluation and magnetic resonance imaging, lie in subcortical ... ...

    Abstract Cerebral small vessel diseases of the brain are a major determinant of cognitive impairment in the elderly. In small vessel diseases, the most easily identifiable lesions, both at post-mortem evaluation and magnetic resonance imaging, lie in subcortical areas. However, recent results obtained post-mortem, particularly in severe cases, have highlighted the burden of cortex lesions such as microinfarcts and diffuse neuronal loss. The recent development of image post-processing methods allows now assessing in vivo multiple aspects of the cerebral cortex. This systematic review aimed to analyze in vivo magnetic resonance imaging studies evaluating cortex alterations at different stages of small vessel diseases. Studies assessing the relationships between small vessel disease magnetic resonance imaging markers obtained at the subcortical level and cortex estimates were reviewed both in community-dwelling elderly and in patients with symptomatic small vessel diseases. Thereafter, studies analyzing cortex estimates in small vessel disease patients compared with healthy subjects were evaluated. The results support that important cortex alterations develop along the course of small vessel diseases independently of concomitant neurodegenerative processes. Easy detection and quantification of cortex changes in small vessel diseases as well as understanding their underlying mechanisms are challenging tasks for better understanding cognitive decline in small vessel diseases.
    MeSH term(s) Animals ; Cerebral Cortex/pathology ; Cerebral Small Vessel Diseases/pathology ; Humans ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging/methods
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 604628-9
    ISSN 1559-7016 ; 0271-678X
    ISSN (online) 1559-7016
    ISSN 0271-678X
    DOI 10.1177/0271678X15625352
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  3. Article ; Online: Endovascular treatment of ischemic stroke due to isolated internal carotid artery occlusion: ETIS registry data analysis.

    Ter Schiphorst, Adrien / Peres, Roxane / Dargazanli, Cyril / Blanc, Raphaël / Gory, Benjamin / Richard, Sébastien / Marnat, Gaultier / Sibon, Igor / Guillon, Benoit / Bourcier, Romain / Denier, Christian / Spelle, Laurent / Labreuche, Julien / Consoli, Arturo / Lapergue, Bertrand / Costalat, Vincent / Obadia, Michael / Arquizan, Caroline

    Journal of neurology

    2022  Volume 269, Issue 8, Page(s) 4383–4395

    Abstract: Background: The best treatment for acute ischemic stroke (AIS) due to isolated cervical internal carotid artery occlusion (CICAO) (i.e., without associated occlusion of the circle of Willis) is still unknown. In this study, we aimed to describe EVT ... ...

    Abstract Background: The best treatment for acute ischemic stroke (AIS) due to isolated cervical internal carotid artery occlusion (CICAO) (i.e., without associated occlusion of the circle of Willis) is still unknown. In this study, we aimed to describe EVT safety and clinical outcome in patients with CICAO.
    Methods: We analyzed data of all consecutive patients, included in the Endovascular Treatment in Ischemic Stroke (ETIS) Registry between 2013 and 2020, who presented AIS and proven CICAO on angiogram and underwent EVT. We assessed carotid recanalization, procedural complications, National Institutes of Health Stroke Scale (NIHSS) at 24 h post-EVT, and 3-month favorable outcome (modified Rankin Scale, mRS ≤ 2 or equal to the pre-stroke value).
    Results: Forty-five patients were included (median age: 70 years; range: 62-82 years). The median NIHSS before EVT was 14 (9-21). Carotid stenting was performed in 23 (51%) patients. Carotid recanalization at procedure end and on control imaging was observed in 37 (82%) and 29 (70%) patients, respectively. At day 1 post-EVT, the NIHSS remained stable or decreased in 25 (60%) patients; 12 (29%) patients had early neurologic deterioration (NIHSS ≥ 4 points). The rate of procedural complications was 36%, including stent thrombosis (n = 7), intracranial embolism (n = 7), and symptomatic intracranial hemorrhage (n = 1). At 3 months, 18 (40%) patients had a favorable outcome, and 10 (22%) were dead.
    Conclusion: Our study suggests that EVT in AIS patients with moderate/severe initial deficit due to CICAO led to high rate of recanalization at day 1, and a 40% rate of favorable outcome at 3 months. There was a high rate of procedural complication which is of concern. Randomized controlled trials assessing the superiority of EVT in patients with CICAO and severe deficits are needed.
    MeSH term(s) Aged ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/surgery ; Carotid Artery Diseases/etiology ; Carotid Artery, Internal/diagnostic imaging ; Carotid Artery, Internal/surgery ; Data Analysis ; Endovascular Procedures/adverse effects ; Humans ; Ischemic Stroke ; Registries ; Stroke/diagnostic imaging ; Stroke/etiology ; Stroke/surgery ; Thrombectomy/methods ; Thrombosis/complications ; Treatment Outcome
    Language English
    Publishing date 2022-03-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-022-11078-y
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  4. Article ; Online: Clinical Outcome of Acute Ischemic Strokes in Patients with COVID-19.

