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  1. Book ; Online ; E-Book: Angiotensin

    Pilowsky, Paul M.

    from the kidney to coronavirus

    (Molecular mediators in health and disease)

    2023  

    Author's details edited by Paul M. Pilowsky
    Series title Molecular mediators in health and disease
    Keywords Angiotensins
    Subject code 615.71
    Language English
    Size 1 Online-Ressource (xxxiv, 789 Seiten), Illustrationen
    Publisher Elsevier Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021732093
    ISBN 978-0-323-99619-8 ; 9780323996181 ; 0-323-99619-1 ; 0323996183
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Serotonin

    Pilowsky, Paul M.

    the mediator that spans evolution

    2019  

    Author's details edited by Paul M Pilowsky
    Keywords Serotonin ; Evolution (Biology)
    Subject code 612.8/042
    Language English
    Size 1 Online-Ressource (xix, 430 Seiten), Illustrationen, Diagramme
    Publisher Academic Press, an imprint of Elsevier
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019851154
    ISBN 978-0-12-800584-2 ; 9780128000502 ; 0-12-800584-X ; 0128000503
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Illuminating the mechanisms underlying obstructive sleep apnea.

    Pilowsky, Paul M

    Acta physiologica (Oxford, England)

    2022  Volume 236, Issue 3, Page(s) e13883

    MeSH term(s) Humans ; Sleep Apnea, Obstructive ; Risk Factors
    Language English
    Publishing date 2022-09-07
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2218636-0
    ISSN 1748-1716 ; 1748-1708
    ISSN (online) 1748-1716
    ISSN 1748-1708
    DOI 10.1111/apha.13883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Stimulation and inhibition of neurons

    Pilowsky, Paul M. / Farnham, Melissa M. J. / Fong, Angelina Y.

    (Neuromethods ; 78)

    2013  

    Author's details ed. by Paul M. Pilowsky ; Melissa M.J. Farnham ; Angelina Y. Fong
    Series title Neuromethods ; 78
    Collection
    Keywords Neurons
    Language English
    Size XII, 319 S. : zahlr. Ill., graph. Darst., 22 cm
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017485149
    ISBN 978-1-62703-232-2 ; 9781627032339 ; 1-62703-232-0 ; 1627032339
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2012 A 4524 order for loan Magazin

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  5. Article ; Online: Foreword.

    Pilowsky, Paul M

    Respiratory physiology & neurobiology

    2016  Volume 226, Page(s) 1–2

    Language English
    Publishing date 2016-06
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2077867-3
    ISSN 1878-1519 ; 1569-9048
    ISSN (online) 1878-1519
    ISSN 1569-9048
    DOI 10.1016/j.resp.2016.03.016
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  6. Article ; Online: Peptides, serotonin, and breathing: the role of the raphe in the control of respiration.

    Pilowsky, Paul M

    Progress in brain research

    2014  Volume 209, Page(s) 169–189

    Abstract: Over the last 20 years, it has become clear that many functionally defined autonomic neurons in the brainstem contain many more than one neurotransmitter. Here, the possible role and functions of colocalized neuropeptides in the caudal raphe nuclei of ... ...

    Abstract Over the last 20 years, it has become clear that many functionally defined autonomic neurons in the brainstem contain many more than one neurotransmitter. Here, the possible role and functions of colocalized neuropeptides in the caudal raphe nuclei of the medulla oblongata are discussed. Caudal raphe neurons provide an extensive input to neurons throughout the brainstem and spinal cord, including respiratory and cardiovascular neurons. It is concluded that one plausible function of colocalized neuropeptides is to maintain the membrane potential of target neurons within a defined window so that they remain able to function at extremes of activity.
    MeSH term(s) Animals ; Humans ; Membrane Potentials/physiology ; Neurons/physiology ; Neuropeptides/metabolism ; Raphe Nuclei/physiology ; Respiration ; Serotonin/metabolism
    Chemical Substances Neuropeptides ; Serotonin (333DO1RDJY)
    Language English
    Publishing date 2014
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 1875-7855 ; 0079-6123
    ISSN (online) 1875-7855
    ISSN 0079-6123
    DOI 10.1016/B978-0-444-63274-6.00009-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A simple, novel and accurate method to estimate track record: a new "P" value.

    Pilowsky, Paul M

    The Medical journal of Australia

    2014  Volume 201, Issue 9, Page(s) 549

    MeSH term(s) Humans ; Mathematical Concepts ; Research Support as Topic
    Language English
    Publishing date 2014-05-13
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja14.00231
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  8. Article ; Online: Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women's Health Initiative.

