LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: From one to many

    Pierre Bessière / Romain Volmer

    PLoS Pathogens, Vol 17, Iss 9, p e

    The within-host rise of viral variants.

    2021  Volume 1009811

    Keywords Immunologic diseases. Allergy ; RC581-607 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Computer simulations of coupled idiosyncrasies in speech perception and speech production with COSMO, a perceptuo-motor Bayesian model of speech communication.

    Marie-Lou Barnaud / Jean-Luc Schwartz / Pierre Bessière / Julien Diard

    PLoS ONE, Vol 14, Iss 1, p e

    2019  Volume 0210302

    Abstract: The existence of a functional relationship between speech perception and production systems is now widely accepted, but the exact nature and role of this relationship remains quite unclear. The existence of idiosyncrasies in production and in perception ... ...

    Abstract The existence of a functional relationship between speech perception and production systems is now widely accepted, but the exact nature and role of this relationship remains quite unclear. The existence of idiosyncrasies in production and in perception sheds interesting light on the nature of the link. Indeed, a number of studies explore inter-individual variability in auditory and motor prototypes within a given language, and provide evidence for a link between both sets. In this paper, we attempt to simulate one study on coupled idiosyncrasies in the perception and production of French oral vowels, within COSMO, a Bayesian computational model of speech communication. First, we show that if the learning process in COSMO includes a communicative mechanism between a Learning Agent and a Master Agent, vowel production does display idiosyncrasies. Second, we implement within COSMO three models for speech perception that are, respectively, auditory, motor and perceptuo-motor. We show that no idiosyncrasy in perception can be obtained in the auditory model, since it is optimally tuned to the learning environment, which does not include the motor variability of the Learning Agent. On the contrary, motor and perceptuo-motor models provide perception idiosyncrasies correlated with idiosyncrasies in production. We draw conclusions about the role and importance of motor processes in speech perception, and propose a perceptuo-motor model in which auditory processing would enable optimal processing of learned sounds and motor processing would be helpful in unlearned adverse conditions.
    Keywords Medicine ; R ; Science ; Q
    Subject code 410
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Bayesian action-perception computational model

    Estelle Gilet / Julien Diard / Pierre Bessière

    PLoS ONE, Vol 6, Iss 6, p e

    interaction of production and recognition of cursive letters.

    2011  Volume 20387

    Abstract: In this paper, we study the collaboration of perception and action representations involved in cursive letter recognition and production. We propose a mathematical formulation for the whole perception-action loop, based on probabilistic modeling and ... ...

    Abstract In this paper, we study the collaboration of perception and action representations involved in cursive letter recognition and production. We propose a mathematical formulation for the whole perception-action loop, based on probabilistic modeling and bayesian inference, which we call the Bayesian Action-Perception (BAP) model. Being a model of both perception and action processes, the purpose of this model is to study the interaction of these processes. More precisely, the model includes a feedback loop from motor production, which implements an internal simulation of movement. Motor knowledge can therefore be involved during perception tasks. In this paper, we formally define the BAP model and show how it solves the following six varied cognitive tasks using bayesian inference: i) letter recognition (purely sensory), ii) writer recognition, iii) letter production (with different effectors), iv) copying of trajectories, v) copying of letters, and vi) letter recognition (with internal simulation of movements). We present computer simulations of each of these cognitive tasks, and discuss experimental predictions and theoretical developments.
    Keywords Medicine ; R ; Science ; Q
    Subject code 629
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model.

    Pierre Bessière / Marine Wasniewski / Evelyne Picard-Meyer / Alexandre Servat / Thomas Figueroa / Charlotte Foret-Lucas / Amelia Coggon / Sandrine Lesellier / Frank Boué / Nathan Cebron / Blandine Gausserès / Catherine Trumel / Gilles Foucras / Francisco J Salguero / Elodie Monchatre-Leroy / Romain Volmer

    PLoS Pathogens, Vol 17, Iss 8, p e

    2021  Volume 1009427

    Abstract: Impaired type I interferons (IFNs) production or signaling have been associated with severe COVID-19, further promoting the evaluation of recombinant type I IFNs as therapeutics against SARS-CoV-2 infection. In the Syrian hamster model, we show that ... ...

    Abstract Impaired type I interferons (IFNs) production or signaling have been associated with severe COVID-19, further promoting the evaluation of recombinant type I IFNs as therapeutics against SARS-CoV-2 infection. In the Syrian hamster model, we show that intranasal administration of IFN-α starting one day pre-infection or one day post-infection limited weight loss and decreased viral lung titers. By contrast, intranasal administration of IFN-α starting at the onset of symptoms three days post-infection had no impact on the clinical course of SARS-CoV-2 infection. Our results provide evidence that early type I IFN treatment is beneficial, while late interventions are ineffective, although not associated with signs of enhanced disease.
    Keywords Immunologic diseases. Allergy ; RC581-607 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top