    Calmettes, Julie / Peres, Roxane / Goncalves, Bruno / Varlan, David / Turc, Guillaume / Obadia, Michael / Nardin, Clotilde / Meppiel, Elodie / De Broucker, Thomas / Mazighi, Mikael / Lyoubi, Aicha

    Cerebrovascular diseases (Basel, Switzerland)

    2021  Volume 50, Issue 4, Page(s) 412–419

    Abstract: Introduction: Acute ischemic stroke (AIS) and thrombotic events (TEs) were reported in patients with COVID-19. Clinical outcome of AIS in the course of COVID-19 remains unknown. We compared early clinical outcome and mortality of COVID-positive (+) ... ...

    Abstract Introduction: Acute ischemic stroke (AIS) and thrombotic events (TEs) were reported in patients with COVID-19. Clinical outcome of AIS in the course of COVID-19 remains unknown. We compared early clinical outcome and mortality of COVID-positive (+) patients admitted for AIS with COVID-negative (-) ones. We hypothesized that COVID+ patients would have poorer clinical outcomes and present a higher rate of TEs and mortality compared with COVID- ones.
    Methods: In this multicentric observational retrospective study, we enrolled patients over 18 years old admitted for AIS in 3 stroke units of the Parisian region during lockdown from March 17, 2020, to May 2, 2020. COVID-19 status as well as demographic, clinical, biological, and imaging data was collected retrospectively from medical records. Poor outcome was defined as modified Rankin score (mRS) 3-6 (3-6) at discharge. We also compared TE frequency and mortality rate through a composite criterion in both groups.
    Results: Two hundred and sixteen patients were enrolled; mean age was 68 years old, and 63% were male. Forty patients were CO-VID+ (18.5%) and 176 were COVID-. Obesity was statistically more frequent in the COVID+ group (36 vs. 13% p < 0.01). The percentage of patients with mRS (3-6) at discharge was higher in the COVID+ group compared with the COVID- group (60 vs. 41%, p = 0.034). The main predictor of presenting a mRS (3-6) at discharge was high NIHSS score at admission (OR, CI 95%: 1.325, 1.22-1.43). Mortality rate was higher in the COVID+ group (12 vs. 3.4%, p = 0.033) as well as TE frequency (15 vs. 2.8%, p < 0.01).
    Conclusion: In this study, patients with AIS infected by SARS-CoV-2 showed a poorer early outcome than COVID- ones. However, when compared to other factors, COVID-19 was not a significant predictor of poor outcome. Vascular morbidity and mortality rates were significantly higher in the COVID+ group compared with the COVID- group.
    MeSH term(s) Aged ; Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/physiopathology ; Case-Control Studies ; Diabetes Mellitus/epidemiology ; Female ; France/epidemiology ; Functional Status ; Hospital Mortality ; Humans ; Ischemic Stroke/epidemiology ; Ischemic Stroke/physiopathology ; Male ; Middle Aged ; Obesity/epidemiology ; Prognosis ; Retrospective Studies ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2021-03-30
    Publishing country Switzerland
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1069462-6
    ISSN 1421-9786 ; 1015-9770
    ISSN (online) 1421-9786
    ISSN 1015-9770
    DOI 10.1159/000514562
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    Zs.A 3181: Show issues Location:
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  5. Article ; Online: Intracranial Extension of Extracranial Vertebral Dissection Is Associated With an Increased Risk of Ischemic Events.

