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Article: Dermal Substitutes and Skin Grafts in the Reconstruction of Post-Traumatic Total Scalp Avulsion: A Case Series.

Petrocelli, Marzia / Togo, Giulia / Ricci, Silvia / Zeneli, Flavia / Cutrupi, Sebastiano / Baietti, Annamaria / Bonavolontà, Paola / Califano, Luigi / Vaira, Luigi Angelo / Scarpa, Alfonso / Di Stadio, Arianna / Salzano, Giovanni

Journal of clinical medicine

2023 Volume 12, Issue 6

Abstract: Although scalp defects can vary in size and thickness, scalp avulsion represents a rare occurrence. This type of lesion may have different origins, but it is usually related to long hair being caught in agricultural machinery. The management of full- ... ...

Abstract	Although scalp defects can vary in size and thickness, scalp avulsion represents a rare occurrence. This type of lesion may have different origins, but it is usually related to long hair being caught in agricultural machinery. The management of full-thickness scalp defects poses a challenge to the head and neck surgeon due to the possible involvement of neurovascular structures and scar retraction, which can affect the esthetic restoration of the area. Several algorithms for the choice of scalp reconstruction have been proposed in the literature and different techniques are available for extensive scalp defect reconstruction (local soft tissue flap, microvascular free flap, and skin graft combined with dermal substitutes), based upon the scalp defect type. Here we describe six cases of patients with total scalp avulsion, which required a combined reconstruction with a split-thickness skin graft (STSG) and Integra
Language	English
Publishing date	2023-03-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12062167
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Article ; Online: Olfactory recovery following omicron variant infection: a psychophysical prospective case-control study with six-month follow up.

Vaira, Luigi Angelo / Boscolo-Rizzo, Paolo / Lechien, Jerome R / Mayo-Yáñez, Miguel / Petrocelli, Marzia / Pistidda, Laura / Salzano, Giovanni / Maglitto, Fabio / Hopkins, Claire / De Riu, Giacomo

The Journal of laryngology and otology

2023 Volume 137, Issue 12, Page(s) 1395–1400

Abstract: Objective: This study aimed to evaluate the recovery of olfactory function at six months in individuals infected with the coronavirus disease 2019 omicron variant, using psychophysical tests.: Methods: A prospective case-control study that included ... ...

Abstract	Objective: This study aimed to evaluate the recovery of olfactory function at six months in individuals infected with the coronavirus disease 2019 omicron variant, using psychophysical tests. Methods: A prospective case-control study that included severe acute respiratory syndrome coronavirus-2 patients infected in February and March 2022 was conducted. Patients underwent the Sniffin' Sticks test within 10 days of infection and again after at least 6 months. The olfactory scores were compared with those of a control group. Results: In all, 102 patients and 120 controls were enrolled in the study. At baseline, 26 patients (25.5 per cent) self-reported smell loss. The median threshold, discrimination and identification score was 33.6 (interquartile range, 12.5) for the cases and 36.5 (interquartile range, 4.38) for the controls ( Conclusion: Six months after infection, the prevalence of olfactory dysfunction in patients did not differ significantly from the control population.
MeSH term(s)	Humans ; Olfaction Disorders/epidemiology ; Olfaction Disorders/etiology ; Case-Control Studies ; Follow-Up Studies ; Smell ; Anosmia/etiology
Language	English
Publishing date	2023-05-17
Publishing country	England
Document type	Journal Article
ZDB-ID	218299-3
ISSN	1748-5460 ; 0022-2151
ISSN (online)	1748-5460
ISSN	0022-2151
DOI	10.1017/S0022215123000877
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Article ; Online: Conservative treatment and implant rehabilitation of the mandible in a case of craniofacial fibrous dysplasia: a case report.

Petrocelli, Marzia / Kretschmer, Winfried

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

2014 Volume 72, Issue 5, Page(s) 902.e1–6

Abstract: We present a case of implant rehabilitation of the mandible in a young patient affected by craniofacial fibrous dysplasia. A computed tomography scan showed involvement of the left orbital contour and left maxilla, with total involvement of the mandible. ...

