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Article ; Online: Percutaneous treatment of symptomatic deep vein thrombosis in adolescents using large-bore thrombectomy systems.

Monroe, Eric J / Woods, Michael A / Shin, David S / Reis, Joseph / Swietlik, John / Eifler, Aaron / Pinchot, Jason W / Chick, Jeffrey Forris Beecham

Pediatric radiology

2023 Volume 53, Issue 13, Page(s) 2692–2698

Abstract: Background: While large-bore mechanical thrombectomy provides effective venous thrombus removal, often with avoidance of thrombolytics, literature surrounding the application of these devices in pediatric patients is sparse.: Objective: To report ... ...

Abstract	Background: While large-bore mechanical thrombectomy provides effective venous thrombus removal, often with avoidance of thrombolytics, literature surrounding the application of these devices in pediatric patients is sparse. Objective: To report technical success and outcomes following large-bore thrombectomy systems in adolescent patients with deep venous thrombosis. Materials and methods: A retrospective review identified all patients less than 18 years of age undergoing mechanical venous thrombectomy at a single institution between 2018 and 2022. No patients were excluded. Technical success was defined as extraction of thrombus sufficient to restore unimpeded flow in affected segments. Clinical success was defined as resolution of presenting symptoms. Results: Nine consecutive patients (6 females, 3 males; age range 15-17 years) underwent 10 thrombectomy procedures using ClotTriever (n=6; 60%), FlowTriever (n=2; 20%), or both (n=2; 20%). Chronicity of thrombus was categorized as acute (<2 weeks) in 6 (60%), subacute (2-6 weeks) in 1 (10%), and chronic (>6 weeks) in 3 (30%). Distribution of thrombus was lower extremity and/or inferior vena cava (IVC) in 9 (90%) and unilateral axillo-subclavian in 1 (10%). Technical success was achieved in 9 interventions (90%). Clinical success was achieved in 8 patients (88.9%). No patients received thrombolytics. There were no intraprocedural adverse events (AE). Minor complications (Society of Interventional Radiology mild adverse events) were observed in a delayed fashion following 2 interventions (20%). Conclusions: This preliminary experience demonstrated high rates of technical and clinical success with large-bore deep venous thrombectomy in adolescent patients across a range of thrombus chronicity and locations.
MeSH term(s)	Male ; Female ; Humans ; Adolescent ; Child ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/surgery ; Thrombectomy/methods ; Lower Extremity/blood supply ; Fibrinolytic Agents ; Vena Cava, Inferior ; Retrospective Studies ; Treatment Outcome ; Thrombolytic Therapy/methods
Chemical Substances	Fibrinolytic Agents
Language	English
Publishing date	2023-10-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	124459-0
ISSN	1432-1998 ; 0301-0449
ISSN (online)	1432-1998
ISSN	0301-0449
DOI	10.1007/s00247-023-05785-5
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Article ; Online: Imaging to intervention: a review of what the Interventionalist needs to Know about Hereditary Hemorrhagic Telangiectasia.

Sobrepera, Stephanie / Monroe, Eric / Gemmete, Joseph J / Hallam, Danial / Pinchot, Jason W / Kaufman, Claire

CVIR endovascular

2021 Volume 4, Issue 1, Page(s) 84

Abstract: Hereditary hemorrhagic telangiectasia (HHT) is a disorder that affects 1 in 5000-10,000 people worldwide and can result in devastating complications such as cerebral abscess, stroke, massive hemorrhage, and even death. HHT is an autosomal dominant ... ...

Abstract	Hereditary hemorrhagic telangiectasia (HHT) is a disorder that affects 1 in 5000-10,000 people worldwide and can result in devastating complications such as cerebral abscess, stroke, massive hemorrhage, and even death. HHT is an autosomal dominant disorder that leads to the formation of abnormal communication between the arteries and veins with a resultant spectrum of vascular anomalies. The disorder affects many organ systems and thus requires a dedicated multidisciplinary approach. Interventional radiologists are vital members of this team providing expertise not only in disease management, but in complex embolotherapy, helping to maintain the health of these patients. This article reviews clinical manifestations, screening guidelines, diagnostic criteria, and endovascular management of HHT.
Language	English
Publishing date	2021-12-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ISSN	2520-8934
ISSN (online)	2520-8934
DOI	10.1186/s42155-021-00270-2
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Article ; Online: ACR Appropriateness Criteria® Management of Liver Cancer: 2022 Update.

