LIVIVO - Suchergebnisse -

Suchergebnis

Treffer 1 - 10 von insgesamt 34

Suchoptionen

Artikel ; Online: Depression, anxiety, and stress among frontline health workers during the second wave of COVID-19 in southern Vietnam

Anh Le Thi Ngoc / Chinh Dang Van / Phong Nguyen Thanh / Sonia Lewycka / Jennifer Ilo Van Nuil

PLOS Global Public Health, Vol 2, Iss 9, p e

A cross-sectional survey.

2022 Band 0000823

Abstract: Health workers around the world have taken on massive frontline roles in the fight against COVID-19, often under intense pressure and in the face of uncertainty. In this study, we determined the rates of depression, anxiety, stress and related factors ... ...

Abstract	Health workers around the world have taken on massive frontline roles in the fight against COVID-19, often under intense pressure and in the face of uncertainty. In this study, we determined the rates of depression, anxiety, stress and related factors among health workers in COVID-19 designated hospitals in southern Vietnam during the second wave of COVID-19. From July-September 2020, we collected self-administered surveys from 499 health workers in 14 hospitals that were designated for the care and treatment of patients with COVID-19. The survey included sections on demographics, co-morbid health conditions, symptoms experienced during patient care, a depression, anxiety and stress assessment (DASS-21), and other related factors. We used logistic regression models to identify factors associated with depression, anxiety and stress, and adjusted for confounding factors. 18%, 11.5%, 7.7% of participants had symptoms of depression, anxiety, and stress, respectively with the majority at mild and moderate levels. The risk factors for increased mental health impact included long working hours, experiencing physical symptoms, fear of transmission to family, COVID-19 related stigma, and worry when watching media about COVID-19. Psychological counseling and training in infection prevention were protective factors that reduced the risk of mental health problems. Further exploration of the association between physical symptoms experienced by health workers and mental health may guide interventions to improve health outcomes. More routine COVID-19 testing among health workers could reduce anxieties about physical symptoms and alleviate the fear of transmitting COVID-19 to family and friends. Medical institutions need to ensure that health workers have access to basic trainings prior to initiation of work, and mental health support during the pandemic and into the future.
Schlagwörter	Public aspects of medicine ; RA1-1270
Thema/Rubrik (Code)	300
Sprache	Englisch
Erscheinungsdatum	2022-01-01T00:00:00Z
Verlag	Public Library of Science (PLoS)
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

Volltext online

Volltext online

Zusatzmaterialien

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Artikel ; Online: Adapting to Climate-Change-Induced Drought Stress to Improve Water Management in Southeast Vietnam

Phong Nguyen Thanh / Thinh Le Van / Tuan Tran Minh / Tuyen Huynh Ngoc / Worapong Lohpaisankrit / Quoc Bao Pham / Alexandre S. Gagnon / Proloy Deb / Nhat Truong Pham / Duong Tran Anh / Vuong Nguyen Dinh

Sustainability, Vol 15, Iss 9021, p

2023 Band 9021

Abstract: In Southeast Vietnam, droughts have become more frequent, causing significant damage and impacting the region’s socio-economic development. Water shortages frequently affect the industrial and agricultural sectors in the area. This study aims to ... ...

