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Book ; Online: HDPython

Peschke, R. / Nishimura, K. / Varner, G.

A High Level Python Based Object-Oriented HDL Framework

2020

Abstract: We present a High-Level Python-based Hardware Description Language (HDPython), It uses Python as its source language and converts it to standard VHDL. Compared to other approaches of building converters from a high-level programming language into a ... ...

Abstract	We present a High-Level Python-based Hardware Description Language (HDPython), It uses Python as its source language and converts it to standard VHDL. Compared to other approaches of building converters from a high-level programming language into a hardware description language, this new approach aims to maintain an object-oriented paradigm throughout the entire process. Instead of removing all the high-level features from Python to make it into an HDL, this approach goes the opposite way. It tries to show how certain features from a high-level language can be implemented in an HDL, providing the corresponding benefits of high-level programming for the user.
Keywords	Computer Science - Programming Languages
Publishing date	2020-11-04
Publishing country	us
Document type	Book ; Online
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Article ; Online: Serological and faecal detection of Angiostrongylus vasorum in dogs from Austria.

Globokar, Majda / Pantchev, Nikola / Hinney, Barbara / Leschnik, Michael / Peschke, Roman / Schaper, Roland / Schnyder, Manuela

Veterinary parasitology, regional studies and reports

2021 Volume 26, Page(s) 100641

Abstract: Canine angiostrongylosis is a potentially lethal parasitic disease that can manifest itself with a broad spectrum of clinical signs, including respiratory distress, neurological and bleeding disorders, or non-specific signs. The occurrence of ... ...

Abstract	Canine angiostrongylosis is a potentially lethal parasitic disease that can manifest itself with a broad spectrum of clinical signs, including respiratory distress, neurological and bleeding disorders, or non-specific signs. The occurrence of Angiostrongylus vasorum is widely reported in Europe, but very little is known about its presence in Austria. In this first large-scale survey, 1279 sera were collected from Austrian dogs and tested by an ELISA for the detection of circulating antigen of A. vasorum (sensitivity: 95.7%, specificity 94.0%) and by a separate ELISA detecting specific antibodies (sensitivity 81.0%, specificity 98.8%). Furthermore, 1040 faecal samples were tested for the presence of lungworm first stage larvae (L1). One dog (0.1%, 95% confidence intervals [CI]: 0.0-0.4%) was positive in both ELISAs, while 1.2% (n = 15, CI: 0.7-1.9%) of the tested dogs were antigen-positive and 1.5% (n = 19, CI: 0.9-2.3%) were positive for specific antibodies. Overall, 13 dogs (1.3%; CI: 0.7-2.1%) were positive for A. vasorum L1 while 31 dogs were positive for Crenosoma vulpis L1 (3.0%; CI: 2.0-4.2%). One dog shed L1 from both A. vasorum and C. vulpis (0.1%, CI: 0.0-0.5%). Dogs positive for A. vasorum originated from northeast, southeast and south Austria (antigen and/or antibody detection), but also from north, west and southwest Austria (antibody detection) and from northeast and west Austria (L1 detection). One of 88 blood samples (1.1%, CI: 0.0-6.2%) submitted from the eastern part of Austria was positive by a rapid assay for A. vasorum antigen detection (Angio Detect™). Crenosoma vulpis positive samples originated from northwest, north, northeast, south and west Austria. These results confirm the very sporadic occurrence of A. vasorum in the investigated areas of the country. However, due to the substantial infectious pressure from the surrounding countries and the free circulation of dogs and foxes acting as wildlife reservoirs and due to clinical relevance for infected dogs, it is crucial to maintain disease awareness also in areas where the parasite has not yet been detected.
MeSH term(s)	Angiostrongylus ; Animals ; Antibodies, Helminth ; Antigens, Helminth ; Austria/epidemiology ; Dog Diseases/diagnosis ; Dog Diseases/epidemiology ; Dog Diseases/parasitology ; Dogs
Chemical Substances	Antibodies, Helminth ; Antigens, Helminth
Language	English
Publishing date	2021-09-21
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2405-9390
ISSN (online)	2405-9390
DOI	10.1016/j.vprsr.2021.100641
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Article ; Online: Mechanical tools for the removal of Ixodes ricinus female ticks--differences of instruments and pulling or twisting?

Duscher, G G / Peschke, R / Tichy, A

Parasitology research

2012 Volume 111, Issue 4, Page(s) 1505–1511

Abstract: The fast and safe removal of ticks is of medical and veterinary importance since many tick-borne pathogens require time to be transmitted. In the past, many tools and applications were used to remove ticks from the skin of humans and pets. Choking the ... ...

