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Article ; Online: One-Step Treatment for Upgrading Bleached Bamboo Pulp to Dissolving Pulp High Solvency in Green Alkali/Urea Aqueous Solution

Jiao-Ping Shang / Pin Liang / Yun Peng / Ding-Feng Xu / Yi-Bao Li

Polymers, Vol 15, Iss 1475, p

2023 Volume 1475

Abstract: Bleached bamboo pulp, as a kind of natural cellulose, has received significant attention in the field of biomass materials due to its advantages of environmental protection and the abundance of raw materials. Low-temperature alkali/urea aqueous system is ...

Abstract	Bleached bamboo pulp, as a kind of natural cellulose, has received significant attention in the field of biomass materials due to its advantages of environmental protection and the abundance of raw materials. Low-temperature alkali/urea aqueous system is a green dissolution technology for cellulose, which has promising application prospects in the field of regenerated cellulose materials. However, bleached bamboo pulp, with high viscosity average molecular weight ( M η) and high crystallinity, is difficult to dissolve in an alkaline urea solvent system, restraining its practical application in the textile field. Herein, based on commercial bleached bamboo pulp with high M η, a series of dissolvable bamboo pulps with suitable M η was prepared using a method of adjusting the ratio of sodium hydroxide and hydrogen peroxide in the pulping process. Due to the hydroxyl radicals being able to react with hydroxyls of cellulose, molecular chains are cut down. Moreover, several regenerated cellulose hydrogels and films were fabricated in an ethanol coagulation bath or a citric acid coagulation bath, and the relationship between the properties of the regenerated materials and the M η of the bamboo cellulose was systematically studied. The results showed that hydrogel/film had good mechanical properties, as the M η is 8.3 × 10 4 and the tensile strength of a regenerated film and the film have values up to 101 MPa and 3.19 MPa, respectively. In this contribution, a simple method of a one-step oxidation of hydroxyl radicals to prepare bamboo cellulose with diversified M η is presented, providing an avenue for a preparation of dissolving pulp with different M η in an alkali/urea dissolution system and expanding the practical applications of bamboo pulp in biomass-based materials, textiles, and biomedical materials.
Keywords	bamboo pulp ; molecular weight ; one-step method ; high solvency ; Organic chemistry ; QD241-441
Subject code	660
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Case report: A case of acute mastitis associated with reactive cutaneous capillary endothelial proliferation after camrelizumab treatment: A new immune-related adverse event.

Wu, Ping-Shang / Xiong, Dan / Feng, Yang-Bo / Xiang, Luan / Zhu, Jian

Frontiers in immunology

2022 Volume 13, Page(s) 939873

Abstract: Lung cancer is a malignant tumor with the highest morbidity and mortality rate worldwide, and it seriously endangers human health. In recent years, immunotherapy has been widely used in lung cancer and has achieved great benefits, especially the ... ...

Abstract	Lung cancer is a malignant tumor with the highest morbidity and mortality rate worldwide, and it seriously endangers human health. In recent years, immunotherapy has been widely used in lung cancer and has achieved great benefits, especially the application of promoting antitumor immune defense. However, immune-related adverse events (irAEs) caused by immune checkpoint inhibitors have received increasing attention, which largely limits their use. We report the first case of new acute mastitis caused by anti-PD1 inhibitors due to lung adenocarcinoma. A 65-year-old female patient came to our hospital for treatment with cough and shortness of breath for one month. Chest CT showed that the malignant tumor in the lower lobe of the right lung with pleural effusion had metastasized to many places, and then pleural effusion was taken for pathological examination. Pathological examination indicated that the pleural fluid originated from lung adenocarcinoma. Subsequently, the patient received platinum-containing dual-agent chemotherapy (carboplatin and pemetrexed disodium) combined with immunotherapy (camrelizumab). During treatment, the patient developed known adverse events and unreported acute mastitis. After stopping camrelizumab, the patient's mastitis gradually improved. Our case shows that acute mastitis might be a new adverse event after the use of camrelizumab. Since this new adverse event has not been reported, we hope that oncology medical workers can obtain insight from our case and use it as a reference for the identification and management of irAEs.
MeSH term(s)	Adenocarcinoma of Lung/drug therapy ; Aged ; Antibodies, Monoclonal, Humanized ; Cell Proliferation ; Female ; Humans ; Lung Neoplasms/complications ; Lung Neoplasms/drug therapy ; Mastitis ; Pleural Effusion
Chemical Substances	Antibodies, Monoclonal, Humanized ; camrelizumab (73096E137E)
Language	English
Publishing date	2022-08-25
Publishing country	Switzerland
Document type	Case Reports ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2022.939873
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Article: Case Report: Upper limb dysfunction may be caused by chest wall mass excision: An enlightenment from a special case.

