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  1. Book ; Online ; E-Book: Comprehensive geriatric assessment

    Pilotto, Alberto / Martin, Finbarr C.

    (Practical issues in geriatrics)

    2018  

    Author's details Alberto Pilotto, Finbarr C. Martin editors
    Series title Practical issues in geriatrics
    Keywords Medicine ; General practice (Medicine) ; Nephrology ; Geriatrics ; Oncology ; Surgery
    Subject code 618.97 ; 612.67
    Language English
    Size 1 Online-Ressource (VIII, 181 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019583021
    ISBN 978-3-319-62503-4 ; 9783319625027 ; 3-319-62503-9 ; 3319625020
    DOI 10.1007/978-3-319-62503-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Looking for lights in the fog of long-term neurological COVID.

    Padovani, Alessandro / Pilotto, Andrea

    Nature reviews. Neurology

    2023  Volume 19, Issue 1, Page(s) 7–8

    MeSH term(s) Humans ; COVID-19 ; Post-Acute COVID-19 Syndrome
    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2491514-2
    ISSN 1759-4766 ; 1759-4758
    ISSN (online) 1759-4766
    ISSN 1759-4758
    DOI 10.1038/s41582-022-00750-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Identifying Subtle Motor Deficits Before Parkinson's Disease is Diagnosed: What to Look for?

    Maetzler, Walter / Mirelman, Anat / Pilotto, Andrea / Bhidayasiri, Roongroj

    Journal of Parkinson's disease

    2024  

    Abstract: Motor deficits typical of Parkinson's disease (PD), such as gait and balance disturbances, tremor, reduced arm swing and finger movement, and voice and breathing changes, are believed to manifest several years prior to clinical diagnosis. Here we ... ...

    Abstract Motor deficits typical of Parkinson's disease (PD), such as gait and balance disturbances, tremor, reduced arm swing and finger movement, and voice and breathing changes, are believed to manifest several years prior to clinical diagnosis. Here we describe the evidence for the presence and progression of motor deficits in this pre-diagnostic phase in order to provide suggestions for the design of future observational studies for an effective, quantitatively oriented investigation. On the one hand, these future studies must detect these motor deficits in as large (potentially, population-based) cohorts as possible with high sensitivity and specificity. On the other hand, they must describe the progression of these motor deficits in the pre-diagnostic phase as accurately as possible, to support the testing of the effect of pharmacological and non-pharmacological interventions. Digital technologies and artificial intelligence can substantially accelerate this process.
    Language English
    Publishing date 2024-02-15
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2620609-2
    ISSN 1877-718X ; 1877-7171
    ISSN (online) 1877-718X
    ISSN 1877-7171
    DOI 10.3233/JPD-230350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6964: Show issues Location:
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  4. Book: Aging and the gastrointestinal tract

    Pilotto, Alberto

    20 tabels

    (Interdisciplinary topics in gerontology ; 32)

    2003  

    Author's details Vol. ed. Alberto Pilotto
    Series title Interdisciplinary topics in gerontology ; 32
    Collection
    Keywords Gastrointestinal Diseases ; Aging / physiology ; Gastrointestinal System ; Aged ; Alter ; Gastrointestinale Krankheit
    Subject Magen-Darm-Krankheit ; Magen-Darm-Kanal ; Alter Mensch ; Betagter ; Senioren ; Senior
    Language English
    Size VIII, 218 S.: Ill., graph. Darst., 18 schw.-w. u. 2 farb. Abb., 20 schw.-w. Tab., 245 mm x 175 mm
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT013754027
    ISBN 3-8055-7555-6 ; 978-3-8055-7555-3
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2003 A 2740 order for loan Magazin

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  5. Article ; Online: Vortioxetine Treatment for Depression in Patients with Prodromal vs Mild Alzheimer's Disease: A Six-Month, Open-Label, Observational Study.

    Padovani, A / Caratozzolo, S / Benussi, A / Galli, A / Rozzini, L / Cosseddu, M / Turrone, R / Pilotto, A

    The journal of prevention of Alzheimer's disease

    2024  Volume 11, Issue 2, Page(s) 375–381

    Abstract: Background: Depressive symptoms are common in Alzheimer disease (AD) from the prodromal stage. The benefits of antidepressants have been investigated in patients with AD dementia with mixed results.: Objectives: This study aimed to compare the ... ...

