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Article ; Online: MONDO: a neutron tracker for particle therapy secondary emission characterisation.

Marafini, M / Gasparini, L / Mirabelli, R / Pinci, D / Patera, V / Sciubba, A / Spiriti, E / Stoppa, D / Traini, G / Sarti, A

Physics in medicine and biology

2017 Volume 62, Issue 8, Page(s) 3299–3312

Abstract: Tumour control is performed in particle therapy using particles and ions, whose high irradiation precision enhances the effectiveness of the treatment, while sparing the healthy tissue surrounding the target volume. Dose range monitoring devices using ... ...

Abstract	Tumour control is performed in particle therapy using particles and ions, whose high irradiation precision enhances the effectiveness of the treatment, while sparing the healthy tissue surrounding the target volume. Dose range monitoring devices using photons and charged particles produced by the beam interacting with the patient's body have already been proposed, but no attempt has been made yet to exploit the detection of the abundant neutron component. Since neutrons can release a significant dose far away from the tumour region, precise measurements of their flux, production energy and angle distributions are eagerly sought in order to improve the treatment planning system (TPS) software. It will thus be possible to predict not only the normal tissue toxicity in the target region, but also the risk of late complications in the whole body. The aforementioned issues underline the importance of an experimental effort devoted to the precise characterisation of neutron production, aimed at the measurement of their abundance, emission point and production energy. The technical challenges posed by a neutron detector aimed at high detection efficiency and good backtracking precision are addressed within the MONDO (monitor for neutron dose in hadrontherapy) project, whose main goal is to develop a tracking detector that can target fast and ultrafast neutrons. A full reconstruction of two consecutive elastic scattering interactions undergone by the neutrons inside the detector material will be used to measure their energy and direction. The preliminary results of an MC simulation performed using the FLUKA software are presented here, together with the DSiPM (digital SiPM) readout implementation. New detector readout implementations specifically tailored to the MONDO tracker are also discussed, and the neutron detection efficiency attainable with the proposed neutron tracking strategy are reported.
MeSH term(s)	Humans ; Neutrons/therapeutic use ; Radiation Dosimeters ; Radiotherapy/instrumentation ; Radiotherapy/methods ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted/methods ; Software
Language	English
Publishing date	2017-03-13
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208857-5
ISSN	1361-6560 ; 0031-9155
ISSN (online)	1361-6560
ISSN	0031-9155
DOI	10.1088/1361-6560/aa623a
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Article ; Online: Secondary radiation measurements for particle therapy applications: charged particles produced by

Physics in medicine and biology

2018 Volume 63, Issue 5, Page(s) 55018

Abstract: Proton and carbon ion beams are used in the clinical practice for external radiotherapy treatments achieving, for selected indications, promising and superior clinical results with respect to x-ray based radiotherapy. Other ions, like [Formula: see text] ...

Abstract	Proton and carbon ion beams are used in the clinical practice for external radiotherapy treatments achieving, for selected indications, promising and superior clinical results with respect to x-ray based radiotherapy. Other ions, like [Formula: see text] have recently been considered as projectiles in particle therapy centres and might represent a good compromise between the linear energy transfer and the radiobiological effectiveness of [Formula: see text] ion and proton beams, allowing improved tumour control probability and minimising normal tissue complication probability. All the currently used p, [Formula: see text] and [Formula: see text] ion beams allow achieving sharp dose gradients on the boundary of the target volume, however the accurate dose delivery is sensitive to the patient positioning and to anatomical variations with respect to photon therapy. This requires beam range and/or dose release measurement during patient irradiation and therefore the development of dedicated monitoring techniques. All the proposed methods make use of the secondary radiation created by the beam interaction with the patient and, in particular, in the case of [Formula: see text] ion beams are also able to exploit the significant charged radiation component. Measurements performed to characterise the charged secondary radiation created by [Formula: see text] and [Formula: see text] particle therapy beams are reported. Charged secondary yields, energy spectra and emission profiles produced in a poly-methyl methacrylate (PMMA) target by [Formula: see text] and [Formula: see text] beams of different therapeutic energies were measured at 60° and 90° with respect to the primary beam direction. The secondary yield of protons produced along the primary beam path in a PMMA target was obtained. The energy spectra of charged secondaries were obtained from time-of-flight information, whereas the emission profiles were reconstructed exploiting tracking detector information. The obtained measurements are in agreement with results reported in the literature and suggests the feasibility of range monitoring based on charged secondary particle detection: the implications for particle therapy monitoring applications are also discussed.
MeSH term(s)	Dose-Response Relationship, Radiation ; Heavy Ion Radiotherapy/adverse effects ; Helium/adverse effects ; Humans ; Polymethyl Methacrylate/radiation effects ; Radiation Monitoring/methods ; Radiotherapy Planning, Computer-Assisted/methods ; Scattering, Radiation
Chemical Substances	Helium (206GF3GB41) ; Polymethyl Methacrylate (9011-14-7)
Language	English
Publishing date	2018-03-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208857-5
ISSN	1361-6560 ; 0031-9155
ISSN (online)	1361-6560
ISSN	0031-9155
DOI	10.1088/1361-6560/aaa36a
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Article ; Online: Secondary radiation measurements for particle therapy applications: nuclear fragmentation produced by

