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Article: Open Healing: A Minimally Invasive Protocol with Flapless Ridge Preservation in Implant Patients.

Ionescu, Alecsandru / Dodi, Aliona / Petcu, Lucian Cristian / Nicolescu, Mihnea Ioan

2022 Volume 11, Issue 1

Abstract: We aimed to validate the safety and efficacy of the minimally invasive "open healing" flapless technique for post-extraction socket and alveolar ridge preservation, while assessing the alveolar bone changes. The study enrolled ( ...

Abstract	We aimed to validate the safety and efficacy of the minimally invasive "open healing" flapless technique for post-extraction socket and alveolar ridge preservation, while assessing the alveolar bone changes. The study enrolled (
Language	English
Publishing date	2022-01-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2661517-4
ISSN	2079-7737
ISSN	2079-7737
DOI	10.3390/biology11010142
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Emergency Care for Burn Patients-A Single-Center Report.

Niculae, Andrei / Peride, Ileana / Tiglis, Mirela / Nechita, Ana Maria / Petcu, Lucian Cristian / Neagu, Tiberiu Paul

Journal of personalized medicine

2023 Volume 13, Issue 2

Abstract: Burns, one of the main public health problems, lead to significant mortality and morbidity. Epidemiological studies regarding burn patients in Romania are scarce. The aim of this study is to identify the burn etiology, demographics, clinical ... ...

Abstract	Burns, one of the main public health problems, lead to significant mortality and morbidity. Epidemiological studies regarding burn patients in Romania are scarce. The aim of this study is to identify the burn etiology, demographics, clinical characteristics, and outcomes in patients requiring treatment in a regional burn unit. Design: We performed a retrospective observational study of 2021. Patients: All patients admitted to our six-bed intensive care unit (ICU) were included. Interventions: The following data were collected for further analysis: demographics, burn pattern (etiology, size, depth, affected body region), type of ventilation, ABSI (Abbreviated Burn Severity Index) score, comorbidities, bioumoral parameters, and hospitalization days. Results: There were 93 burned patients included in our study that were divided into two groups: alive patients' group (63.4%) and deceased patients' group (36.6%). The mean age was 55.80 ± 17.16 (SD). There were 65.6% male patients, and 39.8% of the patients were admitted by transfer from another hospital. Further, 59 patients presented third-degree burns, from which 32.3% died. Burns affecting >37% of the total body surface area (TBSA) were noticed in 30 patients. The most vulnerable regions of the body were the trunk ( Conclusion: A thermal factor was responsible for the vast majority of burns, 94.6% of cases being accidents. Extensive and full-thickness burns, burns affecting the arms, inhalation injuries, the need for mechanical ventilation, and a high ABSI score represent important risk factors for mortality. Considering the results, it appears that prompt correction of protein, creatinkinase, and leukocytes levels may contribute to improvement in severe burn patients' outcomes.
Language	English
Publishing date	2023-01-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm13020238
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Article: Open Healing: A Minimally Invasive Protocol with Flapless Ridge Preservation in Implant Patients

Ionescu, Alecsandru / Dodi, Aliona / Petcu, Lucian Cristian / Nicolescu, Mihnea Ioan

Biology. 2022 Jan. 14, v. 11, no. 1

2022

Abstract: We aimed to validate the safety and efficacy of the minimally invasive “open healing” flapless technique for post-extraction socket and alveolar ridge preservation, while assessing the alveolar bone changes. The study enrolled (n = 104) patients (0.55 ... ...

Abstract	We aimed to validate the safety and efficacy of the minimally invasive “open healing” flapless technique for post-extraction socket and alveolar ridge preservation, while assessing the alveolar bone changes. The study enrolled (n = 104) patients (0.55 sex ratio), with atraumatic extraction of (N = 135) hopeless teeth, followed by either immediate placement of tissue level implants (N₁ = 26), or later stage implant insertion (N₂ = 109). No flap was raised in either situation. Post-extraction sockets were filled with deproteinized bovine bone granules and covered by collagen resorbable membrane—left purposely exposed during healing. This yielded an uneventful healing, with sufficient bone formation, while avoiding soft-tissue problems. The need for additional augmentation was assessed clinically and by calibrated CBCT scans at six months, before either loading (N₁) or implant insertion (N₂). Implant success and survival rate were evaluated at 12-, 24-, and 60-month follow-up control sessions. The inserted implants had a survival rate of 98.5% and a success rate of 94.8% at five-year follow-up. Open healing technique with flapless approach can be favorable for preserving the 3D architecture of the post-extraction socket, as well as the alveolar ridge width and height.
Keywords	bone formation ; cattle ; collagen ; sex ratio ; survival rate
Language	English
Dates of publication	2022-0114
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2661517-4
ISSN	2079-7737
ISSN	2079-7737
DOI	10.3390/biology11010142
Database	NAL-Catalogue (AGRICOLA)

