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  1. Article ; Online: Systematic basic and advanced resuscitation training in medical students and fellows: a proposal from the Working Group on Cardiovascular Urgences and Emergencies of the Italian Society of Cardiology.

    Saba, Pier Sergio / Canonico, Mario Enrico / Gambaro, Alessia / Gazale, Giovanni / Piga, Stefania / Santomauro, Maurizio / Roscio, Giancarlo

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue Suppl 2, Page(s) e128–e133

    Abstract: Sudden cardiac arrest is a leading cause of death in Europe. High-quality cardiopulmonary resuscitation (CPR) and guidelines compliance of rescuers have been associated with better outcomes after cardiac arrest. However, wide variability in attempting ... ...

    Abstract Sudden cardiac arrest is a leading cause of death in Europe. High-quality cardiopulmonary resuscitation (CPR) and guidelines compliance of rescuers have been associated with better outcomes after cardiac arrest. However, wide variability in attempting bystander CPR manoeuvres has been reported. Educational programmes for teaching CPR to medical students and fellows are highly advisable in this context. However, there is no homogeneity regarding the CPR education offered by academic institutions. We surveyed 208 Italian medical students and 162 fellows in cardiology regarding the educational offer and needs in CPR. Among the 11 medical schools surveyed, 8 (73%) offer basic (BLS) courses but only 3 (38%) with formal certification of 'BLS provider', while none offers advanced (ACLS/ALS) courses. Among the 30 specialization schools in cardiology surveyed, 10 (33%) offer a BLS course (6 with formal certification of 'BLS provider'), and 8 (27%) offer an ACLS/ALS course (5 with formal certification). Only a minority of students and fellows perceive themselves as highly proficient either in BLS or ACLS/ALS, although most of the fellows were involved at least once in rescuing a cardiac arrest. The present position paper analyses and suggests the strategies that should be adopted by Italian medical and specialization schools to spread the CPR culture and increase the long-standing retention of CPR-related technical and nontechnical skills.
    MeSH term(s) Humans ; Cardiology/education ; Cardiopulmonary Resuscitation/education ; Emergencies ; Heart Arrest/therapy ; Italy ; Students, Medical
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5210: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 559: Show issues

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  2. Article ; Online: Electrocardiography in Children Hospitalized for COVID-19 and Not Suffering from Multisystem Inflammatory Syndrome in Children (MIS-C): An Observational Study.

    Locci, Cristian / Bassareo, Pier Paolo / Fanelli, Chiara / Maida, Ivana / Saderi, Laura / Puci, Mariangela V / Sotgiu, Giovanni / Culeddu, Maria Chiara / Piga, Stefania / Oppo, Antonella / Antonucci, Roberto

    Journal of cardiovascular development and disease

    2024  Volume 11, Issue 3

    Abstract: The risk of cardiac involvement with electrophysiological abnormalities during COVID-19 infection has been reported in adults but remains poorly studied in children. Our aim was to determine the frequency of cardiac involvement and the necessity of ... ...

    Abstract The risk of cardiac involvement with electrophysiological abnormalities during COVID-19 infection has been reported in adults but remains poorly studied in children. Our aim was to determine the frequency of cardiac involvement and the necessity of routine cardiac evaluation in children hospitalized for COVID-19. This observational study included 127 children, with a median (IQR) age of 2 (0.83-6.0) years, who were hospitalized for COVID-19 between 1 January 2021 and 31 August 2022, 62 (48.8%) of whom were males. Each patient underwent an ECG on admission and discharge as well as a laboratory assessment. A comparison between patients with COVID-19 and healthy controls showed significantly higher HR (
    Language English
    Publishing date 2024-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd11030085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Genetic Screening of Anderson-Fabry Disease in Probands Referred From Multispecialty Clinics.

