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  1. Article ; Online: Assessing Performance of Machine Learning.

    Pieszko, Konrad / Slomka, Piotr J

    JAMA cardiology

    2021  Volume 6, Issue 12, Page(s) 1465

    MeSH term(s) Algorithms ; Humans ; Machine Learning
    Language English
    Publishing date 2021-10-18
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2021.3712
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  2. Article ; Online: The Comparative Method Based on Coronary Computed Tomography Angiography for Assessing the Hemodynamic Significance of Coronary Artery Stenosis.

    Małota, Zbigniew / Sadowski, Wojciech / Pieszko, Konrad / Zimoląg, Rafał / Czekała, Filip / Malinowska, Renata / Hiczkiewicz, Jarosław

    Cardiovascular engineering and technology

    2023  Volume 14, Issue 3, Page(s) 364–379

    Abstract: Purpose: An important aspect in the prevention and treatment of coronary artery disease is the functional evaluation of narrowed blood vessels. Medical image-based Computational Fluid Dynamic methods are currently increasingly being used in the clinical ...

    Abstract Purpose: An important aspect in the prevention and treatment of coronary artery disease is the functional evaluation of narrowed blood vessels. Medical image-based Computational Fluid Dynamic methods are currently increasingly being used in the clinical setting for flow studies of cardio vascular system. The aim of our study was to confirm the feasibility and functionality of a non-invasive computational method providing information about hemodynamic significance of coronary stenosis.
    Methods: A comparative method was used to simulate the flow energy losses in real (stenotic) and reconstructed models without (reference) stenosis of the coronary arteries under stress test conditions, i.e. for maximum blood flow and minimal, constant vascular resistance. In addition to the absolute pressure drop in the stenotic arteries (FFR
    Results: The greater the degree of narrowing of the vessel, the greater drop of flow energy. Each parameter introduces an additional diagnostic value. In contrast to FFR
    Conclusion: The study presented promising results of non-invasive, comparative test to support of prevention of coronary disease and functional evaluation of stenosed vessels.
    MeSH term(s) Humans ; Computed Tomography Angiography ; Constriction, Pathologic ; Retrospective Studies ; Fractional Flow Reserve, Myocardial ; Coronary Stenosis ; Coronary Artery Disease/diagnostic imaging ; Tomography, X-Ray Computed ; Coronary Angiography/methods ; Hemodynamics ; Coronary Vessels/diagnostic imaging
    Language English
    Publishing date 2023-03-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2543111-0
    ISSN 1869-4098 ; 1869-408X
    ISSN (online) 1869-4098
    ISSN 1869-408X
    DOI 10.1007/s13239-023-00658-2
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  3. Article ; Online: Artificial intelligence in cardiovascular imaging: enhancing image analysis and risk stratification.

    Lin, Andrew / Pieszko, Konrad / Park, Caroline / Ignor, Katarzyna / Williams, Michelle C / Slomka, Piotr / Dey, Damini

    BJR open

    2023  Volume 5, Issue 1, Page(s) 20220021

    Abstract: In this review, we summarize state-of-the-art artificial intelligence applications for non-invasive cardiovascular imaging modalities including CT, MRI, echocardiography, and nuclear myocardial perfusion imaging. ...

    Abstract In this review, we summarize state-of-the-art artificial intelligence applications for non-invasive cardiovascular imaging modalities including CT, MRI, echocardiography, and nuclear myocardial perfusion imaging.
    Language English
    Publishing date 2023-05-17
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2513-9878
    ISSN (online) 2513-9878
    DOI 10.1259/bjro.20220021
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  4. Article ; Online: Correction to: Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging.

    Feher, Attila / Pieszko, Konrad / Miller, Robert / Lemley, Mark / Shanbhag, Aakash / Huang, Cathleen / Miras, Leonidas / Liu, Yi-Hwa / Sinusas, Albert J / Miller, Edward J / Slomka, Piotr J

    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

    2024  Volume 30, Issue 2, Page(s) 860–863

    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1212505-2
    ISSN 1532-6551 ; 1071-3581
    ISSN (online) 1532-6551
    ISSN 1071-3581
    DOI 10.1007/s12350-022-03196-x
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  5. Article ; Online: A Randomized Study Comparing Closed-Incision Negative-Pressure Wound Therapy with Standard Care in Immediate Breast Reconstruction.

    Pieszko, Karolina / Pieszko, Konrad / Wichtowski, Mateusz / Cieśla, Sławomir / Ławnicka, Agnieszka / Jamont, Robert / Boyd, J Brian / Murawa, Dawid

    Plastic and reconstructive surgery

    2022  Volume 151, Issue 6, Page(s) 1123–1133

    Abstract: Background: Breast cancer remains the most common nonskin cancer among women. Prophylactic methods for reducing surgical-site complications after immediate breast reconstruction (IBR) are crucial to prevent acellular dermal matrices or prosthesis ... ...