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Article: Epidemiological Characteristics and Mortality Risk Factors Comparison in Dialysis and Non-Dialysis CKD Patients with COVID-19-A Single Center Experience.

Niculae, Andrei / Peride, Ileana / Nechita, Ana-Maria / Petcu, Lucian Cristian / Tiglis, Mirela / Checherita, Ionel Alexandru

Journal of personalized medicine

2022 Volume 12, Issue 6

Abstract: 1) Background: Despite some controversies between studies, chronic kidney disease (CKD) has a negative impact on COVID-19 outcomes, with patients presenting a higher mortality risk than in the general population. Studies have shown an association ... ...

Abstract	(1) Background: Despite some controversies between studies, chronic kidney disease (CKD) has a negative impact on COVID-19 outcomes, with patients presenting a higher mortality risk than in the general population. Studies have shown an association between COVID-19 severe cases and different inflammatory biomarkers. The aim of this study was to emphasize the epidemiological characteristics of CKD patients diagnosed with COVID-19 and to determine if the risk of mortality, and the severity of this infection might be influenced by different parameters. (2) Methods: Our retrospective study included CKD patients with COVID-19—362 in the non-dialysis group and 132 in the dialysis group. (3) Results: There were significant statistical differences between our groups regarding age (p < 0.001), hemoglobin (p < 0.001), interleukin-6 (p < 0.001), serum albumin (p = 0.016), procalcitonin (p = 0.002), ferritin (p < 0.001), and of course serum creatinine (p < 0.001). Even if the risk of death was higher in the dialysis group (Exp(b) = 1.839), the survival proportions were similar in both groups. (4) Conclusions: High values of hemoglobin, serum creatinine, and LDH at admission, age, length of hospital stay ≤ 10 days, and a pulmonary impairment > 25% are responsible for an adverse outcome in non-dialysis and dialysis patients diagnosed with COVID-19.
Language	English
Publishing date	2022-06-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm12060966
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Article: Utility of sFtl-1 and Placental Growth Factor Ratio for Adequate Preeclampsia Management.

Ciciu, Elena / Paṣatu-Cornea, Ana-Maria / Dumitru, Stefania / Petcu, Lucian Cristian / Salim, Camer / Tuta, Liliana-Ana

Healthcare (Basel, Switzerland)

2023 Volume 11, Issue 3

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2023-01-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare11030381
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Article: Schwannoma: A Rare Case of Submucosal Gastric Tumor.

Fugărețu, Cosmina / Mișarca, Cătalin / Petcu, Lucian / Șoană, Raluca / Cîrnațiu, Andrada / Surlin, Marin Valeriu / Patrascu, Stefan / Ramboiu, Sandu

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 12

Abstract: Schwannoma is a tumor that originates from the Schwann cells that surround a neuron's axon. This tumor is very rare in the gastrointestinal tract and develops submucosally from intestinal nerve plexuses. The most common location for gastrointestinal ... ...

Abstract	Schwannoma is a tumor that originates from the Schwann cells that surround a neuron's axon. This tumor is very rare in the gastrointestinal tract and develops submucosally from intestinal nerve plexuses. The most common location for gastrointestinal schwannomas is the stomach, where they account for only 0.2% of gastric tumors. We present the case of a 56-year-old asymptomatic patient who was diagnosed, following a routine ultrasound examination, with an abdominal tumor. An abdominal MRI confirmed the gastric origin of the tumor. Although a subsequent upper-digestive endoscopic ultrasound was performed, a definitive diagnosis could not be established. Thus, a laparoscopic wedge resection of the stomach was performed. The immunohistochemical examination of the tumor established the diagnosis of benign schwannoma. Despite the availability of advanced endoscopy and imaging techniques, the diagnosis of gastric schwannoma is very rarely preoperative. The immunohistochemical identification of S-100 on the surgical specimen confirmed the diagnosis.
Language	English
Publishing date	2023-06-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13122073
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Article ; Online: Evaluation of Total Hip Arthroplasty Performed from a Lateral Approach as Optimal Treatment for Femoral Neck Fractures in Elderly, Active Patients.