Physics in medicine and biology

2017 Volume 62, Issue 4, Page(s) 1291–1309

Abstract: Nowadays there is a growing interest in particle therapy treatments exploiting light ion beams against tumors due to their enhanced relative biological effectiveness and high space selectivity. In particular promising results are obtained by the use ... ...

Abstract	Nowadays there is a growing interest in particle therapy treatments exploiting light ion beams against tumors due to their enhanced relative biological effectiveness and high space selectivity. In particular promising results are obtained by the use of
MeSH term(s)	Algorithms ; Helium/therapeutic use ; Humans ; Monte Carlo Method ; Phantoms, Imaging ; Polymethyl Methacrylate/chemistry ; Protons ; Radiation Monitoring/methods ; Radiotherapy Planning, Computer-Assisted ; Relative Biological Effectiveness ; Software
Chemical Substances	Protons ; Helium (206GF3GB41) ; Polymethyl Methacrylate (9011-14-7)
Language	English
Publishing date	2017-02-21
Publishing country	England
Document type	Journal Article
ZDB-ID	208857-5
ISSN	1361-6560 ; 0031-9155
ISSN (online)	1361-6560
ISSN	0031-9155
DOI	10.1088/1361-6560/aa5307
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Article ; Online: Secondary radiation measurements for particle therapy applications: prompt photons produced by

Physics in medicine and biology

2017 Volume 62, Issue 4, Page(s) 1438–1455

Abstract: Charged particle beams are used in particle therapy (PT) to treat oncological patients due to their selective dose deposition in tissues with respect to the photons and electrons used in conventional radiotherapy. Heavy (Z > 1) PT beams can ... ...

Abstract	Charged particle beams are used in particle therapy (PT) to treat oncological patients due to their selective dose deposition in tissues with respect to the photons and electrons used in conventional radiotherapy. Heavy (Z > 1) PT beams can additionally be exploited for their high biological effectiveness in killing cancer cells. Nowadays, protons and carbon ions are used in PT clinical routines. Recently, interest in the potential application of helium and oxygen beams has been growing. With respect to protons, such beams are characterized by their reduced multiple scattering inside the body, increased linear energy transfer, relative biological effectiveness and oxygen enhancement ratio. The precision of PT demands online dose monitoring techniques, crucial to improving the quality assurance of any treatment: possible patient mis-positioning and biological tissue changes with respect to the planning CT scan could negatively affect the outcome of the therapy. The beam range confined in the irradiated target can be monitored thanks to the neutral or charged secondary radiation emitted by the interactions of hadron beams with matter. Among these secondary products, prompt photons are produced by nuclear de-excitation processes, and at present, different dose monitoring and beam range verification techniques based on prompt-γ detection are being proposed. It is hence of importance to perform γ yield measurement in therapeutic-like conditions. In this paper we report on the yields of prompt photons produced by the interaction of helium, carbon and oxygen ion beams with a poly-methyl methacrylate (PMMA) beam stopping target. The measurements were performed at the Heidelberg Ion-Beam Therapy Center (HIT) with beams of different energies. An LYSO scintillator, placed at [Formula: see text] and [Formula: see text] with respect to the beam direction, was used as the photon detector. The obtained γ yields for the carbon ion beams are compared with results from the literature, while no other results from helium and oxygen beams have been published yet. A discussion on the expected resolution of a slit camera detector is presented, demonstrating the feasibility of a prompt-γ-based monitoring technique for PT treatments using helium, carbon and oxygen ion beams.
MeSH term(s)	Carbon/chemistry ; Carbon/therapeutic use ; Heavy Ion Radiotherapy/adverse effects ; Heavy Ion Radiotherapy/methods ; Heavy Ion Radiotherapy/standards ; Helium/chemistry ; Helium/therapeutic use ; Humans ; Linear Energy Transfer ; Photons ; Polymethyl Methacrylate/radiation effects ; Protons/therapeutic use ; Relative Biological Effectiveness ; Scintillation Counting/instrumentation ; Scintillation Counting/methods
Chemical Substances	Protons ; Helium (206GF3GB41) ; Carbon (7440-44-0) ; Polymethyl Methacrylate (9011-14-7)
Language	English
Publishing date	2017-02-21
Publishing country	England
Document type	Journal Article
ZDB-ID	208857-5
ISSN	1361-6560 ; 0031-9155
ISSN (online)	1361-6560
ISSN	0031-9155
DOI	10.1088/1361-6560/62/4/1438
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Book ; Online: Dependence of the energy resolution of a scintillating crystal on the readout integration time

