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  1. Article: Loin pain haematuria syndrome 1967-2020: a review.

    Annear, Nicholas M P / Vanmassenhove, Jill / Lameire, Norbert / Phillips, Malcolm E / Eastwood, John B

    Clinical kidney journal

    2024  Volume 17, Issue 3, Page(s) sfae034

    Abstract: The purpose of this retrospective review is to question the validity of the condition 'loin pain haematuria syndrome' (LPHS). We highlight the possibility that most patients regarded as having LPHS have a psychiatric/psychological basis for their ... ...

    Abstract The purpose of this retrospective review is to question the validity of the condition 'loin pain haematuria syndrome' (LPHS). We highlight the possibility that most patients regarded as having LPHS have a psychiatric/psychological basis for their symptoms, particularly loin pain. Because of this, and because it recurs despite treatment, the review also questions the use of treatments that are invasive, expensive, and carry considerable morbidity.
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfae034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Refeeding syndrome as described in 1507 by Antonio Benivieni in Florence.

    De Santo, Natale G / Bisaccia, Carmela / Phillips, Malcolm E / De Santo, Luca S

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2020  Volume 37, Issue 8, Page(s) 1411–1416

    Abstract: In 1981, Weinsier and Krumdieck described death resulting from overzealous total parenteral nutrition in two chronically malnourished, but stable, patients given aggressive total parenteral nutrition. This was the birth of what is now called the ... ...

    Abstract In 1981, Weinsier and Krumdieck described death resulting from overzealous total parenteral nutrition in two chronically malnourished, but stable, patients given aggressive total parenteral nutrition. This was the birth of what is now called the refeeding syndrome, a nutrition-related disorder associated with severe electrolyte disturbances. The purpose of this work is to demonstrate that refeeding syndrome was first described medically in Florence by Antonio Benivieni in 1507 in his book On Some Hidden and Remarkable Causes of Diseases and Cures. What we now know as refeeding syndrome was described in Report No. LVII of that book. The condition occurred as a result of the famine that affected Florence in 1496. The report documents (i) death due to starvation, (ii) death due to ingestion of deteriorated/toxic foods (inevitable in times of famine when healthy food is scarce), (iii) death caused by excessive food ingestion after forced, prolonged abstinence from food in adults, (iv) the death of breast-fed children and of their starved mothers eating to satiety and (v) the more favourable clinical outcome of those admitted to hospitals. It is possible that Benivieni was inspired by the description of the deaths of starved deserters in the book The Jewish War (70 AD) by the Romano-Jewish historian Flavius Josephus. Nevertheless, Benivieni wrote the first medical account of the central clinical features of refeeding syndrome. The main, broad clinical aspects of refeeding syndrome, described by Weinsier and Krumdieck in 1981, had been documented in medical literature four centuries earlier by Benivieni.
    MeSH term(s) Adult ; Child ; Humans ; Malnutrition ; Refeeding Syndrome/complications ; Water-Electrolyte Imbalance/complications
    Language English
    Publishing date 2020-12-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfaa295
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Carmelo Giordano (1930-2016): a giant in Nephrology.

    De Santo, Natale / De Pascale, Carlo / Quarto, Ernesto / Phillips, Malcolm E / Di Iorio, Biagio

    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia

    2017  Volume 34, Issue 2, Page(s) 165–187

    Abstract: Carmelo Giordano (Carmine, Louis, Joseph Giordano) was born in Naples on August 23, 1930 in the house of Rafael and Anna Tirone He received the MD cum laude in 1954. He was Fellow and assistant to Professor Flaviano Magrassi and studied nephrology at the ...

    Abstract Carmelo Giordano (Carmine, Louis, Joseph Giordano) was born in Naples on August 23, 1930 in the house of Rafael and Anna Tirone He received the MD cum laude in 1954. He was Fellow and assistant to Professor Flaviano Magrassi and studied nephrology at the Peter Bent Brigham Hospital, University of Harvard in Boston, under the guidance of John P. Merrill (1958-1960). He was nominated Professor of Nephrology at the University Federico II, Naples in 1975 and Professor of Medicine at the Second University of Naples (1986-2002). The National Institutes of Health of the United States in Bethesda financed his research for more than 20 years. He started low protein alimentation (Giordano-Giovannetti diet according to Geoffrey M. Berlyne) with or without addition of amino acids and ketoacids and devised formula diets for CKD infants and children. He demonstrated that 85% of CKD patients receiving a 25 g protein diet were in positive nitrogen balance. Later he introduced the concept of energy load from dialysate in CAPD and the assessment of amino acid losses during hemodialysis and peritoneal dialysis. He also researched the minimum protein requirement under CAPD regimens. He synthesized, with Professor Renato Esposito, oxystarch and oycellulose and introduced the use of carbon at low temperature and its regeneration at 90°C. He introduced wearable and portable artificial kidneys. He died in Naples on May 12, 2016.
    MeSH term(s) History, 20th Century ; History, 21st Century ; Italy ; Nephrology/history
    Language Italian
    Publishing date 2017-04
    Publishing country Italy
    Document type Biography ; Historical Article ; Journal Article ; Portraits
    ZDB-ID 1237110-5
    ISSN 1724-5990 ; 0393-5590
    ISSN (online) 1724-5990
    ISSN 0393-5590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Carmelo Giordano (1930-2016): uremia therapy by low protein alimentation and sorbents.