Obada, Bogdan / Iliescu, Dan-Marcel / Georgeanu, Vlad-Alexandru / Petcu, Lucian Cristian / Iliescu, Madalina Gabriela / Popescu, Ion-Andrei

Ortopedia, traumatologia, rehabilitacja

2023 Volume 25, Issue 3, Page(s) 131–141

Abstract: Background: The aim of the study was to evaluate total hip arthroplasty in terms of clinical and functional outcomes, rate of complications and hospitalization, as a treatment of choice for displaced femoral neck fractures.: Materials and methods: We ...

Abstract	Background: The aim of the study was to evaluate total hip arthroplasty in terms of clinical and functional outcomes, rate of complications and hospitalization, as a treatment of choice for displaced femoral neck fractures. Materials and methods: We retrospectively reviewed the data of 526 patients with THA operated on in our department between January 2017 and December 2021. Clinical examinations, functional outcome assessment and radiographic evaluation were performed during follow-up. Patients were evaluated at the following time points: postoperatively at 3 days, 6 weeks, 12 weeks and 1 year, and we recorded surgery related data, complications, Visual Analogue Scale pain score, Harris Hip Score, the Western Ontario McMaster Osteoarthritis Index, and range of motion. Results: Low intraoperative blood loss, short surgical time, short hospitalization, early mobilization of the patient and a good range of motion testify that the modified direct lateral approach is a valuable procedure for the patients with THA. A VAS score evaluated at 3 days and 6 weeks indicated a very good overall postoperative experience. The HHS and Womac scores were evaluated at 6 weeks, 12 weeks and 1 year and showed excellent results. Conclusion: THA for active patients with a displaced fracture of the femoral neck is an excellent treatment option which provides lasting pain relief, a high level of function and very low rates of reoperation.
MeSH term(s)	Humans ; Aged ; Arthroplasty, Replacement, Hip/methods ; Retrospective Studies ; Treatment Outcome ; Femoral Neck Fractures/surgery ; Pain
Language	English
Publishing date	2023-12-11
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2205282-3
ISSN	2084-4336 ; 1509-3492
ISSN (online)	2084-4336
ISSN	1509-3492
DOI	10.5604/01.3001.0053.7975
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Article ; Online: The Most Frequent Neurological Complications in HIV Patients in Constanta and the Influence that Coinfections Have in the Onset of Such Conditions

Corina Pascu / Magdalena Dumitru Irina / Carmen Cernat Roxana / Cristian Petcu Lucian / Sorin Rugina

ARS Medica Tomitana, Vol 26, Iss 3, Pp 131-

2020 Volume 136

Abstract: Abstract: This paper shows the results of a retrospective observational analytical study that has enrolled 166 HIV positive patients diagnosed with a neurological complication between June 2012 and June 2020, in Clinical Infectious Diseases Hospital of ... ...

Abstract	Abstract: This paper shows the results of a retrospective observational analytical study that has enrolled 166 HIV positive patients diagnosed with a neurological complication between June 2012 and June 2020, in Clinical Infectious Diseases Hospital of Constanta. 119 patients (71,69%) were diagnosed with one of the three neurological complications: HIV associated dementia (HAD), Progressive Multifocal Leukoencephalopathy (PML) and CNS Toxoplasmosis (CT). We have noted CD4 levels, viral loads, and the presence/absence of other infections like: HBV, HCV, Treponema pallidum, Mycobacterium Tuberculosis.
Keywords	hiv ; coinfections ; hiv associated dementia ; progressive multifocal leukoencephalopathy ; cns toxoplasmosis ; Medicine ; R
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Sciendo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Efficiency of the Fight Against HIV, in Constanta, from the Perspective of Neurological Complications

Corina Pascu / Magdalena Dumitru Irina / Carmen Cernat Roxana / Cristian Petcu Lucian / Sorin Rugina

ARS Medica Tomitana, Vol 26, Iss 3, Pp 126-

2020 Volume 130

Abstract: In order to control and end the AIDS epidemic, we all need to hit the 0-0-0 target. That means 0 HIV infections, 0 mortality caused by AIDS and 0 discrimination. We performed a retrospective observational analytical study on 166 HIV positive patients ... ...