Bocci, V. / Chao, D. / Chiodi, G. / Faccini, R. / Ferroni, F. / Lunadei, R. / Martellotti, G. / Penso, G. / Pinci, D. / Recchia, L.

2012

Abstract: The possibilty of performing high-rate calorimetry with a slow scintillator crystal is studied. In this experimental situation, to avoid pulse pile-up, it can be necessary to base the energy measurement on only a fraction of the emitted light, thus ... ...

Abstract	The possibilty of performing high-rate calorimetry with a slow scintillator crystal is studied. In this experimental situation, to avoid pulse pile-up, it can be necessary to base the energy measurement on only a fraction of the emitted light, thus spoiling the energy resolution. This effect was experimentally studied with a BGO crystal and a photomultiplier followed by an integrator, by measuring the peak amplitude of the signals. The experimental data show that the energy resolution is exclusively due to the statistical fluctuations of the number of photoelectrons contributing to the peak amplitude. When such number is small its fluctuations are even smaller than those predicted by Poisson statistics. These results were confirmed by a Monte Carlo simulation which allows to estimate, in a general case, the energy resolution, given the total number of photoelectrons, the scintillation time and the integration time.
Keywords	Physics - Instrumentation and Detectors ; High Energy Physics - Experiment
Subject code	612
Publishing date	2012-07-20
Publishing country	us
Document type	Book ; Online
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Article ; Online: Design of a new tracking device for on-line beam range monitor in carbon therapy.

Traini, Giacomo / Battistoni, Giuseppe / Bollella, Angela / Collamati, Francesco / De Lucia, Erika / Faccini, Riccardo / Ferroni, Fernando / Frallicciardi, Paola Maria / Mancini-Terracciano, Carlo / Marafini, Michela / Mattei, Ilaria / Miraglia, Federico / Muraro, Silvia / Paramatti, Riccardo / Piersanti, Luca / Pinci, Davide / Rucinski, Antoni / Russomando, Andrea / Sarti, Alessio /

Sciubba, Adalberto / Senzacqua, Martina / Solfaroli-Camillocci, Elena / Toppi, Marco / Voena, Cecilia / Patera, Vincenzo

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

2017 Volume 34, Page(s) 18–27

Abstract: Charged particle therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbon ions. A critical issue is the monitoring of the beam range so to check the correct dose deposition to the tumor and surrounding tissues. ... ...

Abstract	Charged particle therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbon ions. A critical issue is the monitoring of the beam range so to check the correct dose deposition to the tumor and surrounding tissues. The design of a new tracking device for beam range real-time monitoring in pencil beam carbon ion therapy is presented. The proposed device tracks secondary charged particles produced by beam interactions in the patient tissue and exploits the correlation of the charged particle emission profile with the spatial dose deposition and the Bragg peak position. The detector, currently under construction, uses the information provided by 12 layers of scintillating fibers followed by a plastic scintillator and a pixelated Lutetium Fine Silicate (LFS) crystal calorimeter. An algorithm to account and correct for emission profile distortion due to charged secondaries absorption inside the patient tissue is also proposed. Finally detector reconstruction efficiency for charged particle emission profile is evaluated using a Monte Carlo simulation considering a quasi-realistic case of a non-homogenous phantom.
MeSH term(s)	Equipment Design ; Heavy Ion Radiotherapy/instrumentation ; Phantoms, Imaging ; Protons ; Radiotherapy Dosage ; Scintillation Counting
Chemical Substances	Protons
Language	English
Publishing date	2017-02
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1122650-x
ISSN	1724-191X ; 1120-1797
ISSN (online)	1724-191X
ISSN	1120-1797
DOI	10.1016/j.ejmp.2017.01.004
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Article: Monitoring of Hadrontherapy Treatments by Means of Charged Particle Detection.