Abstract	In Southeast Vietnam, droughts have become more frequent, causing significant damage and impacting the region’s socio-economic development. Water shortages frequently affect the industrial and agricultural sectors in the area. This study aims to calculate the water balance and the resilience of existing water resource allocations in the La Nga-Luy River basin based on two scenarios: (1) business-as-usual and (2) following a sustainable development approach. The MIKE NAM and MIKE HYDRO BASIN models were used for rainfall–runoff (R-R) and water balance modeling, respectively, and the Keetch–Byram Drought Index (KBDI) was used to estimate the magnitude of the droughts. The results identified areas within the Nga-Luy River basin where abnormally dry and moderate drought conditions are common, as well as subbasins, i.e., in the southeast and northeast, where severe and extreme droughts often prevail. It was also shown that the water demand for the irrigation of the winter–spring and summer–autumn crop life cycles could be fully met under abnormally dry conditions. This possibility decreases to 85–100% during moderate droughts, however. In contrast, 65% and 45–50% of the water demand for irrigation is met for the winter–spring and summer–autumn crop life cycles, respectively, during severe and extreme droughts. Furthermore, this study demonstrates that the water demand for irrigation could still be met 100% and 75–80% of the time during moderate, and extreme or severe droughts, respectively, through increased water use efficiency. This study could help managers to rationally regulate water in order to meet the agricultural sector’s needs in the region and reduce the damage and costs caused by droughts.
Schlagwörter	water allocation ; water use ; droughts ; climate change ; southeast Vietnam ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Thema/Rubrik (Code)	333
Sprache	Englisch
Erscheinungsdatum	2023-06-01T00:00:00Z
Verlag	MDPI AG
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

Volltext online

Volltext online

Zusatzmaterialien

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Artikel ; Online: Endothelial and inflammatory pathophysiology in dengue shock: New insights from a prospective cohort study in Vietnam.

McBride, Angela / Duyen, Huynh Thi Le / Vuong, Nguyen Lam / Tho, Phan Vinh / Tai, Luong Thi Hue / Phong, Nguyen Thanh / Ngoc, Nguyen Thanh / Yen, Lam Minh / Nhat, Phung Tran Huy / Vi, Tran Thuy / Llewelyn, Martin J / Thwaites, Louise / Hao, Nguyen Van / Yacoub, Sophie

PLoS neglected tropical diseases

2024 Band 18, Heft 3, Seite(n) e0012071

Abstract: Dengue shock (DS) is the most severe complication of dengue infection; endothelial hyperpermeability leads to profound plasma leakage, hypovolaemia and extravascular fluid accumulation. At present, the only treatment is supportive with intravenous fluid, ...

Abstract	Dengue shock (DS) is the most severe complication of dengue infection; endothelial hyperpermeability leads to profound plasma leakage, hypovolaemia and extravascular fluid accumulation. At present, the only treatment is supportive with intravenous fluid, but targeted endothelial stabilising therapies and host immune modulators are needed. With the aim of prioritising potential therapeutics, we conducted a prospective observational study of adults (≥16 years) with DS in Vietnam from 2019-2022, comparing the pathophysiology underlying circulatory failure with patients with septic shock (SS), and investigating the association of biomarkers with clinical severity (SOFA score, ICU admission, mortality) and pulmonary vascular leak (daily lung ultrasound for interstitial and pleural fluid). Plasma was collected at enrolment, 48 hours later and hospital discharge. We measured biomarkers of inflammation (IL-6, ferritin), endothelial activation (Ang-1, Ang-2, sTie-2, VCAM-1) and endothelial glycocalyx breakdown (hyaluronan, heparan sulfate, endocan, syndecan-1). We enrolled 135 patients with DS (median age 26, median SOFA score 7, 34 required ICU admission, 5 deaths), together with 37 patients with SS and 25 healthy controls. Within the DS group, IL-6 and ferritin were associated with admission SOFA score (IL-6: βeta0.70, p<0.001 & ferritin: βeta0.45, p<0.001), ICU admission (IL-6: OR 2.6, p<0.001 & ferritin: OR 1.55, p<0.001) and mortality (IL-6: OR 4.49, p = 0.005 & ferritin: OR 13.8, p = 0.02); both biomarkers discriminated survivors and non-survivors at 48 hours and all patients who died from DS had pre-mortem ferritin ≥100,000ng/ml. IL-6 most strongly correlated with severity of pulmonary vascular leakage (R = 0.41, p<0.001). Ang-2 correlated with pulmonary vascular leak (R = 0.33, p<0.001) and associated with SOFA score (β 0.81, p<0.001) and mortality (OR 8.06, p = 0.002). Ang-1 was associated with ICU admission (OR 1.6, p = 0.005) and mortality (OR 3.62, p = 0.006). All 4 glycocalyx biomarkers were positively associated with SOFA score, but only syndecan-1 was associated with ICU admission (OR 2.02, p<0.001) and mortality (OR 6.51, p<0.001). This study highlights the central role of hyperinflammation in determining outcomes from DS; the data suggest that anti-IL-1 and anti-IL-6 immune modulators and Tie2 agonists may be considered as candidates for therapeutic trials in severe dengue.
Mesh-Begriff(e)	Adult ; Humans ; Syndecan-1 ; Prospective Studies ; Vietnam/epidemiology ; Interleukin-6 ; Shock, Septic ; Biomarkers ; Severe Dengue ; Ferritins ; Prognosis ; Intensive Care Units ; Sepsis/complications
Chemische Substanzen	Syndecan-1 ; Interleukin-6 ; Biomarkers ; Ferritins (9007-73-2)
Sprache	Englisch
Erscheinungsdatum	2024-03-27
Erscheinungsland	United States
Dokumenttyp	Observational Study ; Journal Article
ZDB-ID	2429704-5
ISSN	1935-2735 ; 1935-2735
ISSN (online)	1935-2735
ISSN	1935-2735
DOI	10.1371/journal.pntd.0012071
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Details ▾
- Kostenpflichtig bestellen