    Favalli, Valentina / Disabella, Eliana / Molinaro, Mariadelfina / Tagliani, Marilena / Scarabotto, Anna / Serio, Alessandra / Grasso, Maurizia / Narula, Nupoor / Giorgianni, Carmela / Caspani, Clelia / Concardi, Monica / Agozzino, Manuela / Giordano, Calogero / Smirnova, Alexandra / Kodama, Takahide / Giuliani, Lorenzo / Antoniazzi, Elena / Borroni, Riccardo G / Vassallo, Camilla /
    Mangione, Filippo / Scelsi, Laura / Ghio, Stefano / Pellegrini, Carlo / Zedde, Marialuisa / Fancellu, Laura / Sechi, GianPietro / Ganau, Antonello / Piga, Stefania / Colucci, Annarita / Concolino, Daniela / Di Mascio, Maria Teresa / Toni, Danilo / Diomedi, Marina / Rapezzi, Claudio / Biagini, Elena / Marini, Massimiliano / Rasura, Maurizia / Melis, Maurizio / Nucera, Antonia / Guidetti, Donata / Mancuso, Michelangelo / Scoditti, Umberto / Cassini, Pamela / Narula, Jagat / Tavazzi, Luigi / Arbustini, Eloisa

    Journal of the American College of Cardiology

    2016  Volume 68, Issue 10, Page(s) 1037–1050

    Abstract: Background: Anderson-Fabry disease (AFD) is a rare X-linked lysosomal storage disease, caused by defects of the alpha-galactosidase A (GLA) gene. AFD can affect the heart, brain, kidney, eye, skin, peripheral nerves, and gastrointestinal tract. ... ...

    Abstract Background: Anderson-Fabry disease (AFD) is a rare X-linked lysosomal storage disease, caused by defects of the alpha-galactosidase A (GLA) gene. AFD can affect the heart, brain, kidney, eye, skin, peripheral nerves, and gastrointestinal tract. Cardiology (hypertrophic cardiomyopathy), neurology (cryptogenic stroke), and nephrology (end-stage renal failure) screening studies suggest the prevalence of GLA variants is 0.62%, with diagnosis confirmation in 0.12%.
    Objectives: This study sought to expand screening from these settings to include ophthalmology, dermatology, gastroenterology, internal medicine, pediatrics, and medical genetics to increase diagnostic yield and comprehensively evaluate organ involvement in AFD patients.
    Methods: In a 10-year prospective multidisciplinary, multicenter study, we expanded clinical, genetic, and biochemical screening to consecutive patients enrolled from all aforementioned clinical settings. We tested the GLA gene and α-galactosidase A activity in plasma and leukocytes. Inclusion criteria comprised phenotypical traits and absence of male-to-male transmission. Screening was extended to relatives of probands harboring GLA mutations.
    Results: Of 2,034 probands fulfilling inclusion criteria, 37 (1.8%) were carriers of GLA mutations. Cascade family screening identified 60 affected relatives; clinical data were available for 4 affected obligate carriers. Activity of α-galactosidase A in plasma and leukocytes was diagnostic in male subjects, but not in female subjects. Of the 101 family members harboring mutations, 86 were affected, 10 were young healthy carriers, and 5 refused clinical evaluation. In the 86 patients, involved organs or organ systems included the heart (69%), peripheral nerves (46%), kidney (45%), eye (37%), brain (34%), skin (32%), gastrointestinal tract (31%), and auditory system (19%). Globotriaosylceramide accumulated in organ-specific and non-organ-specific cells in atypical and classic variants, respectively.
    Conclusions: Screening probands with clinically suspected AFD significantly increased diagnostic yield. The heart was the organ most commonly involved, independent of the clinical setting in which the patient was first evaluated.
    MeSH term(s) Adolescent ; Adult ; Child ; Fabry Disease/diagnosis ; Fabry Disease/genetics ; Female ; Genetic Testing ; Hospitals ; Humans ; Male ; Medicine ; Middle Aged ; Mutation ; Prospective Studies ; alpha-Galactosidase/genetics
    Chemical Substances alpha-Galactosidase (EC 3.2.1.22)
    Language English
    Publishing date 2016-08-31
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2016.05.090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1846: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 196: Show issues

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