Muraro, Silvia / Battistoni, Giuseppe / Collamati, Francesco / De Lucia, Erika / Faccini, Riccardo / Ferroni, Fernando / Fiore, Salvatore / Frallicciardi, Paola / Marafini, Michela / Mattei, Ilaria / Morganti, Silvio / Paramatti, Riccardo / Piersanti, Luca / Pinci, Davide / Rucinski, Antoni / Russomando, Andrea / Sarti, Alessio / Sciubba, Adalberto / Solfaroli-Camillocci, Elena /

Toppi, Marco / Traini, Giacomo / Voena, Cecilia / Patera, Vincenzo

Frontiers in oncology

2016 Volume 6, Page(s) 177

Abstract: The interaction of the incoming beam radiation with the patient body in hadrontherapy treatments produces secondary charged and neutral particles, whose detection can be used for monitoring purposes and to perform an on-line check of beam particle range. ...

Abstract	The interaction of the incoming beam radiation with the patient body in hadrontherapy treatments produces secondary charged and neutral particles, whose detection can be used for monitoring purposes and to perform an on-line check of beam particle range. In the context of ion-therapy with active scanning, charged particles are potentially attractive since they can be easily tracked with a high efficiency, in presence of a relatively low background contamination. In order to verify the possibility of exploiting this approach for in-beam monitoring in ion-therapy, and to guide the design of specific detectors, both simulations and experimental tests are being performed with ion beams impinging on simple homogeneous tissue-like targets (PMMA). From these studies, a resolution of the order of few millimeters on the single track has been proven to be sufficient to exploit charged particle tracking for monitoring purposes, preserving the precision achievable on longitudinal shape. The results obtained so far show that the measurement of charged particles can be successfully implemented in a technology capable of monitoring both the dose profile and the position of the Bragg peak inside the target and finally lead to the design of a novel profile detector. Crucial aspects to be considered are the detector positioning, to be optimized in order to maximize the available statistics, and the capability of accounting for the multiple scattering interactions undergone by the charged fragments along their exit path from the patient body. The experimental results collected up to now are also valuable for the validation of Monte Carlo simulation software tools and their implementation in Treatment Planning Software packages.
Language	English
Publishing date	2016-08-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2016.00177
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Article ; Online: Toward radioguided surgery with β- decays: uptake of a somatostatin analogue, DOTATOC, in meningioma and high-grade glioma.

Collamati, Francesco / Pepe, Alessandra / Bellini, Fabio / Bocci, Valerio / Chiodi, Giacomo / Cremonesi, Marta / De Lucia, Erika / Ferrari, Mahila E / Frallicciardi, Paola M / Grana, Chiara M / Marafini, Michela / Mattei, Ilaria / Morganti, Silvio / Patera, Vincenzo / Piersanti, Luca / Recchia, Luigi / Russomando, Andrea / Sarti, Alessio / Sciubba, Adalberto /

Senzacqua, Martina / Solfaroli Camillocci, Elena / Voena, Cecilia / Pinci, Davide / Faccini, Riccardo

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

2014 Volume 56, Issue 1, Page(s) 3–8

Abstract: Unlabelled: A novel radioguided surgery (RGS) technique for cerebral tumors using β(-) radiation is being developed. Checking for a radiotracer that can deliver a β(-) emitter to the tumor is a fundamental step in the deployment of such a technique. ... ...

