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  1. Article ; Online: Positive impact of lockdown on COVID-19 outbreak in Thailand.

    Dechsupa, Sinsuda / Assawakosri, Suvichada / Phakham, Suphattra / Honsawek, Sittisak

    Travel medicine and infectious disease

    2020  Volume 36, Page(s) 101802

    MeSH term(s) Betacoronavirus ; COVID-19 ; Centers for Disease Control and Prevention, U.S. ; China ; Coronavirus ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Thailand ; United States
    Keywords covid19
    Language English
    Publishing date 2020-06-20
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6236: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Positive impact of lockdown on COVID-19 outbreak in Thailand

    Dechsupa, Sinsuda / Assawakosri, Suvichada / Phakham, Suphattra / Honsawek, Sittisak

    Travel Medicine and Infectious Disease

    2020  Volume 36, Page(s) 101802

    Keywords Public Health, Environmental and Occupational Health ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101802
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6236: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Cytokine Profiling and Intra-Articular Injection of Autologous Platelet-Rich Plasma in Knee Osteoarthritis.

    Riewruja, Kanyakorn / Phakham, Suphattra / Sompolpong, Patlapa / Reantragoon, Rangsima / Tanavalee, Aree / Ngarmukos, Srihatach / Udomsinprasert, Wanvisa / Suantawee, Tanyawan / Dechsupa, Sinsuda / Honsawek, Sittisak

    International journal of molecular sciences

    2022  Volume 23, Issue 2

    Abstract: Osteoarthritis (OA) is a degenerative joint disease leading to joint pain and stiffness. Due to lack of effective treatments, physical and psychological disabilities caused by OA have a detrimental impact on the patient's quality of life. Emerging ... ...

    Abstract Osteoarthritis (OA) is a degenerative joint disease leading to joint pain and stiffness. Due to lack of effective treatments, physical and psychological disabilities caused by OA have a detrimental impact on the patient's quality of life. Emerging evidence suggests that intra-articular injection of platelet-rich plasma (PRP) may provide favorable results since PRP comprises not only a high level of platelets but also a huge amount of cytokines, chemokines, and growth factors. However, the precise mechanism and standardization method remain uncertain. This study aimed to examine cytokine profiling in both PRP and platelet-poor plasma (PPP) of knee OA patients and to determine the effects of PRP on OA chondrocytes and knee OA patients. PRP contained a wide variety of cytokines, chemokines, growth factors, and autologous intra-articular PRP injection resulted in favorable outcomes in knee OA patients. Significant increases in levels of IL-1, IL-2, IL-7, IL-8, IL-9, IL-12, TNF-α, IL-17, PDGF-BB, bFGF, and MIP-1β were detected in PRP compared to PPP (
    MeSH term(s) Aged ; Biomarkers ; Cell Movement ; Cell Proliferation ; Chondrocytes/metabolism ; Cytokines/metabolism ; Disease Management ; Disease Susceptibility ; Female ; Humans ; Inflammation Mediators ; Male ; Middle Aged ; Osteoarthritis, Knee/diagnosis ; Osteoarthritis, Knee/etiology ; Osteoarthritis, Knee/metabolism ; Osteoarthritis, Knee/therapy ; Platelet-Rich Plasma ; Treatment Outcome
    Chemical Substances Biomarkers ; Cytokines ; Inflammation Mediators
    Language English
    Publishing date 2022-01-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23020890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Two or four injections of platelet-rich plasma for osteoarthritic knee did not change synovial biomarkers but similarly improved clinical outcomes.

    Ngarmukos, Srihatach / Tanavalee, Chotetawan / Amarase, Chavarin / Phakham, Suphattra / Mingsiritham, Warayapa / Reantragoon, Rangsima / Leearamwat, Nitigorn / Kongkaew, Thidarat / Tharakhet, Kittipan / Honsawek, Sittisak / Dechsupa, Sinsuda / Tanavalee, Aree

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 23603

    Abstract: We compared two and four intra-articular injections of platelet-rich plasma (PRP) in terms of changes of synovial cytokines and clinical outcomes. One hundred twenty-five patients having knee osteoarthritis (OA) underwent PRP injections at a 6-week ... ...

    Abstract We compared two and four intra-articular injections of platelet-rich plasma (PRP) in terms of changes of synovial cytokines and clinical outcomes. One hundred twenty-five patients having knee osteoarthritis (OA) underwent PRP injections at a 6-week interval. Before each PRP injection, synovial fluid aspiration was collected for investigation. Patients were divided into two or four intra-articular PRP injections (group A and B, respectively). Changes in synovial biomarkers were compared with the baseline levels of both groups, and clinical outcomes were evaluated until one year. Ninety-four patients who had completed synovial fluid collection were included for final evaluation, 51 in group A and 43 in group B. There were no differences in mean age, gender, body mass index (BMI), and radiographic OA grading. The average platelet count and white blood cell count in PRP were 430,000/µL and 200/ µL, respectively. There were no changes of synovial inflammatory cytokines (IL-1β, IL-6, IA-17A, and TNF-alpha), anti-inflammatory cytokines (IL-4, IL-10, IL-13, and IL-1RA), and growth factors (TGF-B1, VEGF, PDGF-AA, and PDGF-BB) between baseline levels and six weeks in group A, and 18 weeks in group B. Both groups had significantly improved clinical outcomes from six weeks including visual analog scale (VAS), patient-reported outcome measures [PROMs; Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index and Short Form-12 (SF-12)], with a significant delayed improvement of performance-based measures [PBMs; time up and go (TUG), 5-time sit to stand test (5 × SST), and 3-min walk test (3-min WT)]. In conclusion, two- or four-PRP intra-articular injection at a 6-week interval for knee OA demonstrated no changes of synovial cytokines and growth factors but similarly improved clinical outcomes from 6 weeks until 1 year.
    MeSH term(s) Aged ; Biomarkers/metabolism ; Female ; Humans ; Injections, Intra-Articular ; Male ; Middle Aged ; Osteoarthritis, Knee/therapy ; Platelet-Rich Plasma ; Synovial Membrane/metabolism ; Treatment Outcome
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-12-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-03081-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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