Artikel: The impact of climate change on salinity intrusion and Pangasius (Pangasianodon Hypophthalmus) farming in the Mekong Delta, Vietnam

Trieu, Tran Thi Ngoc / Phong, Nguyen Thanh

Aquaculture international. 2015 Apr., v. 23, no. 2

2015

Abstract: The combined impact of sea level rise, changes in the upstream freshwater flow, and tidal regime on salinity intrusion that affects Pangasius (Pangasianodon hypophthalmus) farming in the Mekong Delta was assessed in this study. Salinity intrusion was ... ...

Abstract	The combined impact of sea level rise, changes in the upstream freshwater flow, and tidal regime on salinity intrusion that affects Pangasius (Pangasianodon hypophthalmus) farming in the Mekong Delta was assessed in this study. Salinity intrusion was simulated for the whole Mekong Delta by a 1D numerical model. The scenario derived from the SRES B2 climate change projection for Vietnam by the year 2100 (0.73 m of sea level rise and 29 % reduction of the Mekong River flow in the dry season). The simulated results suggest that the saline water will shift landward by 70–80 km which covers almost 63 % area of the Mekong Delta. Furthermore, it shows that the Pangasius farming area will be reduced by approximately 11 % with the shrinkage of the freshwater zone due to the salinity intrusion.
Schlagwörter	Pangasianodon hypophthalmus ; Pangasius ; climate change ; dry season ; farm area ; farming systems ; freshwater ; mathematical models ; river deltas ; saline water ; salinity ; sea level ; shrinkage ; Mekong River ; Vietnam
Sprache	Englisch
Erscheinungsverlauf	2015-04
Umfang	p. 523-534.
Erscheinungsort	Springer-Verlag
Dokumenttyp	Artikel
ZDB-ID	1176356-5
ISSN	1573-143X ; 0967-6120
ISSN (online)	1573-143X
ISSN	0967-6120
DOI	10.1007/s10499-014-9833-z
Datenquelle	NAL Katalog (AGRICOLA)

Volltext online

Zugriff für angemeldete ZB MED Nutzerinnen und Nutzer

Zusatzmaterialien

Verfügbar in ZB MED Bonn

Z 5774: Hefte anzeigen

Über subito bestellen

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾

Artikel ; Online: Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam.

Hung, Trinh Manh / Van Hao, Nguyen / Yen, Lam Minh / McBride, Angela / Dat, Vu Quoc / van Doorn, H Rogier / Loan, Huynh Thi / Phong, Nguyen Thanh / Llewelyn, Martin J / Nadjm, Behzad / Yacoub, Sophie / Thwaites, C Louise / Ahmed, Sayem / Van Vinh Chau, Nguyen / Turner, Hugo C

Frontiers in public health

2022 Band 10, Seite(n) 893200

Abstract: Background: Critically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle- ... ...