Wu, Ping-Shang / Yuan, Ling / Xiong, Dan / Gao, Yan-Hong / Xiang, Luan

Frontiers in oncology

2022 Volume 12, Page(s) 947055

Abstract: Of all the thoracic surgical procedures, chest wall surgery is probably the lowest-risk type. In fact, it is not so. Clinical work also often has the trap of chest wall surgery. An operation to remove a mass in the axilla may result in upper limb ... ...

Abstract	Of all the thoracic surgical procedures, chest wall surgery is probably the lowest-risk type. In fact, it is not so. Clinical work also often has the trap of chest wall surgery. An operation to remove a mass in the axilla may result in upper limb disability on the affected side. Here, we report the case of a 47-year-old female patient with a left chest wall adjacent axillary mass, which was considered an abnormal structural lymph node on color ultrasound examination and chest CT. Otherwise, she felt no discomfort. The left upper limb moved freely without being affected by the mass. A routine resection of the tumor was performed after the preoperative examination was completed. After the operation, the incision recovered well. However, the day after the surgery, she developed numbness and pain in her left little finger and ring finger, pain that often kept her from sleeping. The mass was confirmed to be a schwannoma with cystic degeneration by pathology slicing after the operation. By this time, doctors were alerted to the fact that the removal of the chest wall mass had nearly disabled the left upper limb of the patient, which was a great warning to the thoracic surgeon. In this case report, we hope that all surgeons will be cautious and careful and will not trust the imaging diagnosis too much. It is also hoped that the patient understands that some procedures may lead to unexpected complications.
Language	English
Publishing date	2022-08-03
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2022.947055
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Article ; Online: Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-α-driven inflammation and ER stressResearch in context

Deheng Chen / Di Lu / Haixiao Liu / Enxing Xue / Yu Zhang / Ping Shang / Xiaoyun Pan

EBioMedicine, Vol 50, Iss , Pp 395-

2019 Volume 407

Abstract: Background: Epigenetic mechanisms have been reported to play key roles in osteoarthritis (OA) development. P300/CBP-associated factor (PCAF) is a member of the histone acetyltransferases, which exhibits a strong relationship with endoplasmic reticulum ( ... ...

Abstract	Background: Epigenetic mechanisms have been reported to play key roles in osteoarthritis (OA) development. P300/CBP-associated factor (PCAF) is a member of the histone acetyltransferases, which exhibits a strong relationship with endoplasmic reticulum (ER) stress and transcription factor nuclear factor kappa B (NF-κB) signals. Salidroside, a natural histone acetylation inhibitor, showed its anti-inflammatory and anti-apoptotic effects in lipopolysaccharide (LPS)-stimulated microglia cells in our previous study. However, whether Sal has a protective effect against OA remains unknown, and its relationships to PCAF, NF-κB, and the ER stress pathway should be explored further. Methods: We identified the role of PCAF in the pathogenesis of OA and determined the chondroprotective effect of Sal on both tumor necrosis factor alpha (TNF-α)-treated human chondrocytes and a destabilized medial meniscus (DMM) mouse OA model. Findings: We found increased PCAF expression in human OA cartilage and TNF-α-driven chondrocytes. Meanwhile, silencing of PCAF attenuated nuclear p65 and C/EBP homologous protein levels in chondrocytes upon TNF-α stimulation. Furthermore, Sal was found to specifically bind to the inhibitory site of the PCAF protein structure, which subsequently reversed the TNF-α-induced activation of NF-κB signal and ER stress-related apoptosis in chondrocytes. In addition, the protective effect of Sal and its inhibitory effects on PCAF as well as inflammatory- and ER stress-related markers were also observed in the mouse DMM model. Interpretation: Pharmacological blockade of PCAF by Sal ameliorates OA development via inhibition of inflammation and ER stress, which makes Sal a promising therapeutic agents for the treatment of OA. Keywords: PCAF, Salidroside, Osteoarthritis, NF-κB, ER stress
Keywords	Medicine ; R ; Medicine (General) ; R5-920
Subject code	616
Language	English
Publishing date	2019-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: Overexpression of Soybean GmWRI1a Stably Increases the Seed Oil Content in Soybean