Abstract	We present a case of implant rehabilitation of the mandible in a young patient affected by craniofacial fibrous dysplasia. A computed tomography scan showed involvement of the left orbital contour and left maxilla, with total involvement of the mandible. We performed conservative surgical treatment from 2004 to 2011 to reconstruct and recontour the orbital and mandible region. Next, we performed implant rehabilitation of the mandible. This case emphasizes the importance of conservative and nondemolition treatment to obtain excellent functional and esthetic results.
MeSH term(s)	Bone Transplantation/methods ; Child ; Dental Implantation, Endosseous/methods ; Dental Implants ; Esthetics ; Facial Bones/surgery ; Female ; Fibrous Dysplasia, Polyostotic/surgery ; Follow-Up Studies ; Humans ; Mandible/surgery ; Mandibular Diseases/surgery ; Mandibular Reconstruction/methods ; Maxillary Diseases/surgery ; Orbital Diseases/surgery ; Osseointegration/physiology ; Reconstructive Surgical Procedures/methods ; Skull/surgery ; Tomography, X-Ray Computed/methods
Chemical Substances	Dental Implants
Language	English
Publishing date	2014-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	392404-x
ISSN	1531-5053 ; 0278-2391
ISSN (online)	1531-5053
ISSN	0278-2391
DOI	10.1016/j.joms.2014.01.020
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Article ; Online: Validation of a self-administered olfactory and gustatory test for the remotely evaluation of COVID-19 patients in home quarantine.

Vaira, Luigi Angelo / Salzano, Giovanni / Petrocelli, Marzia / Deiana, Giovanna / Salzano, Francesco Antonio / De Riu, Giacomo

Head & neck

2020 Volume 42, Issue 7, Page(s) 1570–1576

Abstract: Background: Chemosensitive disorders are very frequent in the early stages of COVID-19 and in paucisymptomatic cases. These patients are typically placed in home quarantine. This study has the aim of validating a new olfactory and gustatory objective ... ...

Abstract	Background: Chemosensitive disorders are very frequent in the early stages of COVID-19 and in paucisymptomatic cases. These patients are typically placed in home quarantine. This study has the aim of validating a new olfactory and gustatory objective evaluation test in these patients. Methods: Thirty-three home-quarantined COVID-19 patients have undergone a self-administered chemosensitive test the day before the control swab. On this occasion, the patients underwent operator-administered already validated tests. The results were finally compared. Results: The differences between the results of the two tests were not significant for both the olfaction (P =.201) and the taste (P =.180). Conclusion: The olfactory and gustatory evaluation by self-administered test can be considered a valid tool, fundamental for obtaining objective qualitative and quantitative data on the extent of chemosensitive disorders in home-quarantined COVID-19 patients.
MeSH term(s)	Adult ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Female ; Humans ; Italy ; Male ; Middle Aged ; Olfaction Disorders/diagnosis ; Olfaction Disorders/virology ; Pandemics ; Pneumonia, Viral/complications ; Quarantine ; SARS-CoV-2 ; Self Report ; Sensory Thresholds ; Severity of Illness Index ; Taste Disorders/diagnosis ; Taste Disorders/virology
Keywords	covid19
Language	English
Publishing date	2020-05-09
Publishing country	United States
Document type	Journal Article ; Validation Study
ZDB-ID	645165-2
ISSN	1097-0347 ; 0148-6403 ; 1043-3074
ISSN (online)	1097-0347
ISSN	0148-6403 ; 1043-3074
DOI	10.1002/hed.26228
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Article ; Online: Trans-Oral Robotic Surgery: 14 Cases of Pleomorphic Adenoma of the Parapharyngeal Space.

Salzano, Giovanni / Togo, Giulia / Maglitto, Fabio / Borriello, Gerardo / Perri, Francesco / Audino, Giovanni / Vaira, Luigi Angelo / Maglione, Maria Grazia / Petrocelli, Marzia / Califano, Luigi / Ionna, Franco

The Journal of craniofacial surgery

2022 Volume 33, Issue 5, Page(s) 1587–1590

Abstract: Purpose: The aim of this study has been to describe our experience with pleomorphic adenomas of the parapharyngeal space (PPS) treated with trans-oral robotic surgery (TORS). Tumors arising from the PPS comprise less than 0.5% of all head and neck ... ...

