Article: Incidence, and natural history of inflammatory bowel disease in Castilla y León: Prospective and multicenter epidemiological study.
Gastroenterologia y hepatologia
2022 Volume 46, Issue 2, Page(s) 102–108
Abstract: Introduction: The incidence of inflammatory bowel disease (IBD) is increasing worldwide.: Objectives: To evaluate the incidence of IBD in Castilla y León describing clinical characteristics of the patients at diagnosis, the type of treatment received ...
| Title translation | Incidencia e historia natural de la enfermedad inflamatoria intestinal en Castilla y León: estudio prospectivo, multicéntrico y poblacional. |
|---|---|
| Abstract | Introduction: The incidence of inflammatory bowel disease (IBD) is increasing worldwide. Objectives: To evaluate the incidence of IBD in Castilla y León describing clinical characteristics of the patients at diagnosis, the type of treatment received and their clinical course during the first year. Materials and methods: Prospective, multicenter and population-based incidence cohort study. Patients aged >18 years diagnosed during 2017 with IBD (Crohn's disease [CD], ulcerative colitis [UC] and indeterminate colitis [IC]) were included from 8 hospitals in Castilla y León. Epidemiological, clinical, and therapeutic variables were registered. The global incidence and disease incidence were calculated. Results: 290 patients were diagnosed with IBD (54.5% UC, 45.2% CD, and 0.3% IC), with a median follow-up of 9 months (range 8-11). The incidence rate of IBD in Castilla y Leon in 2017 was 16.6 cases per 10,000 inhabitants-year (9/10 Conclusions: The incidence of patients with UC in our population increases while the incidence of patients with CD remains stable. Patients with CD present a worse natural history of the disease (use of corticosteroids, immunomodulatory therapy, biological therapy and surgery) compared to patients with UC in the first year of follow-up. |
| MeSH term(s) | Humans ; Incidence ; Prospective Studies ; Cohort Studies ; Inflammatory Bowel Diseases/epidemiology ; Colitis, Ulcerative/epidemiology ; Colitis, Ulcerative/therapy ; Colitis, Ulcerative/diagnosis ; Crohn Disease/diagnosis ; Colitis ; Adrenal Cortex Hormones/therapeutic use |
| Chemical Substances | Adrenal Cortex Hormones |
| Language | Spanish |
| Publishing date | 2022-05-13 |
| Publishing country | Spain |
| Document type | Multicenter Study ; Journal Article |
| ZDB-ID | 632502-6 |
| ISSN | 0210-5705 |
| ISSN | 0210-5705 |
| DOI | 10.1016/j.gastrohep.2022.04.002 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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