    Pilowsky, Paul M

    Cancer

    2013  Volume 119, Issue 20, Page(s) 3737

    MeSH term(s) Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Aspirin/administration & dosage ; European Continental Ancestry Group/statistics & numerical data ; Female ; Humans ; Melanoma/epidemiology
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2013-10-15
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.28248
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  9. Article ; Online: Carbohydrate ingestion induces differential autonomic dysregulation in normal-tension glaucoma and primary open angle glaucoma.

    Cao, Lei / Graham, Stuart L / Pilowsky, Paul M

    PloS one

    2018  Volume 13, Issue 6, Page(s) e0198432

    Abstract: Background: It is reported that glaucoma may be associated with vascular dysregulation. Normal tension glaucoma (NTG) and primary open angle glaucoma (POAG), which feature different intraocular pressure levels, may manifest differential features of ... ...

    Abstract Background: It is reported that glaucoma may be associated with vascular dysregulation. Normal tension glaucoma (NTG) and primary open angle glaucoma (POAG), which feature different intraocular pressure levels, may manifest differential features of systemic autonomic dysregulation.
    Methods and results: We investigated autonomic regulation to carbohydrate ingestion and postural change in 37 glaucoma patients (19 NTG and 18 POAG) and 36 controls. Subjects were age and gender-matched, normotensive, and had normal comparable insulin sensitivity. Continuous finger arterial pressure and ECG was recorded in supine and standing positions before and after carbohydrate ingestion. Low frequency (LF, 0.04-0.15Hz) and high frequency (HF, 0.15-0.4Hz) spectral power of heart rate and systolic blood pressure variability (HRV and SBPV) were calculated to estimate sympathovagal function. Overall comparison glaucoma (N = 37) and controls (N = 36) showed an increased sympathetic excitation, vagal withdrawal and unstable mean arterial pressure after carbohydrate ingestion in glaucoma patients. Glaucoma severity by retinal nerve fibre layer (RNFL) thickness is positively correlated to autonomic responses (HRV LF power and HF power in normalised units (nu), and HRV LF/HF ratio) after carbohydrate ingestion. Early (30 minutes) following carbohydrate ingestion, SBP LF power and HRV parameters remained unchanged in controls; while POAG showed abnormal autonomic responses, with a paradoxical vagal enhancement (increased HRV HF power in nu) and sympathetic inhibition (decreased HRV LF power nu and HRV LF/HF ratio), and associated hypotension. Later (60-120 minutes) following carbohydrate ingestion, HRV parameters remained unaltered in controls; whereas NTG manifested vagal withdrawal (reduced HRV HF power nu) and sympathetic hyper-responsiveness (increased HRV LF power nu and HRV LF/HF ratio), despite increased SBP LF power in both controls and NTG. Both NTG and POAG exhibited attenuated autonomic responses to postural stress.
    Conclusions: NTG and POAG both manifest some systemic autonomic cardiovascular dysregulation. However, the two forms of glaucoma respond differentially to carbohydrate ingestion, irrespective of insulin resistance.
    MeSH term(s) Aged ; Aged, 80 and over ; Autonomic Nervous System/drug effects ; Autonomic Nervous System/physiology ; Blood Pressure/drug effects ; Carbohydrates/pharmacology ; Case-Control Studies ; Diet ; Electrocardiography ; Female ; Glaucoma, Open-Angle/physiopathology ; Heart Rate/drug effects ; Hemodynamics/drug effects ; Humans ; Low Tension Glaucoma/physiopathology ; Male ; Middle Aged ; Postural Balance ; Retina/physiology ; Severity of Illness Index
    Chemical Substances Carbohydrates
    Language English
    Publishing date 2018-06-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0198432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Every breath you take: why sympathetic nerve activity comes in bursts.

    Pilowsky, Paul M

    The Journal of physiology

    2009  Volume 587, Issue 2, Page(s) 297

    MeSH term(s) Animals ; Blood Pressure/physiology ; Cardiovascular Physiological Phenomena ; Hypoxia/physiopathology ; Medulla Oblongata/cytology ; Medulla Oblongata/physiology ; Neurons/physiology ; Rats ; Respiratory Burst/physiology ; Respiratory Physiological Phenomena ; Sympathetic Nervous System/physiology
    Language English
    Publishing date 2009-01-15
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/jphysiol.2008.167205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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