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  1. AU="Pike, J Wesley"
  2. AU="Heijdra Suasnabar, Jan M"
  3. AU="Galanaud, Damien"
  4. AU="Edmison, Anna"
  5. AU="Hall, Charles B"

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  1. Article ; Online: Genomic mechanisms controlling renal vitamin D metabolism.

    Meyer, Mark B / Pike, J Wesley

    The Journal of steroid biochemistry and molecular biology

    2023  Volume 228, Page(s) 106252

    Abstract: Vitamin D metabolism centers on regulation in the kidney of CYP27B1 induction by PTH, suppression by FGF23 and 1,25(OH) ...

    Abstract Vitamin D metabolism centers on regulation in the kidney of CYP27B1 induction by PTH, suppression by FGF23 and 1,25(OH)
    MeSH term(s) Mice ; Animals ; Calcitriol/pharmacology ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolism ; Vitamin D3 24-Hydroxylase/genetics ; Vitamin D3 24-Hydroxylase/metabolism ; Kidney/metabolism ; Genomics ; Receptors, Calcitriol/metabolism ; Vitamin D/metabolism
    Chemical Substances Calcitriol (FXC9231JVH) ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase (EC 1.14.15.18) ; Vitamin D3 24-Hydroxylase (EC 1.14.15.16) ; Receptors, Calcitriol ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2023-01-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2023.106252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 708: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Molecular insights into mineralotropic hormone inter-regulation.

    Pike, J Wesley / Lee, Seong Min / Meyer, Mark B

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1213361

    Abstract: The regulation of mineral homeostasis involves the three mineralotropic hormones PTH, FGF23 and 1,25-dihydroxyvitamin ... ...

    Abstract The regulation of mineral homeostasis involves the three mineralotropic hormones PTH, FGF23 and 1,25-dihydroxyvitamin D
    MeSH term(s) Humans ; Calcitriol/metabolism ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics ; Parathyroid Hormone/metabolism ; Kidney/metabolism ; Calcium/metabolism
    Chemical Substances Calcitriol (FXC9231JVH) ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase (EC 1.14.15.18) ; Parathyroid Hormone ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-06-27
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1213361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Genome-wide analyses of gene expression profile identify key genes and pathways involved in skeletal response to phosphate and 1,25-dihydroxyvitamin D

    Lee, Seong Min / Meyer, Mark B / Benkusky, Nancy A / Pike, J Wesley

    The Journal of steroid biochemistry and molecular biology

    2023  Volume 232, Page(s) 106335

    Abstract: Phosphate (P) is an essential element involved in various biological actions, such as bone integrity, energy production, cell signaling and molecular component. P homeostasis is modulated by 4 main tissues; intestine, kidney, bone, and parathyroid gland, ...

    Abstract Phosphate (P) is an essential element involved in various biological actions, such as bone integrity, energy production, cell signaling and molecular component. P homeostasis is modulated by 4 main tissues; intestine, kidney, bone, and parathyroid gland, where 1,25-dihydroxyvitamin D
    MeSH term(s) Mice ; Animals ; Calcitriol/pharmacology ; Calcitriol/metabolism ; Phosphates ; Transcriptome ; Genome-Wide Association Study ; Vitamin D/pharmacology ; Vitamin D/metabolism ; 24,25-Dihydroxyvitamin D 3 ; Calcium/metabolism
    Chemical Substances 1,25-dihydroxyvitamin D (66772-14-3) ; Calcitriol (FXC9231JVH) ; Phosphates ; Vitamin D (1406-16-2) ; 24,25-Dihydroxyvitamin D 3 (40013-87-4) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-05-27
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2023.106335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 708: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: The unsettled science of nonrenal calcitriol production and its clinical relevance.

    Pike, J Wesley / Meyer, Mark B

    The Journal of clinical investigation

    2020  Volume 130, Issue 9, Page(s) 4519–4521

    MeSH term(s) 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolism ; Animals ; Calcitriol/metabolism ; Cholestanetriol 26-Monooxygenase/metabolism ; Cytochrome P450 Family 2/metabolism ; Humans ; Kidney/metabolism ; Liver/metabolism
    Chemical Substances Cytochrome P450 Family 2 (EC 1.14.14.1) ; CYP2R1 protein, human (EC 1.14.14.24) ; Cholestanetriol 26-Monooxygenase (EC 1.14.15.15) ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase (EC 1.14.15.18) ; CYP27B1 protein, human (EC 1.14.15.18) ; Calcitriol (FXC9231JVH)
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI141334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Closing in on Vitamin D Action in Skeletal Muscle: Early Activity in Muscle Stem Cells?

    Pike, J Wesley

    Endocrinology

    2016  Volume 157, Issue 1, Page(s) 48–51

    MeSH term(s) Calcitriol/metabolism ; Female ; Gene Expression Regulation, Developmental ; Humans ; Male ; Muscle Development ; Muscle Fibers, Skeletal/metabolism ; Myoblasts, Skeletal/metabolism ; Receptors, Calcitriol/agonists ; Signal Transduction
    Chemical Substances Receptors, Calcitriol ; Calcitriol (FXC9231JVH)
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Comment ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 427856-2
    ISSN 1945-7170 ; 0013-7227
    ISSN (online) 1945-7170
    ISSN 0013-7227
    DOI 10.1210/en.2015-2009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mechanistic homeostasis of vitamin D metabolism in the kidney through reciprocal modulation of Cyp27b1 and Cyp24a1 expression.

