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  1. Book: Ecocardiografia '93

    Pezzano, Antonio

    Milano 27 -30 Aprile 1993 ; a joint meeting with the American Society of Echocardiography

    (Atti del ... congresso nazionale SIEC / Società Italiana di Ecocardiografia ; 6)

    1993  

    Institution Societa Italiana di Ecografia Cardiovascolare
    American Society of Echocardiography
    Series title Atti del ... congresso nazionale SIEC / Società Italiana di Ecocardiografia ; 6
    Atti del ... congresso nazionale SIEC
    Collection Atti del ... congresso nazionale SIEC
    Language Italian ; English
    Size 244 S. : Ill., graph. Darst.
    Publishing country Italy
    Document type Book
    HBZ-ID HT013352949
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Conference proceedings: Ecocardiografia '93

    Pezzano, Antonio

    communicazioni del VI congresso nazionale SIEC ; Milano 27 - 30 aprile 1993

    (Giornale italiano di ecografia cardiovascolare ; 3,1, Suppl.)

    1993  

    Institution Societa Italiana di Ecografia Cardiovascolare
    Author's details a cura di: A. Pezzano
    Series title Giornale italiano di ecografia cardiovascolare ; 3,1, Suppl.
    Collection
    Keywords Echocardiography / congresses
    Language Italian
    Size X, 66 S.
    Publisher Centro Scientifico Ed
    Publishing place Torino
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT007345296
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Can Seismocardiogram Fiducial Points Be Used for the Routine Estimation of Cardiac Time Intervals in Cardiac Patients?

    Işilay Zeybek, Zeynep Melike / Racca, Vittorio / Pezzano, Antonio / Tavanelli, Monica / Di Rienzo, Marco

    Frontiers in physiology

    2022  Volume 13, Page(s) 825918

    Abstract: The indexes of cardiac mechanics can be derived from the cardiac time intervals, CTIs, i.e., the timings among the opening and closure of the aortic and mitral valves and the Q wave in the ECG. Traditionally, CTIs are estimated by ultrasound (US) ... ...

    Abstract The indexes of cardiac mechanics can be derived from the cardiac time intervals, CTIs, i.e., the timings among the opening and closure of the aortic and mitral valves and the Q wave in the ECG. Traditionally, CTIs are estimated by ultrasound (US) techniques, but they may also be more easily assessed by the identification of specific fiducial points (FPs) inside the waveform of the seismocardiogram (SCG), i.e., the measure of the thorax micro-accelerations produced by the heart motion. While the correspondence of the FPs with the valve movements has been verified in healthy subjects, less information is available on whether this methodology may be routinely employed in the clinical practice for the monitoring of cardiac patients, in which an SCG waveform distortion is expected because of the heart dysfunction. In this study we checked the SCG shape in 90 patients with myocardial infarction (MI), heart failure (HF), or transplanted heart (TX), referred to our hospital for rehabilitation after an acute event or after surgery. The SCG shapes were classified as traditional (T) or non-traditional (NT) on whether the FPs were visible or not on the basis of nomenclature previously proposed in literature. The T shape was present in 62% of the patients, with a higher ∓ prevalence in MI (79%). No relationship was found between T prevalence and ejection fraction (EF). In 20 patients with T shape, we checked the FPs correspondence with the real valve movements by concomitant SCG and US measures. When compared with reference values in healthy subjects available in the literature, we observed that the Echo vs. FP differences are significantly more dispersed in the patients than in the healthy population with higher differences for the estimation of the mitral valve closure (-17 vs. 4 ms on average). Our results indicate that not every cardiac patient has an SCG waveform suitable for the CTI estimation, thus before starting an SCG-based CTI monitoring a preliminary check by a simultaneous SCG-US measure is advisable to verify the applicability of the methodology.
    Language English
    Publishing date 2022-03-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.825918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Short- and long-term effects of a cardiac rehabilitation program in patients implanted with a left ventricular assist device.

    Scaglione, Anna / Panzarino, Claudia / Modica, Maddalena / Tavanelli, Monica / Pezzano, Antonio / Grati, Paola / Racca, Vittorio / Toccafondi, Anastasia / Bordoni, Bruno / Verde, Alessandro / Cartella, Iside / Castiglioni, Paolo

    PloS one

    2021  Volume 16, Issue 12, Page(s) e0259927

    Abstract: The efficacy of cardiac rehabilitation in heart-failure patients who received a left-ventricular assist device (LVAD) instead of heart transplantation (HTx) is still unclear. This study aims to evaluate whether cardiac rehabilitation is beneficial in ... ...

