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  1. Article: Life after stillbirth: a father's story.

    Pidgeon, Colin

    RCM midwives : the official journal of the Royal College of Midwives

    2007  Volume 10, Issue 6, Page(s) 288–289

    MeSH term(s) Adaptation, Psychological ; Adult ; Attitude to Death ; Father-Child Relations ; Fathers/psychology ; Grief ; Humans ; Infant, Newborn ; Male ; Midwifery/methods ; Narration ; Nurse's Role ; Stillbirth/psychology
    Language English
    Publishing date 2007-06
    Publishing country England
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Role of Wrist Arthroscopy in Juvenile Inflammatory Arthritis.

    Ishwar, Mahalakshmi / Lindau, Tommy R / Johnson, Karl / Pidgeon, Claire / Jester, Andrea / Coles, William / Oestreich, Kerstin

    Journal of wrist surgery

    2022  Volume 11, Issue 5, Page(s) 376–382

    Abstract: Background and ... ...

    Abstract Background and Purposes
    Language English
    Publishing date 2022-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2678060-4
    ISSN 2163-3924 ; 2163-3916
    ISSN (online) 2163-3924
    ISSN 2163-3916
    DOI 10.1055/s-0042-1743448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Formation of multilayered vesicles from water/organic-solvent (w/o) emulsions: theory and practice.

    Pidgeon, C / Hunt, A H / Dittrich, K

    Pharmaceutical research

    2013  Volume 3, Issue 1, Page(s) 23–34

    Abstract: Multilayered liposome (MLV) formation from water/organic-solvent (W/O) emulsions was studied. A fundamental liposome population parameter, the E(ratio), was defined and used to estimate the bilayer number and water spacing in MLV liposomes. MLVs prepared ...

    Abstract Multilayered liposome (MLV) formation from water/organic-solvent (W/O) emulsions was studied. A fundamental liposome population parameter, the E(ratio), was defined and used to estimate the bilayer number and water spacing in MLV liposomes. MLVs prepared from W/O emulsions have optimum drug entrapment at an emulsion-lipid/emulsion-water ratio of ∼0.33. Drug entrapment is typically 50 to 65% under these optimal conditions.
    Language English
    Publishing date 2013-11-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 843063-9
    ISSN 1573-904X ; 0724-8741 ; 0739-0742
    ISSN (online) 1573-904X
    ISSN 0724-8741 ; 0739-0742
    DOI 10.1023/A:1016316730560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1937: Show issues Location:
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  4. Article ; Online: The multi-photon induced Fano effect.

    Litvinenko, K L / Le, Nguyen H / Redlich, B / Pidgeon, C R / Abrosimov, N V / Andreev, Y / Huang, Zhiming / Murdin, B N

    Nature communications

    2021  Volume 12, Issue 1, Page(s) 454

    Abstract: The ordinary Fano effect occurs in many-electron atoms and requires an autoionizing state. With such a state, photo-ionization may proceed via pathways that interfere, and the characteristic asymmetric resonance structures appear in the continuum. Here ... ...

    Abstract The ordinary Fano effect occurs in many-electron atoms and requires an autoionizing state. With such a state, photo-ionization may proceed via pathways that interfere, and the characteristic asymmetric resonance structures appear in the continuum. Here we demonstrate that Fano structure may also be induced without need of auto-ionization, by dressing the continuum with an ordinary bound state in any atom by a coupling laser. Using multi-photon processes gives complete, ultra-fast control over the interference. We show that a line-shape index q near unity (maximum asymmetry) may be produced in hydrogenic silicon donors with a relatively weak beam. Since the Fano lineshape has both constructive and destructive interference, the laser control opens the possibility of state-selective detection with enhancement on one side of resonance and invisibility on the other. We discuss a variety of atomic and molecular spectroscopies, and in the case of silicon donors we provide a calculation for a qubit readout application.
    Language English
    Publishing date 2021-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-20534-0
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  5. Article ; Online: The pathophysiology and pharmacological treatment of Huntington disease.

    Pidgeon, Connie / Rickards, Hugh

    Behavioural neurology

    2012  Volume 26, Issue 4, Page(s) 245–253

    Abstract: Introduction: Huntington disease (HD) is a progressive neurodegenerative condition characterised by motor, cognitive and behavioural dysfunction, and has an autosomal dominant mode of inheritance. As there is currently no treatment to delay progression ... ...

