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  1. Article ; Online: The True Cause of Death.

    Perissinotto, Carla M

    JAMA

    2022  Volume 328, Issue 1, Page(s) 19–20

    MeSH term(s) Cause of Death
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2022.10406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Isolation in the Time of Covid: What is the True Cost, and How Will we Know?

    Holt-Lunstad, Julianne / Perissinotto, Carla M

    American journal of health promotion : AJHP

    2022  Volume 36, Issue 2, Page(s) 380–382

    MeSH term(s) COVID-19 ; Humans ; Loneliness ; SARS-CoV-2 ; Social Isolation
    Language English
    Publishing date 2022-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645160-3
    ISSN 2168-6602 ; 0890-1171
    ISSN (online) 2168-6602
    ISSN 0890-1171
    DOI 10.1177/08901171211064223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: "Relationships, Very Quickly, Turn to Nothing": Loneliness, Social Isolation, and Adaptation to Changing Social Lives Among Persons Living With Dementia and Care Partners.

    Kotwal, Ashwin A / Allison, Theresa A / Halim, Madina / Garrett, Sarah B / Perissinotto, Carla M / Ritchie, Christine S / Smith, Alexander K / Harrison, Krista L

    The Gerontologist

    2024  Volume 64, Issue 4

    Abstract: Background and objectives: Persons with dementia and their care partners have known risks for loneliness and social isolation throughout the disease trajectory, yet little is described about social lives in a population heterogeneous for disease stage, ... ...

    Abstract Background and objectives: Persons with dementia and their care partners have known risks for loneliness and social isolation throughout the disease trajectory, yet little is described about social lives in a population heterogeneous for disease stage, syndrome type, and setting.
    Research design and methods: We conducted a secondary analysis of qualitative interviews from multiple studies to triangulate responses from a cohort of persons with dementia (n = 24), and active (n = 33) or bereaved (n = 15) care partners diverse in setting, dementia type and stage, and life experience. Interviews explored challenges related to social lives and were analyzed thematically.
    Results: Persons with dementia were on average 80 years old (range: 67-94), 38% female, and 78% diagnosed with Alzheimer's dementia; care partners were on average 67 years old (range: 40-87) and 69% female. We identified 3 primary themes. First, dyads lost external social networks due to complex factors, including discomfort of surrounding social networks, caregiving responsibilities, and progressive cognitive deficits. Second, care partners described disruptions of meaningful dyadic relationships due to progressive cognitive and functional deficits, leading to loneliness and anticipatory grief. Third, adaptive strategies centered on care partners facilitating shared social activities and programs addressing caregiver burden. An overarching theme of disease-course accumulation of barriers to social interactions and constant adaptations was present in all themes.
    Discussion and implications: Isolation and loneliness are a shared experience and source of distress for persons with dementia and care partners. Results can inform interventions tailored to individual needs and disease stages of dyads that enhance social connectedness.
    MeSH term(s) Humans ; Female ; Aged, 80 and over ; Aged ; Male ; Loneliness ; Dementia/psychology ; Caregivers/psychology ; Social Isolation ; Alzheimer Disease
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 216760-8
    ISSN 1758-5341 ; 0016-9013
    ISSN (online) 1758-5341
    ISSN 0016-9013
    DOI 10.1093/geront/gnae014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Meeting the Care Needs of Older Adults Isolated at Home During the COVID-19 Pandemic.

    Steinman, Michael A / Perry, Laura / Perissinotto, Carla M

    JAMA internal medicine

    2020  Volume 180, Issue 6, Page(s) 819–820

    MeSH term(s) Affective Symptoms/psychology ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Caregivers/psychology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/psychology ; Family/psychology ; Home Care Services/organization & administration ; Humans ; Loneliness/psychology ; Mental Health ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/psychology ; Quarantine/psychology ; SARS-CoV-2 ; Social Support ; Telemedicine/methods
    Keywords covid19
    Language English
    Publishing date 2020-04-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2020.1661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Loneliness Among Older Adults.

    Rudy, Ellen T / McNamara, Kelsey C / Parker, Andrew / Kotwal, Ashwin A / Perissinotto, Carla M

    Health affairs (Project Hope)

    2022  Volume 41, Issue 10, Page(s) 1530

    MeSH term(s) Aged ; Humans ; Loneliness
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Letter
    ZDB-ID 632712-6
    ISSN 1544-5208 ; 0278-2715
    ISSN (online) 1544-5208
    ISSN 0278-2715
    DOI 10.1377/hlthaff.2022.00512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Role of Digital Technologies in Facilitating Psychosocial Resilience to Sudden Social Isolation Among Older Adults: Lessons Learned from the COVID-19 Pandemic.

    Newmark, Rebecca L / Allison, Theresa A / Smith, Alexander K / Perissinotto, Carla M / Tha, Soe Han / Kotwal, Ashwin A

    Journal of applied gerontology : the official journal of the Southern Gerontological Society

    2023  Volume 42, Issue 12, Page(s) 2348–2359

    Abstract: This study investigated how older adults adopted new technologies in response to sudden social isolation caused by the COVID-19 pandemic and how this adoption was related to their long-term psychosocial well-being. The study involved a 6-month ... ...