    Meyer, Mark B / Pike, J Wesley

    The Journal of steroid biochemistry and molecular biology

    2019  Volume 196, Page(s) 105500

    Abstract: Cyp27b1 and Cyp24a1 are reciprocally regulated in the kidney by the key hormones PTH, FGF23, and 1,25(OH) ...

    Abstract Cyp27b1 and Cyp24a1 are reciprocally regulated in the kidney by the key hormones PTH, FGF23, and 1,25(OH)
    MeSH term(s) 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolism ; Animals ; Calcitriol/pharmacology ; Calcium/metabolism ; Calcium/pharmacology ; Fibroblast Growth Factors/pharmacology ; Gene Expression Regulation, Enzymologic/drug effects ; Homeostasis/drug effects ; Homeostasis/physiology ; Humans ; Kidney/drug effects ; Kidney/metabolism ; Parathyroid Hormone/pharmacology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Vitamin D/metabolism ; Vitamin D3 24-Hydroxylase/genetics ; Vitamin D3 24-Hydroxylase/metabolism
    Chemical Substances Parathyroid Hormone ; Vitamin D (1406-16-2) ; Fibroblast Growth Factors (62031-54-3) ; fibroblast growth factor 23 (7Q7P4S7RRE) ; Vitamin D3 24-Hydroxylase (EC 1.14.15.16) ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase (EC 1.14.15.18) ; Calcitriol (FXC9231JVH) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-10-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2019.105500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 708: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Expression of the vitamin D receptor in skeletal muscle: are we there yet?

    Pike, J Wesley

    Endocrinology

    2014  Volume 155, Issue 9, Page(s) 3214–3218

    MeSH term(s) Animals ; Humans ; Male ; Muscle, Skeletal/metabolism ; Myofibrils/metabolism ; Receptors, Calcitriol/metabolism ; Vitamin D/analogs & derivatives ; Vitamin D/metabolism ; Vitamin D Deficiency/metabolism
    Chemical Substances Receptors, Calcitriol ; Vitamin D (1406-16-2) ; 25-hydroxyvitamin D (A288AR3C9H)
    Language English
    Publishing date 2014-08-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 427856-2
    ISSN 1945-7170 ; 0013-7227
    ISSN (online) 1945-7170
    ISSN 0013-7227
    DOI 10.1210/en.2014-1624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  8. Article: The unsettled science of nonrenal calcitriol production and its clinical relevance

    Pike, J. Wesley / Meyer, Mark B.

    Journal of Clinical Investigation

    Abstract: The primary function of vitamin D in higher vertebrates is to regulate mineral homeostasis through direct actions on intestinal calcium and phosphate absorption, bone mineral resorption, and renal mineral reabsorption Vitamin D itself is inactive and ... ...

    Abstract The primary function of vitamin D in higher vertebrates is to regulate mineral homeostasis through direct actions on intestinal calcium and phosphate absorption, bone mineral resorption, and renal mineral reabsorption Vitamin D itself is inactive and must undergo sequential modification via two specific chemical reactions, first in the liver to 25(OH)D3 by the enzyme CYP2R1, and then in the kidney to 1,25-dihydroxyvitamin D3 by the tightly regulated enzyme CYP27B1 Calcitriol, whose level is also modulated via renal CYP24A1-mediated degradation, is then secreted into the blood as an active endocrine hormone and delivered to distant target tissues Here, Pike and Meyer discuss the importance of adequate blood levels of vitamin D and the models for characterizing features of NRTC calcitriol production
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #829994
    Database COVID19

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  9. Book: Vitamin D

    Feldman, David / Pike, J. Wesley / Bouillon, R

    2018  

    Author's details editor-in-chief, David Feldman, senior associate editor, J. Wesley Pike, associate editors, Roger Bouillon [and 3 others]
    Keywords Vitamin D. ; vitamin D ; vitamin D deficiency
    Language English
    Dates of publication 2018-2018
    Size 2 volumes :, illustrations (some color) ;, 29 cm
    Edition Fourth edition.
    Document type Book
    Note Revised edition of: Vitamin D / editor-in-chief, David Feldman ; associate editors, J. Wesley Pike, John S. Adams. 3rd ed. 2011.
    ISBN 9780128099650 ; 0128099658 ; 9780128099636 ; 0128099631 ; 9780128099667 ; 0128099666
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Biology and Mechanisms of Action of the Vitamin D Hormone.

    Pike, J Wesley / Christakos, Sylvia

    Endocrinology and metabolism clinics of North America

    2017  Volume 46, Issue 4, Page(s) 815–843

    Abstract: The central role of hormonal 1,25-dihydroxyvitamin ... ...

    Abstract The central role of hormonal 1,25-dihydroxyvitamin D
    MeSH term(s) Animals ; Bone and Bones/metabolism ; Calcitriol/metabolism ; Calcium/metabolism ; Homeostasis/physiology ; Humans ; Receptors, Calcitriol/physiology ; Signal Transduction/physiology ; Vitamin D/physiology
    Chemical Substances Receptors, Calcitriol ; Vitamin D (1406-16-2) ; Calcitriol (FXC9231JVH) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2017.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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