Zhikun Wang / Yuanzhuo Wang / Ping Shang / Chao Yang / Mingming Yang / Jinxiu Huang / Baizheng Ren / Zhaohui Zuo / Qingyan Zhang / Wenbin Li / Bo Song

International Journal of Molecular Sciences, Vol 23, Iss 5084, p

2022 Volume 5084

Abstract: WRINKLED1 (WRI1), an APETALA2/ethylene-responsive-element-binding protein (AP2/EREBP) subfamily transcription factor, plays a crucial role in the transcriptional regulation of plant fatty acid biosynthesis. In this study, GmWRI1a was overexpressed in the ...

Abstract	WRINKLED1 (WRI1), an APETALA2/ethylene-responsive-element-binding protein (AP2/EREBP) subfamily transcription factor, plays a crucial role in the transcriptional regulation of plant fatty acid biosynthesis. In this study, GmWRI1a was overexpressed in the soybean cultivar ‘Dongnong 50’ using Agrobacterium -mediated transformation to generate three transgenic lines with high seed oil contents. PCR and Southern blotting analysis showed that the T-DNA was inserted into the genome at precise insertion sites and was stably inherited by the progeny. Expression analysis using qRT-PCR and Western blotting indicated that GmWRI1a and bar driven by the CaMV 35S promoter were significantly upregulated in the transgenic plants at different developmental stages. Transcriptome sequencing results showed there were obvious differences in gene expression between transgenic line and transgenic receptor during seed developmental stages. KEGG analysis found that the differentially expressed genes mainly annotated to metabolic pathways, such as carbohydrated metabolism and lipid metabolism. A 2-year single-location field trial revealed that three transgenic lines overexpressing GmWRI1a (GmWRI1a-OE) showed a stable increase in seed oil content of 4.97–10.35%. Importantly, no significant effect on protein content and yield was observed. Overexpression of GmWRI1a changed the fatty acid composition by increasing the linoleic acid (C18:2) content and decreasing the palmitic acid (C16:0) content in the seed. The three GmWRI1a-OE lines showed no significant changes in agronomic traits. The results demonstrated that the three GmWRI1a overexpression lines exhibited consistent increases in seed oil content compared with that of the wild type and did not significantly affect the seed yield and agronomic traits. The genetic engineering of GmWRI1a will be an effective strategy for the improvement of seed oil content and value in soybean.
Keywords	soybean ; GmWRI1a ; overexpression ; oil content ; fatty acid composition ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: An amended species, Nilssoniopteris neimenguensis nom. nov., from the Lower Jurassic of the Xilinhot Basin, Inner Mongolia, northern China, with a reexamination of Nilssoniopteris species

Zhao, Yi / Ping Shang / Shenghui Deng / Xunlian Wang / Yuanzheng Lu

Review of palaeobotany and palynology. 2018 Aug., v. 255

2018

Abstract: An amended species, Nilssoniopteris neimenguensis (Wang, 1984) Zhao et Deng, nom. nov., is described from the Lower Jurassic Hongqi Formation of the Xilinhot Basin, Inner Mongolia, northern China, based on leaf macromorphology and cuticular structures. ... ...

