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  1. AU="Pillas, Diana J"
  2. AU="Thomson, Jason J"
  3. AU="Mitra, Kalyan"
  4. AU="Sanjay Desai"
  5. AU=Cox David J AU=Cox David J
  6. AU="Grebenok, Robert J."
  7. AU="Blackburne, Brittney"
  8. AU="Bortoleti, Bruna Taciane da Silva"
  9. AU="Ehrbar, Martin"
  10. AU="Lepre, Davide"
  11. AU="Olszewska, Zuzanna"
  12. AU="Vojta, Leslie"
  13. AU=Wickstrom Eric AU=Wickstrom Eric
  14. AU="Gangavarapu, Sridevi"
  15. AU="Hussein, Hazem Abdelwaheb"
  16. AU=Cai Yixin AU=Cai Yixin
  17. AU="Hüls, Anke"
  18. AU="Poondru, Srinivasu"
  19. AU="Coca, Daniel"
  20. AU="Lebeau, Paul"
  21. AU="Dehghani, Sedigheh"
  22. AU="Ishibashi, Kenji"
  23. AU="Xu, Yanhua"
  24. AU="Matera, Katarzyna"
  25. AU="Ait-Ouarab, Slimane"
  26. AU="Nicola, Coppede"
  27. AU="Dewitt, John M"
  28. AU="Sorin M. Dudea"
  29. AU="Tanusha D. Ramdin"
  30. AU="Hao, Zehui"
  31. AU="Chauhan, Aman"

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  1. Buch: Seizures and epilepsy in childhood

    Freeman, John Mark / Vining, Eileen P. G / Pillas, Diana J

    a guide

    (Johns Hopkins Press health book)

    2002  

    Verfasserangabe John M. Freeman, Eileen P.G. Vining, Diana J. Pillas
    Serientitel Johns Hopkins Press health book
    Mesh-Begriff(e) Epilepsy ; Child ; Infant ; Seizures
    Sprache Englisch
    Umfang xxvii, 395 p. :, ill. ;, 24 cm.
    Ausgabenhinweis 3rd ed.
    Verlag Johns Hopkins University Press
    Erscheinungsort Baltimore, Md
    Dokumenttyp Buch
    ISBN 9780801870507 ; 080187050X ; 9780801870514 ; 0801870518
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  2. Artikel: The importance of parental expectations of cognitive improvement for their children with epilepsy prior to starting the ketogenic diet.

    Farasat, Sharifeh / Kossoff, Eric H / Pillas, Diana J / Rubenstein, James E / Vining, Eileen P / Freeman, John M

    Epilepsy & behavior : E&B

    2006  Band 8, Heft 2, Seite(n) 406–410

    Abstract: Although the success rates and complications of various treatment options for children with intractable epilepsy have been described, the actual expectations of parents for these treatments are less clear. Since 1998, parents at our institution have ... ...

    Abstract Although the success rates and complications of various treatment options for children with intractable epilepsy have been described, the actual expectations of parents for these treatments are less clear. Since 1998, parents at our institution have written their goals in a letter before starting their children on the ketogenic diet. One hundred consecutive letters were evaluated. The most common first goal was seizure improvement, second was anticonvulsant reduction, and third was cognitive improvement. Ninety percent requested improvement in cognition or alertness. These expectations were either met or exceeded at 6 months in 52-60% of children. Achieving or surpassing parental expectations for cognitive improvement correlated with longer diet duration (P=0.04), but meeting goals for seizure or anticonvulsant reduction did not. Cognitive improvement (P<0.001) and >90% seizure reduction (P=0.04) at 6 months positively correlated with longer eventual diet duration. Expectations for cognitive improvement need to be discussed prior to beginning the ketogenic diet.
    Mesh-Begriff(e) Anticonvulsants/therapeutic use ; Attitude ; Child ; Cognition/physiology ; Dietary Fats/therapeutic use ; Epilepsy/diet therapy ; Epilepsy/drug therapy ; Epilepsy/psychology ; Female ; Goals ; Humans ; Ketosis/metabolism ; Male ; Parents/psychology
    Chemische Substanzen Anticonvulsants ; Dietary Fats
    Sprache Englisch
    Erscheinungsdatum 2006-03
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2005.12.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy.