    Abstract Background: Breast cancer remains the most common nonskin cancer among women. Prophylactic methods for reducing surgical-site complications after immediate breast reconstruction (IBR) are crucial to prevent acellular dermal matrices or prosthesis exposure and loss. The authors assessed the impact of closed-incision negative-pressure wound therapy (ciNPWT) versus standard dressings (ST) after IBR on surgical-site complications, superficial skin temperature (SST), skin elasticity, and subjective scar quality, to determine the potential benefit of prophylactic ciNPWT application.
    Methods: A multicenter randomized controlled study of 60 adult female patients was conducted between January of 2019 and July of 2021. All patients had oncologic indications for IBR using implants or expanders.
    Results: Application of ciNPWT correlated with a significant decrease in surgical-site complications within 1 year of surgery (total, 40%; ST, 60%; ciNPWT, 20%; P = 0.003) and resulted in more elastic scar tissue as measured with a Cutometer (average coefficient of elasticity, 0.74; ST, 0.7; ciNPWT, 0.9; P < 0.001). The SST of each scar 1 week after surgery was significantly higher in the ciNPWT group (average SST, 31.5; ST SST, 31.2; ciNPWT SST, 32.3; P = 0.006). According to the Patient and Observer Scar Assessment Scale v2.0, subjective scar outcomes in both groups were comparable.
    Conclusions: This is the first randomized controlled study that demonstrated a significant decrease in surgical-site wound complications within 1 year of surgery in IBR patients receiving ciNPWT. A high probability of postoperative radiotherapy should be a relative indication for the use of ciNPWT. .
    Clinical question/level of evidence: Therapeutic, II.
    MeSH term(s) Adult ; Humans ; Female ; Cicatrix/prevention & control ; Cicatrix/complications ; Negative-Pressure Wound Therapy/methods ; Surgical Wound/therapy ; Surgical Wound/complications ; Surgical Wound Infection/prevention & control ; Mammaplasty/adverse effects ; Mammaplasty/methods ; Breast Neoplasms/surgery ; Breast Neoplasms/complications
    Language English
    Publishing date 2022-12-26
    Publishing country United States
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000010110
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    Uk I Zs.142: Show issues Location:
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    Zs.MO 293: Show issues

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  6. Article ; Online: Predicting mortality from AI cardiac volumes mass and coronary calcium on chest computed tomography.

    Miller, Robert J H / Killekar, Aditya / Shanbhag, Aakash / Bednarski, Bryan / Michalowska, Anna M / Ruddy, Terrence D / Einstein, Andrew J / Newby, David E / Lemley, Mark / Pieszko, Konrad / Van Kriekinge, Serge D / Kavanagh, Paul B / Liang, Joanna X / Huang, Cathleen / Dey, Damini / Berman, Daniel S / Slomka, Piotr J

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 2747

    Abstract: Chest computed tomography is one of the most common diagnostic tests, with 15 million scans performed annually in the United States. Coronary calcium can be visualized on these scans, but other measures of cardiac risk such as atrial and ventricular ... ...

    Abstract Chest computed tomography is one of the most common diagnostic tests, with 15 million scans performed annually in the United States. Coronary calcium can be visualized on these scans, but other measures of cardiac risk such as atrial and ventricular volumes have classically required administration of contrast. Here we show that a fully automated pipeline, incorporating two artificial intelligence models, automatically quantifies coronary calcium, left atrial volume, left ventricular mass, and other cardiac chamber volumes in 29,687 patients from three cohorts. The model processes chamber volumes and coronary artery calcium with an end-to-end time of ~18 s, while failing to segment only 0.1% of cases. Coronary calcium, left atrial volume, and left ventricular mass index are independently associated with all-cause and cardiovascular mortality and significantly improve risk classification compared to identification of abnormalities by a radiologist. This automated approach can be integrated into clinical workflows to improve identification of abnormalities and risk stratification, allowing physicians to improve clinical decision-making.
    MeSH term(s) Humans ; Cardiac Volume ; Calcium ; Heart Ventricles ; Artificial Intelligence ; Tomography, X-Ray Computed/methods
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-46977-3
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  7. Article ; Online: Mechanical thrombectomy for acute ischemic stroke after implantation of the CoreValve Evolut R in a degenerative bioprosthetic surgical valve.

    Budzianowski, Jan / Łukawiecki, Sebastian / Burchardt, Paweł / Pieszko, Konrad / Faron, Wojciech / Hiczkiewicz, Jarosław

    Kardiologia polska

    2020  Volume 78, Issue 5, Page(s) 470–471

    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Bioprosthesis/adverse effects ; Brain Ischemia/etiology ; Heart Valve Prosthesis/adverse effects ; Humans ; Ischemic Stroke ; Prosthesis Design ; Surgical Instruments ; Thrombectomy ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2020-03-16
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.15234
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    Zs.B 598: Show issues Location:
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  8. Article: Cognitive Impairment in Cardiovascular Patients after Myocardial Infarction: Prospective Clinical Study.

