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  1. Article: PlantMolecularTasteDB: A Database of Taste Active Phytochemicals.

    Gradinaru, Teodora-Cristiana / Petran, Madalina / Dragos, Dorin / Gilca, Marilena

    Frontiers in pharmacology

    2022  Volume 12, Page(s) 751712

    Language English
    Publishing date 2022-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.751712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Phytochemicals and Inflammation: Is Bitter Better?

    Dragoș, Dorin / Petran, Madalina / Gradinaru, Teodora-Cristiana / Gilca, Marilena

    Plants (Basel, Switzerland)

    2022  Volume 11, Issue 21

    Abstract: The taste of a herb influences its use in traditional medicine. A molecular basis for the taste-based patterns ruling the distribution of herbal (ethno) pharmacological activities may not be excluded. This study investigated the potential correlations ... ...

    Abstract The taste of a herb influences its use in traditional medicine. A molecular basis for the taste-based patterns ruling the distribution of herbal (ethno) pharmacological activities may not be excluded. This study investigated the potential correlations between the anti-inflammatory activity (AIA) and the phytocompound taste and/or its chemical class. The study relies on information gathered by an extensive literature (articles, books, databases) search and made public as PlantMolecularTasteDB. Out of a total of 1527 phytotastants with reliably documented taste and structure available in PlantMolecularTasteDB, 592 (for each of which at least 40 hits were found on PubMed searches) were included in the statistical analysis. A list of 1836 putative molecular targets of these phytotastants was afterwards generated with SwissTargetPrediction tool. These targets were systematically evaluated for their potential role in inflammation using an international databases search. The correlations between phytochemical taste and AIA, between chemical class and AIA, and between the taste and the number of inflammation related targets were statistically analyzed. Phytochemical taste may be a better predictor of AIA than the chemical class. Bitter phytocompounds have a higher probability of exerting AIA when compared with otherwise phytotastants. Moreover, bitter phytotastants act upon more inflammation related targets than non-bitter tasting compounds.
    Language English
    Publishing date 2022-11-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants11212991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Historical ethnobotanical review of medicinal plants used to treat children diseases in Romania (1860s-1970s).

    Petran, Madalina / Dragos, Dorin / Gilca, Marilena

    Journal of ethnobiology and ethnomedicine

    2020  Volume 16, Issue 1, Page(s) 15

    Abstract: Background: Romanian ethnopediatrics has a long history of medicinal plant use. The main objective of the present review was to identify, collect, systematize, and prioritize the available bibliographical data related to medicinal plants traditionally ... ...

    Abstract Background: Romanian ethnopediatrics has a long history of medicinal plant use. The main objective of the present review was to identify, collect, systematize, and prioritize the available bibliographical data related to medicinal plants traditionally used to treat various pediatric diseases in Romania during the 1860s-1970s.
    Methods: Information was mainly obtained by manual systematic search in various relevant historical works focused on the traditional use of medicinal plants in Romania (1860s-1970s), found in the Archives of Romanian Academy Library and National Romanian Library.
    Results: A total of 153 medicinal plants belonging to 52 families were identified as having ethnopediatric significance. The plant traditional indications, targeted body systems, parts used, and way of administration were provided. We have also proposed one index (expressed as percentage) in order to assess the ethnopediatric applicability area of species: ethnopediatric relative therapeutic versatility (ERTV), which was calculated on the basis of the number of distinct uses mentioned for a species. The species identified to have the highest ERTV scores were Dryopteris filix-mas (100%), Gratiola officinalis (85.71%), Allium sativum (71.42%), Eryngium planum (71.42%), Juglans regia (71.42%), Matricaria chamomilla (71.42%), Plantago major (71.42%).
    Conclusions: The present study exposed for the first time to the international scientific community important ethnopediatric information contained in several local Romanian bibliographical resources that could guide the local and international researchers towards new directions of plant valorization.
    MeSH term(s) Child ; Ethnopharmacology/history ; History, 19th Century ; History, 20th Century ; Humans ; Medicine, Traditional ; Pediatrics ; Phytotherapy/history ; Plants, Medicinal/chemistry ; Romania
    Language English
    Publishing date 2020-03-24
    Publishing country England
    Document type Historical Article ; Journal Article ; Review
    ISSN 1746-4269
    ISSN (online) 1746-4269
    DOI 10.1186/s13002-020-00364-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Historical ethnobotanical review of medicinal plants used to treat children diseases in Romania (1860s–1970s)