Abstract	Background: Critically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-income countries (LMICs). This study aims to investigate the direct-medical costs of key infectious disease (tetanus, sepsis, and dengue) patients admitted to ICU in a hospital in Ho Chi Minh City (HCMC), Vietnam, and explores how the costs and cost drivers can vary between the different diseases. Methods: We calculated the direct medical costs for patients requiring critical care for tetanus, dengue and sepsis. Costing data (stratified into different cost categories) were extracted from the bills of patients hospitalized to the adult ICU with a dengue, sepsis and tetanus diagnosis that were enrolled in three studies conducted at the Hospital for Tropical Diseases in HCMC from January 2017 to December 2019. The costs were considered from the health sector perspective. The total sample size in this study was 342 patients. Results: ICU care was associated with significant direct medical costs. For patients that did not require mechanical ventilation, the median total ICU cost per patient varied between US$64.40 and US$675 for the different diseases. The costs were higher for patients that required mechanical ventilation, with the median total ICU cost per patient for the different diseases varying between US$2,590 and US$4,250. The main cost drivers varied according to disease and associated severity. Conclusion: This study demonstrates the notable cost of ICU care in Vietnam and in similar LMIC settings. Future studies are needed to further evaluate the costs and economic burden incurred by ICU patients. The data also highlight the importance of evaluating novel critical care interventions that could reduce the costs of ICU care.
Mesh-Begriff(e)	Adult ; Cross Infection ; Dengue/therapy ; Humans ; Intensive Care Units ; Sepsis/therapy ; Tetanus/therapy ; Vietnam
Sprache	Englisch
Erscheinungsdatum	2022-06-20
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.893200
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel ; Online: Feasibility of establishing a rehabilitation programme in a Vietnamese intensive care unit.

Anh, Nguyen Thi Kim / Yen, Lam Minh / Nguyen, Nguyen Thanh / Nhat, Phung Tran Huy / Thuy, Tran Thi Diem / Phong, Nguyen Thanh / Tuyen, Pham Thi / Yen, Nguyen Hoang / Chambers, Mary / Hao, Nguyen Van / Rollinson, Thomas / Denehy, Linda / Thwaites, C Louise

PloS one

2021 Band 16, Heft 3, Seite(n) e0247406

Abstract: Increasing numbers of people are surviving critical illness throughout the world, but survivorship is associated with long-term disability. In high-income settings physical rehabilitation is commonly employed to counter this and improve outcomes. These ... ...

Abstract	Increasing numbers of people are surviving critical illness throughout the world, but survivorship is associated with long-term disability. In high-income settings physical rehabilitation is commonly employed to counter this and improve outcomes. These utilize highly-trained multidisciplinary teams and are unavailable and unaffordable in most low and middle income countries (LMICs). We aimed to design a sustainable intensive care unit (ICU) rehabilitation program and to evaluate its feasibility in a LMIC setting. In this project patients, care-givers and experts co-designed an innovative rehabilitation programme that can be delivered by non-expert ICU staff and family care-givers in a LMIC. We implemented this programme in adult patient with patients with tetanus at the Hospital for Tropical Diseases, Ho Chi Minh City over a 5-month period, evaluating the programme's acceptability, enablers and barriers. A 6-phase programme was designed, supported by written and video material. The programme was piloted in total of 30 patients. Rehabilitation was commenced a median 14 (inter quartile range (IQR) 10-18) days after admission. Each patient received a median of 25.5 (IQR 22.8-34.8) rehabilitation sessions out of a median 27 (22.8-35) intended (prescribed) sessions. There were no associated adverse events. Patients and staff found rehabilitation to be beneficial, enhanced relationships between carers, patients and staff and was deemed to be a positive step towards recovery and return to work. The main barrier was staff time. The programme was feasible for patients with tetanus and viewed positively by staff and participants. Staff time was identified as the major barrier to ongoing implementation.
Mesh-Begriff(e)	Asian Continental Ancestry Group ; Critical Illness ; Feasibility Studies ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Rehabilitation ; Vietnam
Sprache	Englisch
Erscheinungsdatum	2021-03-03
Erscheinungsland	United States
Dokumenttyp	Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0247406
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾
- Kostenpflichtig bestellen