    Abstract The efficacy of cardiac rehabilitation in heart-failure patients who received a left-ventricular assist device (LVAD) instead of heart transplantation (HTx) is still unclear. This study aims to evaluate whether cardiac rehabilitation is beneficial in LVAD as HTx patients in the short term and whether its effects in LVAD patients persist over time. Twenty-five LVAD patients were evaluated by functional and psychological tests at admission (T0) and discharge (T1) of a 4-week inpatient structured rehabilitation program, and follow-ups 3 (T2), 6 (T3), and 12 months (T4) after discharge. Twenty-five matched HTx patients were also studied from T0 to T1 to compare the improvements in the six-minute walk test (6MWT). The quality-of-life scores substantially improved in LVAD patients and the 6MWT showed the same functional recovery as in HTx patients from T0 to T1. After T1, numerous LVAD patients withdrew from the study. However, the 6MWT outcome increased further from T1 to T3, with a positive trend during the follow-ups. Hemoglobin and the ventilatory performance increased, and the psychological perception of heart-failure symptoms and pain further improved at T2. In conclusion, exercise-based rehabilitation programs provide similar beneficial effects in LVAD and HTx patients, without deterioration in LVAD patients up to 12 months after discharge.
    MeSH term(s) Aged ; Cardiac Surgical Procedures/adverse effects ; Cardiac Surgical Procedures/instrumentation ; Cardiac Surgical Procedures/methods ; Exercise Therapy/methods ; Female ; Heart Failure/rehabilitation ; Heart Failure/surgery ; Heart-Assist Devices ; Humans ; Male ; Middle Aged ; Postoperative Complications/rehabilitation ; Psychotherapy/methods
    Language English
    Publishing date 2021-12-01
    Publishing country United States
    Document type Journal Article ; Observational Study
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0259927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Carotid intima-media thickness.

    Pezzano, Antonio / La Carrubba, Salvatore / Gullace, Giuseppe

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2006  Volume 7, Issue 7, Page(s) 555–559

    Abstract: In advanced countries the incidence of cardiovascular diseases is constantly increasing. During the last century many resources were employed to investigate atherosclerosis in relation to the main risk factors and to modification of lifestyles. ... ...

    Abstract In advanced countries the incidence of cardiovascular diseases is constantly increasing. During the last century many resources were employed to investigate atherosclerosis in relation to the main risk factors and to modification of lifestyles. Technologies have been developed to identify atherosclerosis in the sub-clinical phase. Measurement of the carotid intima-media thickness (IMT) by B-mode ultrasound is a well-validated procedure to detect the early stages of atherosclerosis and to track progression of atherosclerosis whereas other techniques have limited utility because of their invasive nature or limited sensitivity and reproducibility. In comparison with angiography, B-mode ultrasound has greater sensitivity for detecting early atherosclerosis and plaques at risk of rupture. IMT is associated with the severity of atherosclerosis in different vascular districts and has been measured in several clinical studies in order to assess the influence of risk factors, therapies and diet. It is also validated for drug evaluation. In spite of this evidence IMT measurement is not routinely performed in patients with high and middle levels of risk for cardiovascular diseases. Scientific societies and specifically those involved in ultrasonography should promote wider recognition of the diagnostic power of ultrasonic IMT by emphasizing the low costs and low risk of use of the instruments and its major contribution to knowledge, evaluation and monitoring of the progression of atherosclerosis.
    MeSH term(s) Atherosclerosis/diagnostic imaging ; Carotid Arteries/diagnostic imaging ; Carotid Arteries/pathology ; Carotid Artery Diseases/diagnostic imaging ; Carotid Artery Diseases/pathology ; Humans ; Risk Factors ; Tunica Intima/diagnostic imaging ; Tunica Intima/pathology ; Ultrasonography
    Language English
    Publishing date 2006-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/01.JCM.0000234774.81077.a6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Asymptomatic Left Ventricular Dysfunction and Metabolic Syndrome: Results from an Italian Multicenter Study.

    La Carrubba, Salvatore / Todaro, Maria Chiara / Zito, Concetta / Antonini-Canterin, Francesco / Monte, Ines Paola / Caso, Pio / Colonna, Paolo / de Gregorio, Cesare / Pezzano, Antonio / Benedetto, Frank / Salvo, Giovanni Di / Carerj, Scipione / Bello, Vitantonio Di

    Journal of cardiovascular echography

    2017  Volume 23, Issue 4, Page(s) 96–101

    Abstract: Context: Metabolic syndrome (MS) is a cluster of interrelated common clinical disorders, including obesity, insulin resistance, glucose intolerance, hypertension and dyslipidemia, associated with a greater risk of atherosclerotic cardiovascular disease ... ...