Abstract	Purpose: The aim of this study has been to describe our experience with pleomorphic adenomas of the parapharyngeal space (PPS) treated with trans-oral robotic surgery (TORS). Tumors arising from the PPS comprise less than 0.5% of all head and neck tumors. Salivary gland tumors account for 40% to 50% of PPS lesions with pleomorphic adenomas representing the most common salivary tumors (80%-90%). Parapharyngeal space tumors cause nonspecific symptoms and may be difficult to diagnose. Methods: In our study a preoperative diagnosis was conducted by fine needle aspiration biopsy and magnetic resonance imaging and the results were used to plan the correct surgical approach. Results: In all cases we were able to employ TORS, a minimally invasive procedure that allows us to operate in narrow and anatomically complex spaces that we can only reach thanks to the use of well-articulated hand pieces. Conclusions: This report indicates that TORS is a safe surgical procedure for the excision of benign tumors of the PPS in selected cases.
MeSH term(s)	Adenoma, Pleomorphic/diagnostic imaging ; Adenoma, Pleomorphic/surgery ; Head and Neck Neoplasms ; Humans ; Parapharyngeal Space/diagnostic imaging ; Parapharyngeal Space/surgery ; Pharyngeal Neoplasms/diagnostic imaging ; Pharyngeal Neoplasms/pathology ; Pharyngeal Neoplasms/surgery ; Retrospective Studies ; Robotic Surgical Procedures/methods ; Salivary Gland Neoplasms/diagnostic imaging ; Salivary Gland Neoplasms/pathology ; Salivary Gland Neoplasms/surgery
Language	English
Publishing date	2022-01-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000008477
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Zs.A 3761: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Bad splits in bilateral sagittal split osteotomy: A retrospective comparative analysis of the use of different tools.

Salzano, Giovanni / Audino, Giovanni / Friscia, Marco / Vaira, Luigi Angelo / Biglio, Andrea / Maglitto, Fabio / Committeri, Umberto / Piombino, Pasquale / Bonavolontà, Paola / Petrocelli, Marzia / Perrotta, Stefania / Califano, Luigi

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

2022 Volume 50, Issue 7, Page(s) 543–549

Abstract: This study aims to analyse the relationship between the incidence of bad splits and the surgical tools adopteded to perform bilateral sagittal split ramus osteotomy (BSSRO).BSSROs performed by the same experienced surgeon period were reviewed, ... ...

Abstract	This study aims to analyse the relationship between the incidence of bad splits and the surgical tools adopteded to perform bilateral sagittal split ramus osteotomy (BSSRO).BSSROs performed by the same experienced surgeon period were reviewed, retrospectively. The patients were divided into three groups according to the surgical instrument used to perform the osteotomy: a Lindemann burr, reciprocating saw or piezosurgery. Among the 1120 BSSROs performed, 5 bad fractures were detected during the observation period: 3 among patients operated with the Lindemann burr (0.8%) and 2 among those operated with a reciprocating saw (0.5%). There was no significant correlation between the bad split rate and age and gender of the patients, the type of malocclusion or the type of instrument used to perform the osteotomy. Within the limitations of the study it seems that the the choice of the osteotomy tool for BSSRO does not influence the rate of bad fractures and, therefore, the selection of the osteotmy tool should be left to the discretion of the surgeon.
MeSH term(s)	Humans ; Mandible/surgery ; Osteotomy, Sagittal Split Ramus ; Piezosurgery ; Retrospective Studies
Language	English
Publishing date	2022-07-02
Publishing country	Scotland
Document type	Comparative Study ; Journal Article
ZDB-ID	91267-0
ISSN	1878-4119 ; 1010-5182 ; 0301-0503
ISSN (online)	1878-4119
ISSN	1010-5182 ; 0301-0503
DOI	10.1016/j.jcms.2022.06.009
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Article: Validation of a self-administered olfactory and gustatory test for the remotely evaluation of COVID-19 patients in home quarantine

Vaira, Luigi Angelo / Salzano, Giovanni / Petrocelli, Marzia / Deiana, Giovanna / Salzano, Francesco Antonio / De Riu, Giacomo

Head Neck

Abstract: BACKGROUND: Chemosensitive disorders are very frequent in the early stages of COVID-19 and in paucisymptomatic cases. These patients are typically placed in home quarantine. This study has the aim of validating a new olfactory and gustatory objective ... ...