Abstract	An amended species, Nilssoniopteris neimenguensis (Wang, 1984) Zhao et Deng, nom. nov., is described from the Lower Jurassic Hongqi Formation of the Xilinhot Basin, Inner Mongolia, northern China, based on leaf macromorphology and cuticular structures. Following a reexamination of the specimens published in the previous literature, a total of 86 species of Nilssoniopteris are recognized, and their stratigraphic and geographic distributions are analyzed. Nilssoniopteris first occurs in the Carnian of the Late Triassic of Central Europe and the southwest region of the United States. This genus spreads in the Euro-Sinian region in the Late Triassic and then gradually extends to the Siberian-Canadian region in the Early to Middle Jurassic, where it first experiences diversification and distribution expansion. After a decline in both diversity and geographic range in the Late Jurassic, Nilssoniopteris species flourish and almost completely migrate to the Siberian-Canadian region during the Early Cretaceous, and the genus finally dies out in the Cenomanian of the Late Cretaceous. The paleoclimatic conditions of Nilssoniopteris also experience a change from the subtropical-tropical zone to the warm temperate zone, indicating that the species may have grown in the warm humid temperate and subtropical-tropical zones with a general preference for warm, humid climates.
Keywords	basins ; Early Cretaceous epoch ; geographical distribution ; humid zones ; Late Cretaceous epoch ; Late Jurassic epoch ; leaves ; Middle Jurassic epoch ; temperate zones ; Triassic period ; Central European region ; China ; United States
Language	English
Dates of publication	2018-08
Size	p. 22-34.
Publishing place	Elsevier B.V.
Document type	Article
ISSN	0034-6667
DOI	10.1016/j.revpalbo.2018.04.013
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Synthesis, structure and photocatalytic property of a novel Zn(II) coordination polymer based on in situ synthetized pyridine-3,4-dicarboxylhydrazidate ligand.

Jin, Juan / Li, Han-Shu / Yan, Wen-Fu / Wang, Yu-Chang / Qiao, Qing-An / Zhang, Qin-Jun / Wu, Shu-Yue / Lu, Yuan-Hong / Ping, Shang-Fan / Jiang, Zheng-Yan

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

2020 Volume 233, Page(s) 118232

Abstract: One new pyridine-3,4-dicarboxylhydrazidate-coordinated compound [Zn(pdh)] 1 (pdh = pyridine-3,4-dicarboxylhydrazidate) was obtained under the hydrothermal conditions. Noteworthily, the pdh molecules in the title compound originated from the ligand in ... ...

Abstract	One new pyridine-3,4-dicarboxylhydrazidate-coordinated compound [Zn(pdh)] 1 (pdh = pyridine-3,4-dicarboxylhydrazidate) was obtained under the hydrothermal conditions. Noteworthily, the pdh molecules in the title compound originated from the ligand in situ reaction between organic pyridine-3,4-dicarboxylic acid (pdca) and N
Language	English
Publishing date	2020-03-05
Publishing country	England
Document type	Journal Article
ZDB-ID	210413-1
ISSN	1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
ISSN (online)	1873-3557
ISSN	0370-8322 ; 0584-8539 ; 1386-1425
DOI	10.1016/j.saa.2020.118232
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Article ; Online: Poly[[aquatris(μ3-hexamethylenetetramine-κ3N,N′,N′′)tris(p-toluenesulfonato-κO)trisilver(I)] trihydrate]

Hua Wu / Shao-Ping ShangGuan / Meng-Xiang Shang

Acta Crystallographica Section E, Vol 66, Iss 12, Pp m1665-m

2010 Volume 1666

Abstract: There are three AgI cations, three p-toluenesulfonate (pts) anions, three hexamethylenetetramine (hmt) molecules and four water molecules in the asymmetric unit of the title coordination polymer, {[Ag3(C7H7O3S)3(C6H12N4)3(H2O)]·3H2O}n. Two of the pts ... ...

Abstract	There are three AgI cations, three p-toluenesulfonate (pts) anions, three hexamethylenetetramine (hmt) molecules and four water molecules in the asymmetric unit of the title coordination polymer, {[Ag3(C7H7O3S)3(C6H12N4)3(H2O)]·3H2O}n. Two of the pts anions show positional disorder of their O atoms in 0.60:0.40 and 0.50:0.50 ratios. The AgI ion is coordinated by three hmt molecules in an approximate trigonal–planar AgN3 arrangement. In each case, longer Ag—O bonds to a water molecule and a pts anion complete a distorted trigonal–bipyramidal AgN3O2 geometry for the metal ion. In the crystal, the bridging hmt molecules and pts ions generate a wave-like layer parallel to (001) and O—H.O hydrogen-bonding interactions consolidate the packing.
Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2010-12-01T00:00:00Z
Publisher	International Union of Crystallography
Document type	Article ; Online
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Article ; Online: Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelet’s induced membrane in rats