Artikel ; Online: Tropical Asian mega‐delta ponds

Heather L. Moorhouse / Lucy R. Roberts / Suzanne McGowan / Virginia N. Panizzo / Philip Barker / Mashfiqus Salehin / Thu Nga Do / Phong Nguyen Thanh / Mohammad Feisal Rahman / Tuhin Ghosh / Sourav Das / Christopher Hackney / Jorge Salgado / Manoj Roy / Aftab Opel / Andrew C. G. Henderson / Andy R. G. Large

Geo: Geography and Environment, Vol 8, Iss 2, Pp n/a-n/a (2021)

Important and threatened socio‐ecological systems

2021

Abstract: Abstract This paper uses multimedia to showcase the narratives and lived experiences of those who live and work in tropical Asian mega‐deltas, and as such is the first journal article of its kind in the field of Regional Geography. Using videos, ... ...

Abstract	Abstract This paper uses multimedia to showcase the narratives and lived experiences of those who live and work in tropical Asian mega‐deltas, and as such is the first journal article of its kind in the field of Regional Geography. Using videos, photography and audio this paper describes the characteristics of ponds and their place in the intrinsically connected human‐environmental fabric of these delta regions. The aim is to bring to life descriptive inventories and provide greater weight in support of our conclusion that tropical Asian mega‐delta ponds are important and threatened systems. River deltas comprise just 1% of land cover worldwide but support the livelihoods of more than 500 million people. Delta research has historically focused on the major river channels and the socio‐ecological role of ponds has been overlooked despite their large number and surface area. Ponds are intrinsically linked to daily life (potable water, sanitation, bathing, washing), industry (aquaculture, agriculture) and the natural‐cultural heritage (religion, folklore) of deltas. In contrast to the larger river channels, ponds are likely to be significant stores and processors of nutrients, including carbon, and pollutants at annual to decadal scales, on account of their heavy anthropogenic use and smaller individual sizes. Consequently, they are severely polluted water sources and pose significant public health risks. In this review, we use case studies from three Asian mega‐deltas (the Red River Delta and the Mekong River Delta, Vietnam, and the Ganges‐Brahmaputra‐Meghna Delta, India and Bangladesh) to highlight the importance of Asian mega‐delta ponds as important socio‐ecological systems in their own right. We discuss future environmental challenges, knowledge gaps on the ecological function and biodiversity of these habitats, management and policy practices, and the capacity of ponds to achieve the UN Sustainable Development Goals.
Schlagwörter	Environmental sciences ; GE1-350 ; Geography (General) ; G1-922
Thema/Rubrik (Code)	333
Sprache	Englisch
Erscheinungsdatum	2021-07-01T00:00:00Z
Verlag	Wiley
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

Volltext online

Volltext online

Zusatzmaterialien

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Artikel ; Online: A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials.

BMC infectious diseases

2022 Band 22, Heft 1, Seite(n) 722

Abstract: Background: Dengue is a neglected tropical disease, for which no therapeutic agents have shown clinical efficacy to date. Clinical trials have used strikingly variable clinical endpoints, which hampers reproducibility and comparability of findings. We ... ...