Abstract	BACKGROUND: Chemosensitive disorders are very frequent in the early stages of COVID-19 and in paucisymptomatic cases. These patients are typically placed in home quarantine. This study has the aim of validating a new olfactory and gustatory objective evaluation test in these patients. METHODS: Thirty-three home-quarantined COVID-19 patients have undergone a self-administered chemosensitive test the day before the control swab. On this occasion, the patients underwent operator-administered already validated tests. The results were finally compared. RESULTS: The differences between the results of the two tests were not significant for both the olfaction (P =.201) and the taste (P =.180). CONCLUSION: The olfactory and gustatory evaluation by self-administered test can be considered a valid tool, fundamental for obtaining objective qualitative and quantitative data on the extent of chemosensitive disorders in home-quarantined COVID-19 patients.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #155343
Database	COVID19

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Article ; Online: Validation of a self‐administered olfactory and gustatory test for the remotely evaluation of COVID ‐19 patients in home quarantine

Vaira, Luigi Angelo / Salzano, Giovanni / Petrocelli, Marzia / Deiana, Giovanna / Salzano, Francesco Antonio / De Riu, Giacomo

Head & Neck

2020 Volume 42, Issue 7, Page(s) 1570–1576

Keywords	Otorhinolaryngology ; covid19
Language	English
Publisher	Wiley
Publishing country	us
Document type	Article ; Online
ISSN	1043-3074
DOI	10.1002/hed.26228
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Short-Term Efficacy and Safety of Oral and Nasal Corticosteroids in COVID-19 Patients with Olfactory Dysfunction: A European Multicenter Study

Saussez, Sven / Vaira, Luigi Angelo / Chiesa-Estomba, Carlos M. / Bon, Serge-D. Le / Horoi, Mihaela / Deiana, Giovanna / Petrocelli, Marzia / Boelpaep, Philippe / Salzano, Giovanni / Khalife, Mohamad / Hans, Stephane / De Riu, Giacomo / Hopkins, Claire / Lechien, Jerome R.

Pathogens. 2021 June 04, v. 10, no. 6

2021

Abstract: Background: The objective of this study was to investigate the efficacy and safety of early administration of oral corticosteroids (OC) or nasal corticosteroids (NC) as an add-on to olfactory training (OT) versus OT alone in patients with olfactory ... ...

Abstract	Background: The objective of this study was to investigate the efficacy and safety of early administration of oral corticosteroids (OC) or nasal corticosteroids (NC) as an add-on to olfactory training (OT) versus OT alone in patients with olfactory dysfunction (OD) related to coronavirus disease 2019 (COVID-19). Methods: Patients with a positive diagnosis of COVID-19 and OD were prospectively recruited from March 22 to December 15, 2020 from 4 European hospitals. Patients had confirmed OD on psychophysical testing. All patients undertook OT, with add-on 10 days of OC (group 1: OC + OT), or 1 month of NC (group 2: NC + OT) or olfactory training alone (group 3: OT). Olfactory evaluations (Sniffin’Sticks tests) were carried out at the time of inclusion, 1 and 2 months after the start of the therapeutic course. Results: A total of 152 hyposmic or anosmic patients completed the study. Group 1, 2 and 3 included 59, 22 and 71 patients, respectively and all patient groups were comparable regarding baseline Sniffin’Sticks tests. The median Sniffin’Sticks test values significantly improved from pre- to post-intervention in all groups. The increase of Sniffin’Sticks test values was higher in group 1 (OC + OT) compared with groups 2 and 3 (p < 0.001) at one month after treatment but did not remain so at 2 months. Groups 1, 2 and 3, respectively, presented parosmia in 20/71 (28.2%), 9/22 (40.9%) and 42/71 (59.2%) patients. This difference was statistically significant between group 1 and 3 (p < 0.001). There were no patients with a worsening of the disease or an increase of the severity of the COVID-19 symptoms. Conclusions: The use of OCs in patients with OD related to mild COVID-19 is generally well-tolerated without any case of deterioration of symptoms. OC is associated with greater improvement in psychophysical olfactory evaluations at 1-month post-treatment but there was no difference at 2 months. Parosmia may be reduced following treatment with OC and NC. On the basis of these preliminary results, it is possible to state that considering the 2 months efficacy of OC and NC with respect to the OT alone and the risk-benefit ratio, the benefit to start a specific treatment of COVID-19 related OD cannot be demonstrated and there is a need for a randomised controlled trial to assess this further.
Keywords	COVID-19 infection ; adrenal cortex hormones ; nose ; olfactory disorders ; patients ; randomized clinical trials ; therapeutics
Language	English
Dates of publication	2021-0604
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens10060698
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Validation of the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool: a new tool to assess the quality of health information provided by AI platforms.