    Abstract Context: Metabolic syndrome (MS) is a cluster of interrelated common clinical disorders, including obesity, insulin resistance, glucose intolerance, hypertension and dyslipidemia, associated with a greater risk of atherosclerotic cardiovascular disease than any of its individual components. Although MS is associated with increased cardiovascular risk (CVR), its relationship with heart failure (HF) and left ventricular (LV) dysfunction is not fully understood.
    Aims: We sought to determine whether MS is associated to LV systolic and diastolic dysfunction in a sample of patients with MS and no symptoms for HF.
    Subjects and methods: We enrolled 6422 consecutive asymptomatic patients admitted to echo-lab for a routine echocardiogram. We calculated LV systolic and diastolic function, by Simpson biplane method and validated Doppler parameters, respectively. MS was diagnosed if three or more CVR factors were found.
    Results: LV systolic function was evaluated in 6175 patients (96.2%). In the group of patients without MS (
    Conclusions: Our data show that asymptomatic LV systolic and diastolic dysfunction, is correlated with MS and demonstrate that echocardiography is a useful tool to detect patients at high risk for HF. Echocardiography in asymptomatic patients with MS may lead to a therapy initiation at early stages to prevent future cardiovascular events and HF.
    Language English
    Publishing date 2017-04-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2734045-4
    ISSN 2347-193X ; 2211-4122
    ISSN (online) 2347-193X
    ISSN 2211-4122
    DOI 10.4103/2211-4122.127410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The DAVES (Disfunzione Asintomatica VEntricolare Sinistra) study by the Italian Society of Cardiovascular Echography: rationale and design.

    Carerj, Scipione / Penco, Maria / La Carrubba, Salvatore / Salustri, Alessandro / Erlicher, Andrea / Pezzano, Antonio

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2006  Volume 7, Issue 7, Page(s) 457–463

    Abstract: Background: Diagnosis of heart failure (HF) is based on clinical signs, instrumental findings and response to treatment. The recent classification of the European Society of Cardiology identifies early stages of ventricular dysfunction not associated ... ...

    Abstract Background: Diagnosis of heart failure (HF) is based on clinical signs, instrumental findings and response to treatment. The recent classification of the European Society of Cardiology identifies early stages of ventricular dysfunction not associated with symptoms of HF (Stage A-B). However, only few data are available on the prevalence and prognostic value of asymptomatic left ventricular dysfunction.
    Methods: The SIEC (Società Italiana di Ecografia Cardiovascolare - Italian Society of Cardiovascular Echography) has planned a national multicenter observational study aimed to assess: (1) the prevalence of left ventricular (LV) systolic and diastolic dysfunction in asymptomatic subjects without a history of HF (transversal phase); (2) the relationship between cardiovascular risk factors and LV asymptomatic dysfunction; (3) the relationship between comorbidities and LV asymptomatic dysfunction; and (4) the incidence of cardiac events at follow-up (longitudinal phase). Data from 75 echocardiographic laboratories were recorded, merged, and analyzed using a dedicated software.
    Current status: Recruitment started in June 2003 and closed in February 2004. Overall, 16 099 patients (men, 8496; women, 7603; male: female ratio, 1.11) have been screened and 6679 (men, 3504; women, 3175; male: female ratio, 1.10) were enrolled. The follow-up is currently ongoing.
    MeSH term(s) Cardiac Output, Low/diagnosis ; Cardiac Output, Low/epidemiology ; Cardiovascular Diseases/epidemiology ; Comorbidity ; Epidemiologic Research Design ; Female ; Humans ; Italy ; Longitudinal Studies ; Male ; Prevalence ; Prognosis ; Prospective Studies ; Risk Factors ; Ultrasonography ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/epidemiology
    Language English
    Publishing date 2006-07
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/01.JCM.0000234762.68509.7b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Valvulopathies in sub-Saharan African children: patterns, humanitarian interventions and cardiac surgical problems.

    Ferratini, Maurizio / Marianeschi, Stefano / Santoro, Francesco / Vitali, Ettore / Ripamonti, Vittorino / De Maria, Renata / Torri, Anna / Pezzano, Antonio / Moraschi, Andrea / Tavano, Davide / Pesaresi, Marilena / Martinelli, Luigi

    International journal of cardiology

    2013  Volume 165, Issue 2, Page(s) 237–241

    Abstract: Despite the high burden of rheumatic fever in sub-Saharan African, there is currently no sustained and comprehensive strategy to control the disease. Consequently in this area the number of patients affected by rheumatic valve disease (RVD), most with a ... ...

