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  1. Article: On the Pictorial Art in Illustrating Microscopic Observations, with Original Drawings and Descriptions.

    Piper, R U

    The Chicago medical journal and examiner

    2023  Volume 34, Issue 3, Page(s) 193–200

    Language English
    Publishing date 2023-08-24
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Fellowship of the British Journal of Neurosurgery.

    Lammy, Simon / Piper, Rory / Mukerji, Nitin

    British journal of neurosurgery

    2023  Volume 37, Issue 2, Page(s) 125–126

    MeSH term(s) Humans ; Neurosurgery/education ; Fellowships and Scholarships ; Neurosurgical Procedures ; Internship and Residency
    Language English
    Publishing date 2023-02-03
    Publishing country England
    Document type Editorial
    ZDB-ID 639029-8
    ISSN 1360-046X ; 0268-8697
    ISSN (online) 1360-046X
    ISSN 0268-8697
    DOI 10.1080/02688697.2023.2173873
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    Zs.A 2210: Show issues Location:
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  3. Article ; Online: Offspring or phoronts? An alternative interpretation of the "kite-runner" fossil.

    Piper, Ross

    Proceedings of the National Academy of Sciences of the United States of America

    2016  Volume 113, Issue 24, Page(s) E3319

    MeSH term(s) Aircraft ; Fossils ; Humans ; Running
    Language English
    Publishing date 2016--14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1605909113
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    Zs.A 1148: Show issues Location:
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  4. Article ; Online: Silly season.

    Piper, R

    British dental journal

    2010  Volume 209, Issue 6, Page(s) 264–265

    MeSH term(s) Dentists ; European Union ; Humans ; Terminology as Topic ; United Kingdom
    Language English
    Publishing date 2010-09-25
    Publishing country England
    Document type Letter
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/sj.bdj.2010.826
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    Zs.MO 447: Show issues

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  5. Article ; Online: Reproductive-Toxicity-Related Endpoints in

    Camacho, Jessica A / Welch, Bonnie / Sprando, Robert L / Hunt, Piper R

    Journal of developmental biology

    2023  Volume 11, Issue 2

    Abstract: Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood. ...

    Abstract Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood.
    Language English
    Publishing date 2023-04-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720870-9
    ISSN 2221-3759 ; 2221-3759
    ISSN (online) 2221-3759
    ISSN 2221-3759
    DOI 10.3390/jdb11020018
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  6. Article ; Online: Reproductive-Toxicity-Related Endpoints in C. elegans Are Consistent with Reduced Concern for Dimethylarsinic Acid Exposure Relative to Inorganic Arsenic

    Jessica A. Camacho / Bonnie Welch / Robert L. Sprando / Piper R. Hunt

    Journal of Developmental Biology, Vol 11, Iss 18, p

    2023  Volume 18

    Abstract: Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood. Caenorhabditis elegans’ ( C. elegans ) transparent cuticle, along with the ... ...

    Abstract Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood. Caenorhabditis elegans’ ( C. elegans ) transparent cuticle, along with the conservation of key genetic pathways regulating developmental and reproductive toxicology (DART)-related processes such as germ stem cell renewal and differentiation, meiosis, and embryonic tissue differentiation and growth, support this model’s potential to address the need for quicker and more dependable testing methods for DART hazard identification. Organic and inorganic forms of mercury and arsenic had different effects on reproductive-related endpoints in C. elegans , with methylmercury (meHgCl) having effects at lower concentrations than mercury chloride (HgCl 2 ), and sodium arsenite (NaAsO 2 ) having effects at lower concentrations than dimethylarsinic acid (DMA). Progeny to adult ratio changes and germline apoptosis were seen at concentrations that also affected gravid adult gross morphology. For both forms of arsenic tested, germline histone regulation was altered at concentrations below those that affected progeny/adult ratios, while concentrations for these two endpoints were similar for the mercury compounds. These C. elegans findings are consistent with corresponding mammalian data, where available, suggesting that small animal model test systems may help to fill critical data gaps by contributing to weight of evidence assessments.
    Keywords reproductive-toxicity-related ; arsenic ; mercury ; organic ; inorganic ; C. elegans ; Biology (General) ; QH301-705.5
    Subject code 571
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Reproductive-Toxicity-Related Endpoints in C. elegans Are Consistent with Reduced Concern for Dimethylarsinic Acid Exposure Relative to Inorganic Arsenic

    Camacho, Jessica A. / Welch, Bonnie / Sprando, Robert L. / Hunt, Piper R.

    J Dev Biol. 2023 Apr. 26, v. 11, no. 2

    2023  

    Abstract: Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood. Caenorhabditis elegans’ (C. elegans) transparent cuticle, along with the ... ...