Abstract	The fast and safe removal of ticks is of medical and veterinary importance since many tick-borne pathogens require time to be transmitted. In the past, many tools and applications were used to remove ticks from the skin of humans and pets. Choking the ticks by blocking their respiratory system with chemicals cannot be recommended due to the low respiratory rate of ticks. Mechanical devices to remove ticks are usually recommended; however, they vary with regard to their mechanism of seizing and holding the tick and in the way of extraction (pulling or twisting). In this study, five commercial tick removal devices with different mechanisms were tested on pets according to their practicability, injury of the mouthparts, and the idiosoma of female Ixodes ricinus ticks. Therefore, 22 veterinarians and four pet owners removed 596 ticks from various animals by using the different devices and filled in a questionnaire for each case. The tick species and instars were determined, and for the female I. ricinus ticks (n = 527) the condition of the mouthparts as well as the idiosoma was evaluated. Twisting of the female I. ricinus ticks reduced the force required for extraction, the adverse reaction of the animal and the time needed for removal. The device with a "V"-shaped slot which allows a grabbing of the mouthparts delivered the best results according to the condition of the mouthparts and the intactness of the female I. ricinus tick's body. Therefore, grabbing the mouthparts and twisting can be recommended for removal of I. ricinus females from pets.
MeSH term(s)	Animals ; Equipment and Supplies ; Female ; Ixodes ; Surveys and Questionnaires ; Tick Infestations/therapy ; Tick Infestations/veterinary
Language	English
Publishing date	2012-06-26
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-012-2987-6
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Article ; Online: Reduction of Allergic Lung Disease by Mucosal Application of

Korb, Elke / Drinić, Mirjana / Wagner, Angelika / Geissler, Nora / Inic-Kanada, Aleksandra / Peschke, Roman / Joachim, Anja / Wiedermann, Ursula / Schabussova, Irma

Frontiers in immunology

2021 Volume 11, Page(s) 612766

Abstract: Background: The hygiene hypothesis suggests a link between parasitic infections and immune disorders, such as allergic diseases. We previously showed that infection with : Methods: Mice were intranasally treated with TLA either i) prior to ... ...

Abstract	Background: The hygiene hypothesis suggests a link between parasitic infections and immune disorders, such as allergic diseases. We previously showed that infection with Methods: Mice were intranasally treated with TLA either i) prior to sensitization, ii) during sensitization and challenge, or iii) after sensitization with ovalbumin (OVA). Recruitment of inflammatory cells to the lung, cytokine levels in restimulated lung and spleen cell cultures as well as levels of OVA-specific antibodies in serum were measured. In parallel, the effect of native TLA, heat-inactivated (hiTLA) or deglycosylated TLA (dgTLA) on sensitized splenocytes was evaluated Results: When applied together with OVA i) during systemic sensitization and local challenge or ii) exclusively during local challenge, TLA reduced infiltration of eosinophils into the lung, OVA-specific type 2 cytokines in restimulated lung cell cultures, and partially, type 2 cytokines in restimulated spleen cell cultures in comparison to allergic controls. No beneficial effect was observed when TLA was applied prior to the start of sensitization. Analysis of epitope sugars on TLA indicated a high abundance of mannose, fucose, N-acetylglucosamine, and N-acetylgalactosamine. Deglycosylation of TLA, but not heat-inactivation, abolished the potential of TLA to reduce type 2 responses Conclusion: We showed that mucosal application of TLA reduced the development of experimental allergy in mice. The beneficial effects depended on the timing of the application in relation to the time point of sensitization. Not only co-application, but also therapy in sensitized/allergic animals with native TLA reduced local allergic responses. Furthermore, we show that TLA is highly glycosylated and glycoconjugates seem to play a role in anti-allergic effects. In summary, given the powerful modulatory effect that TLA exhibits, understanding its exact mechanisms of action may lead to the development of novel immunomodulators in clinical application.
MeSH term(s)	Allergens/immunology ; Animals ; Antigens, Protozoan/immunology ; Carbohydrates/immunology ; Cell Line ; Chlorocebus aethiops ; Cytokines/immunology ; Female ; Hypersensitivity/immunology ; Hypersensitivity/parasitology ; Immunologic Factors/immunology ; Lung/immunology ; Lung/parasitology ; Lung Diseases/immunology ; Lung Diseases/parasitology ; Mice ; Mice, Inbred BALB C ; Ovalbumin/immunology ; Respiratory Mucosa/immunology ; Respiratory Mucosa/parasitology ; Spleen/immunology ; Spleen/parasitology ; Toxoplasma/immunology ; Toxoplasmosis/immunology ; Toxoplasmosis/parasitology ; Vero Cells
Chemical Substances	Allergens ; Antigens, Protozoan ; Carbohydrates ; Cytokines ; Immunologic Factors ; Ovalbumin (9006-59-1)
Language	English
Publishing date	2021-03-10
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2020.612766
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Article ; Online: Decay of elevated antibiotic resistance genes in natural river sediments after sedimentation of wastewater particles.

