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  1. Article ; Online: Poor sleep quality, impaired cardiac autonomic control, and metabolic syndrome: a tricky relationship?

    Roche, Frédéric / Pichot, Vincent / Garet, Martin / Berger, Mathieu

    Sleep

    2023  Volume 46, Issue 5

    MeSH term(s) Humans ; Metabolic Syndrome/complications ; Sleep Quality ; Heart ; Autonomic Nervous System ; Sleep Initiation and Maintenance Disorders ; Heart Rate ; Sleep
    Language English
    Publishing date 2023-02-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsad022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1475: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Why, when and how to assess autonomic nervous system maturation in neonatal care units: A practical overview.

    Patural, Hugues / Pichot, Vincent / Roche, Frédéric / Giraud, Antoine

    Neurophysiologie clinique = Clinical neurophysiology

    2023  Volume 53, Issue 2, Page(s) 102855

    Abstract: The evaluation of the autonomic reactivity of newborns by heart rate variability (HRV) analysis is a simple and essential aid to identifying pathological situations of dysautonomia. Thanks to this relatively simple and reproducible analytic tool, the ... ...

    Abstract The evaluation of the autonomic reactivity of newborns by heart rate variability (HRV) analysis is a simple and essential aid to identifying pathological situations of dysautonomia. Thanks to this relatively simple and reproducible analytic tool, the pediatrician can identify and target children at high risk of life-threatening events, i.e., those with insufficient intrinsic capacity for cardiorespiratory self-regulation, who should benefit from close cardiorespiratory monitoring. Different mathematical algorithms integrate delayed or real-time variations in the length of the RR interval to better understand the state of autonomic maturation of the newborn. HRV analysis, as a non-invasive tool for assessing autonomic balance, is essential to assess the functioning of the autonomic nervous system and, more specifically, parasympathetic/sympathetic balance. Despite many recognized diagnostic and therapeutic implications, its application to neonatal medicine is not yet well understood.
    MeSH term(s) Child ; Humans ; Infant, Newborn ; Autonomic Nervous System ; Heart Rate/physiology
    Language English
    Publishing date 2023-03-23
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 639421-8
    ISSN 1769-7131 ; 0987-7053
    ISSN (online) 1769-7131
    ISSN 0987-7053
    DOI 10.1016/j.neucli.2023.102855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1049: Show issues Location:
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  3. Article: CVRanalysis

    Pichot, Vincent / Corbier, Christophe / Chouchou, Florian / Barthélémy, Jean-Claude / Roche, Frédéric

    Frontiers in physiology

    2024  Volume 14, Page(s) 1224440

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1224440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Heart Rate Variability Analysis to Evaluate Autonomic Nervous System Maturation in Neonates: An Expert Opinion.

    Patural, Hugues / Franco, Patricia / Pichot, Vincent / Giraud, Antoine

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 860145

    Abstract: While heart rate variability (HRV) is a relevant non-invasive tool to assess the autonomic nervous system (ANS) functioning with recognized diagnostic and therapeutic implications, the lack of knowledge on its interest in neonatal medicine is certain. ... ...

    Abstract While heart rate variability (HRV) is a relevant non-invasive tool to assess the autonomic nervous system (ANS) functioning with recognized diagnostic and therapeutic implications, the lack of knowledge on its interest in neonatal medicine is certain. This review aims to briefly describe the algorithms used to decompose variations in the length of the RR interval and better understand the physiological autonomic maturation data of the newborn. Assessing newborns' autonomous reactivity can identify dysautonomia situations and discriminate children with a high risk of life-threatening events, which should benefit from cardiorespiratory monitoring at home. Targeted monitoring of HRV should provide an objective reflection of the newborn's intrinsic capacity for cardiorespiratory self-regulation.
    Language English
    Publishing date 2022-04-21
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.860145
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  5. Article ; Online: Obstructive sleep apnea/hypopnea syndrome phenotypes after night sleep recordings: how to get to precision medicine in 2021.