    Di Meglio, Lucas / Mazighi, Mikael / Reiner, Peggy / Peres, Roxane / Guichard, Jean Pierre / Labeyrie, Marc-Antoine / Debette, Stéphanie / Chabriat, Hugues / Cognat, Emmanuel

    Stroke

    2019  Volume 50, Issue 8, Page(s) 2231–2233

    Abstract: Background and Purpose- Intracranial artery dissection can eventually lead to subarachnoid or intracerebral hemorrhage. Little is known about the clinical features and risks associated with extracranial vertebral artery dissection that extends ... ...

    Abstract Background and Purpose- Intracranial artery dissection can eventually lead to subarachnoid or intracerebral hemorrhage. Little is known about the clinical features and risks associated with extracranial vertebral artery dissection that extends intracranially. The clinical and imaging characteristics of extracranial vertebral artery dissection (eVAD) with (e+iVAD) or without (eVAD) intracranial extension were analyzed. Methods- The frequency of ischemic events, including ischemic strokes and transient ischemic attacks, was compared between e+iVAD and eVAD patients from a monocentric cohort study. Results- Among 328 patients with cervical artery dissection, vertebral artery dissection was diagnosed in 153 individuals. Twenty-nine patients had e+iVAD (19%) and 124 patients had only eVAD (81%). Cardiovascular risk factors did not differ between these 2 groups, but ischemic events were more frequent in patients with e+iVAD than in patients with eVAD (86% versus 48%, P=0.0002). Subarachnoid hemorrhage occurred in 1 patient with e+iVAD and in 9 with eVAD (6% versus 3%, P=0.53). Intracranial extension was an independent factor associated with ischemic stroke at admission (odds ratio, 6.43; 95% CI, -1.96 to 21.08; P=0.002) after adjustment for cardiovascular risk factors and imaging findings. Conclusions- In a large cohort of patients with vertebral artery dissection, intracranial extension of the vessel dissection appears associated with an increased risk of ischemic stroke.
    MeSH term(s) Adult ; Brain Ischemia/etiology ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Stroke/etiology ; Vertebral Artery Dissection/complications
    Language English
    Publishing date 2019-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.119.025227
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  6. Article ; Online: Letter to the editor: Serum anti-Aβ antibodies in cerebral amyloid angiopathy.

    Chantran, Yannick / Capron, Jean / Doukhi, Diana / Felix, Johanna / Féroul, Mélanie / Kruse, Florian / Chaigneau, Thomas / Dorothée, Guillaume / Allou, Thibault / Ayrignac, Xavier / Barrou, Zina / de Broucker, Thomas / Cret, Corina / Turc, Guillaume / Peres, Roxane / Wacongne, Anne / Sarazin, Marie / Renard, Dimitri / Cordonnier, Charlotte /
    Alamowitch, Sonia / Aucouturier, Pierre

    Autoimmunity reviews

    2021  Volume 20, Issue 8, Page(s) 102870

    MeSH term(s) Amyloid beta-Peptides ; Cerebral Amyloid Angiopathy/diagnosis ; Humans ; Peptide Fragments
    Chemical Substances Amyloid beta-Peptides ; Peptide Fragments
    Language English
    Publishing date 2021-06-10
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2021.102870
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  7. Article ; Online: Global Impact of COVID-19 on Stroke Care and IV Thrombolysis.