Vaira, Luigi Angelo / Lechien, Jerome R / Abbate, Vincenzo / Allevi, Fabiana / Audino, Giovanni / Beltramini, Giada Anna / Bergonzani, Michela / Boscolo-Rizzo, Paolo / Califano, Gianluigi / Cammaroto, Giovanni / Chiesa-Estomba, Carlos M / Committeri, Umberto / Crimi, Salvatore / Curran, Nicholas R / di Bello, Francesco / di Stadio, Arianna / Frosolini, Andrea / Gabriele, Guido / Gengler, Isabelle M /

Lonardi, Fabio / Maglitto, Fabio / Mayo-Yáñez, Miguel / Petrocelli, Marzia / Pucci, Resi / Saibene, Alberto Maria / Saponaro, Gianmarco / Tel, Alessandro / Trabalzini, Franco / Trecca, Eleonora M C / Vellone, Valentino / Salzano, Giovanni / De Riu, Giacomo

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

2024

Abstract: Background: The widespread diffusion of Artificial Intelligence (AI) platforms is revolutionizing how health-related information is disseminated, thereby highlighting the need for tools to evaluate the quality of such information. This study aimed to ... ...

Abstract	Background: The widespread diffusion of Artificial Intelligence (AI) platforms is revolutionizing how health-related information is disseminated, thereby highlighting the need for tools to evaluate the quality of such information. This study aimed to propose and validate the Quality Assessment of Medical Artificial Intelligence (QAMAI), a tool specifically designed to assess the quality of health information provided by AI platforms. Methods: The QAMAI tool has been developed by a panel of experts following guidelines for the development of new questionnaires. A total of 30 responses from ChatGPT4, addressing patient queries, theoretical questions, and clinical head and neck surgery scenarios were assessed by 27 reviewers from 25 academic centers worldwide. Construct validity, internal consistency, inter-rater and test-retest reliability were assessed to validate the tool. Results: The validation was conducted on the basis of 792 assessments for the 30 responses given by ChatGPT4. The results of the exploratory factor analysis revealed a unidimensional structure of the QAMAI with a single factor comprising all the items that explained 51.1% of the variance with factor loadings ranging from 0.449 to 0.856. Overall internal consistency was high (Cronbach's alpha = 0.837). The Interclass Correlation Coefficient was 0.983 (95% CI 0.973-0.991; F (29,542) = 68.3; p < 0.001), indicating excellent reliability. Test-retest reliability analysis revealed a moderate-to-strong correlation with a Pearson's coefficient of 0.876 (95% CI 0.859-0.891; p < 0.001). Conclusions: The QAMAI tool demonstrated significant reliability and validity in assessing the quality of health information provided by AI platforms. Such a tool might become particularly important/useful for physicians as patients increasingly seek medical information on AI platforms.
Language	English
Publishing date	2024-05-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1017359-6
ISSN	1434-4726 ; 0937-4477
ISSN (online)	1434-4726
ISSN	0937-4477
DOI	10.1007/s00405-024-08710-0
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