    Petran, Madalina / Dragos, Dorin / Gilca, Marilena

    Journal of ethnobiology and ethnomedicine. 2020 Dec., v. 16, no. 1

    2020  

    Abstract: BACKGROUND: Romanian ethnopediatrics has a long history of medicinal plant use. The main objective of the present review was to identify, collect, systematize, and prioritize the available bibliographical data related to medicinal plants traditionally ... ...

    Abstract BACKGROUND: Romanian ethnopediatrics has a long history of medicinal plant use. The main objective of the present review was to identify, collect, systematize, and prioritize the available bibliographical data related to medicinal plants traditionally used to treat various pediatric diseases in Romania during the 1860s–1970s. METHODS: Information was mainly obtained by manual systematic search in various relevant historical works focused on the traditional use of medicinal plants in Romania (1860s–1970s), found in the Archives of Romanian Academy Library and National Romanian Library. RESULTS: A total of 153 medicinal plants belonging to 52 families were identified as having ethnopediatric significance. The plant traditional indications, targeted body systems, parts used, and way of administration were provided. We have also proposed one index (expressed as percentage) in order to assess the ethnopediatric applicability area of species: ethnopediatric relative therapeutic versatility (ERTV), which was calculated on the basis of the number of distinct uses mentioned for a species. The species identified to have the highest ERTV scores were Dryopteris filix-mas (100%), Gratiola officinalis (85.71%), Allium sativum (71.42%), Eryngium planum (71.42%), Juglans regia (71.42%), Matricaria chamomilla (71.42%), Plantago major (71.42%). CONCLUSIONS: The present study exposed for the first time to the international scientific community important ethnopediatric information contained in several local Romanian bibliographical resources that could guide the local and international researchers towards new directions of plant valorization.
    Keywords Allium sativum ; Dryopteris filix-mas ; Eryngium planum ; Gratiola officinalis ; Juglans regia ; Matricaria chamomilla ; Plantago major ; area ; children ; ethnobotany ; history ; information ; medicinal plants ; researchers ; therapeutics ; traditional medicine ; Romania
    Language English
    Dates of publication 2020-12
    Size p. 15.
    Publishing place BioMed Central
    Document type Article
    Note NAL-light ; Review
    ISSN 1746-4269
    DOI 10.1186/s13002-020-00364-6
    Database NAL-Catalogue (AGRICOLA)

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  5. Book ; Online: Strangeness and charm in quark-gluon hadronization

    Petran, Michal

    2013  

    Abstract: This dissertation presents a theoretical study of soft hadron production in relativistic heavy-ion collisions. We explore the principles governing the hadronization of the expanding QGP fireball, and to understand its properties. Much of the ongoing ... ...

    Abstract This dissertation presents a theoretical study of soft hadron production in relativistic heavy-ion collisions. We explore the principles governing the hadronization of the expanding QGP fireball, and to understand its properties. Much of the ongoing effort is to demonstrate the validity of a QGP hadronization model which describes the particle production data accurately. We begin with a centrality study of multistrange hadrons from Au-Au collisions at 62.4 GeV at RHIC. We show that the statistical hadronization model (SHM) well describes particle production in QGP hadronization. For all centralities, the physical properties are compatible with the earlier proposed critical hadronization pressure suggesting universal hadronization conditions of QGP. Heavy-ion collisions at LHC present a new challenge for SHM in describing particle production at TeV energy scales. We show that the chemical non-equilibrium model gives a good description of the hadron production in Pb--Pb collisions at 2.76 TeV consistently as a function of centrality. Moreover, the model parameters assume expected values suggested by previous studies at lower energies. The quark-gluon plasma fireball hadronizes at the same universal hadronization conditions, that is a common critical pressure, entropy and energy density. At LHC energies, a significant amount of charm is expected to be produced and it is therefore crucial to incorporate charm into the present description of particle production. We present an upgraded SHARE with CHARM program, that quantifies the effect of charm on the yield of lighter hadrons and physical properties of the hadronizing fireball. In addition to light flavors ($u,d,s$), SHARE with CHARM describes charm hadron production and decays. We observe, that according to present experimental results, charm decays mainly affect the yields of multistrange particles.

