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  1. Article ; Online: Understanding lymphoma molecular complexity.

    Pileri, Stefano A

    Blood

    2017  Volume 130, Issue 16, Page(s) 1780–1781

    MeSH term(s) Humans ; Lymphoma, Large B-Cell, Diffuse
    Language English
    Publishing date 2017-10-17
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2017-08-802223
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  2. Article ; Online: TOSCA: an automated Tumor Only Somatic CAlling workflow for somatic mutation detection without matched normal samples.

    Del Corvo, Marcello / Mazzara, Saveria / Pileri, Stefano A

    Bioinformatics advances

    2022  Volume 2, Issue 1, Page(s) vbac070

    Abstract: Motivation: Accurate classification of somatic variants in a tumor sample is often accomplished by utilizing a paired normal tissue sample from the same patient to enable the separation of private germline mutations from somatic variants. However, a ... ...

    Abstract Motivation: Accurate classification of somatic variants in a tumor sample is often accomplished by utilizing a paired normal tissue sample from the same patient to enable the separation of private germline mutations from somatic variants. However, a paired normal sample is not always available, making a reliable somatic variant calling more challenging.
    Results: To address these limitations, we developed TOSCA, the first automated tumor-only somatic calling workflow in whole-exome sequencing and targeted panel sequencing data which performs an end-to-end analysis from raw read files, via quality checks, alignment and variant calling to functional annotation, databases filtering, tumor purity and ploidy estimation and variant classification. Application of our workflow to tumor-only data provides estimates of somatic and germline variants that are consistent with results from paired analyses.
    Availability and implementation: TOSCA is a Snakemake-based workflow and freely available at https://github.com/mdelcorvo/TOSCA.
    Supplementary information: Supplementary data are available at
    Language English
    Publishing date 2022-09-26
    Publishing country England
    Document type Journal Article
    ISSN 2635-0041
    ISSN (online) 2635-0041
    DOI 10.1093/bioadv/vbac070
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  3. Article ; Online: Histiocytic and dendritic cell neoplasms.

    Pileri, Stefano A / Melle, Federica / Motta, Giovanna / Tabanelli, Valentina

    Pathologie (Heidelberg, Germany)

    2022  

    Abstract: Background: Histiocytic and dendritic cell neoplasms (HDCNs) represent very rare tumors, which have been the subject of debate during the last few years.: Objectives: We aimed to provide a comprehensive review of the subject.: Materials and methods! ...

    Title translation Histiozytische und dendritische Zelltumoren.
    Abstract Background: Histiocytic and dendritic cell neoplasms (HDCNs) represent very rare tumors, which have been the subject of debate during the last few years.
    Objectives: We aimed to provide a comprehensive review of the subject.
    Materials and methods: The experience gained by the authors in large international studies and as a national reference center has been summarized to highlight the characteristics of each entity.
    Results: The clinical, morphologic, phenotypic, and molecular data of the different entities included under the heading of HDCNs are extensively discussed.
    Conclusion: Currently, HDCNs are classified in the group of orphan diseases for which a standardized therapy is lacking. An international registry would facilitate expansion and dissemination of knowledge of these diseases and improve their treatment.
    Language English
    Publishing date 2022-09-29
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-022-01116-x
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  4. Article ; Online: Follicular helper T-cell-related lymphomas.

    Pileri, Stefano A

    Blood

    2015  Volume 126, Issue 15, Page(s) 1733–1734

    Abstract: In this issue of Blood, Wang et al describe the occurrence and pathogenetic relevance of IDH2R172 mutations in angioimmunoblastic T-cell lymphoma (AITL). ...

    Abstract In this issue of Blood, Wang et al describe the occurrence and pathogenetic relevance of IDH2R172 mutations in angioimmunoblastic T-cell lymphoma (AITL).
    MeSH term(s) Epigenesis, Genetic/genetics ; Humans ; Immunoblastic Lymphadenopathy/classification ; Isocitrate Dehydrogenase/genetics ; Lymphoma, T-Cell/classification ; Mutation/genetics
    Chemical Substances Isocitrate Dehydrogenase (EC 1.1.1.41)
    Language English
    Publishing date 2015-10-07
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2015-08-665075
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  5. Article ; Online: Plasmablastic lymphoma: one or more tumors?