    Abstract Exposures to arsenic and mercury are known to pose significant threats to human health; however, the effects specific to organic vs. inorganic forms are not fully understood. Caenorhabditis elegans’ (C. elegans) transparent cuticle, along with the conservation of key genetic pathways regulating developmental and reproductive toxicology (DART)-related processes such as germ stem cell renewal and differentiation, meiosis, and embryonic tissue differentiation and growth, support this model’s potential to address the need for quicker and more dependable testing methods for DART hazard identification. Organic and inorganic forms of mercury and arsenic had different effects on reproductive-related endpoints in C. elegans, with methylmercury (meHgCl) having effects at lower concentrations than mercury chloride (HgCl₂), and sodium arsenite (NaAsO₂) having effects at lower concentrations than dimethylarsinic acid (DMA). Progeny to adult ratio changes and germline apoptosis were seen at concentrations that also affected gravid adult gross morphology. For both forms of arsenic tested, germline histone regulation was altered at concentrations below those that affected progeny/adult ratios, while concentrations for these two endpoints were similar for the mercury compounds. These C. elegans findings are consistent with corresponding mammalian data, where available, suggesting that small animal model test systems may help to fill critical data gaps by contributing to weight of evidence assessments.
    Keywords adults ; animal models ; apoptosis ; arsenic ; cacodylic acid ; germ cells ; hazard identification ; histones ; human health ; mammals ; meiosis ; mercuric chloride ; mercury ; methylmercury compounds ; progeny ; reproductive toxicology ; sodium arsenite ; stem cells ; weight-of-evidence
    Language English
    Dates of publication 2023-0426
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2720870-9
    ISSN 2221-3759
    ISSN 2221-3759
    DOI 10.3390/jdb11020018
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Designing a 3D Printed Model of the Skull-Base: A Collaboration Between Clinicians and Industry.

    Saleh, Youssuf / Piper, Rory / Richard, Michael / Jeyaretna, Sanjeeva / Cosker, Thomas

    Journal of medical education and curricular development

    2022  Volume 9, Page(s) 23821205221080703

    Abstract: Introduction: The role of three dimensional (3D) printing in neurosurgical education is becoming increasingly common. Notably, 3D printing can simulate complex anatomical pathways that may be difficult to regularly and accurately reproduce in cadavers. ... ...

    Abstract Introduction: The role of three dimensional (3D) printing in neurosurgical education is becoming increasingly common. Notably, 3D printing can simulate complex anatomical pathways that may be difficult to regularly and accurately reproduce in cadavers. One such example is the course of the facial nerve within the temporal bone and its relation to the labyrinth. This can aid pre-surgical planning and minimise surgical complications. Here we aim to develop a novel anatomically accurate model of the skull base which demonstrates key neuro vascular components and the course of the facial nerve within the temporal bone by developing a 3D printed model of the skull-base that can be used for medical education and pre-surgical planning.
    Materials and methods: We utilised a combination of Computed Tomography (CT) and angiography scans to reconstruct the skull base and its vascular contents. Neural components were digitally incorporated under the guidance of the Oxford neurosurgical team and the anatomy department. The model was integrated and printed using polymer jetting.
    Results: The model was successfully printed, with all neurovascular components included. Notably we were able to highlight the intra-temporal course of the facial nerve by creating a bony window within the temporal bone.
    Conclusion: Through a collaboration with industry and a multidisciplinary team, we were able to reproduce the base of the skull from patient neuro-imaging. Our model is both cost-effective, reproducible and can aid both medical students and neurosurgical trainees in their training/education.
    Language English
    Publishing date 2022-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2798123-X
    ISSN 2382-1205
    ISSN 2382-1205
    DOI 10.1177/23821205221080703
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  9. Article ; Online: Community Health Workers as Patient-Site Facilitators in Adult Hearing Aid Services via Synchronous Teleaudiology: Feasibility Results from the Conexiones Randomized Controlled Trial.

    Coco, Laura / Carvajal, Scott / Navarro, Cecilia / Piper, Rosie / Marrone, Nicole

    Ear and hearing

    2022  Volume 44, Issue 1, Page(s) 28–42

    Abstract: Objectives: The purpose of this study was to investigate the feasibility of Community Health Workers (CHWs) as patient-site facilitators in teleaudiology-facilitated hearing aid services to improve hearing aid rehabilitation outcomes for older Hispanic/ ... ...