    Roche, Frédéric / Mouhli, Lytissia / Pichot, Vincent / Celle, Sébastien

    Sleep

    2021  Volume 44, Issue 7

    MeSH term(s) Humans ; Phenotype ; Polysomnography ; Precision Medicine ; Sleep ; Sleep Apnea, Obstructive
    Language English
    Publishing date 2021-07-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsab154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1475: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Obesity related to metabolic syndrome: comparison of obesity indicators in an older french population.

    Ntougou Assoumou, Hourfil-Gabin / Pichot, Vincent / Barthelemy, Jean-Claude / Celle, Sébastien / Garcin, Arnauld / Thomas, Thierry / Roche, Frédéric

    Diabetology & metabolic syndrome

    2023  Volume 15, Issue 1, Page(s) 98

    Abstract: Objectives: Metabolic syndrome (MS) represents a cluster of metabolic abnormalities. Insulin resistance is a major component of the syndrome. We analyze in this study the relationship between body fat composition and MS in comparison to usual obesity ... ...

    Abstract Objectives: Metabolic syndrome (MS) represents a cluster of metabolic abnormalities. Insulin resistance is a major component of the syndrome. We analyze in this study the relationship between body fat composition and MS in comparison to usual obesity indicators in an older adult population.
    Design: The PROgnostic indicator OF cardiovascular and cerebrovascular events (PROOF) study is a prospective longitudinal community cohort study among the inhabitants of Saint-Etienne, France.
    Methods: The study is a cohort study of 1011 subjects, mean age 65.6 ± 0.8 years old at inclusion, recruited from the electoral list of the town in 2000. Among them, 806 subjects realized a Dual-energy X-ray absorptiometry (DXA) used to evaluate body fat and lean mass repartition. We evaluate biological metabolic parameters according to usual techniques. The indices of obesity were calculated according to standard formula. MS presence and its components were simultaneously evaluated.
    Results: All obesity parameters were significantly higher (p < 0.0001) in subjects suffering metabolic syndrome as compared to those without. Body fat index (BFI) presented a stronger correlation to total fat mass, trunk fat mass and body adiposity index (BAI). The correlations between body indices and metabolic components showed that body mass index (BMI) and waist circumference were more strongly associated with BFI as compared to BAI and total fat mass. According to logistic regression analysis, only the waist-hip ratio (WHR) demonstrated a significant association with MS severity (p < 0.0001).
    Conclusions: Among the obesity indices, BFI and BAI represented the best indicators to characterize global obesity while WHR only is highly predictive of metabolic syndrome presence and severity. The BAI indicator is an alternative for measuring obesity. Comparison of long-term impact of such markers on cardiovascular morbidity and mortality is now questioned.
    Language English
    Publishing date 2023-05-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2518786-7
    ISSN 1758-5996
    ISSN 1758-5996
    DOI 10.1186/s13098-023-01078-x
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  7. Article: Internight Variability of Apnea-Hypopnea Index in Obstructive Sleep Apnea Using Ambulatory Polysomnography.

    Sforza, Emilia / Roche, Frédéric / Chapelle, Céline / Pichot, Vincent

    Frontiers in physiology

    2019  Volume 10, Page(s) 849

    Abstract: Rationale: ...

    Abstract Rationale:
    Language English
    Publishing date 2019-07-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2019.00849
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  8. Article: Determinants of Nocturnal Cardiovascular Variability and Heart Rate Arousal Response in Restless Legs Syndrome (RLS)/Periodic Limb Movements (PLMS).

    Sforza, Emilia / Roche, Frédéric / Pichot, Vincent

    Journal of clinical medicine

    2019  Volume 8, Issue 10

    Abstract: Recent studies have suggested that restless legs syndrome is associated with an increased prevalence of cardiovascular diseases mediated by sympathetic activation occurring during periodic limb movements. The aim of this study was to establish which ... ...