Knavel Koepsel, Erica M / Smolock, Amanda R / Pinchot, Jason W / Kim, Charles Y / Ahmed, Osmanuddin / Chamarthy, Murthy R K / Hecht, Elizabeth M / Hwang, Gloria L / Kaplan, David E / Luh, Join Y / Marrero, Jorge A / Monroe, Eric J / Poultsides, George A / Scheidt, Matthew J / Hohenwalter, Eric J

Journal of the American College of Radiology : JACR

2022 Volume 19, Issue 11S, Page(s) S390–S408

Abstract: The treatment and management of hepatic malignancies can be complex because it encompasses a variety of primary and metastatic malignancies and an assortment of local and systemic treatment options. When to use each of these treatments is critical to ... ...

Abstract	The treatment and management of hepatic malignancies can be complex because it encompasses a variety of primary and metastatic malignancies and an assortment of local and systemic treatment options. When to use each of these treatments is critical to ensure the most appropriate care for patients. Interventional radiologists have a key role to play in the delivery of a variety of liver directed treatments including percutaneous ablation, transarterial embolization with bland embolic particles alone, transarterial chemoembolization (TACE) with injection of a chemotherapeutic emulsion, and transarterial radioembolization (TARE). Based on 9 clinical variants, the appropriateness of each treatment is described in this document. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision process support the systematic analysis of the medical literature from peer reviewed journals. Established methodology principles such as Grading of Recommendations Assessment, Development, and Evaluation or GRADE are adapted to evaluate the evidence. The RAND/UCLA Appropriateness Method User Manual provides the methodology to determine the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances in which peer reviewed literature is lacking or equivocal, experts may be the primary evidentiary source available to formulate a recommendation.
MeSH term(s)	Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/therapy ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/therapy ; Chemoembolization, Therapeutic ; Brachytherapy ; Radiologists
Language	English
Publishing date	2022-11-24
Publishing country	United States
Document type	Practice Guideline ; Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2022.09.005
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Article ; Online: ACR Appropriateness Criteria® Thoracoabdominal Aortic Aneurysm or Dissection: Treatment Planning and Follow-Up.

Journal of the American College of Radiology : JACR

2023 Volume 20, Issue 5S, Page(s) S265–S284

Abstract: As the incidence of thoracoabdominal aortic pathology (aneurysm and dissection) rises and the complexity of endovascular and surgical treatment options increases, imaging follow-up of patients remains crucial. Patients with thoracoabdominal aortic ... ...

Abstract	As the incidence of thoracoabdominal aortic pathology (aneurysm and dissection) rises and the complexity of endovascular and surgical treatment options increases, imaging follow-up of patients remains crucial. Patients with thoracoabdominal aortic pathology without intervention should be monitored carefully for changes in aortic size or morphology that could portend rupture or other complication. Patients who are post endovascular or open surgical aortic repair should undergo follow-up imaging to evaluate for complications, endoleak, or recurrent pathology. Considering the quality of diagnostic data, CT angiography and MR angiography are the preferred imaging modalities for follow-up of thoracoabdominal aortic pathology for most patients. The extent of thoracoabdominal aortic pathology and its potential complications involve multiple regions of the body requiring imaging of the chest, abdomen, and pelvis in most patients. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision process support the systematic analysis of the medical literature from peer reviewed journals. Established methodology principles such as Grading of Recommendations Assessment, Development, and Evaluation or GRADE are adapted to evaluate the evidence. The RAND/UCLA Appropriateness Method User Manual provides the methodology to determine the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where peer reviewed literature is lacking or equivocal, experts may be the primary evidentiary source available to formulate a recommendation.
MeSH term(s)	Humans ; United States ; Aortic Aneurysm, Thoracoabdominal ; Follow-Up Studies ; Societies, Medical ; Evidence-Based Medicine ; Angiography
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Practice Guideline ; Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2023.02.007
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Article ; Online: ACR Appropriateness Criteria® Management of Vertebral Compression Fractures: 2022 Update.

Journal of the American College of Radiology : JACR

2023 Volume 20, Issue 5S, Page(s) S102–S124

Abstract: Vertebral compression fractures (VCFs) can have a variety of etiologies, including trauma, osteoporosis, or neoplastic infiltration. Osteoporosis related fractures are the most common cause of VCFs and have a high prevalence among all postmenopausal ... ...