    Kossoff, Eric H / McGrogan, Jane R / Bluml, Renee M / Pillas, Diana J / Rubenstein, James E / Vining, Eileen P

    Epilepsia

    2006  Band 47, Heft 2, Seite(n) 421–424

    Abstract: Purpose: The Atkins diet may induce ketosis as does the ketogenic diet, without restrictions on calories, fluids, protein, or need for an inpatient fast and admission. Our objective was to evaluate the efficacy and tolerability of a modified Atkins diet ...

    Abstract Purpose: The Atkins diet may induce ketosis as does the ketogenic diet, without restrictions on calories, fluids, protein, or need for an inpatient fast and admission. Our objective was to evaluate the efficacy and tolerability of a modified Atkins diet for intractable childhood epilepsy.
    Methods: Twenty children were treated prospectively in a hospital-based ambulatory clinic from September 2003 to May 2005. Children aged 3-18 years, with at least three seizures per week, who had been treated with at least two anticonvulsants, were enrolled and received the diet over a 6-month period. Carbohydrates were initially limited to 10 g/day, and fats were encouraged. Parents measured urinary ketones semiweekly and recorded seizures daily. All children received vitamin and calcium supplementation.
    Results: In all children, at least moderate urinary ketosis developed within 4 days (mean, 1.9). Sixteen (80%) completed the 6-month study; 14 chose to remain on the diet afterward. At 6 months, 13 (65%) had >50% improvement, and seven (35%) had >90% improvement (four were seizure free). Mean seizure frequency after 6 months was 40 per week (p = 0.005). Over a 6-month period, mean serum blood urea nitrogen increased from 12 to 17 mg/dl (p = 0.01); creatinine was unchanged. Cholesterol increased from 192 to 221 mg/dl, (p = 0.06). Weight did not change significantly (34.0-33.7 kg); only six children lost weight. A stable body mass index over time correlated with >90% improvement (p = 0.004).
    Conclusions: A modified Atkins diet is an effective and well-tolerated therapy for intractable pediatric epilepsy.
    Mesh-Begriff(e) Adolescent ; Age Factors ; Anticonvulsants/therapeutic use ; Blood Urea Nitrogen ; Child ; Child, Preschool ; Cholesterol/blood ; Creatinine/blood ; Diet, Carbohydrate-Restricted/methods ; Dietary Fats/administration & dosage ; Dietary Fats/metabolism ; Dietary Proteins/administration & dosage ; Dietary Proteins/metabolism ; Epilepsy/blood ; Epilepsy/diet therapy ; Epilepsy/metabolism ; Female ; Follow-Up Studies ; Humans ; Ketones/urine ; Ketosis/blood ; Ketosis/etiology ; Ketosis/urine ; Male ; Nitrogen/blood ; Treatment Outcome ; Weight Loss
    Chemische Substanzen Anticonvulsants ; Dietary Fats ; Dietary Proteins ; Ketones ; Cholesterol (97C5T2UQ7J) ; Creatinine (AYI8EX34EU) ; Nitrogen (N762921K75)
    Sprache Englisch
    Erscheinungsdatum 2006-02
    Erscheinungsland United States
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 216382-2
    ISSN 1528-1167 ; 0013-9580
    ISSN (online) 1528-1167
    ISSN 0013-9580
    DOI 10.1111/j.1528-1167.2006.00438.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Buch: Seizures and epilepsy in childhood

    Freeman, John Mark / Vining, Eileen P. G / Pillas, Diana J

    a guide for parents

    (A Johns Hopkins Press health book)

    1997  

    Verfasserangabe John M. Freeman, Eileen P.G. Vining, Diana J. Pillas
    Serientitel A Johns Hopkins Press health book
    Mesh-Begriff(e) Epilepsy ; Child ; Infant ; Seizures
    Sprache Englisch
    Umfang xxiii, 320 p. :, ill. ;, 24 cm.
    Ausgabenhinweis 2nd ed.
    Verlag Johns Hopkins University Press
    Erscheinungsort Baltimore
    Dokumenttyp Buch
    Anmerkung Includes index.
    ISBN 9780801854972 ; 0801854970 ; 9780801854989 ; 0801854989
    Datenquelle Katalog der US National Library of Medicine (NLM)

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