Abstract	Unlabelled: A novel radioguided surgery (RGS) technique for cerebral tumors using β(-) radiation is being developed. Checking for a radiotracer that can deliver a β(-) emitter to the tumor is a fundamental step in the deployment of such a technique. This paper reports a study of the uptake of (90)Y-DOTATOC in meningiomas and high-grade gliomas (HGGs) and a feasibility study of the RGS technique in these types of tumor. Estimates were performed assuming the use of a β(-) probe under development with a sensitive area 2.55 mm in radius to detect 0.1-mL residuals. Methods: Uptake and background from healthy tissues were estimated on (68)Ga-DOTATOC PET scans of 11 meningioma patients and 12 HGG patients. A dedicated statistical analysis of the DICOM images was developed and validated. The feasibility study was performed using full simulation of emission and detection of the radiation, accounting for the measured uptake and background rate. Results: All meningioma patients but one with an atypical extracranial tumor showed high uptake of DOTATOC. In terms of feasibility of the RGS technique, we estimated that by administering a 3 MBq/kg activity of radiotracer, the time needed to detect a 0.1-mL remnant with 5% false-negative and 1% false-positive rates is less than 1 s. Actually, to achieve a detection time of 1 s the required activities to administer were as low as 0.2-0.5 MBq/kg in many patients. In HGGs, the uptake was lower than in meningiomas, but the tumor-to-nontumor ratio was higher than 4, which implies that the tracer can still be effective for RGS. It was estimated that by administering 3 mBq/kg of radiotracer, the time needed to detect a 0.1-mL remnant is less than 6 s, with the exception of the only oligodendroma in the sample. Conclusion: Uptake of (90)Y-DOTATOC in meningiomas was high in all studied patients. Uptake in HGGs was significantly worse than in meningiomas but was still acceptable for RGS, particularly if further research and development are done to improve the performance of the β(-) probe.
MeSH term(s)	Beta Particles ; Biological Transport ; Glioma/metabolism ; Glioma/pathology ; Glioma/surgery ; Humans ; Meningeal Neoplasms/metabolism ; Meningeal Neoplasms/surgery ; Meningioma/metabolism ; Meningioma/surgery ; Neoplasm Grading ; Octreotide/analogs & derivatives ; Octreotide/chemistry ; Octreotide/metabolism ; Somatostatin/analogs & derivatives ; Surgery, Computer-Assisted/methods
Chemical Substances	Somatostatin (51110-01-1) ; 90Y-octreotide, DOTA-Tyr(3)- (ABF7OG3FA3) ; Octreotide (RWM8CCW8GP)
Language	English
Publishing date	2014-12-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80272-4
ISSN	1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
ISSN (online)	1535-5667
ISSN	0097-9058 ; 0161-5505 ; 0022-3123
DOI	10.2967/jnumed.114.145995
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Zs.A 114: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Book ; Online: An Intraoperative $\beta^-$ Detecting Probe For Radio-Guided Surgery in Tumour Resection

Russomando, Andrea / Bellini, Fabio / Bocci, Valerio / Chiodi, Giacomo / Collamati, Francesco / De Lucia, Erika / Donnarumma, Raffaella / Faccini, Riccardo / Terracciano, Carlo Mancini / Marafini, Michela / Paramatti, Riccardo / Patera, Vincenzo / Pinci, %Davide / Recchia, Luigi / Sarti, Alessio / Sciubba, Adalberto / Camillocci, Elena Solfaroli / Voena, Cecilia / Morganti, Silvio

2015

Abstract: The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the lesion, as for ...

Abstract	The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the lesion, as for brain tumours. Feasibility studies on meningioma, glioma, and neuroendocrine tumors already estimated the potentiality of this new treatment. To validate the technique, prototypes of the intraoperative probe required by the technique to detect $\beta^-$ radiation have been developed. This paper discusses the design details of the device and the tests performed in laboratory. In such tests particular care has to be taken to reproduce the surgical field conditions. The innovative technique to produce specific phantoms and the dedicated testing protocols is described in detail. Comment: 7 pages, 15 figures
Keywords	Physics - Medical Physics ; Physics - Instrumentation and Detectors
Subject code	616 ; 621
Publishing date	2015-11-06
Publishing country	us
Document type	Book ; Online
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Article ; Online: Measurement of CP Violation in B^{0}→ψ(→ℓ^{+}ℓ^{-})K_{S}^{0}(→π^{+}π^{-}) Decays.