Qian Tang / Haimin Jin / Minji Tong / Gang Zheng / Zhongjie Xie / Shangkun Tang / Jialei Jin / Ping Shang / Huazi Xu / Liyan Shen / Yu Zhang / Haixiao Liu

Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-

2018 Volume 15

Abstract: Bone grafts: improving chances of graft acceptance Repairs to serious bone injuries may be improved by blocking a signaling pathway that causes newly forming membranes to fail. Masquelet’s technique involves placing acrylic spacers in areas of bone ... ...

Abstract	Bone grafts: improving chances of graft acceptance Repairs to serious bone injuries may be improved by blocking a signaling pathway that causes newly forming membranes to fail. Masquelet’s technique involves placing acrylic spacers in areas of bone damage, inducing the formation of vascularised membranes which encourage the body to accept bone grafts. However, sometimes Masquelet’s membranes do not form correctly, leading to weaknesses in bone repairs and potential graft rejection. In experiments on rats, Qian Tang from Wenzhou Medical University, China, and coworkers found that a particular signaling pathway, D114/Notch1, was upregulated around 6 weeks post-operation, reducing blood vessel density and limiting new vessel growth, weakening the membranes. The team inhibited this pathway using an existing therapy that prevents blood clots. This treatment improved bone repairs by promoting the formation and function of blood vessels in membranes.
Keywords	Medicine ; R ; Biochemistry ; QD415-436
Language	English
Publishing date	2018-04-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Research data: (with research data) Tradeâoffs and evolution of thermal adaptation in the Irish potato famine pathogen Phytophthora infestans

Yang, LiâNa / Ce Yang / EâJiao Wu / Jeremy J. Burdon / Jiasui Zhan / LiâPing Jin / LiâPing Shang / Peter H. Thrall / Wen Zhu

Molecular ecology. 2016 Aug., v. 25, no. 16

2016

Abstract: Temperature is one of the most important environmental parameters with crucial impacts on nearly all biological processes. Due to anthropogenic activity, average air temperatures are expected to increase by a few degrees in coming decades, accompanied by ...

Abstract	Temperature is one of the most important environmental parameters with crucial impacts on nearly all biological processes. Due to anthropogenic activity, average air temperatures are expected to increase by a few degrees in coming decades, accompanied by an increased occurrence of extreme temperature events. Such global trends are likely to have various major impacts on human society through their influence on natural ecosystems, food production and biotic interactions, including diseases. In this study, we used a combination of statistical genetics, experimental evolution and common garden experiments to investigate the evolutionary potential for thermal adaptation in the potato late blight pathogen, Phytophthora infestans, and infer its likely response to changing temperatures. We found a tradeâoff associated with thermal adaptation to heterogeneous environments in P.Â infestans, with the degree of the tradeâoff peaking approximately at the pathogen's optimum growth temperature. A genetic tradeâoff in thermal adaptation was also evidenced by the negative association between a strain's growth rate and its thermal range for growth, and warm climates selecting for a low pathogen growth rate. We also found a mirror effect of phenotypic plasticity and genetic adaptation on growth rate. At below the optimum, phenotypic plasticity enhances pathogen's growth rate but nature selects for slower growing genotypes when temperature increases. At above the optimum, phenotypic plasticity reduces pathogen's growth rate but natural selection favours for faster growing genotypes when temperature increases further. We conclude from these findings that the growth rate of P.Â infestans will only be marginally affected by global warming.
Keywords	air temperature ; anthropogenic activities ; climate ; ecosystems ; environmental factors ; food production ; genotype ; global warming ; Irish potato famine ; natural selection ; pathogens ; phenotypic plasticity ; Phytophthora infestans
Language	English
Dates of publication	2016-08
Size	p. 4047-4058.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Research data
Note	JOURNAL ARTICLE
ZDB-ID	1126687-9
ISSN	1365-294X ; 0962-1083 ; 0962-1083
ISSN (online)	1365-294X
ISSN	0962-1083
DOI	10.1111/mec.13727
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