    De Santo, Natale G / Quarto, Ernesto / Phillips, Malcolm E / de Pascale, Carlo / Di Iorio, Biagio R

    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia

    2018  Volume 35, Issue Suppl 70, Page(s) 29–37

    MeSH term(s) Cellulose, Oxidized/history ; Cellulose, Oxidized/therapeutic use ; Diet, Protein-Restricted/history ; History, 20th Century ; History, 21st Century ; Italy ; Starch/analogs & derivatives ; Starch/history ; Starch/therapeutic use ; Uremia/history ; Uremia/therapy
    Chemical Substances Cellulose, Oxidized ; Starch (9005-25-8) ; dialdehyde starch (9047-50-1)
    Language English
    Publishing date 2018-02-23
    Publishing country Italy
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 1237110-5
    ISSN 1724-5990 ; 0393-5590
    ISSN (online) 1724-5990
    ISSN 0393-5590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Conference proceedings: Aminoaciduria in chronic renal failure--its relationship to vitamin D and parathyroid status

    Phillips, Malcolm E / Havard, Jayne / Otterud, Brith

    American journal of clinical nutrition July 1980. v. 33 (7)

    1980  

    Abstract: Abstract: Aminoaciduria is common and often severe in chronic renal failure patients, based on measurements of fractional clearances of amino acids. Additional measurements of vitamin D metabolites and serum parathyroid hormone (PTH) were made in ... ...

    Event/congress Symposium on Nutrition in Renal Disease (1979, Bologna)
    Abstract Abstract: Aminoaciduria is common and often severe in chronic renal failure patients, based on measurements of fractional clearances of amino acids. Additional measurements of vitamin D metabolites and serum parathyroid hormone (PTH) were made in patients with this condition, plus secondary hyperparathyroidism and osteomalacia. Treatment with vitamin D metabolites, particularly 1,25(OH)2D3, improved amino acid transport and amino acid reabsorption. The effect on transport was independent of PTH serum levels. Deficiency of 1,25(OH)2D3 may be a key factor in defective amino acid reabsorption in chronic renal failure patients, and in the tubular dysfunction found in such conditions as the Fanconi syndrome, rickets, and osteomalacia. The findings lend little support to the view that excess PTH causes aminoaciduria.
    Keywords amino acids ; renal failure ; vitamin D ; vitamin metabolism ; parathyroid hormone ; osteomalacia ; rickets ; absorption ; physiological transport
    Language English
    Dates of publication 1980-07
    Size p. 1541-1545., charts.
    Document type Article ; Conference proceedings
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: The Role of Parathyroidectomy in the Management of Hyperparathyroidism in Patients on Maintenance Haemodialysis and After Renal Transplantation

    Memmos, Dimitrios E. / Williams, Grant B. / Eastwood, John B. / Gordon, Elizabeth M. / Cochrane, Charles L. / Gower, Peter E. / Curtis, John R. / Phillips, Malcolm E. / Rainford, David J. / de.Wardener, Hugh E.

    Nephron

    1982  Volume 30, Issue 2, Page(s) 143–148

    Abstract: Between March 1964 and March 1980, 36 (34 dialysis, 2 transplant) of 327 patients accepted for the maintenance dialysis/transplantation programme at Charing Cross Hospital were submitted to parathyroidectomy. There were four main indications: persistent ... ...

    Abstract Between March 1964 and March 1980, 36 (34 dialysis, 2 transplant) of 327 patients accepted for the maintenance dialysis/transplantation programme at Charing Cross Hospital were submitted to parathyroidectomy. There were four main indications: persistent hypercalcaemia, progressive phalangeal erosions, aseptic necrosis of the femoral head and height loss with abnormal bone biopsy despite normal hand radiographs. At parathyroidectomy, 4 glands were removed in 1 patient, 3 ½ glands in 24, 3 glands in 7, 2 glands in 3 and a single large gland in 1 patient. The operation was followed by improvement in 28 patients, no change in 5, and progression of hyperparathyroidism in 3. 2 of the 28 patients who improved later relapsed and were treated with 1,25-(OH)2 vitamin D3. 4 patients were submitted to a further parathyroidectomy and improved considerably. We would conclude that, although parathyroidectomy is an effective and safe procedure, it is to be hoped that careful monitoring of bone state and early administration of 1,25-(OH)2 vitamin D3 may reduce the need for parathyroidectomy.
    Keywords Hyperparathyroidism ; Parathyroidectomy ; Maintenance haemodialysis
    Language English
    Publisher S. Karger AG
    Publishing place Basel
    Publishing country Switzerland
    Document type Article ; Online
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 0028-2766 ; 1660-8151 ; 0028-2766 ; 1660-8151
    ISSN (online) 1423-0186
    ISSN 0028-2766 ; 1660-8151
    DOI 10.1159/000182451
    Database Karger publisher's database

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