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  1. Article ; Online: Mycobacterium abscessus

    Chow, Ivy / Chan, Sara / Lin, Molly / Peters, Laurenna

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2023  Volume 195, Issue 42, Page(s) E1440–E1442

    MeSH term(s) Humans ; Mycobacterium abscessus ; Scalp ; Mycobacterium Infections, Nontuberculous/diagnosis ; Mycobacterium Infections, Nontuberculous/drug therapy ; Mycobacterium Infections, Nontuberculous/etiology ; Central America ; Hair ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-10-30
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.230794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.136: Show issues Location:
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  2. Article ; Online: [No title information]

    Chow, Ivy / Chan, Sara / Lin, Molly / Peters, Laurenna

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2023  Volume 195, Issue 49, Page(s) E1731–E1734

    Title translation Infection du cuir chevelu à
    MeSH term(s) Humans ; Mycobacterium abscessus ; Scalp ; Central America ; Skin Transplantation ; Hair
    Language French
    Publishing date 2023-12-17
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.230794-f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.136: Show issues Location:
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  3. Article ; Online: Secondary Strongyloides stercoralis prophylaxis in patients with human T-cell lymphotropic virus type 1 infection: report of two cases.

    Peters, Laurenna / McCarthy, Anne E / Faught, Carolyn

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2009  Volume 13, Issue 6, Page(s) e501–3

    Abstract: Secondary ivermectin prophylaxis for strongyloidiasis in two patients with human T-cell lymphotropic virus type 1 (HTLV-1)-associated malignancies and fully treated complicated strongyloidiasis is described. Treatment was well tolerated and neither ... ...

    Abstract Secondary ivermectin prophylaxis for strongyloidiasis in two patients with human T-cell lymphotropic virus type 1 (HTLV-1)-associated malignancies and fully treated complicated strongyloidiasis is described. Treatment was well tolerated and neither patient developed further manifestations of hyperinfection. As treatment failure for complicated strongyloidiasis has been documented in severely immunosuppressed patients, secondary prophylaxis may be indicated.
    MeSH term(s) Adult ; Animals ; Antinematodal Agents/therapeutic use ; Chemoprevention ; Fatal Outcome ; Female ; HTLV-I Infections/complications ; Human T-lymphotropic virus 1/isolation & purification ; Humans ; Ivermectin/therapeutic use ; Leukemia, T-Cell/complications ; Lymphoma, Non-Hodgkin/complications ; Male ; Strongyloides stercoralis/drug effects ; Strongyloides stercoralis/isolation & purification ; Strongyloidiasis/complications ; Strongyloidiasis/parasitology ; Strongyloidiasis/prevention & control
    Chemical Substances Antinematodal Agents ; Ivermectin (70288-86-7)
    Language English
    Publishing date 2009-11
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2009.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4516: Show issues Location:
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  4. Article ; Online: Usefulness of Interferon-γ release assays in the diagnosis of erythema induratum.

    Vera-Kellet, Cristián / Peters, Laurenna / Elwood, Kevin / Dutz, Jan P

    Archives of dermatology

    2011  Volume 147, Issue 8, Page(s) 949–952

    Abstract: Background: Erythema induratum (EI) manifests as tender indurated nodules on the lower legs. It may be associated with concomitant active tuberculosis (TB) and is considered a hypersensitivity reaction to mycobacterial antigens. However, the results of ... ...

    Abstract Background: Erythema induratum (EI) manifests as tender indurated nodules on the lower legs. It may be associated with concomitant active tuberculosis (TB) and is considered a hypersensitivity reaction to mycobacterial antigens. However, the results of Mycobacterium cultures are rarely positive, and the tuberculin skin test is of limited usefulness in populations exposed to bacille Calmette-Guérin (BCG). Interferon-γ release assays (IGRAs) are alternatives to the tuberculin skin test and have high specificity. We explored the use of IGRAs as an adjunct in the diagnosis of EI. We describe 5 patients with positive tuberculin skin test results and a history of vaccination against BCG or TB in whom IGRAs supported the diagnosis of EI.
    Observations: All patients were initially seen with tender nodules on the lower legs and a history of BCG vaccination or TB. Tuberculin skin test results were positive, and chest radiographic results were normal. The results of Mycobacterium cultures were negative in all patients, and biopsy specimens were compatible with EI. Interferon-γ release assays were performed in all patients and supported initiation of anti-TB treatment in 4 of 5 patients. Conclusion  Interferon-γ release assays may have value as an adjunct in the diagnosis of EI, particularly in the setting of prior BCG exposure.
    MeSH term(s) Adult ; Erythema Induratum/diagnosis ; Erythema Induratum/immunology ; Female ; Humans ; Interferon-gamma/analysis ; Middle Aged
    Chemical Substances Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2011-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 212139-6
    ISSN 1538-3652 ; 0003-987X
    ISSN (online) 1538-3652
    ISSN 0003-987X
    DOI 10.1001/archdermatol.2011.183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A brief tool to assess capacity to consent for medical care among homeless individuals with problematic substance use: study protocol.

    Taylor, Darlene / Masse, Louise / Ho, Anita / Rekart, Michael L / Tyndall, Mark / Henry, Bonnie / Clifton, Joanne / Peters, Laurenna / Ogilvie, Gina / Buxton, Jane

    Archives of public health = Archives belges de sante publique

    2013  Volume 71, Issue 1, Page(s) 11

    Abstract: Background: Public health care increasingly uses outreach models to engage individuals who are marginalized, many of whom misuse substances. Problematic substance use, together with marginalization from the health care system, among homeless adults ... ...

    Abstract Background: Public health care increasingly uses outreach models to engage individuals who are marginalized, many of whom misuse substances. Problematic substance use, together with marginalization from the health care system, among homeless adults makes it difficult to assess their capacity to consent to medical care. Tools have been developed to assess capacity to consent; however, these tools are lengthy and unsuitable for outreach settings. The primary objective of this study is to develop, validate, and pilot a brief but sensitive screening instrument which can be used to guide clinicians in assessing capacity to consent in outreach settings. The goal of this paper is to outline the protocol for the development of such a tool.
    Methods/design: A brief assessment tool will be developed and compared to the MacArthur Competency Assessment Tool for Treatment (MacCAT-T). As list of 36 possible questions will be created by using qualitative data from clinician interviews, as well as concepts from the literature. This list will be rated by content experts according to the extent that it corresponds to the test objectives. The instrument will be validated with 300 homeless adult volunteers who self-report problematic substance use. Participants will be assessed for capacity using the MacCAT-T and the new instrument. A combination of Classical Test Theory and advanced psychometric methods will be used for the psychometric analysis. Corrected Item-Total correlation will be examined to identify items that discriminate poorly. Guided exploratory factor analysis will be conducted on the final selection of items to confirm the assumptions for a unidimensional polytomous Rasch model. If unidimensionality is confirmed, an unstandardized Cronbach Alpha will be calculated. If multi-dimensionality is detected, a multidimensional Rasch analysis will be conducted. Results from the new instrument will be compared to the total score from the MacCAT-T by using Pearson's correlation test. The new instrument will then be piloted in real-time by street outreach clinicians to determine the acceptability and usefulness of the new instrument.
    Discussion: This research will build on the existing knowledge about assessing capacity to consent and will contribute new knowledge about assessing individuals whose judgment is impaired by substance use.
    Language English
    Publishing date 2013-05-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1117688-x
    ISSN 2049-3258 ; 0778-7367 ; 0003-9578
    ISSN (online) 2049-3258
    ISSN 0778-7367 ; 0003-9578
    DOI 10.1186/0778-7367-71-11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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