Brown, Philip C / Borowska, Ewa / Peschke, Rafael / Schwartz, Thomas / Horn, Harald

The Science of the total environment

2019 Volume 705, Page(s) 135861

Abstract: Large-scale wastewater treatment plants (WWTPs) discharge hundreds of tons of total suspended solids (TSS) into surface waters every year. Additionally, a comparable amount is released by sewer overflows during heavy rain events in case of combined sewer ...

Abstract	Large-scale wastewater treatment plants (WWTPs) discharge hundreds of tons of total suspended solids (TSS) into surface waters every year. Additionally, a comparable amount is released by sewer overflows during heavy rain events in case of combined sewer systems. Along with sedimentation, particle-attached microorganisms and their antibiotic resistance genes (ARGs) are herewith transported to the riverbed of the receiving water. To better understand the dynamics of this process, a particulate wastewater fraction was added into batch reactors, which were previously filled with natural river sediments and tap water. In parallel, antibiotics (ABs) (erythromycin, tetracycline, ciprofloxacin, roxithromycin, penicillin V, and sulfamethoxazole) were spiked to investigate their capability to select for resistance. The abundance of six ARGs (ermB, tetM, bla
MeSH term(s)	Anti-Bacterial Agents ; Drug Resistance, Microbial ; Genes, Bacterial ; Rivers ; Waste Water
Chemical Substances	Anti-Bacterial Agents ; Waste Water
Language	English
Publishing date	2019-11-30
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2019.135861
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Article ; Online: Application of Western blot analysis for the diagnosis of Encephalitozoon cuniculi infection in rabbits: example of a quantitative approach.

Desoubeaux, Guillaume / Pantin, Ana / Peschke, Roman / Joachim, Anja / Cray, Carolyn

Parasitology research

2017 Volume 116, Issue 2, Page(s) 743–750

Abstract: Diagnosis of Encephalitozoon cuniculi infection in rabbits remains a major veterinary issue. ELISA or immunofluorescence assays are the current reference standards of serological tests. However, these conventional techniques suffer from a lack of ... ...

Abstract	Diagnosis of Encephalitozoon cuniculi infection in rabbits remains a major veterinary issue. ELISA or immunofluorescence assays are the current reference standards of serological tests. However, these conventional techniques suffer from a lack of accuracy for distinguishing active from past infections, as a positive serostatus is common in clinically normal rabbits. In this study, we assessed the diagnostic performance of Western blot (WB) to detect both anti-E. cuniculi immunoglobulin G (IgG) and immunoglobulin M (IgM) in comparison with ELISA and to address the intensity of the immune response through a quantitative approach. Positive WB results were highly correlated with the E. cuniculi-related diseased status (P < 0.0001). Although it was more labor intensive and less standardized, quantitative WB provided detailed comparable analysis regarding the humoral response and diagnostic performance similar to ELISA testing with statistically higher sensitivity (88.4 vs. 76.1% for IgG detection and 84.3 vs. 70.4% for IgM, P < 0.01). Several specific WB bands were shown to be significantly associated with concomitant clinical signs, like the one located at 50 kDa (OR = 8.2, [2.4-27.7], P = 0.0008) for IgG and (OR = 27.9, [4.2-187.9], P = 0.0006) for IgM. Therefore, the quantitative WB may have application in veterinary diagnostic laboratories to increase the accuracy of the clinical diagnosis of E. cuniculi infection. In addition, this tool may help to further understand the development and function of the humoral immune response to this infectious agent.
MeSH term(s)	Animals ; Blotting, Western/methods ; Blotting, Western/veterinary ; Encephalitozoon cuniculi/immunology ; Encephalitozoon cuniculi/isolation & purification ; Encephalitozoonosis/diagnosis ; Encephalitozoonosis/microbiology ; Encephalitozoonosis/veterinary ; Enzyme-Linked Immunosorbent Assay/veterinary ; Female ; Fluorescent Antibody Technique, Direct/veterinary ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Male ; Rabbits/microbiology
Chemical Substances	Immunoglobulin G ; Immunoglobulin M
Language	English
Publishing date	2017-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-016-5343-4
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Article ; Online: Comparison of an indirect fluorescent antibody test with Western blot for the detection of serum antibodies against Encephalitozoon cuniculi in cats.