Abstract	Vertebral compression fractures (VCFs) can have a variety of etiologies, including trauma, osteoporosis, or neoplastic infiltration. Osteoporosis related fractures are the most common cause of VCFs and have a high prevalence among all postmenopausal women with increasing incidence in similarly aged men. Trauma is the most common etiology in those >50 years of age. However, many cancers, such as breast, prostate, thyroid, and lung, have a propensity to metastasize to bone, which can lead to malignant VCFs. Indeed, the spine is third most common site of metastases after lung and liver. In addition, primary tumors of bone and lymphoproliferative diseases such as lymphoma and multiple myeloma can be the cause of malignant VCFs. Although patient clinical history could help raising suspicion for a particular disorder, the characterization of VCFs is usually referred to diagnostic imaging. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances in which evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
MeSH term(s)	Male ; Humans ; Female ; United States ; Aged ; Spinal Fractures/diagnostic imaging ; Spinal Fractures/therapy ; Fractures, Compression/diagnostic imaging ; Fractures, Compression/therapy ; Osteoporosis ; Bone and Bones ; Societies, Medical
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Practice Guideline ; Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2023.02.015
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Article ; Online: Isolated intrapulmonary teratoma.

Ditah, Callistus / Templin, Thomas / Mandal, Rakesh / Pinchot, Jason W / Macke, Ryan A

The Journal of thoracic and cardiovascular surgery

2016 Volume 152, Issue 6, Page(s) e129–e131

MeSH term(s)	Angiography ; Female ; Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/surgery ; Teratoma/diagnostic imaging ; Teratoma/surgery ; Thoracic Surgery, Video-Assisted ; Thoracotomy ; Tomography, X-Ray Computed ; Young Adult
Language	English
Publishing date	2016
Publishing country	United States
Document type	Case Reports ; Journal Article ; Video-Audio Media
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2016.07.056
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Article ; Online: ACR Appropriateness Criteria® Radiologic Management of Urinary Tract Obstruction.

Scheidt, Matthew J / Hohenwalter, Eric J / Pinchot, Jason W / Ahmed, Osmanuddin / Bjurlin, Marc A / Braun, Aaron R / Kim, Charles Y / Knavel Koepsel, Erica M / Schramm, Kristofer / Sella, David M / Weiss, Clifford R / Lorenz, Jonathan M

Journal of the American College of Radiology : JACR

2020 Volume 17, Issue 5S, Page(s) S281–S292

Abstract: Acute obstructive uropathy is a medical emergency, which often is accompanied by acute renal failure or sepsis. Treatment options to resolve the acute obstructive process include conservative medical management, retrograde ureteral stenting, or placement ...

Abstract	Acute obstructive uropathy is a medical emergency, which often is accompanied by acute renal failure or sepsis. Treatment options to resolve the acute obstructive process include conservative medical management, retrograde ureteral stenting, or placement of percutaneous nephrostomy or nephroureteral catheters. It is important to understand the various treatment options in differing clinical scenarios in order to guide appropriate consultation. Prompt attention to the underlying obstructive process is often imperative to avoid further deterioration of the patient's clinical status. A summary of the data and most up-to-date clinical trials regarding treatment options for urinary tract obstruction is outlined in this publication. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
MeSH term(s)	Diagnostic Imaging ; Evidence-Based Medicine ; Humans ; Radiology ; Societies, Medical ; United States ; Urinary Tract
Language	English
Publishing date	2020-04-30
Publishing country	United States
Document type	Practice Guideline ; Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2020.01.039
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Article ; Online: ACR Appropriateness Criteria® Radiologic Management of Portal Hypertension.

Pinchot, Jason W / Kalva, Sanjeeva P / Majdalany, Bill S / Kim, Charles Y / Ahmed, Osmanuddin / Asrani, Sumeet K / Cash, Brooks D / Eldrup-Jorgensen, Jens / Kendi, A Tuba / Scheidt, Matthew J / Sella, David M / Dill, Karin E / Hohenwalter, Eric J

Journal of the American College of Radiology : JACR

2021 Volume 18, Issue 5S, Page(s) S153–S173

Abstract: Cirrhosis is a heterogeneous disease that cannot be studied as a single entity and is classified in two main prognostic stages: compensated and decompensated cirrhosis. Portal hypertension, characterized by a pathological increase of the portal pressure ... ...

Abstract	Cirrhosis is a heterogeneous disease that cannot be studied as a single entity and is classified in two main prognostic stages: compensated and decompensated cirrhosis. Portal hypertension, characterized by a pathological increase of the portal pressure and by the formation of portal-systemic collaterals that bypass the liver, is the initial and main consequence of cirrhosis and is responsible for the majority of its complications. A myriad of treatment options exists for appropriately managing the most common complications of portal hypertension, including acute variceal bleeding and refractory ascites. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
MeSH term(s)	Esophageal and Gastric Varices ; Evidence-Based Medicine ; Gastrointestinal Hemorrhage ; Humans ; Radiology ; Societies, Medical ; United States
Language	English
Publishing date	2021-06-01
Publishing country	United States
Document type	Practice Guideline ; Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2021.02.013
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Article ; Online: Novel findings and expansion of phenotype in a mosaic RASopathy caused by somatic KRAS variants.