    Abstract Objectives: The purpose of this study was to investigate the feasibility of Community Health Workers (CHWs) as patient-site facilitators in teleaudiology-facilitated hearing aid services to improve hearing aid rehabilitation outcomes for older Hispanic/Latino adults in a medically underserved, rural, US-Mexico border community.
    Design: A total of 28 adults (aged 55 to 89) with bilateral hearing loss participated in this study. Individuals were randomized to one of two teleaudiology intervention arms that differed at the level of the patient-site facilitator. Participants in the experimental group were assisted locally by trained CHW facilitators. Participants in the control group were assisted locally by trained university student facilitators. Synchronous (real-time) teleaudiology hearing aid services took place with participants located at a rural community health center and the clinician located a university 70 miles away. The results of this feasibility study are presented within the reach, effectiveness, adoption, implementation fidelity, and maintenance implementation framework.
    Results: Regarding reach, the participants in this study population are historically under-represented in research (primarily low-income Hispanic/Latino older adults). A total of 57 individuals were recruited, 47 were consented and assessed for eligibility and 28 individuals met inclusion criteria and were randomized. The average age of participants was 73.9 years, (range: 55 to 89 years) and most individuals were female (75%). Most participants (86%) reported having incomes less than $20,000 annually. Effectiveness results (via the Self Efficacy for Situational Communication Management Questionnaire) showed that both groups (CHW and control) significantly improved listening self-efficacy from pre-fitting baseline and no difference between groups was observed. Regarding datalogging, at the short-term follow-up, participants in the CHW group wore their hearing aids for more hours/day on average compared with participants in the control group. Implementation fidelity was high for both groups. Long-term maintenance of CHW-supported teleaudiology appears feasible given that training and institutional support is in place.
    Conclusions: Teleaudiology-delivered hearing aid services were feasible when facilitated locally by trained CHWs. Future efficacy and effectiveness research is warranted with CHWs and teleaudiology, potentially leading to a significant reduction in barriers for rural and medically under-resourced communities.
    MeSH term(s) Humans ; Female ; Aged ; Middle Aged ; Aged, 80 and over ; Male ; Hearing Aids ; Community Health Workers/education ; Feasibility Studies ; Treatment Outcome ; Auditory Perception
    Language English
    Publishing date 2022-10-18
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 603093-2
    ISSN 1538-4667 ; 0196-0202
    ISSN (online) 1538-4667
    ISSN 0196-0202
    DOI 10.1097/AUD.0000000000001281
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    Zs.A 1548: Show issues Location:
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  10. Article ; Online: Fecal microbiota transplants modulate the gut microbiome of a two-toed sloth (Choloepus didactylus).

    Thacher, Piper R / Kendrick, Erin L / Maslanka, Michael / Muletz-Wolz, Carly R / Bornbusch, Sally L

    Zoo biology

    2023  Volume 42, Issue 3, Page(s) 453–458

    Abstract: The microbes inhabiting an animal's gastrointestinal tracts, collectively known as the gut microbiome, are vital to animal health and wellbeing. For animals experiencing gut distress or infection, modulation of the gut microbiome, for example, via fecal ... ...

    Abstract The microbes inhabiting an animal's gastrointestinal tracts, collectively known as the gut microbiome, are vital to animal health and wellbeing. For animals experiencing gut distress or infection, modulation of the gut microbiome, for example, via fecal microbiota transplant (FMT), provides a possible disease prevention and treatment method. The beneficial microbes present in the donor's transplanted feces can help combat pathogens, assist in digestion, and rebalance the recipient's microbiota. Investigating the efficacy of FMTs in animal health is a crucial step toward improving management strategies for species under human care. We present a case study of the use of FMTs in a two-toed sloth experiencing abnormally large, clumped, and frequent stools. We used 16 S rRNA amplicon sequencing of fecal samples to (a) compare the microbiomes of the FMT donor, a healthy, cohoused conspecific, and the FMT recipient and (b) assess the influence of multiple rounds of FMTs on the recipient's microbiome and stool consistency and frequency over time. In response to the FMTs, we found that the recipient's microbiome showed trends toward increased diversity, shifted community composition, and altered membership that more resembled the community of the donor. FMT treatment was also associated with marked, yet temporary, alleviation of the recipient's abnormal bowel movements, suggesting a broader impact on gut health. Our results provide valuable preliminary evidence that FMT treatments can augment the recipient's gut microbiome, with potential implications for animal health and management.
    MeSH term(s) Humans ; Animals ; Fecal Microbiota Transplantation/veterinary ; Fecal Microbiota Transplantation/methods ; Gastrointestinal Microbiome ; Sloths ; Animals, Zoo ; Feces
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1499116-0
    ISSN 1098-2361 ; 0733-3188
    ISSN (online) 1098-2361
    ISSN 0733-3188
    DOI 10.1002/zoo.21751
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