    Abstract Introduction: Huntington disease (HD) is a progressive neurodegenerative condition characterised by motor, cognitive and behavioural dysfunction, and has an autosomal dominant mode of inheritance. As there is currently no treatment to delay progression of the disease, pharmacological intervention is aimed at symptomatic relief.
    Methods: We set out to assess the current evidence on the pharmacological treatment of motor and non-motor symptoms in HD by carrying out a systematic literature review across five large scientific databases.
    Results: The search generated 23 original studies meeting our search criteria. Studies on the following drug classes were obtained: dopamine (DA) depleting agents, neuroleptics, anti-glutamatergic agents, acetylcholinesterase inhibitors, GABA agonists, cannabinoids, antidepressants and potential neuroprotective agents. Tetrabenazine (TBZ), a DA depleting agent, was the only pharmacotherapy shown to have a clinically meaningful, statistically significant effect on chorea. The majority of the reviewed studies focussed on the treatment of motor symptoms of HD.
    Discussion: Overall, the evidence base for the pharmacological management of HD is poor. There is a clear need for future high quality randomised controlled trials on the symptomatic treatment of HD, particularly on the pharmacotherapy of non-motor symptoms of HD.
    MeSH term(s) Antidepressive Agents/therapeutic use ; Antipsychotic Agents/therapeutic use ; Basal Ganglia/drug effects ; Basal Ganglia/physiopathology ; Cannabinoids/therapeutic use ; Cholinesterase Inhibitors/therapeutic use ; Excitatory Amino Acid Antagonists/therapeutic use ; GABA Agonists/therapeutic use ; Humans ; Huntington Disease/drug therapy ; Huntington Disease/physiopathology ; Neuroprotective Agents/therapeutic use ; Tetrabenazine/therapeutic use
    Chemical Substances Antidepressive Agents ; Antipsychotic Agents ; Cannabinoids ; Cholinesterase Inhibitors ; Excitatory Amino Acid Antagonists ; GABA Agonists ; Neuroprotective Agents ; Tetrabenazine (Z9O08YRN8O)
    Language English
    Publishing date 2012-06-19
    Publishing country Netherlands
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1001896-7
    ISSN 1875-8584 ; 0953-4180
    ISSN (online) 1875-8584
    ISSN 0953-4180
    DOI 10.3233/BEN-2012-120267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2574: Show issues Location:
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  6. Article: Solid phase membrane mimetics: immobilized artificial membranes.

    Pidgeon, C

    Enzyme and microbial technology

    1990  Volume 12, Issue 2, Page(s) 149–150

    Abstract: The studies discussed demonstrate the importance of developing rapid methods to purify membrane proteins and also quantitate binding events between cell membranes and biomolecules. Traditional equilibrium methods are experimentally very difficult because ...

    Abstract The studies discussed demonstrate the importance of developing rapid methods to purify membrane proteins and also quantitate binding events between cell membranes and biomolecules. Traditional equilibrium methods are experimentally very difficult because of long equilibration times, peptide aggregation, and the need to make several measurements to obtain a single binding constant. We are developing chromatographic methods to measure binding constants between membranes and biomolecules by using solid phase membrane mimetics. Solid phase binding assays are well established for reactions that typically occur in solution, whereas for reactions that require a membrane environment, no solid phase assay exists. Solid phase membrane mimetics have the potential of filling this gap.
    MeSH term(s) Membrane Fusion ; Membrane Proteins/physiology ; Membranes, Artificial ; Models, Biological
    Chemical Substances Membrane Proteins ; Membranes, Artificial
    Language English
    Publishing date 1990-02
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 423729-8
    ISSN 1879-0909 ; 0141-0229
    ISSN (online) 1879-0909
    ISSN 0141-0229
    DOI 10.1016/0141-0229(90)90090-d
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    Zs.B 2182: Show issues Location:
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  7. Article: Age related outcome in acute subdural haematoma following traumatic head injury.

    Hanif, S / Abodunde, O / Ali, Z / Pidgeon, C

    Irish medical journal

    2009  Volume 102, Issue 8, Page(s) 255–257

    Abstract: Acute subdural haematoma (ASDH) is one of the conditions most strongly associated with severe brain injury. Reports prior to 1980 describe overall mortality rates for acute subdural haematomas (SDH's) ranging from 40% to 90% with poor outcomes observed ... ...