Aaij, R / Abdelmotteleb, A S W / Abellan Beteta, C / Abudinén, F / Ackernley, T / Adeva, B / Adinolfi, M / Adlarson, P / Afsharnia, H / Agapopoulou, C / Aidala, C A / Ajaltouni, Z / Akar, S / Akiba, K / Albicocco, P / Albrecht, J / Alessio, F / Alexander, M / Alfonso Albero, A /

Aliouche, Z / Alvarez Cartelle, P / Amalric, R / Amato, S / Amey, J L / Amhis, Y / An, L / Anderlini, L / Andersson, M / Andreianov, A / Andreola, P / Andreotti, M / Andreou, D / Ao, D / Archilli, F / Artamonov, A / Artuso, M / Aslanides, E / Atzeni, M / Audurier, B / Bacher, D / Bachiller Perea, I / Bachmann, S / Bachmayer, M / Back, J J / Bailly-Reyre, A / Baladron Rodriguez, P / Balagura, V / Baldini, W / Baptista de Souza Leite, J / Barbetti, M / Barbosa, I R / Barlow, R J / Barsuk, S / Barter, W / Bartolini, M / Baryshnikov, F / Basels, J M / Bassi, G / Batsukh, B / Battig, A / Bay, A / Beck, A / Becker, M / Bedeschi, F / Bediaga, I B / Beiter, A / Belin, S / Bellee, V / Belous, K / Belov, I / Belyaev, I / Benane, G / Bencivenni, G / Ben-Haim, E / Berezhnoy, A / Bernet, R / Bernet Andres, S / Berninghoff, D / Bernstein, H C / Bertella, C / Bertolin, A / Betancourt, C / Betti, F / Bex, J / Bezshyiko, Ia / Bhom, J / Bian, L / Bieker, M S / Biesuz, N V / Billoir, P / Biolchini, A / Birch, M / Bishop, F C R / Bitadze, A / Bizzeti, A / Blago, M P / Blake, T / Blanc, F / Blank, J E / Blusk, S / Bobulska, D / Bocharnikov, V / Boelhauve, J A / Boente Garcia, O / Boettcher, T / Bohare, A / Boldyrev, A / Bolognani, C S / Bolzonella, R / Bondar, N / Borgato, F / Borghi, S / Borsato, M / Borsuk, J T / Bouchiba, S A / Bowcock, T J V / Boyer, A / Bozzi, C / Bradley, M J / Braun, S / Brea Rodriguez, A / Breer, N / Brodzicka, J / Brossa Gonzalo, A / Brown, J / Brundu, D / Buonaura, A / Buonincontri, L / Burke, A T / Burr, C / Bursche, A / Butkevich, A / Butter, J S / Buytaert, J / Byczynski, W / Cadeddu, S / Cai, H / Calabrese, R / Calefice, L / Cali, S / Calvi, M / Calvo Gomez, M / Cambon Bouzas, J / Campana, P / Campora Perez, D H / Campoverde Quezada, A F / Capelli, S / Capriotti, L / Carbone, A / Carcedo Salgado, L / Cardinale, R / Cardini, A / Carniti, P / Carus, L / Casais Vidal, A / Caspary, R / Casse, G / Cattaneo, M / Cavallero, G / Cavallini, V / Celani, S / 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Physical review letters

2024 Volume 132, Issue 2, Page(s) 21801

Abstract: A measurement of time-dependent CP violation in the decays of B^{0} and B[over ¯]^{0} mesons to the final states J/ψ(→μ^{+}μ^{-})K_{S}^{0}, ψ(2S)(→μ^{+}μ^{-})K_{S}^{0} and J/ψ(→e^{+}e^{-})K_{S}^{0} with K_{S}^{0}→π^{+}π^{-} is presented. The data ... ...

Abstract	A measurement of time-dependent CP violation in the decays of B^{0} and B[over ¯]^{0} mesons to the final states J/ψ(→μ^{+}μ^{-})K_{S}^{0}, ψ(2S)(→μ^{+}μ^{-})K_{S}^{0} and J/ψ(→e^{+}e^{-})K_{S}^{0} with K_{S}^{0}→π^{+}π^{-} is presented. The data correspond to an integrated luminosity of 6 fb^{-1} collected at a center-of-mass energy of sqrt[s]=13 TeV with the LHCb detector. The CP-violation parameters are measured to be S_{ψK_{S}^{0}}=0.717±0.013(stat)±0.008(syst) and C_{ψK_{S}^{0}}=0.008±0.012(stat)±0.003(syst). This measurement of S_{ψK_{S}^{0}} represents the most precise single measurement of the CKM angle β to date and is more precise than the current world average. In addition, measurements of the CP-violation parameters of the individual channels are reported and a combination with the LHCb Run 1 measurements is performed.
Language	English
Publishing date	2024-01-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.021801
Database	MEDical Literature Analysis and Retrieval System OnLINE

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