    Abstract Despite the high burden of rheumatic fever in sub-Saharan African, there is currently no sustained and comprehensive strategy to control the disease. Consequently in this area the number of patients affected by rheumatic valve disease (RVD), most with a surgical indication, is 10-20 fold higher than in industrialised countries and estimates indicate that more than 50% of African RVD patients will die before age 25. In this paper, we review clinical and management issues of RVD in children in sub-Saharan Africa. Severe heart failure and undergrowth are the prevalent presentation of the illness. Severe mitral regurgitation is the commonest rheumatic valvulopathy observed in the first and second decades. Valve repair, the approach of choice, may be associated with unfavourable outcomes in patients with extreme cardiomegaly. In young people, whenever correct anticoagulation may reasonably be achieved, mechanical mitral prostheses should be preferred, even in females. The early deterioration of biologic mitral prostheses strongly suggests limiting their use to those cases in which correct anticoagulation is not feasible. In most sub-Saharan countries, socioeconomic factors strongly limit access to health services and to cardiac surgery in particular. Efforts to overcome these barriers have resulted in humanitarian projects along two patterns: creation of high tech on site health care structures or transfer of children with complex diseases to receive highly specialised cardiac surgical care abroad. We summarise the experience of our programme that followed the latter approach.
    MeSH term(s) Africa South of the Sahara/ethnology ; Altruism ; Cardiac Surgical Procedures/economics ; Heart Valve Diseases/economics ; Heart Valve Diseases/ethnology ; Heart Valve Diseases/surgery ; Humans ; Rheumatic Heart Disease/diagnosis ; Rheumatic Heart Disease/economics ; Rheumatic Heart Disease/ethnology ; Rheumatic Heart Disease/surgery
    Language English
    Publishing date 2013-05-10
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2012.03.069
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  9. Article: Valutazione della riserva di flusso coronarico mediante ecocardiografia color Doppler transtoracica in pazienti sottoposti ad angioplastica primaria: relazioni con il recupero della funzione ventricolare sinistra.

    Pezzano, Antonio / Valentini, Mariaconsuelo / Comerio, Gabriella / Tavanelli, Monica / Racca, Vittorio / Brambilla, Gabriella / Ferratini, Maurizio

    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology

    2005  Volume 6, Issue 10, Page(s) 660–666

    Abstract: Background: The aim of this study was to determine the relationship between coronary flow reserve measurement by transthoracic Doppler echocardiography in recent acute myocardial infarction treated with primary coronary angioplasty (PTCA) and recovery ... ...

    Title translation Coronary flow reserve assessment by transthoracic color Doppler echocardiography after primary angioplasty: relationship with recovery of left ventricular function.
    Abstract Background: The aim of this study was to determine the relationship between coronary flow reserve measurement by transthoracic Doppler echocardiography in recent acute myocardial infarction treated with primary coronary angioplasty (PTCA) and recovery of left ventricular function.
    Methods: Forty-one consecutive patients (3 patients excluded for not good quality of the Doppler signal) have been studied with: (1) recent first acute myocardial infarction treated with primary PTCA within 6 hours of pain onset; (2) optimal angioplasty result with stent deployment, anti-IIb/IIIa infusion and TIMI 3 flow; (3) lack of type 1 diabetes and/or hypertension; (4) good tolerance to adenosine. Transthoracic Doppler echocardiography was used to record coronary flow velocities in the distal left anterior descending and posterior descending coronary arteries at rest and after infusion of adenosine. Coronary flow reserve was measured after 11 +/- 1 days from the acute event. The wall motion score index (WMSI) was calculated at baseline, 1 month and 3 months from myocardial infarction.
    Results: Patients of group A (n = 29 with coronary flow reserve > or = 1.6) showed a progressive and significant recovery of left ventricular function at follow-up. Patients of group B (n = 9 with coronary flow reserve < 1.6) had persistent left ventricular dysfunction at 3 months (ANOVA, p < 0.0001). WMSI was 1.64 +/- 0.26 in group A and 1.81 +/- 0.16 in group B (p = 0.09) at baseline; 1.30 +/- 0.26 in group A and 1.75 +/- 0.16 in group B (p < 0.0001) at 1 month; and 1.20 +/- 0.25 in group A and 1.73 +/- 0.17 in group B at 3 months. There was an inverse correlation between coronary flow reserve and WMSI at 1 month (r = -0.564, p < 0.0001), and at 3 months (r = -0.583, p < 0.0001). On multivariate analysis baseline WMSI and coronary flow reserve were the only predictors of 1-month WMSI recovery and of WMSI recovery at 3 months.
    Conclusions: Coronary flow reserve by transthoracic color Doppler echocardiography is a useful method for predicting left ventricular function recovery in patients after primary PTCA.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Angioplasty, Balloon, Coronary ; Coronary Circulation ; Data Interpretation, Statistical ; Echocardiography, Doppler, Color ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Stents ; Time Factors ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Function, Left
    Language Italian
    Publishing date 2005-10
    Publishing country Italy
    Document type Comparative Study ; English Abstract ; Evaluation Studies ; Journal Article
    ZDB-ID 2012387-5
    ISSN 1972-6465 ; 1129-4728 ; 1129-471X
    ISSN (online) 1972-6465
    ISSN 1129-4728 ; 1129-471X
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  10. Article: Transmitral pulsed-Doppler echocardiography is a more accurate technique compared with two-dimensional echocardiography using dobutamine, in patients with one vessel coronary artery disease.