    Comment: 143 pages
    Keywords High Energy Physics - Phenomenology ; Nuclear Theory
    Subject code 660
    Publishing date 2013-11-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Controversial Flow Cytometry Monitoring of a Relapse Case of Pediatric T Cell Acute Lymphoblastic Leukemia: A Case Report.

    Popa, Delia Codruţa / Şerbănică, Andreea / Obrisca, Radu / Şerbănică, Ionut / Radu, Letiţia / Jercan, Cristina / Marcu, Andra / Bica, Ana / Asan, Minodora / Petran, Mădălina / Dragomir, Mihaela / Jardan, Cerasela / Ţică, Valeria / Gheorghe, Anca / Stoian, Irina / Coriu, Daniel / Coliţă, Anca / Coliţă, Andrei

    Frontiers in medicine

    2022  Volume 9, Page(s) 858809

    Abstract: Acute lymphoblastic leukemia (ALL) is the most frequent childhood cancer, with 80-85% represented by B cell ALL and only 15% by T cell ALL. T Cell ALL (T-ALL) carries a more reserved prognosis compared to B Cell ALL (B-ALL) with regard to response to ... ...

    Abstract Acute lymphoblastic leukemia (ALL) is the most frequent childhood cancer, with 80-85% represented by B cell ALL and only 15% by T cell ALL. T Cell ALL (T-ALL) carries a more reserved prognosis compared to B Cell ALL (B-ALL) with regard to response to treatment, risk of relapse, and overall survival. Progress made in current monitoring protocols such as
    Language English
    Publishing date 2022-03-22
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.858809
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Observaţii radiologice în relaţie cu expunerea profesională la carbura de siliciu (SiC).

    Petran, M / Cocârlă, A

    Pneumologia (Bucharest, Romania)

    1999  Volume 48, Issue 4, Page(s) 297–300

    Abstract: There have been investigated radiologically 191 workers from a SiC factory, exposed to dust concentrations exceeding largely that TLV and with a content of non-reactive SiO2 less than 1%. Radiological examinations were performed systematically at a three ...

    Title translation Radiological observations in relation to occupational exposure to silicon carbide (SiC).
    Abstract There have been investigated radiologically 191 workers from a SiC factory, exposed to dust concentrations exceeding largely that TLV and with a content of non-reactive SiO2 less than 1%. Radiological examinations were performed systematically at a three years interval, beginning with 1988. Radiology interpreting was performed according to ILO 1980 classification for persistent radiological opacities due to mineral dusts. Our results sustain the idea of the pneumoconiogen potential of SiC: there is a high prevalence of radiological findings (16.2%) and the opacities have an extend from 2 to 6 areas and the profusion from 0/1 to 2/2.
    MeSH term(s) Air Pollutants, Occupational/adverse effects ; Biocompatible Materials/adverse effects ; Carbon Compounds, Inorganic/adverse effects ; Dust/adverse effects ; Female ; Humans ; Incidence ; Lung/diagnostic imaging ; Male ; Occupational Exposure/adverse effects ; Particle Size ; Pneumoconiosis/diagnostic imaging ; Pneumoconiosis/epidemiology ; Pneumoconiosis/etiology ; Prevalence ; Radiography ; Romania/epidemiology ; Sex Distribution ; Silicon Compounds/adverse effects
    Chemical Substances Air Pollutants, Occupational ; Biocompatible Materials ; Carbon Compounds, Inorganic ; Dust ; Silicon Compounds ; silicon carbide (WXQ6E537EW)
    Language Romanian
    Publishing date 1999-10
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2064988-5
    ISSN 2247-059X ; 2067-2993 ; 1223-3056
    ISSN (online) 2247-059X
    ISSN 2067-2993 ; 1223-3056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  8. Article: Zákonné jednotky velicin vyskytujících se nejcastĕji v lékarských vĕdách.

