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  1. Book ; Online: Chapter 42 From Niche to Mainstream

    PERROTTA, Marta

    The Emergence of a Podcasting Culture and Market in the Italian Radio Context

    2022  

    Keywords Media studies ; Broadcast Radio, Journalism, Podcasting, Radio History, Radio Journalism, True Crime Podcast
    Language English
    Size 1 electronic resource (12 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English
    HBZ-ID HT030382611
    ISBN 9781032251646 ; 1032251646
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Blurring the divide: Navigating the public/private landscape of fertility treatment in the UK.

    Hamper, Josie / Perrotta, Manuela

    Health & place

    2023  Volume 80, Page(s) 102992

    Abstract: It is widely assumed that fertility patients in the UK are either privately funded or publicly funded through the National Health Service. This article challenges this distinction and demonstrates how the boundaries between public and private fertility ... ...

    Abstract It is widely assumed that fertility patients in the UK are either privately funded or publicly funded through the National Health Service. This article challenges this distinction and demonstrates how the boundaries between public and private fertility treatment provision are increasingly blurred. It draws on interviews with 42 fertility patients and partners who had accessed in vitro fertilisation (IVF) through both the National Health Service and private providers, to demonstrate how participants were compelled to engage with a consumerist model of healthcare, even when they had access to publicly funded IVF cycles. Patients' experiences of navigating fertility treatment revealed a hybrid public/private consumption landscape, which reflects the uneven process of privatisation across the fertility sector. This article demonstrates how healthcare privatisation has had profound consequences for all IVF patients.
    MeSH term(s) Humans ; State Medicine ; Delivery of Health Care ; United Kingdom
    Language English
    Publishing date 2023-02-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1262540-1
    ISSN 1873-2054 ; 1353-8292
    ISSN (online) 1873-2054
    ISSN 1353-8292
    DOI 10.1016/j.healthplace.2023.102992
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4333: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Accounting for complexity in healthcare innovation debates: Professional views on the use of new IVF treatments.

    Geampana, Alina / Perrotta, Manuela

    Health (London, England : 1997)

    2022  Volume 27, Issue 6, Page(s) 907–923

    Abstract: Social scientists have long been interested in the forces and values driving healthcare innovation. The simultaneous rise of 20th century healthcare reforms, increased importance of evidence and upsurge in lay health activism have shaped modern medicine. ...

    Abstract Social scientists have long been interested in the forces and values driving healthcare innovation. The simultaneous rise of 20th century healthcare reforms, increased importance of evidence and upsurge in lay health activism have shaped modern medicine. On this backdrop, fertility care emerged in the 1970s. Recent developments reveal a contentious relationship between new fertility treatments and clinical evidence, with emerging technologies being used without conclusive evidence of effectiveness despite being sold to patients. Initial critiques of this phenomenon emphasise commercial interests as the culprit, suggesting that the problematic use of unproven treatments is mainly driven by the private sector. Here, we challenge this over-simplified view of IVF care. Drawing on a qualitative analysis of key documents and 43 in-depth professional interviews, this article identifies three main stakeholder approaches to new treatment adoption. We argue that viewpoints are anchored within three critical overarching 'modes of coordination' or core values in modern healthcare: efficiency, effectiveness and patient-centeredness. This analysis encourages a more contextualised overview of fertility care than previous literatures have afforded. The IVF case shows that an emphasis on private versus public clinic practices obscure similarities between the two along with the values motivating healthcare professionals' approaches to new treatments.
    MeSH term(s) Humans ; Delivery of Health Care ; Fertilization in Vitro ; Health Care Reform ; Health Personnel
    Language English
    Publishing date 2022-02-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1338717-0
    ISSN 1461-7196 ; 1363-4593
    ISSN (online) 1461-7196
    ISSN 1363-4593
    DOI 10.1177/13634593221074874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6197: Show issues Location:
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  4. Article ; Online: Patient informed choice in the age of evidence-based medicine: IVF patients' approaches to biomedical evidence and fertility treatment add-ons.

    Perrotta, Manuela / Hamper, Josie

    Sociology of health & illness

    2022  Volume 45, Issue 2, Page(s) 225–241

    Abstract: With the increasing offer of fertility treatment by a largely privatised sector, which has involved the proliferation of treatment add-ons lacking evidence of effectiveness, In-Vitro Fertilisation (IVF) patients are expected to make informed choices on ... ...

