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  1. Article ; Online: The pandemic characteristics of 2019-nCoV

    Roberto Ronchetti / Pietro Massimiliano Bianco

    Italian Journal of Pediatrics, Vol 46, Iss 1, Pp 1-

    case-control study for severity and geographic locations for 2019-nCoV epidemics worldwide

    2020  Volume 4

    Abstract: Abstract Using available official data we found 248 epidemics curves caused worldwide by the 2019-nCoV in the period December 2019–March 31st 2020. The analysis of this material allowed two main observations: 1) it is possible to describe the main ... ...

    Abstract Abstract Using available official data we found 248 epidemics curves caused worldwide by the 2019-nCoV in the period December 2019–March 31st 2020. The analysis of this material allowed two main observations: 1) it is possible to describe the main geographical pathway of the diffusion of the virus in different directions. This strongly suggests a unique point of origin of the pandemics in Wuhan, China, from where it spread in many different directions. 2) of the 74 epidemics which were characterized by at least 1000 cases, 65 (90%) were located in the geographic region of the world delimitated by 52–30 degrees latitude North. Viceversa 110 (60%) of the 176 epidemics with less than 1000 cases were located outside the cited geographical world region. These results suggest considerations on the pandemic characteristics of 2019-nCoV.
    Keywords Coronavirus ; 2019-nCoV ; COVID-19 outbreak ; Epidemics ; Pathway of spread ; Severity of epidemics ; Pediatrics ; RJ1-570 ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Air Pollution and COVID-19

    Luigi Montano / Francesco Donato / Pietro Massimiliano Bianco / Gennaro Lettieri / Antonino Guglielmino / Oriana Motta / Ian Marc Bonapace / Marina Piscopo

    International Journal of Environmental Research and Public Health, Vol 18, Iss 6846, p

    A Possible Dangerous Synergy for Male Fertility

    2021  Volume 6846

    Abstract: Several studies indicate that semen quality has strongly declined in the last decades worldwide. Air pollution represents a significant co-factor with the COVID-19 impact and has negative effects on the male reproductive system, through pro-oxidant, ... ...

    Abstract Several studies indicate that semen quality has strongly declined in the last decades worldwide. Air pollution represents a significant co-factor with the COVID-19 impact and has negative effects on the male reproductive system, through pro-oxidant, inflammatory and immune-dysregulating mechanisms. It has recently been reported that chronic exposure to PM2.5 causes overexpression of the alveolar ACE2 receptor, the entry route of SARS-CoV-2 into the organism shared by the lungs and testis where expression is highest in the body. In the testis, the ACE2/Ang-(1–7)/MasR pathway plays an important role in the regulation of spermatogenesis and an indirect mechanism of testicular damage could be due to the blockade of the ACE2 receptor by SARS-CoV-2. This prevents the conversion of specific angiotensins, and their excess causes inflammation with the overproduction of cytokines. PM2.5-induced overexpression of the alveolar ACE2 receptor, in turn, could increase local viral load in patients exposed to pollutants, producing ACE2 receptor depletion and compromising host defenses. By presenting an overall view of epidemiological data and molecular mechanisms, this manuscript aims to interpret the possible synergistic effects of both air pollution and COVID-19 on male reproductive function, warning that the spread of SARS-CoV-2 in the fertile years may represent a significant threat to global reproductive health. All of this should be of great concern, especially for men of the age of maximum reproductive capacity, and an important topic of debate for policy makers. Altered environmental conditions, together with the direct and indirect short- and long-term effects of viral infection could cause a worsening of semen quality with important consequences for male fertility, especially in those areas with higher environmental impact.
    Keywords COVID-19 ; SARS-CoV-2 ; male fertility ; semen quality ; air pollution ; ACE2 ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Estimation of the Allergenic Potential of Urban Trees and Urban Parks

    Paloma Cariñanos / Filipa Grilo / Pedro Pinho / Manuel Casares-Porcel / Cristina Branquinho / Nezha Acil / Maria Beatrice Andreucci / Andreia Anjos / Pietro Massimiliano Bianco / Silvia Brini / Pedro Calaza-Martínez / Enrico Calvo / Elisa Carrari / José Castro / Anna Chiesura / Otilia Correia / Artur Gonçalves / Paula Gonçalves / Teresa Mexia /
    Marzia Mirabile / Elena Paoletti / Margarida Santos-Reis / Paolo Semenzato / Ursa Vilhar

    International Journal of Environmental Research and Public Health, Vol 16, Iss 8, p

    Towards the Healthy Design of Urban Green Spaces of the Future

    2019  Volume 1357

    Abstract: The impact of allergens emitted by urban green spaces on health is one of the main disservices of ecosystems. The objective of this work is to establish the potential allergenic value of some tree species in urban environments, so that the allergenicity ... ...

    Abstract The impact of allergens emitted by urban green spaces on health is one of the main disservices of ecosystems. The objective of this work is to establish the potential allergenic value of some tree species in urban environments, so that the allergenicity of green spaces can be estimated through application of the Index of Urban Green Zones Allergenicity (I UGZA ). Multiple types of green spaces in Mediterranean cities were selected for the estimation of I UGZ . The results show that some of the ornamental species native to the Mediterranean are among the main causative agents of allergy in the population; in particular, Oleaceae, Cupressaceae, Fagaceae, and Platanus hispanica . Variables of the strongest impact on I UGZA were the bioclimatic characteristics of the territory and design aspects, such as the density of trees and the number of species. We concluded that the methodology to assess the allergenicity associated with urban trees and urban areas presented in this work opens new perspectives in the design and planning of urban green spaces, pointing out the need to consider the potential allergenicity of a species when selecting plant material to be used in cities. Only then can urban green areas be inclusive spaces, in terms of public health.
    Keywords index of urban green zone allergenicity ; cost of greening ; impact on health ; ecosystem disservices ; allergenic trees ; value of potential allergenicity (VPA) ; Medicine ; R
    Subject code 710
    Language English
    Publishing date 2019-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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