    Petrán, M

    Ceskoslovenska fysiologie

    1978  Volume 27, Issue 5, Page(s) 387–399

    Title translation Legal units of measurement occuring most often in medical science.
    MeSH term(s) International System of Units ; Weights and Measures
    Language Czech
    Publishing date 1978-09
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 419220-5
    ISSN 1210-6313 ; 0009-0557
    ISSN 1210-6313 ; 0009-0557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 208: Show issues Location:
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  9. Article: Association between bronchial hyper-reactivity and exposure to silicon carbide.

    Petran, M / Cocârlă, A / Băiescu, M

    Occupational medicine (Oxford, England)

    2000  Volume 50, Issue 2, Page(s) 103–106

    Abstract: A clinical study of 191 workers in the silicon carbide production industry was carried out in order to determine the prevalence of respiratory symptoms (wheezing, dyspnoea and breathlessness after exercise). Such symptoms occurred in 50 (26.1%) subjects, ...

    Abstract A clinical study of 191 workers in the silicon carbide production industry was carried out in order to determine the prevalence of respiratory symptoms (wheezing, dyspnoea and breathlessness after exercise). Such symptoms occurred in 50 (26.1%) subjects, of whom 24 accepted testing for bronchial reactivity. Of these 24, 19 (79.2%) were positive. These findings suggest that exposure to SiC may be associated with bronchial hyper-reactivity. Positive results were more frequent in women than in men, while differences between smokers and non-smokers were insignificant, a phenomenon that has often been noted in persons exposed to massive risk.
    MeSH term(s) Adult ; Air Pollutants, Occupational/adverse effects ; Biocompatible Materials/adverse effects ; Bronchial Hyperreactivity/chemically induced ; Bronchial Hyperreactivity/epidemiology ; Carbon Compounds, Inorganic/adverse effects ; Cohort Studies ; Cross-Sectional Studies ; Dust/adverse effects ; Female ; Forced Expiratory Volume/physiology ; Humans ; Male ; Occupational Exposure/adverse effects ; Prevalence ; Risk Factors ; Romania/epidemiology ; Silicon Compounds/adverse effects ; Smoking/adverse effects
    Chemical Substances Air Pollutants, Occupational ; Biocompatible Materials ; Carbon Compounds, Inorganic ; Dust ; Silicon Compounds ; silicon carbide (WXQ6E537EW)
    Language English
    Publishing date 2000-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1103950-4
    ISSN 1471-8405 ; 0962-7480
    ISSN (online) 1471-8405
    ISSN 0962-7480
    DOI 10.1093/occmed/50.2.103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Tandem scanning microscope--a new tool for three-dimensional microanatomy.

    Petrán, M / Hadravský, M

    Progress in clinical and biological research

    1989  Volume 295, Page(s) 551–558

    Abstract: Tandem Scanning Microscope enables us to observe in real time one thin layer under the surface of a highly complex semitransparent object (e. g. living tissue), make photographs of thick layers in such objects and observe (by means of a stereoscope) ... ...

    Abstract Tandem Scanning Microscope enables us to observe in real time one thin layer under the surface of a highly complex semitransparent object (e. g. living tissue), make photographs of thick layers in such objects and observe (by means of a stereoscope) three dimensional images of such objects. Important results can be obtained with moderate expenditure on basic hardware and the equipment can be expanded steadily according to the state of our budget.
    MeSH term(s) Anatomy/methods ; Animals ; Humans ; Microscopy, Electron, Scanning/instrumentation ; Microscopy, Electron, Scanning/methods ; Models, Anatomic ; Photography
    Language English
    Publishing date 1989
    Publishing country United States
    Document type Journal Article
    ISSN 0361-7742
    ISSN 0361-7742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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