    Abstract Recent studies have suggested that restless legs syndrome is associated with an increased prevalence of cardiovascular diseases mediated by sympathetic activation occurring during periodic limb movements. The aim of this study was to establish which factors affect the degree of sympathetic activation during the basal condition and during periodic limb movements that may contribute to increased vascular risk. Fifty untreated restless legs syndrome patients aged 62.6 ± 11.1 y, free of cardiovascular diseases, were examined. Heart rate variability was calculated during wakefulness and all sleep stages, during periods with and without periodic limb movements. Heart rate changes before and after periodic limb movement onset were analyzed to assess the arousal response to periodic limb movements. Both analyses took into account the effects of age, gender, periodic limb movement duration, periodic limb movement index, periodic limb movement interval and periodicity, and magnitude of muscular activity (electromyogram power). Compared to periods without periodic limb movements, a significant increase in sympathetic activity occurred in periods with periodic limb movements, independent of age, sex and periodic limb movement characteristics. Data obtained from the cardiac arousal response to periodic limb movements showed that electromyogram power is the factor affecting sympathetic tonus. These results suggest that other factors, such as electromyogram power and individual susceptibility, should be considered in the assessment of the vascular risk related to restless legs syndrome.
    Language English
    Publishing date 2019-10-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm8101619
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  9. Article ; Online: Impaired post-sleep apnea autonomic arousals in patients with drug-resistant epilepsy.

    Ricordeau, François / Chouchou, Florian / Pichot, Vincent / Roche, Frédéric / Petitjean, Thierry / Gormand, Frédéric / Bastuji, Hélène / Charbonnier, Eléna / Le Cam, Pierre / Stauffer, Emeric / Rheims, Sylvain / Peter-Derex, Laure

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    2024  Volume 160, Page(s) 1–11

    Abstract: Objective: Sudden and unexpected deaths in epilepsy (SUDEP) pathophysiology may involve an interaction between respiratory dysfunction and sleep/wake state regulation. We investigated whether patients with epilepsy exhibit impaired sleep apnea-related ... ...

    Abstract Objective: Sudden and unexpected deaths in epilepsy (SUDEP) pathophysiology may involve an interaction between respiratory dysfunction and sleep/wake state regulation. We investigated whether patients with epilepsy exhibit impaired sleep apnea-related arousals.
    Methods: Patients with drug-resistant (N = 20) or drug-sensitive (N = 20) epilepsy and obstructive sleep apnea, as well as patients with sleep apnea but without epilepsy (controls, N = 20) were included. We explored (1) the respiratory arousal threshold based on nadir oxygen saturation, apnea-hypopnea index, and fraction of hypopnea among respiratory events; (2) the cardiac autonomic response to apnea/hypopnea quantified as percentages of changes from the baseline in RR intervals (RRI), high (HF) and low (LF) frequency powers, and LF/HF.
    Results: The respiratory arousal threshold did not differ between groups. At arousal onset, RRI decreased (-9.42%) and LF power (179%) and LF/HF ratio (190%) increased. This was followed by an increase in HF power (118%), p < 0.05. The RRI decrease was lower in drug-resistant (-7.40%) than in drug-sensitive patients (-9.94%) and controls (-10.91%), p < 0.05. LF and HF power increases were higher in drug-resistant (188%/126%) than in drug-sensitive patients (172%/126%) and controls (177%/115%), p < 0.05.
    Conclusions: Cardiac reactivity following sleep apnea is impaired in drug-resistant epilepsy.
    Significance: This autonomic dysfunction might contribute to SUDEP pathophysiology.
    MeSH term(s) Humans ; Sudden Unexpected Death in Epilepsy ; Polysomnography ; Autonomic Nervous System ; Sleep Apnea Syndromes/diagnosis ; Drug Resistant Epilepsy/diagnosis ; Arousal/physiology ; Heart Rate/physiology
    Language English
    Publishing date 2024-02-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1463630-x
    ISSN 1872-8952 ; 0921-884X ; 1388-2457
    ISSN (online) 1872-8952
    ISSN 0921-884X ; 1388-2457
    DOI 10.1016/j.clinph.2024.02.003
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    Ui II Zs.140: Show issues Location:
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  10. Article: Leukoaraiosis and Gray Matter Volume Alteration in Older Adults: The PROOF Study.

    Celle, Sébastien / Boutet, Claire / Annweiler, Cédric / Ceresetti, Romain / Pichot, Vincent / Barthélémy, Jean-Claude / Roche, Frédéric

    Frontiers in neuroscience

    2022  Volume 15, Page(s) 747569

    Abstract: Background and Purpose: ...

    Abstract Background and Purpose:
    Language English
    Publishing date 2022-01-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2021.747569
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