    Bajraktari, Gani / Qirko, Spiro / Fusco, Rossana / Milazzo, Angela / Xhaxho, Brunilda / Pezzano, Antonio

    European journal of heart failure

    2003  Volume 5, Issue 1, Page(s) 63–72

    Abstract: Unlabelled: To examine the effects of dobutamine on pulsed-Doppler left ventricular filling indices and its utility for evaluation of CAD we studied 14 patients with normal coronary arteries (Group 1) and 39 patients with significant CAD (>70% diameter ... ...

    Abstract Unlabelled: To examine the effects of dobutamine on pulsed-Doppler left ventricular filling indices and its utility for evaluation of CAD we studied 14 patients with normal coronary arteries (Group 1) and 39 patients with significant CAD (>70% diameter stenosis). Patients with coronary artery disease (CAD) were divided into two groups: patients with one-vessel coronary disease (Group 2); and those with multivessel CAD (Group 3). After stopping cardioactive treatment, patients underwent incremental dobutamine stress (5, 10, 20, 30 and 40 microg/kg/min) during pulsed-Doppler interrogation of diastolic filling with simultaneous heart rate and blood pressure measurements. The following transmitral Doppler variables were measured at baseline and at peak-dose of dobutamine: peak early (E) and peak atrial (A) velocity; E/A ratio; acceleration time (AT) and deceleration time (DT) of E wave; isovolumic relaxation time (IVRT); and time-velocity integral (TVI). Two-dimensional echocardiography was performed to detect regional asinergy and analyzed using a 16 segment model.
    Results: Normals and CAD patients showed comparable changes in heart rate and blood pressure (P=NS between groups). Intergroup analysis of the changes of transmitral flow showed the significant changes for these indices (P<0.001): E velocity (-2.78+/-10.04, 12.4+/-9.4 and 16.47+/-10.65 cm/s); AT of E wave (1.66+/-2.47, -5.2+/-1.38 and -4.66+/-2.39 m/s(2)); DT of E wave (-0.23+/-0.18, 0.2+/-0.2 and 0.2+/-0.28 m/s(2)); and TVI of transmitral flow (-1.26+/-0.7, 3.5+/-1.75 and 4.1+/-1.66 cm), respectively for Groups 1, 2 and 3. All other transmitral Doppler variables showed insignificant changes (P=NS) to dobutamine between groups. It is important that the significance of these changes were the same for patients with one-vessel and those with multivessel coronary disease. In conclusion, during dobutamine stress testing, patients with CAD, had an abnormal response of these transmitral Doppler indices: E wave; AT of E wave; DT of E wave; and the TVI of transmitral flow. The abnormal responses of these Doppler indices of left ventricular filling are more accurate markers of significant single vessel CAD than new wall motion abnormalities during conventional DSE.
    MeSH term(s) Adrenergic beta-Agonists/administration & dosage ; Aged ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/physiopathology ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/physiopathology ; Dobutamine/administration & dosage ; Dose-Response Relationship, Drug ; Echocardiography/methods ; Echocardiography, Doppler, Pulsed/methods ; Echocardiography, Stress ; Female ; Hemodynamics/drug effects ; Humans ; Male ; Middle Aged ; Mitral Valve/diagnostic imaging ; Observer Variation ; Prospective Studies ; Sensitivity and Specificity
    Chemical Substances Adrenergic beta-Agonists ; Dobutamine (3S12J47372)
    Language English
    Publishing date 2003-01
    Publishing country England
    Document type Comparative Study ; Evaluation Studies ; Journal Article
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1016/s1388-9842(02)00030-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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