    Abstract With the increasing offer of fertility treatment by a largely privatised sector, which has involved the proliferation of treatment add-ons lacking evidence of effectiveness, In-Vitro Fertilisation (IVF) patients are expected to make informed choices on what to include in their treatment. Drawing on interviews with 51 individuals undergoing fertility treatment, this article explores patients' approaches to medical evidence interpretation and its role in their decisions to include add-ons. While most IVF patients share understandings of what counts as medical evidence, our findings show how their approaches also differ. Our analysis focuses on how patients negotiate the notion of medical evidence and its relation to other forms of experience or knowledge. We present four different approaches to evidence in IVF: (1) delegating evaluations of evidence to experts; (2) critically assessing available evidence; (3) acknowledging the process of making evidence; and (4) contextualising evidence in their lived experience of infertility. We suggest that patients' choice to include add-ons is not due to a lack of information on or understanding of evidence, but rather should be interpreted as part of the complexity of patients' experiences of infertility.
    MeSH term(s) Humans ; Evidence-Based Medicine ; Fertilization in Vitro ; Infertility/therapy ; Informed Consent ; Choice Behavior
    Language English
    Publishing date 2022-11-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 795552-2
    ISSN 1467-9566 ; 0141-9889
    ISSN (online) 1467-9566
    ISSN 0141-9889
    DOI 10.1111/1467-9566.13581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2727: Show issues Location:
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  5. Article: Mouse models of cerebral injury and cognitive impairment in hypertension.

    Perrotta, Marialuisa / Carnevale, Daniela / Carnevale, Lorenzo

    Frontiers in aging neuroscience

    2023  Volume 15, Page(s) 1199612

    Abstract: Hypertension is a major risk factor for dementia, including both vascular and neurodegenerative etiologies. With the original aim of studying the effect of blood pressure elevation on canonical target organs of hypertension as the heart, the vasculature ... ...

    Abstract Hypertension is a major risk factor for dementia, including both vascular and neurodegenerative etiologies. With the original aim of studying the effect of blood pressure elevation on canonical target organs of hypertension as the heart, the vasculature or the kidneys, several experimental models of hypertension have sprouted during the years. With the more recent interest of understanding the cerebral injury burden caused by hypertension, it is worth understanding how the main models of hypertension or localized cerebral hypertension stand in the field of hypertension-induced cerebral injury and cognitive impairment. With this review we will report main genetic, pharmacological and surgical models of cognitive impairment induced by hypertension, summarizing how each specific category and model can improve our understanding of the complex phenomenon of cognitive loss of vascular etiology.
    Language English
    Publishing date 2023-07-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2023.1199612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Brain Areas Involved in Modulating the Immune Response Participating in Hypertension and Its Target Organ Damage.

    Perrotta, Marialuisa / Carnevale, Daniela

    Antioxidants & redox signaling

    2021  Volume 35, Issue 18, Page(s) 1515–1530

    Abstract: Significance: ...

    Abstract Significance:
    MeSH term(s) Blood Pressure/physiology ; Brain ; Humans ; Hypertension ; Immunity ; Renin-Angiotensin System
    Language English
    Publishing date 2021-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1483836-9
    ISSN 1557-7716 ; 1523-0864
    ISSN (online) 1557-7716
    ISSN 1523-0864
    DOI 10.1089/ars.2021.0142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: The neurology of hypertension: merging academic specialties to connect heart and brain pathophysiology.

    Lembo, Giuseppe / Perrotta, Marialuisa

    Cardiovascular research

    2021  Volume 117, Issue 5, Page(s) e70–e72

    MeSH term(s) Animals ; Blood Pressure ; Brain/metabolism ; Brain/physiopathology ; Cardiology ; Cardiovascular System/innervation ; Humans ; Hypertension/diagnosis ; Hypertension/metabolism ; Hypertension/physiopathology ; Interdisciplinary Communication ; Neuroimmunomodulation ; Neurosciences ; Signal Transduction
    Language English
    Publishing date 2021-04-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvab089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 565: Show issues Location:
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  8. Article ; Online: Enacting evidence-based medicine in fertility care: Tensions between commercialisation and knowledge standardisation.

    Perrotta, Manuela / Geampana, Alina

    Sociology of health & illness

    2021  Volume 43, Issue 9, Page(s) 2015–2030

    Abstract: In this article we explore the recent enactment of evidence-based medicine (EBM) in the field of fertility care. We aim to contribute to the medical sociology literature through an analysis of how evidence is produced, interpreted and institutionalised ... ...