    Abstract Acute subdural haematoma (ASDH) is one of the conditions most strongly associated with severe brain injury. Reports prior to 1980 describe overall mortality rates for acute subdural haematomas (SDH's) ranging from 40% to 90% with poor outcomes observed in all age groups. Recently, improved results have been reported with rapid diagnosis and surgical treatment. The elderly are predisposed to bleeding due to normal cerebral atrophy related to aging, stretching the bridging veins from the dura. Prognosis in ASDH is associated with age, time from injury to treatment, presence of pupillary abnormalities, Glasgow Coma Score (GCS) or motor score on admission, immediate coma or lucid interval, computerized tomography findings (haematoma volume, degree of midline shift, associated intradural lesion, compression of basal cisterns), post-operative intracranial pressure and type of surgery. Advancing age is known to be a determinant of outcome in head injury. We present the results of a retrospective study carried out in Beaumont Hospital, Dublin, Ireland's national neurosurgical centre. The aim of our study was to examine the impact of age on outcome in patients with ASDH following severe head injury. Only cases with acute subdural haematoma requiring surgical evacuation were recruited. Mortality was significantly higher in older patients (50% above 70 years, 25.6% between 40 and 70 years and 26% below 40 years). Overall poor outcome (defined as Glasgow outcome scores 3-5) was also higher in older patients; 74.1% above 70 years, 48% between 40 and 70 years and 30% below 40 years. Poor outcome in traumatic acute subdural haematoma is higher in elderly patients even after surgical intervention.
    MeSH term(s) Adult ; Age Factors ; Aged ; Brain Injuries/complications ; Female ; Glasgow Coma Scale ; Health Status Indicators ; Hematoma, Subdural, Acute/diagnosis ; Hematoma, Subdural, Acute/etiology ; Hematoma, Subdural, Acute/mortality ; Hematoma, Subdural, Acute/surgery ; Humans ; Ireland ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2009-09
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 148: Show issues Location:
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  8. Article: Role of Wrist Arthroscopy in Juvenile Inflammatory Arthritis

    Ishwar, Mahalakshmi / Lindau, Tommy R. / Johnson, Karl / Pidgeon, Claire / Jester, Andrea / Coles, William / Oestreich, Kerstin

    Journal of Wrist Surgery

    2022  Volume 11, Issue 05, Page(s) 376–382

    Abstract: Background and Purposes: The wrist is the fourth most common joint to be involved in juvenile inflammatory arthritis (JIA), which is a common rheumatological condition affecting children. Wrist arthroscopy is well established in rheumatoid arthritis, ... ...

    Abstract Background and Purposes: The wrist is the fourth most common joint to be involved in juvenile inflammatory arthritis (JIA), which is a common rheumatological condition affecting children. Wrist arthroscopy is well established in rheumatoid arthritis, but remains unexplored in JIA. The aim of this study is to investigate the role of wrist arthroscopy in JIA, with focus on those who are refractory to medical management.
    Methods: This is a prospective observational study, including consecutive patients with JIA undergoing arthroscopy between January 2016 and December 2020. Those over the age of 18 years and those with other rheumatological diagnoses were excluded. Data including pre-, intra-, and postoperative variables, demographics, and patient-reported outcomes were collated and are reported using standard measures.
    Results: A total of 15 patients underwent arthroscopy ( n  = 20 wrists). Synovitis was noted in all wrists on arthroscopy and synovectomy was performed in all cases. Other procedures were performed as indicated during the procedure. The median follow-up duration was 11.3 (interquartile range [IQR] 8.1–24.2) months. Median reduction of 4 (IQR 2.25–6) points on the Visual Analogue Score for pain on loading was noted postoperatively. Grip strength was improved in n  = 11/20 wrists and functional improvement was noted in n  = 18/20 wrists. Restriction of range of motion was achieved with a shrinkage procedure in patients with hypermobile joints. There were no postoperative complications, and no patients were lost to follow-up.
    Conclusion: In experienced hands, wrist arthroscopy is feasible, safe, and efficacious in the management of JIA, among patients who are refractory to medical management.
    Level of Evidence: This is a Level II study.
    Keywords wrist ; arthroscopy ; juvenile inflammatory arthritis ; pain ; synovitis ; synovectomy ; range of motion
    Language English
    Publishing date 2022-03-08
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2678060-4
    ISSN 2163-3924 ; 2163-3916 ; 2163-3924
    ISSN (online) 2163-3924
    ISSN 2163-3916 ; 2163-3924
    DOI 10.1055/s-0042-1743448
    Database Thieme publisher's database

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  9. Article: Clip slippage.

    Pidgeon, C N

    Journal of neurosurgery

    2001  Volume 95, Issue 4, Page(s) 725

    MeSH term(s) Alloys ; Equipment Failure ; Humans ; Intracranial Aneurysm/surgery ; Surgical Instruments/adverse effects ; Titanium
    Chemical Substances Alloys ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2001-10
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/jns.2001.95.4.0725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Tutorials for the biomedical sciences

    Pidgeon, C

    animations, simulations, and calculations using Mathematica

    1996  

    Author's details edited by Charles Pidgeon
    MeSH term(s) Software ; Biomedical Technology ; Chemistry Techniques, Analytical
    Language English
    Size xxvii, 300 p. :, ill. +
    Publisher VCH Publishers
    Publishing place New York
    Document type Book
    Accompanying material 2 computer disks (3 1/2 in.)
    ISBN 9781560819288 ; 1560819286
    Database Catalogue of the US National Library of Medicine (NLM)

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