    Nogueira, Raul G / Qureshi, Muhammad M / Abdalkader, Mohamad / Martins, Sheila Ouriques / Yamagami, Hiroshi / Qiu, Zhongming / Mansour, Ossama Yassin / Sathya, Anvitha / Czlonkowska, Anna / Tsivgoulis, Georgios / Aguiar de Sousa, Diana / Demeestere, Jelle / Mikulik, Robert / Vanacker, Peter / Siegler, James E / Kõrv, Janika / Biller, Jose / Liang, Conrad W / Sangha, Navdeep S /
    Zha, Alicia M / Czap, Alexandra L / Holmstedt, Christine Anne / Turan, Tanya N / Ntaios, George / Malhotra, Konark / Tayal, Ashis / Loochtan, Aaron / Ranta, Annamarei / Mistry, Eva A / Alexandrov, Anne W / Huang, David Y / Yaghi, Shadi / Raz, Eytan / Sheth, Sunil A / Mohammaden, Mahmoud H / Frankel, Michael / Bila Lamou, Eric Guemekane / Aref, Hany M / Elbassiouny, Ahmed / Hassan, Farouk / Menecie, Tarek / Mustafa, Wessam / Shokri, Hossam M / Roushdy, Tamer / Sarfo, Fred S / Alabi, Tolulope Oyetunde / Arabambi, Babawale / Nwazor, Ernest O / Sunmonu, Taofiki Ajao / Wahab, Kolawole / Yaria, Joseph / Mohammed, Haytham Hussein / Adebayo, Philip B / Riahi, Anis D / Sassi, Samia Ben / Gwaunza, Lenon / Ngwende, Gift Wilson / Sahakyan, David / Rahman, Aminur / Ai, Zhibing / Bai, Fanghui / Duan, Zhenhui / Hao, Yonggang / Huang, Wenguo / Li, Guangwen / Li, Wei / Liu, Ganzhe / Luo, Jun / Shang, Xianjin / Sui, Yi / Tian, Ling / Wen, Hongbin / Wu, Bo / Yan, Yuying / Yuan, Zhengzhou / Zhang, Hao / Zhang, Jun / Zhao, Wenlong / Zi, Wenjie / Leung, Thomas W / Chugh, Chandril / Huded, Vikram / Menon, Bindu / Pandian, Jeyaraj Durai / Sylaja, P N / Usman, Fritz Sumantri / Farhoudi, Mehdi / Hokmabadi, Elyar Sadeghi / Horev, Anat / Reznik, Anna / Sivan Hoffmann, Rotem / Ohara, Nobuyuki / Sakai, Nobuyuki / Watanabe, Daisuke / Yamamoto, Ryoo / Doijiri, Ryosuke / Tokuda, Naoki / Yamada, Takehiro / Terasaki, Tadashi / Yazawa, Yukako / Uwatoko, Takeshi / Dembo, Tomohisa / Shimizu, Hisao / Sugiura, Yuri / Miyashita, Fumio / Fukuda, Hiroki / Miyake, Kosuke / Shimbo, Junsuke / Sugimura, Yusuke / Yagita, Yoshiki / Takenobu, Yohei / Matsumaru, Yuji / Yamada, Satoshi / Kono, Ryuhei / Kanamaru, Takuya / Yamazaki, Hidekazu / Sakaguchi, Manabu / Todo, Kenichi / Yamamoto, Nobuaki / Sonoda, Kazutaka / Yoshida, Tomoko / Hashimoto, Hiroyuki / Nakahara, Ichiro / Kondybayeva, Aida / Faizullina, Kamila / Kamenova, Saltanat / Zhanuzakov, Murat / Baek, Jang-Hyun / Hwang, Yangha / Lee, Jin Soo / Lee, Si Baek / Moon, Jusun / Park, Hyungjong / Seo, Jung Hwa / Seo, Kwon-Duk / Sohn, Sung Il / Young, Chang Jun / Ahdab, Rechdi / Wan Zaidi, Wan Asyraf / Aziz, Zariah Abdul / Basri, Hamidon Bin / Chung, Law Wan / Ibrahim, Aznita Binti / Ibrahim, Khairul Azmi / Looi, Irene / Tan, Wee Yong / Yahya, Nafisah Wan / Groppa, Stanislav / Leahu, Pavel / Al Hashmi, Amal M / Imam, Yahia Zakaria / Akhtar, Naveed / Pineda-Franks, Maria Carissa / Co, Christian Oliver / Kandyba, Dmitriy / Alhazzani, Adel / Al-Jehani, Hosam / Tham, Carol Huilian / Mamauag, Marlie Jane / Venketasubramanian, Narayanaswamy / Chen, Chih-Hao / Tang, Sung-Chun / Churojana, Anchalee / Akil, Esref / Aykaç, Özlem / Ozdemir, Atilla Ozcan / Giray, Semih / Hussain, Syed Irteza / John, Seby / Le Vu, Huynh / Tran, Anh Duc / Nguyen, Huy Hoang / Nhu Pham, Thong / Nguyen, Thang Huy / Nguyen, Trung Quoc / Gattringer, Thomas / Enzinger, Christian / Killer-Oberpfalzer, Monika / Bellante, Flavio / De Blauwe, Sofie / Vanhooren, Geert / De Raedt, Sylvie / Dusart, Anne / Lemmens, Robin / Ligot, Noemie / Pierre Rutgers, Matthieu / Yperzeele, Laetitia / Alexiev, Filip / Sakelarova, Teodora / Bedeković, Marina Roje / Budincevic, Hrvoje / Cindric, Igor / Hucika, Zlatko / Ozretic, David / Saric, Majda Seferovic / Pfeifer, František / Karpowic, Igor / Cernik, David / Sramek, Martin / Skoda, Miroslav / Hlavacova, Helena / Klecka, Lukas / Koutny, Martin / Vaclavik, Daniel / Skoda, Ondrej / Fiksa, Jan / Hanelova, Katerina / Nevsimalova, Miroslava / Rezek, Robert / Prochazka, Petr / Krejstova, Gabriela / Neumann, Jiri / Vachova, Marta / Brzezanski, Henryk / Hlinovsky, David / Tenora, Dusan / Jura, Rene / Jurák, Lubomír / Novak, Jan / Novak, Ales / Topinka, Zdenek / Fibrich, Petr / Sobolova, Helena / Volny, Ondrej / Krarup Christensen, Hanne / Drenck, Nicolas / Klingenberg Iversen, Helle / Simonsen, Claus Z / Truelsen, Thomas Clement / Wienecke, Troels / Vibo, Riina / Gross-Paju, Katrin / Toomsoo, Toomas / Antsov, Katrin / Caparros, Francois / Cordonnier, Charlotte / Dan, Maria / Faucheux, Jean-Marc / Mechtouff, Laura / Eker, Omer / Lesaine, Emilie / Ondze, Basile / Peres, Roxane / Pico, Fernando / Piotin, Michel / Pop, Raoul / Rouanet, Francois / Gubeladze, Tatuli / Khinikadze, Mirza / Lobjanidze, Nino / Tsiskaridze, Alexander / Nagel, Simon / Ringleb, Peter Arthur / Rosenkranz, Michael / Schmidt, Holger / Sedghi, Annahita / Siepmann, Timo / Szabo, Kristina / Thomalla, Götz / Palaiodimou, Lina / Sagris, Dimitrios / Kargiotis, Odysseas / Klivenyi, Peter / Szapary, Laszlo / Tarkanyi, Gabor / Adami, Alessandro / Bandini, Fabio / Calabresi, Paolo / Frisullo, Giovanni / Renieri, Leonardo / Sangalli, Davide / Pirson, Anne / Uyttenboogaart, Maarten / van den Wijngaard, Ido / Kristoffersen, Espen Saxhaug / Brola, Waldemar / Fudala, Małgorzata / Horoch-Lyszczarek, Ewa / Karlinski, Michal / Kazmierski, Radoslaw / Kram, Pawel / Rogoziewicz, Marcin / Kaczorowski, Rafal / Luchowski, Piotr / Sienkiewicz-Jarosz, Halina / Sobolewski, Piotr / Fryze, Waldemar / Wisniewska, Anna / Wiszniewska, Malgorzata / Ferreira, Patricia / Ferreira, Paulo / Fonseca, Luisa / Marto, João Pedro / Pinho E Melo, Teresa / Nunes, Ana Paiva / Rodrigues, Miguel / Tedim Cruz, Vítor / Falup-Pecurariu, Cristian / Krastev, Georgi / Mako, Miroslav / de Leciñana, María Alonso / Arenillas, Juan F / Ayo-Martin, Oscar / Cruz Culebras, Antonio / Tejedor, Exuperio Diez / Montaner, Joan / Pérez-Sánchez, Soledad / Tola Arribas, Miguel Angel / Rodriguez Vasquez, Alejandro / Mayza, Michael / Bernava, Gianmarco / Brehm, Alex / Machi, Paolo / Fischer, Urs / Gralla, Jan / Michel, Patrik L / Psychogios, Marios-Nikos / Strambo, Davide / Banerjee, Soma / Krishnan, Kailash / Kwan, Joseph / Butt, Asif / Catanese, Luciana / Demchuk, Andrew M / Field, Thalia / Haynes, Jennifer / Hill, Michael D / Khosravani, Houman / Mackey, Ariane / Pikula, Aleksandra / Saposnik, Gustavo / Scott, Courtney Anne / Shoamanesh, Ashkan / Shuaib, Ashfaq / Yip, Samuel / Barboza, Miguel A / Barrientos, Jose Domingo / Portillo Rivera, Ligia Ibeth / Gongora-Rivera, Fernando / Novarro-Escudero, Nelson / Blanco, Anmylene / Abraham, Michael / Alsbrook, Diana / Altschul, Dorothea / Alvarado-Ortiz, Anthony J / Bach, Ivo / Badruddin, Aamir / Barazangi, Nobl / Brereton, Charmaine / Castonguay, Alicia / Chaturvedi, Seemant / Chaudry, Saqib A / Choe, Hana / Choi, Jae H / Dharmadhikari, Sushrut / Desai, Kinjal / Devlin, Thomas G / Doss, Vinodh T / Edgell, Randall / Etherton, Mark / Farooqui, Mudassir / Frei, Don / Gandhi, Dheeraj / Grigoryan, Mikayel / Gupta, Rishi / Hassan, Ameer E / Helenius, Johanna / Kaliaev, Artem / Kaushal, Ritesh / Khandelwal, Priyank / Khawaja, Ayaz M / Khoury, Naim N / Kim, Benny S / Kleindorfer, Dawn O / Koyfman, Feliks / Lee, Vivien H / Leung, Lester Y / Linares, Guillermo / Linfante, Italo / Lutsep, Helmi L / Macdougall, Lisa / Male, Shailesh / Malik, Amer M / Masoud, Hesham / McDermott, Molly / Mehta, Brijesh P / Min, Jiangyong / Mittal, Manoj / Morris, Jane G / Multani, Sumeet S / Nahab, Fadi / Nalleballe, Krishna / Nguyen, Claude B / Novakovic-White, Roberta / Ortega-Gutierrez, Santiago / Rahangdale, Rahul H / Ramakrishnan, Pankajavalli / Romero, Jose Rafael / Rost, Natalia / Rothstein, Aaron / Ruland, Sean / Shah, Ruchir / Sharma, Malveeka / Silver, Brian / Simmons, Marc / Singh, Abhishek / Starosciak, Amy K / Strasser, Sheryl L / Szeder, Viktor / Teleb, Mohamed / Tsai, Jenny P / Voetsch, Barbara / Balaguera, Oscar / Pujol Lereis, Virginia A / Luraschi, Adriana / Almeida, Marcele Schettini / Cardoso, Fabricio Buchdid / Conforto, Adriana / De Deus Silva, Leonardo / Varrone Giacomini, Luidia / Oliveira Lima, Fabricio / Longo, Alexandre L / Magalhães, Pedro S C / Martins, Rodrigo Targa / Mont'alverne, Francisco / Mora Cuervo, Daissy Liliana / Costa Rebello, Leticia / Valler, Lenise / Zetola, Viviane Flumignan / Lavados, Pablo M / Navia, Victor / Olavarría, Verónica V / Almeida Toro, Juan Manuel / Amaya, Pablo Felipe Ricardo / Bayona, Hernan / Corredor, Angel / Rivera Ordonez, Carlos Eduardo / Mantilla Barbosa, Diana Katherine / Lara, Osvaldo / Patiño, Mauricio R / Diaz Escobar, Luis Fernando / Dejesus Melgarejo Fariña, Donoband Edson / Cardozo Villamayor, Analia / Zelaya Zarza, Adolfo Javier / Barrientos Iman, Danny Moises / Rodriguez Kadota, Liliana / Campbell, Bruce / Hankey, Graeme J / Hair, Casey / Kleinig, Timothy / Ma, Alice / Tomazini Martins, Rodrigo / Sahathevan, Ramesh / Thijs, Vincent / Salazar, Daniel / Yuan-Hao Wu, Teddy / Haussen, Diogo C / Liebeskind, David / Yavagal, Dileep R / Jovin, Tudor G / Zaidat, Osama O / Nguyen, Thanh N

    Neurology

    2021  Volume 96, Issue 23, Page(s) e2824–e2838

    Abstract: Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods.!# ...

    Abstract Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods.
    Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.
    Results: There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] -11.7 to -11.3,
    Conclusions: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Hospitalization ; Humans ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; Stroke/drug therapy ; Stroke/epidemiology ; Thrombolytic Therapy
    Language English
    Publishing date 2021-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000011885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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