    Kasprzak, Dominika / Kaczmarek-Majer, Katarzyna / Rzeźniczak, Janusz / Klamecka-Pohl, Katarzyna / Ganowicz-Kaatz, Teresa / Słomczyński, Marek / Budzianowski, Jan / Pieszko, Konrad / Hiczkiewicz, Jarosław / Tykarski, Andrzej / Burchardt, Paweł

    Journal of clinical medicine

    2023  Volume 12, Issue 15

    Abstract: 1) Background: Assessment of cognitive function is not routine in cardiac patients, and knowledge on the subject remains limited. The aim of this study was to assess post-myocardial infarction (MI) cognitive functioning in order to determine the ... ...

    Abstract (1) Background: Assessment of cognitive function is not routine in cardiac patients, and knowledge on the subject remains limited. The aim of this study was to assess post-myocardial infarction (MI) cognitive functioning in order to determine the frequency of cognitive impairment (CI) and to identify factors that may influence it. (2) Methods: A prospective study included 468 patients hospitalized for MI. Participants were assessed twice: during the first hospitalization and 6 months later. The Mini-Mental State Examination was used to assess the occurrence of CI. (3) Results: Cognitive dysfunction based on the MMSE was found in 37% (N-174) of patients during the first hospitalization. After 6 months, the prevalence of deficits decreased significantly to 25% (N-91) (
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12154954
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  9. Article ; Online: Cognitive impairment in patients after myocardial infarction.

    Kasprzak, Dominika / Ganowicz-Kaatz, Teresa / Rzeźniczak, Janusz / Słomczyński, Marek / Kaczmarek-Majer, Katarzyna / Budzianowski, Jan / Pieszko, Konrad / Hiczkiewicz, Jarosław / Tykarski, Andrzej / Burchardt, Paweł

    Kardiologia polska

    2023  Volume 81, Issue 5, Page(s) 505–507

    MeSH term(s) Humans ; Cognitive Dysfunction/etiology ; Myocardial Infarction/complications
    Language English
    Publishing date 2023-03-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2023.0056
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    Zs.B 598: Show issues Location:
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  10. Article ; Online: Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging.

    Feher, Attila / Pieszko, Konrad / Shanbhag, Aakash / Lemley, Mark / Miller, Robert Jh / Huang, Cathleen / Miras, Leonidas / Liu, Yi-Hwa / Gerber, Jamie / Sinusas, Albert J / Miller, Edward J / Slomka, Piotr J

    The international journal of cardiovascular imaging

    2023  Volume 40, Issue 1, Page(s) 185–193

    Abstract: We investigated the prognostic utility of visually estimated coronary artery calcification (VECAC) from low dose computed tomography attenuation correction (CTAC) scans obtained during SPECT/CT myocardial perfusion imaging (MPI), and assessed how it ... ...

    Abstract We investigated the prognostic utility of visually estimated coronary artery calcification (VECAC) from low dose computed tomography attenuation correction (CTAC) scans obtained during SPECT/CT myocardial perfusion imaging (MPI), and assessed how it compares to coronary artery calcifications (CAC) quantified by calcium score on CTACs (QCAC). From the REFINE SPECT Registry 4,236 patients without prior coronary stenting with SPECT/CT performed at a single center were included (age: 64 ± 12 years, 47% female). VECAC in each coronary artery (left main, left anterior descending, circumflex, and right) were scored separately as 0 (absent), 1 (mild), 2 (moderate), or 3 (severe), yielding a possible score of 0-12 for each patient (overall VECAC grade zero:0, mild:1-2, moderate: 3-5, severe: >5). CAC scoring of CTACs was performed at the REFINE SPECT core lab with dedicated software. VECAC was correlated with categorized QCAC (zero: 0, mild: 1-99, moderate: 100-399, severe: ≥400). A high degree of correlation was observed between VECAC and QCAC, with 73% of VECACs in the same category as QCAC and 98% within one category. There was substantial agreement between VECAC and QCAC (weighted kappa: 0.78 with 95% confidence interval: 0.76-0.79, p < 0.001). During a median follow-up of 25 months, 372 patients (9%) experienced major adverse cardiovascular events (MACE). In survival analysis, both VECAC and QCAC were associated with MACE. The area under the receiver operating characteristic curve for 2-year-MACE was similar for VECAC when compared to QCAC (0.694 versus 0.691, p = 0.70). In conclusion, visual assessment of CAC on low-dose CTAC scans provides good estimation of QCAC in patients undergoing SPECT/CT MPI. Visually assessed CAC has similar prognostic value for MACE in comparison to QCAC.
    MeSH term(s) Humans ; Female ; Middle Aged ; Aged ; Male ; Myocardial Perfusion Imaging/methods ; Prognosis ; Predictive Value of Tests ; Tomography, Emission-Computed, Single-Photon/methods ; Coronary Artery Disease/diagnostic imaging ; Tomography, X-Ray Computed/methods ; Calcinosis
    Language English
    Publishing date 2023-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-023-02980-1
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