    Pileri, Stefano A / Mazzara, Saveria / Derenzini, Enrico

    Haematologica

    2021  Volume 106, Issue 10, Page(s) 2542–2543

    MeSH term(s) Humans ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Plasma Cells ; Plasmablastic Lymphoma/diagnosis ; Plasmablastic Lymphoma/epidemiology ; Plasmablastic Lymphoma/therapy
    Language English
    Publishing date 2021-10-01
    Publishing country Italy
    Document type Editorial ; Comment
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2021.278841
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  6. Article ; Online: Case 38-2013: A man with fever and lymphadenopathy.

    Pileri, Stefano A

    The New England journal of medicine

    2014  Volume 370, Issue 11, Page(s) 1077

    MeSH term(s) Histiocytic Necrotizing Lymphadenitis/pathology ; Humans ; Lymph Nodes/pathology ; Male
    Language English
    Publishing date 2014-03-13
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1400186#SA3
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  7. Article ; Online: "Old" is "new" in diagnostic pathology.

    Pileri, Stefano A

    Human pathology

    2013  Volume 44, Issue 9, Page(s) 1705–1706

    MeSH term(s) Female ; Hodgkin Disease/pathology ; Humans ; Lymph Nodes/pathology ; Lymphatic Diseases/pathology ; Male ; T-Lymphocytes, Helper-Inducer/pathology
    Language English
    Publishing date 2013-09
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/j.humpath.2013.03.011
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    Zs.A 722: Show issues Location:
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  8. Article ; Online: A Rare Case of BIA-ALCL Mass Associated with Mastectomy Skin Flap Erythema After Immunization with COVID-19.

    Garusi, Cristina / De Antoni, Eleonora / Fiori, Stefano / Vanazzi, Anna / Pileri, Stefano A

    Aesthetic plastic surgery

    2022  Volume 47, Issue 1, Page(s) 116–121

    Abstract: Background: The immune response to breast implants after COVID-19 disease or COVID-19 vaccine administration includes acute inflammatory manifestations, capsular contracture and seroma. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) ...

    Abstract Background: The immune response to breast implants after COVID-19 disease or COVID-19 vaccine administration includes acute inflammatory manifestations, capsular contracture and seroma. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a very rare tumor in which numerous up-regulated pro-inflammatory immunological pathways activate a T cell lymphoproliferative disorder.
    Methods: The first reported case of a BIA-ALCL hidden mass clinically manifesting with inflammatory signs after SARS-CoV-2 infection and vaccinations is here described.
    Results: Complete capsulectomy and adjuvant chemotherapy were performed and immediately after the surgical procedure local inflammatory signs disappeared; no evidence of disease was present 1 year later.
    Conclusions: Immunological stimulation by COVID-19 disease and vaccines may highlight some rare clinical manifestations of BIA-ALCL; persistent inflammatory symptomatology over breast implants should be investigated using second-level imaging.
    Level of evidence v: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    MeSH term(s) Humans ; Female ; Breast Implants ; Lymphoma, Large-Cell, Anaplastic/pathology ; COVID-19 Vaccines ; Breast Neoplasms/surgery ; Mastectomy ; COVID-19 ; SARS-CoV-2 ; Breast Implantation/methods ; Immunization ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-11-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-022-03174-1
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  9. Article ; Online: A five-gene signature may associate with central nervous system dissemination in adult acute lymphoblastic leukemia.

    Sapienza, Maria Rosaria / Chiaretti, Sabina / Cardinali, Deborah / Mazzara, Saveria / Chiarle, Roberto / Foà, Robin / Pileri, Stefano A

    Hematological oncology

    2023  Volume 41, Issue 4, Page(s) 789–791

    MeSH term(s) Humans ; Adult ; Central Nervous System ; Central Nervous System Neoplasms/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics
    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Letter
    ZDB-ID 604884-5
    ISSN 1099-1069 ; 0278-0232
    ISSN (online) 1099-1069
    ISSN 0278-0232
    DOI 10.1002/hon.3136
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  10. Article ; Online: Diffuse large B-cell lymphoma: the stuff of cell-of-origin and microenvironment.

    Pileri, Stefano A / Vegliante, Maria Carmela / Ciavarella, Sabino

    Oncotarget

    2019  Volume 10, Issue 40, Page(s) 3991–3993

    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.27013
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