Künzel, Frank / Peschke, Roman / Tichy, Alexander / Joachim, Anja

Parasitology research

2014 Volume 113, Issue 12, Page(s) 4457–4462

Abstract: Current clinical research indicates that Encephalitozoon (E.) cuniculi infections in cats may be underdiagnosed, especially in animals with typical ocular signs (cataract/anterior uveitis). Although molecular detection of the pathogen in tissue appears ... ...

Abstract	Current clinical research indicates that Encephalitozoon (E.) cuniculi infections in cats may be underdiagnosed, especially in animals with typical ocular signs (cataract/anterior uveitis). Although molecular detection of the pathogen in tissue appears promising, serology remains the major diagnostic tool in the living animal. While serological tests are established for the main host of E. cuniculi, the rabbit, the routine serological diagnosis for cats still needs validation. The aim of the study was to evaluate the consistency of indirect fluorescence antibody test (IFAT) and Western blot (WB) for the detection of IgG antibodies against E. cuniculi in the serum of 84 cats. In addition, PCR of liquefied lens material or intraocular fluid was performed in those of the cats with a suspected ocular E. cuniculi infection. Twenty-one cats with positive PCR results were considered as a positive reference group. Results obtained by IFAT and WB corresponded in 83/84 serum samples, indicating a very good correlation between both serological methods. Using WB as the standard reference, sensitivity and specificity for the detection of antibodies against E. cuniculi by the IFAT were 97.6 and 100%, respectively. The positive and negative predictive values for the IFAT were 100 and 97.7%, respectively. The accuracy (correct classified proportion) for the detection of IgG antibodies against E. cuniculi in cats was 98.8%. The comparison of both serological methods with the PCR results also revealed a good agreement as 20 out of 21 PCR-positive samples were seropositive both in IFAT and WB. Both tests can be considered as equally reliable assays to detect IgG antibodies against E. cuniculi in cats. As the IFAT is quicker and easier to perform, it is recommended for routine use in the diagnosis of feline encephalitozoonosis.
MeSH term(s)	Animals ; Antibodies, Fungal/blood ; Blotting, Western/standards ; Blotting, Western/veterinary ; Case-Control Studies ; Cat Diseases/diagnosis ; Cat Diseases/immunology ; Cat Diseases/parasitology ; Cats ; Dogs ; Encephalitozoon cuniculi/genetics ; Encephalitozoon cuniculi/immunology ; Encephalitozoon cuniculi/isolation & purification ; Encephalitozoonosis/diagnosis ; Encephalitozoonosis/immunology ; Encephalitozoonosis/veterinary ; Fluorescent Antibody Technique, Indirect/standards ; Fluorescent Antibody Technique, Indirect/veterinary ; Immunoglobulin G/blood ; Madin Darby Canine Kidney Cells ; Rabbits ; Sensitivity and Specificity
Chemical Substances	Antibodies, Fungal ; Immunoglobulin G
Language	English
Publishing date	2014-09-09
Publishing country	Germany
Document type	Comparative Study ; Evaluation Study ; Journal Article
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-014-4130-3
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Book ; Thesis: Moderne Dienstleistungen am Arbeitsmarkt

Peschke, Robert

eine Bestandsaufnahme und kritische Sichtung der Lösungsansätze der Hartz-Kommission

(Rechts-, Wirtschafts- und Sozialwissenschaften)

2005

Abstract: Jeglicher Ansatz rot-grüner Arbeitsmarktreformen seit dem Wahljahr 2002 ist zweifellos verbunden mit dem Namen „Hartz“. Obwohl kaum noch jemand Notiz von den ursprünglichen Lösungsansätzen der Hartz-Kommission nimmt, da diese politisch stark verwaschen ... ...