Abstract	In order to control and end the AIDS epidemic, we all need to hit the 0-0-0 target. That means 0 HIV infections, 0 mortality caused by AIDS and 0 discrimination. We performed a retrospective observational analytical study on 166 HIV positive patients with a neurological complication, diagnosed between June 2012 and June 2020, in Clinical Infectious Diseases Hospital of Constanta. We collected data from the observational charts that revealed if the patient was known with HIV infection at the time of the neurological complication diagnosis, information about the treatment (how many treatment regimens, classes of antiretroviral drugs, CNS Penetration-Effectiveness Rank), treatment compliance. The patients were divided into two groups: first group “opportunistic infections (OI)” and second group “other neurological conditions (ONC)”. 16 patients (9,6%) have the neurological condition as first manifestation of HIV infection. Opportunistic infections, correlated with a poor immunological status continue to have a high percentage (46,98%) of neurological complications, being associated with a poor treatment compliance (p<0,001). Integrase inhibitors were associated, in this study, more with opportunistic infections and less with other neurological conditions (OR=2,885; 95% IC), this finding needs further research. Long term survivors have problems with treatment compliance manifesting treatment fatigue, even if they have treatment regimens with good CNS penetrability. Poor compliance is associated with high risk of opportunistic infections and opportunistic infections have a higher mortality than other neurological complications. Our task for the future is to find ways to improve treatment adherence in order for HIV patients to have a better and longer life.
Keywords	hiv ; neurological complication ; compliance ; integrase inhibitors ; mortality ; Medicine ; R
Subject code	616
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Sciendo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Sustainability of balneal tourism in pre- and post-pandemic period

Oprea Carmen / Ionescu Elena Valentina / Matei Raluca / Sorici Costin Octavian / Salceanu Claudia / Jeflea Victor / Pazara Loredana / Ungureanu Adelina Elena / Petcu Lucian / Tucmeanu Elena-Roxana / Iliescu Mădălina Gabriela

Balneo and PRM Research Journal, Vol 14, Iss 3, p

2023 Volume 580

Abstract: The scope of the present study was to evaluate the results obtained from implementing the integrated programme of sustainable entrepreneurship specific to balneal tourism in the pre- and post-pandemic period at the Balneal and Rehabilitation Sanatorium ... ...

Abstract	The scope of the present study was to evaluate the results obtained from implementing the integrated programme of sustainable entrepreneurship specific to balneal tourism in the pre- and post-pandemic period at the Balneal and Rehabilitation Sanatorium of Techirghiol (SBRT), with the identification of current trends and preferences of the population regarding healthcare services in the Techirghiol area. Methods: The retrospective longitudinal study, conducted from 2018 to 2022, used data gathered in SBRT services on a number of patients grouped by condition, the quality of therapeutic water accessed by patients and of waste water discharged into the lake, books and documents specific to the proposed topic. Results: Starting with the pandemic year 2020, patients are also referred to SBRT for treatment of post covid after-effects (restrictive/obstructive respiratory diseases). Water waste discharged into Lake Techirghiol in 2020 exceeds the legal limits for the arithmetic mean values of nitrogen ammonia, returning to normal in 2021 (2.88 mg/l), reaching 0.24mg/l in 2022. Considering the 2020 pandemic year as the reference year, the number of tourists in 2020 decreased by 58% compared to 2018 and by 37% compared to 2019, with an increase of 42% and 43% in 2021 and 2022 respectively. Conclusions: The number of patients accessing natural factor therapies in the time period analysed has seen a steady post-pandemic increase. The sustainable development of spa tourism in the Techirghiol area requires an integrative approach that ensures environmental protection.
Keywords	techirghiol area (romania) ; techirghiol lake ; balneal tourism ; patients ; Science ; Q
Subject code	910
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	Romanian Association of Balneology, Editura Balneara
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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