Abstract	Background: Dengue is a neglected tropical disease, for which no therapeutic agents have shown clinical efficacy to date. Clinical trials have used strikingly variable clinical endpoints, which hampers reproducibility and comparability of findings. We investigated a delta modified Sequential Organ Failure Assessment (delta mSOFA) score as a uniform composite clinical endpoint for use in clinical trials investigating therapeutics for moderate and severe dengue. Methods: We developed a modified SOFA score for dengue, measured and evaluated its performance at baseline and 48 h after enrolment in a prospective observational cohort of 124 adults admitted to a tertiary referral hospital in Vietnam with dengue shock. The modified SOFA score included pulse pressure in the cardiovascular component. Binary logistic regression, cox proportional hazard and linear regression models were used to estimate association between mSOFA, delta mSOFA and clinical outcomes. Results: The analysis included 124 adults with dengue shock. 29 (23.4%) patients required ICU admission for organ support or due to persistent haemodynamic instability: 9/124 (7.3%) required mechanical ventilation, 8/124 (6.5%) required vasopressors, 6/124 (4.8%) required haemofiltration and 5/124 (4.0%) patients died. In univariate analyses, higher baseline and delta (48 h) mSOFA score for dengue were associated with admission to ICU, requirement for organ support and mortality, duration of ICU and hospital admission and IV fluid use. Conclusions: The baseline and delta mSOFA scores for dengue performed well to discriminate patients with dengue shock by clinical outcomes, including duration of ICU and hospital admission, requirement for organ support and death. We plan to use delta mSOFA as the primary endpoint in an upcoming host-directed therapeutic trial and investigate the performance of this score in other phenotypes of severe dengue in adults and children.
Mesh-Begriff(e)	Humans ; Intensive Care Units ; Multiple Organ Failure ; Organ Dysfunction Scores ; Prognosis ; Reproducibility of Results ; Retrospective Studies ; Severe Dengue ; Tertiary Care Centers
Sprache	Englisch
Erscheinungsdatum	2022-09-03
Erscheinungsland	England
Dokumenttyp	Journal Article ; Observational Study
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-022-07705-8
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel: Urinary catecholamine excretion, cardiovascular variability, and outcomes in tetanus.

Du, Duc Hong / Hao, Nguyen Quan Nhu / Van Hao, Nguyen / Thanh, Tran Tan / Loan, Huynh Thi / Yen, Lam Minh / Thuy, Tran Thi Diem / Thuy, Duong Bich / Nguyen, Nguyen Thanh / Dung, Nguyen Thi Phuong / Kestelyn, Evelyne / Duong, Ha Thi Hai / Phong, Nguyen Thanh / Tuyen, Pham Thi / Phu, Nguyen Hoan / Nghia, Ho Dang Trung / Hanh, Bui Thi Bich / Oanh, Pham Kieu Nguyet / Tho, Phan Vinh /

Nhat, Phung Tran Huy / Khanh, Phan Nguyen Quoc / Wyncoll, Duncan / Day, Nicholas P J / Van Vinh Chau, Nguyen / van Doorn, H Rogier / Van Tan, Le / Geskus, Ronald B / Thwaites, C Louise

Tropical medicine and health

2023 Band 51, Heft 1, Seite(n) 20

Abstract: Severe tetanus is characterized by muscle spasm and cardiovascular system disturbance. The pathophysiology of muscle spasm is relatively well understood and involves inhibition of central inhibitory synapses by tetanus toxin. That of cardiovascular ... ...