Chang, Caitlin A / Perrier, Renee / Kurek, Kyle C / Estrada-Veras, Juvianee / Lehman, Anna / Yip, Stephen / Hendson, Glenda / Diamond, Carol / Pinchot, Jason W / Tran, Jennifer M / Arkin, Lisa M / Drolet, Beth A / Napier, Melanie P / O'Neill, Sarah A / Balci, Tugce B / Keppler-Noreuil, Kim M

American journal of medical genetics. Part A

2021 Volume 185, Issue 9, Page(s) 2829–2845

Abstract: Mosaic KRAS variants and other RASopathy genes cause oculoectodermal, encephalo-cranio-cutaneous lipomatosis, and Schimmelpenning-Feuerstein-Mims syndromes, and a spectrum of vascular malformations, overgrowth and other associated anomalies, the latter ... ...

Abstract	Mosaic KRAS variants and other RASopathy genes cause oculoectodermal, encephalo-cranio-cutaneous lipomatosis, and Schimmelpenning-Feuerstein-Mims syndromes, and a spectrum of vascular malformations, overgrowth and other associated anomalies, the latter of which are only recently being characterized. We describe eight individuals in total (six unreported cases and two previously reported cases) with somatic KRAS variants and variably associated features. Given the findings of somatic overgrowth (in seven individuals) and vascular or lymphatic malformations (in eight individuals), we suggest mosaic RASopathies (mosaic KRAS variants) be considered in the differential diagnosis for individuals presenting with asymmetric overgrowth and lymphatic or vascular anomalies. We expand the association with embryonal tumors, including the third report of embryonal rhabdomyosarcoma, as well as novel findings of Wilms tumor and nephroblastomatosis in two individuals. Rare or novel findings in our series include the presence of epilepsy, polycystic kidneys, and T-cell deficiency in one individual, and multifocal lytic bone lesions in two individuals. Finally, we describe the first use of targeted therapy with a MEK inhibitor for an individual with a mosaic KRAS variant. The purposes of this report are to expand the phenotypic spectrum of mosaic KRAS-related disorders, and to propose possible mechanisms of pathogenesis, and surveillance of its associated findings.
MeSH term(s)	Abnormalities, Multiple/genetics ; Abnormalities, Multiple/pathology ; Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Male ; Mosaicism ; Mutation ; Phenotype ; Proto-Oncogene Proteins p21(ras)/genetics ; Vascular Malformations/genetics ; Vascular Malformations/pathology ; Wilms Tumor/genetics ; Wilms Tumor/pathology
Chemical Substances	KRAS protein, human ; Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2)
Language	English
Publishing date	2021-05-30
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2108614-X
ISSN	1552-4833 ; 0148-7299 ; 1552-4825
ISSN (online)	1552-4833
ISSN	0148-7299 ; 1552-4825
DOI	10.1002/ajmg.a.62356
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Article ; Online: ACR Appropriateness Criteria® Radiologic Management of Infected Fluid Collections.

Weiss, Clifford R / Bailey, Christopher R / Hohenwalter, Eric J / Pinchot, Jason W / Ahmed, Osmanuddin / Braun, Aaron R / Cash, Brooks D / Gupta, Samir / Kim, Charles Y / Knavel Koepsel, Erica M / Scheidt, Matthew J / Schramm, Kristofer / Sella, David M / Lorenz, Jonathan M

Journal of the American College of Radiology : JACR

2020 Volume 17, Issue 5S, Page(s) S265–S280

Abstract: Infected fluid collections are common and occur in a variety of clinical scenarios throughout the body. Minimally invasive image-guided management strategies for infected fluid collections are often preferred over more invasive options, given their low ... ...

Abstract	Infected fluid collections are common and occur in a variety of clinical scenarios throughout the body. Minimally invasive image-guided management strategies for infected fluid collections are often preferred over more invasive options, given their low rate of complications and high rates of success. However, specific clinical scenarios, anatomic considerations, and prior or ongoing treatments must be considered when determining the optimal management strategy. As such, several common scenarios relating to infected fluid collections were developed using evidence-based guidelines for management. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
MeSH term(s)	Diagnostic Imaging ; Evidence-Based Medicine ; Humans ; Peer Review ; Radiology ; Societies, Medical ; United States
Language	English
Publishing date	2020-04-30
Publishing country	United States
Document type	Practice Guideline ; Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2020.01.034
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