    Abstract Background: Depressive symptoms are common in Alzheimer disease (AD) from the prodromal stage. The benefits of antidepressants have been investigated in patients with AD dementia with mixed results.
    Objectives: This study aimed to compare the efficacy of vortioxetine in prodromal and mild-to-moderate AD patients with depression, and to assess the comparative effect on secondary measures, including behavioral disturbances, cognitive function, and activities of daily living.
    Participants: All subjects with AD at a single-center dementia center underwent a standard evaluation with mini-mental state examination (MMSE), basic and instrumental activities of daily living (BADL and IADL), geriatric depression scale (GDS), neuropsychiatric inventory (NPI), and clinical evaluation every six months.
    Measurements: The study specifically assessed patients on vortioxetine with available six-month follow-up data. The changes in GDS, NPI, MMSE, BADL/IADL at six months in the entire AD population and mild-to-moderate AD vs prodromal population were analyzed using repeated measure multivariate analyses. Linear regression analyses were implemented to evaluate baseline demographics and clinical characteristics associated with depressive and cognitive improvements at six months.
    Results: Out of 680 AD patients, 115 were treated with vortioxetine, and 89 with six-month follow-up data were included in the analyses. A significant improvement at follow-up was observed for GDS, NPI total and sub score items (mood, anxiety, apathy, sleep disturbances, eating abnormalities). Both mild-to-moderate and prodromal AD showed a positive GDS response, whereas mild-to-moderate AD showed a better improvement on total NPI and apathy/nighttime behaviors subitems compared to prodromal AD. Higher baseline GDS score was the only variable associated with higher responses in linear regression analyses. MMSE showed a significant improvement at six months in the entire cohort, with a greater effect in prodromal vs mild-to-moderate AD. Cognitive improvement (i.e., MMSE changes) was associated with cognitive status at baseline but independent of the antidepressant/behavioral changes (i.e., GDS/NPI).
    Conclusions: Our results suggest that vortioxetine is highly tolerable and clinically effective in both prodromal and mild-to-moderate AD with depression. Patients with mild-to-moderate AD benefited more from a wide range of behavioral disturbances. The study also showed significant improvement in global cognitive measures, especially in prodromal AD subjects. Further studies are needed to investigate the independent beneficial effect of vortioxetine on depression and cognition in AD.
    MeSH term(s) Humans ; Aged ; Alzheimer Disease/complications ; Alzheimer Disease/drug therapy ; Alzheimer Disease/psychology ; Vortioxetine/therapeutic use ; Depression/complications ; Depression/drug therapy ; Activities of Daily Living ; Antidepressive Agents/therapeutic use
    Chemical Substances Vortioxetine (3O2K1S3WQV) ; Antidepressive Agents
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Observational Study ; Journal Article
    ZDB-ID 2782183-3
    ISSN 2426-0266 ; 2274-5807
    ISSN (online) 2426-0266
    ISSN 2274-5807
    DOI 10.14283/jpad.2023.132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Towards the use of new technologies for nutritional safety

    Pilotto, A

    2016  

    Author's details A. Pilotto
    Language English
    Size Online-Ressource
    Publishing place Milano
    Document type Book ; Online
    Database Special collection on veterinary medicine and general parasitology

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  7. Article: The challenge of the multifaceted prognosis in the older people and the Multidimensional Prognostic Index.

    Mattace-Raso, Francesco / Pilotto, Alberto

    European geriatric medicine

    2021  Volume 12, Issue 2, Page(s) 223–226

    MeSH term(s) Aged ; Geriatric Assessment ; Humans ; Independent Living ; Prognosis
    Language English
    Publishing date 2021-02-23
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 2556794-9
    ISSN 1878-7657 ; 1878-7649
    ISSN (online) 1878-7657
    ISSN 1878-7649
    DOI 10.1007/s41999-021-00457-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Digital assessment at home - mPower against Parkinson disease.

    Maetzler, Walter / Pilotto, Andrea

    Nature reviews. Neurology

    2021  Volume 17, Issue 11, Page(s) 661–662

    MeSH term(s) Cell Phone ; Home Care Services ; Humans ; Mobile Applications ; Parkinson Disease/therapy ; Patient Selection ; Reproducibility of Results ; Research Design
    Language English
    Publishing date 2021-10-05
    Publishing country England
    Document type News
    ZDB-ID 2491514-2
    ISSN 1759-4766 ; 1759-4758
    ISSN (online) 1759-4766
    ISSN 1759-4758
    DOI 10.1038/s41582-021-00567-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Looking at the burden of neurological disorders in Europe.

    Padovani, Alessandro / Pilotto, Andrea

    The Lancet. Public health

    2020  Volume 5, Issue 10, Page(s) e523

    MeSH term(s) Europe/epidemiology ; Global Burden of Disease ; Humans ; Mental Disorders ; Nervous System Diseases/epidemiology
    Language English
    Publishing date 2020-10-02
    Publishing country England
    Document type Letter ; Comment
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(20)30205-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to the Letter "COVID-19-Associated Encephalopathy and Cytokine-Mediated Neuroinflammation".

    Pilotto, Andrea / Padovani, Alessandro

    Annals of neurology

    2020  Volume 88, Issue 4, Page(s) 861–862

    MeSH term(s) Betacoronavirus ; Brain Diseases ; COVID-19 ; Coronavirus Infections ; Cytokines ; Humans ; Inflammation ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances Cytokines
    Keywords covid19
    Language English
    Publishing date 2020-08-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.25856
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 478: Show issues

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