Abstract	Severe tetanus is characterized by muscle spasm and cardiovascular system disturbance. The pathophysiology of muscle spasm is relatively well understood and involves inhibition of central inhibitory synapses by tetanus toxin. That of cardiovascular disturbance is less clear, but is believed to relate to disinhibition of the autonomic nervous system. The clinical syndrome of autonomic nervous system dysfunction (ANSD) seen in severe tetanus is characterized principally by changes in heart rate and blood pressure which have been linked to increased circulating catecholamines. Previous studies have described varying relationships between catecholamines and signs of ANSD in tetanus, but are limited by confounders and assays used. In this study, we aimed to perform detailed characterization of the relationship between catecholamines (adrenaline and noradrenaline), cardiovascular parameters (heart rate and blood pressure) and clinical outcomes (ANSD, mechanical ventilation required, and length of intensive care unit stay) in adults with tetanus, as well as examine whether intrathecal antitoxin administration affected subsequent catecholamine excretion. Noradrenaline and adrenaline were measured by ELISA from 24-h urine collections taken on day 5 of hospitalization in 272 patients enrolled in a 2 × 2 factorial-blinded randomized controlled trial in a Vietnamese hospital. Catecholamine results measured from 263 patients were available for analysis. After adjustment for potential confounders (i.e., age, sex, intervention treatment, and medications), there were indications of non-linear relationships between urinary catecholamines and heart rate. Adrenaline and noradrenaline were associated with subsequent development of ANSD, and length of ICU stay.
Sprache	Englisch
Erscheinungsdatum	2023-03-30
Erscheinungsland	Japan
Dokumenttyp	Journal Article
ZDB-ID	2209835-5
ISSN	1349-4147 ; 1348-8945
ISSN (online)	1349-4147
ISSN	1348-8945
DOI	10.1186/s41182-023-00512-0
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Details ▾
- Kostenpflichtig bestellen

Artikel: Wearable devices for remote monitoring of hospitalized patients with COVID-19 in Vietnam.

Chau, Nguyen Van Vinh / Trung, Truong Ngoc / Khanh, Phan Nguyen Quoc Khanh / Nhat, Phung Tran Huy / Van, Hoang Minh Tu / Hai, Ho Bich / Thuy, Duong Bich / Tung, Nguyen Le Nhu / Khoa, Dao Bach / Vien, Tran Thi Dong / Hao, Nguyen Van / Oanh, Pham Kieu Ngyuyet / Khoa, Tran Dang / Phong, Nguyen Thanh / Nguyen, Nguyen Thanh / Huynh, Julie / Walker, Timothy M / Van Nuil, Jennifer / An, Luu Phuoc /

McKnight, Jacob / Toan, Le Mau / Tan, Le Van / Dung, Nguyen Thanh / Truong, Nguyen Thanh / Thwaites, C Louise

Wellcome open research

2023 Band 7, Seite(n) 257

Abstract: Patients with severe COVID-19 disease require monitoring with pulse oximetry as a minimal requirement. In many low- and middle- income countries, this has been challenging due to lack of staff and equipment. Wearable pulse oximeters potentially offer an ... ...

Abstract	Patients with severe COVID-19 disease require monitoring with pulse oximetry as a minimal requirement. In many low- and middle- income countries, this has been challenging due to lack of staff and equipment. Wearable pulse oximeters potentially offer an attractive means to address this need, due to their low cost, battery operability and capacity for remote monitoring. Between July and October 2021, Ho Chi Minh City experienced its first major wave of SARS-CoV-2 infection, leading to an unprecedented demand for monitoring in hospitalized patients. We assess the feasibility of a continuous remote monitoring system for patients with COVID-19 under these circumstances as we implemented 2 different systems using wearable pulse oximeter devices in a stepwise manner across 4 departments.
Sprache	Englisch
Erscheinungsdatum	2023-06-20
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	2398-502X
ISSN	2398-502X
DOI	10.12688/wellcomeopenres.18026.2
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Zusatzmaterialien

Über subito bestellen

Fernleihe an ZB MED

Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Details ▾
- Kostenpflichtig bestellen

Zum Seitenanfang

Ihre letzten Suchen

Volltext online

Zusatzmaterialien

Kategorien

Fernleihe an ZB MED

Volltext online

Zusatzmaterialien

Kategorien

Fernleihe an ZB MED

Zusatzmaterialien

Kategorien

Über subito bestellen

Volltext online

Zusatzmaterialien

Kategorien

Verfügbar in ZB MED Bonn

Über subito bestellen

Fernleihe an ZB MED

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Fernleihe an ZB MED

Volltext online

Zusatzmaterialien

Kategorien

Fernleihe an ZB MED

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Zusatzmaterialien

Kategorien

Über subito bestellen

Fernleihe an ZB MED