    Abstract In this article we explore the recent enactment of evidence-based medicine (EBM) in the field of fertility care. We aim to contribute to the medical sociology literature through an analysis of how evidence is produced, interpreted and institutionalised in a relatively new medical field such as in vitro fertilisation (IVF), characterised by high uncertainty due to limited knowledge and high levels of commercialisation. Drawing on extensive ethnographic research conducted in England, this article explores the challenges IVF professionals encounter in producing credible data on the effectiveness of additional treatments, offering novel insights on the tensions between commercialisation and standardisation in the enactment of EBM. Extant medical sociology and Science and Technology Studies literature has shown the hidden professional work required to enact randomised control trials in practice. Our analysis shows that this hidden work is not enough when there is a broader lack of standardisation in both clinical and research practices, as producing 'good quality' evidence requires high levels of standardisation of knowledge production.
    MeSH term(s) England ; Evidence-Based Medicine ; Fertility ; Fertility Preservation ; Fertilization in Vitro ; Humans
    Language English
    Publishing date 2021-09-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 795552-2
    ISSN 1467-9566 ; 0141-9889
    ISSN (online) 1467-9566
    ISSN 0141-9889
    DOI 10.1111/1467-9566.13381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2727: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: The crafting of hope: Contextualising add-ons in the treatment trajectories of IVF patients.

    Perrotta, Manuela / Hamper, Josie

    Social science & medicine (1982)

    2021  Volume 287, Page(s) 114317

    Abstract: The proliferation and popularity of additional treatments in IVF, also known as add-ons, has generated widespread discussion and controversy in the UK, where concerns have addressed the lack of evidence to support the efficacy and safety of these ... ...

    Abstract The proliferation and popularity of additional treatments in IVF, also known as add-ons, has generated widespread discussion and controversy in the UK, where concerns have addressed the lack of evidence to support the efficacy and safety of these treatments, their cost, and their connection to a wider context of privatisation of fertility treatment. Drawing on 42 interviews with IVF patients, this article explores the role of hope in the appeal of add-ons from the patient perspective. The analysis is presented in two parts: firstly, we investigate the role of hope in patients' decision-making on treatment, contextualising add-ons in the broader trajectory of their IVF experience; secondly, we examine how patients navigate the offer of add-ons, focusing on the role of hope in how they rationalise their decisions on whether to include them in their fertility treatment. Our analysis shows how patients craft their hope to navigate the increasing number of available options in their quest to find the treatment(s) that will "work" for them. We suggest that the imperative for patients to explore all options is intensified with the emergence of add-ons, which produces a novel context and version of a "hope technology".
    MeSH term(s) Female ; Fertility ; Fertilization in Vitro ; Humans ; Live Birth ; Pregnancy ; Reproductive Techniques, Assisted
    Language English
    Publishing date 2021-08-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2021.114317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 625: Show issues Location:
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  10. Article: Predicting Success in the Embryology Lab: The Use of Algorithmic Technologies in Knowledge Production.

    Geampana, Alina / Perrotta, Manuela

    Science, technology & human values

    2021  Volume 48, Issue 1, Page(s) 212–233

    Abstract: This article analyzes local algorithmic practices resulting from the increased use of time-lapse (TL) imaging in fertility treatment. The data produced by TL technologies are expected to help professionals pick the best embryo for implantation. The ... ...

    Abstract This article analyzes local algorithmic practices resulting from the increased use of time-lapse (TL) imaging in fertility treatment. The data produced by TL technologies are expected to help professionals pick the best embryo for implantation. The emergence of TL has been characterized by promissory discourses of deeper embryo knowledge and expanded selection standardization, despite professionals having no conclusive evidence that TL improves pregnancy rates. Our research explores the use of TL tools in embryology labs. We pay special attention to standardization efforts and knowledge-creation facilitated through TL and its incorporated algorithms. Using ethnographic data from five UK clinical sites, we argue that knowledge generated through TL is contingent upon complex human-machine interactions that produce local uncertainties. Thus, algorithms do not simply add medical knowledge. Rather, they rearrange professional practice and expertise. Firstly, we show how TL changes lab routines and training needs. Secondly, we show that the human input TL requires renders the algorithm itself an uncertain and situated practice. This, in turn, raises professional questions about the algorithm's authority in embryo selection. The article demonstrates the embedded nature of algorithmic knowledge production, thus pointing to the need for STS scholarship to further explore the locality of algorithms and AI.
    Language English
    Publishing date 2021-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2021122-3
    ISSN 1552-8251 ; 0162-2439
    ISSN (online) 1552-8251
    ISSN 0162-2439
    DOI 10.1177/01622439211057105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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