    Abstract This study investigated how older adults adopted new technologies in response to sudden social isolation caused by the COVID-19 pandemic and how this adoption was related to their long-term psychosocial well-being. The study involved a 6-month longitudinal survey of 151 older adults and two phone-based focus groups, which informed a semi-structured interview guide and purposive sampling of diverse community-dwelling older adults. We then conducted twenty qualitative interviews and thematic analysis and mapped themes to 6-month quantitative trajectories of psychosocial health. Three themes emerged: first, most participants adopted multiple technologies to maintain social connection and psychosocial well-being. Second, participants felt left behind by certain technologies due to complicated systems or ageist societal norms. Third, pandemic-related community resources promoted technology independence among isolated older adults and those wanting to avoid "burdening" family. Results challenge ageist stereotypes and provide a framework for encouraging access and comfort with multiple technologies to adapt to sudden health crises or disruptive events.
    MeSH term(s) Humans ; Aged ; Digital Technology ; COVID-19 ; Pandemics ; Resilience, Psychological ; Social Isolation
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 155897-3
    ISSN 1552-4523 ; 0733-4648
    ISSN (online) 1552-4523
    ISSN 0733-4648
    DOI 10.1177/07334648231190228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Meeting the Care Needs of Older Adults Isolated at Home During the COVID-19 Pandemic

    Steinman, Michael A. / Perry, Laura / Perissinotto, Carla M.

    JAMA Internal Medicine

    2020  Volume 180, Issue 6, Page(s) 819

    Keywords Internal Medicine ; covid19
    Language English
    Publisher American Medical Association (AMA)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2020.1661
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Persistent loneliness due to COVID-19 over 18 months of the pandemic: A prospective cohort study.

    Kotwal, Ashwin A / Batio, Stephanie / Wolf, Michael S / Covinsky, Kenneth E / Yoshino Benavente, Julia / Perissinotto, Carla M / O'Conor, Rachel M

    Journal of the American Geriatrics Society

    2022  Volume 70, Issue 12, Page(s) 3469–3479

    Abstract: Background: Loneliness was common early in the COVID-19 pandemic due to physical distancing measures, but little is known about how loneliness persisted into later stages of the pandemic. We therefore examined longitudinal trajectories of loneliness ... ...

    Abstract Background: Loneliness was common early in the COVID-19 pandemic due to physical distancing measures, but little is known about how loneliness persisted into later stages of the pandemic. We therefore examined longitudinal trajectories of loneliness over 18 months of the pandemic and subgroups at risk for persistent loneliness.
    Methods: We used data from the COVID-19 & Chronic Conditions study collected between March 27, 2020 to December 10, 2021, including 641 predominantly older adults with ≥1 chronic condition who completed six interviews at approximately 3 month intervals. Participants reported loneliness (defined as some, most, or all of the time) during the past week due to COVID-19. We used trajectory mixture models to identify clusters of individuals following similar trajectories of loneliness, then determined subgroups likely to be classified in different loneliness trajectories using multivariable regression models adjusted for sociodemographic and clinical covariates.
    Results: Participants were on average 63 years old, 61% female, 30% Black, 20% Latinx, and 29% were living below the poverty level. There was an overall reduction in loneliness over time (March to April/2020: 51% to September to December/2021: 31%, p = 0.01). Four distinct trajectory groups emerged: (1) "Persistent Loneliness" (n = 101, 16%); (2) "Adapted" (n = 141, 22%), individuals who were initially lonely, with feelings of loneliness decreasing over time; (3) "Occasional loneliness" (n = 189, 29%); and (4) "Never lonely" (n = 211, 33%). Subgroups at highest risk of the "Persistently Lonely" trajectory included those identifying as Latinx (aOR 2.5, 95% CI: 1.2, 5.2), or living in poverty (aOR 2.5; 95% CI: 1.4, 4.6).
    Conclusions: Although loneliness declined for a majority of older adults during the pandemic in our sample, persistent loneliness attributed to the COVID-19 pandemic was common (1 in 6 adults), particularly among individuals identifying as Hispanic/Latinx or living in poverty. Interventions addressing loneliness can ease pandemic-related suffering, and may mitigate long-term mental and physical health consequences.
    MeSH term(s) Female ; Humans ; Aged ; Male ; Pandemics ; COVID-19 ; Loneliness ; Prospective Studies ; Physical Distancing
    Language English
    Publishing date 2022-08-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A single question assessment of loneliness in older adults during the COVID-19 pandemic: A nationally-representative study.

    Kotwal, Ashwin A / Cenzer, Irena S / Waite, Linda J / Smith, Alexander K / Perissinotto, Carla M / Hawkley, Louise C

    Journal of the American Geriatrics Society

    2022  Volume 70, Issue 5, Page(s) 1342–1345

    MeSH term(s) Aged ; COVID-19 ; Humans ; Loneliness ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2022-02-12
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17700
    Database MEDical Literature Analysis and Retrieval System OnLINE

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