Author's details	Robert Peschke
Series title	Rechts-, Wirtschafts- und Sozialwissenschaften
Abstract	Jeglicher Ansatz rot-grüner Arbeitsmarktreformen seit dem Wahljahr 2002 ist zweifellos verbunden mit dem Namen „Hartz“. Obwohl kaum noch jemand Notiz von den ursprünglichen Lösungsansätzen der Hartz-Kommission nimmt, da diese politisch stark verwaschen wurden, ist es durchaus sinnvoll, diese kritisch zu diskutieren. Dazu wird der Frage nachgegangen, ob die von der Kommission entwickelten Vorschläge für eine Arbeitsmarktreform überhaupt dazu geeignet waren bzw. wären, Arbeitslosigkeit zu bekämpfen. Es wird dabei unterstellt, dass sämtliche durch die Kommission erarbeiteten Module „eins zu eins“ umgesetzt werden würden. Schließlich zeigt sich, dass die Ansätze der Kommission höchstens ein erster Schritt für mehr Beschäftigung wären. Mit Bezug auf die hier vertretene argumentative Position lässt sich schlussendlich festhalten, dass nach der Hartzschen Arbeitsmarktreform weitere Teile der Sozialsysteme bis hin zum Lohnsetzungssystem, restrukturiert werden müssten. Selbst eine vollständige Umsetzung der ursprünglichen Kommissionsvorschläge hätte das deutsche Arbeitsmarktproblem nicht lösen können.
Keywords	Hartz-Reform ; Arbeitsmarktpolitik ; Reform ; Arbeitsmarktflexibilität ; Wirkungsanalyse ; Deutschland ; Arbeitsmarktreform
Language	German
Size	384 S, graph. Darst, 21 cm
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Zugl.: München, Univ. der Bundeswehr, Diss, 2004
ISBN	3937151419 ; 9783937151410
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Article ; Online: Vector-borne pathogens in clinically healthy military working dogs in eastern Austria.

Sonnberger, Bernhard W / Graf, Barbara / Straubinger, Reinhard K / Rackl, Dietmar / Obwaller, Adelheid G / Peschke, Roman / Shahi Barogh, Bita / Joachim, Anja / Fuehrer, Hans-Peter

Parasitology international

2021 Volume 84, Page(s) 102410

Abstract: Military working dogs have an increased risk of acquiring an infection with vector-borne pathogens due to kennel housing and regular exposure to wildlife and vectors. To evaluate the level of infections in clinically healthy dogs of the Austrian Armed ... ...

Abstract	Military working dogs have an increased risk of acquiring an infection with vector-borne pathogens due to kennel housing and regular exposure to wildlife and vectors. To evaluate the level of infections in clinically healthy dogs of the Austrian Armed Forces, 94 individuals of the Military Working Dog Training Centre (MWDTC) Kaisersteinbruch/eastern Austria were examined in August 2016, February 2019 and August 2019. A modified Knott test was used to determine the presence of microfilariae, PCR for DNA detection of filarioid nematodes (incl. Dirofilaria), Leishmania spp., piroplasms, Borrelia spp., Bartonella spp. and Anaplasmataceae, and serological examination for antibodies against Borrelia burgdoferi s. l. and Leishmania infantum in all dogs. Two dogs were positive for Dirofilaria repens in the Knott test, and one of them also by PCR. Six clinically healthy dogs (4.2%) were positive for Babesia canis (PCR). In serology, 10 (10.6%) of the dogs were positive for specific antibodies against Borrelia burgdoferi s. l. The results suggest that the current measures against arthropod vector exposure and the pathogens they can transmit are not fully sufficient for these dogs. Further investigations of the tick and mosquito fauna in this area will shed more light on the risk of exposure for both the dogs and the staff of the MWDTC.
MeSH term(s)	Animals ; Austria ; Dog Diseases/epidemiology ; Dog Diseases/parasitology ; Dogs ; Prevalence ; Vector Borne Diseases/epidemiology ; Vector Borne Diseases/parasitology ; Vector Borne Diseases/veterinary ; Working Dogs/parasitology
Language	English
Publishing date	2021-06-22
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1363151-2
ISSN	1873-0329 ; 1383-5769
ISSN (online)	1873-0329
ISSN	1383-5769
DOI	10.1016/j.parint.2021.102410
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Book: Zur Pathologie des Sozialstaates

Peschke, Robert

Fehlanreize des Transfersystems, modelliert dargestellt am Beispiel ausgewählter Haushaltsmuster von Ein-Elter-Familien

(Edition Sozialpolitik ; Bd. 3)

2002

Author's details	Robert Peschke
Series title	Edition Sozialpolitik ; Bd. 3
Keywords	Transferzahlung ; Berufstätigkeit ; Einelternfamilie ; Motivation ; Öffentliche Sozialleistungen ; Steuersystem ; Anreiz ; Alleinerziehende ; Arbeitsangebot ; Haushaltsökonomik ; Deutschland
Language	German
Size	80 S, graph. Darst, 21 cm
Document type	Book
Note	Literaturverz. S. 78 - 80
ISBN	3879886776 ; 9783879886777
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