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  1. Article: Entérocolite infectieuse grave de l'adulte en réanimation. Severe infectious enterocolitis of the adult in the ICU

    Piton, Gaël

    Médecine intensive réanimation

    2022  Volume 31, Issue 3, Page(s) 227

    Language French
    Document type Article
    ZDB-ID 2870987-1
    ISSN 2496-6142
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4839: Show issues Location:
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  2. Article: Coma With Hyperammonemia in a Patient With Kwashiorkor.

    Vieille, Thibault / Feillet, Francois / Wiedemann, Arnaud / Winiszewski, Hadrien / Piton, Gael

    Gastroenterology research

    2023  Volume 16, Issue 4, Page(s) 244–248

    Abstract: We describe a case of coma-related hyperammonemia in a woman presenting with severe edematous malnutrition (Kwashiorkor-like), without underlying hepatic disease. Our main hypothesis is that the patient developed a functional urea cycle disorder, due to ... ...

    Abstract We describe a case of coma-related hyperammonemia in a woman presenting with severe edematous malnutrition (Kwashiorkor-like), without underlying hepatic disease. Our main hypothesis is that the patient developed a functional urea cycle disorder, due to the inability to synthesize N-acetylglutamate which is the activator of the first enzymes (carbamoyl phosphate synthetase) of urea cycle, in a context of severe deficiency of essential amino acids and of acetyl-CoA. Severe hyperammonemia is a medical emergency exposing to the risk of cerebral edema. Urgent treatment should interrupt protein intake, stimulate protein anabolism, and remove ammonia from the blood using renal replacement therapy and ammonia scavengers. Hyperammonemia should be searched in case of unexplained coma, even among patients without hepatic disorder, in particular among young patients. Hyperammonemia should also be searched among patients with severe protein-calorie malnutrition.
    Language English
    Publishing date 2023-08-26
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2475913-2
    ISSN 1918-2813 ; 1918-2805
    ISSN (online) 1918-2813
    ISSN 1918-2805
    DOI 10.14740/gr1634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Early hyperoxia and 28-day mortality in patients on venoarterial ECMO support for refractory cardiogenic shock: discussion about potential confounding factors.

    Winiszewski, Hadrien / Piton, Gael / Capellier, Gilles

    Critical care (London, England)

    2022  Volume 26, Issue 1, Page(s) 313

    MeSH term(s) Extracorporeal Membrane Oxygenation/mortality ; Humans ; Hyperoxia ; Propensity Score ; Retrospective Studies ; Shock, Cardiogenic/mortality ; Shock, Cardiogenic/therapy
    Language English
    Publishing date 2022-10-17
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-022-04181-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
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  4. Article ; Online: Increased blood lactate during enteral nutrition in the critically ill: associations and treatment options.

    Piton, Gaël / Reignier, Jean / Calame, Paul

    Current opinion in clinical nutrition and metabolic care

    2022  Volume 26, Issue 2, Page(s) 167–173

    Abstract: Purpose of review: To evaluate the significance of blood lactate increase during enteral nutrition in the critically ill, and to propose diagnostic and therapeutic strategies.: Recent findings: Acute mesenteric ischemia occurs in approximately 1% of ... ...

    Abstract Purpose of review: To evaluate the significance of blood lactate increase during enteral nutrition in the critically ill, and to propose diagnostic and therapeutic strategies.
    Recent findings: Acute mesenteric ischemia occurs in approximately 1% of critically ill patients treated with catecholamine. Recent literature suggests that enteral nutrition is a risk factor of acute mesenteric ischemia, in particular in case of low cardiac output, by a mechanism of nonocclusive mesenteric ischemia. The association of clinical, biological, and computed tomography imaging might help to evaluate the reversibility of acute mesenteric ischemia.
    Summary: As enteral nutrition induces an increased metabolic work of the gut, the inadequation between oxygen delivery and demand exposes the gut to a phenomenon of nonocclusive mesenteric ischemia. Before initiation of enteral nutrition,, and before each increase of the enteral nutrition dose, the risk factors of nonocclusive mesenteric ischemia should be searched in order to prevent it. While under enteral nutrition, increased lactate concentration while receiving enteral nutrition requires the urgent search for nonocclusive mesenteric ischemia, and the adaptation of enteral nutrition (reduction, stop, and/or switch to parenteral nutrition or tolerate early nutrient restriction). Early signs of nonocclusive mesenteric ischemia should be searched in order to allow for a rapid diagnosis, before development of irreversible transmural necrosis. After the diagnosis of acute mesenteric ischemia, improving the balance between oxygen demand and delivery to the gut, evaluating the reversibility of the gut ischemia, and performing urgent resection in case of irreversible transmural necrosis should be the main objectives. After the resolution of acute mesenteric ischemia, the benefit risk analysis of enteral nutrition reintroduction should be evaluated.
    MeSH term(s) Humans ; Enteral Nutrition/methods ; Mesenteric Ischemia ; Critical Illness/therapy ; Necrosis ; Lactates ; Oxygen
    Chemical Substances Lactates ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-12-23
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1460178-3
    ISSN 1473-6519 ; 1363-1950
    ISSN (online) 1473-6519
    ISSN 1363-1950
    DOI 10.1097/MCO.0000000000000898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5586: Show issues Location:
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  5. Article ; Online: Full enteral nutrition should be avoided among patients with high vasopressor dose and low flow state.

    Piton, Gaël / Le Gouge, Amélie / Reignier, Jean

    Intensive care medicine

    2022  Volume 48, Issue 6, Page(s) 783–784

    MeSH term(s) Critical Care ; Enteral Nutrition ; Humans ; Vasoconstrictor Agents/therapeutic use
    Chemical Substances Vasoconstrictor Agents
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06703-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1089: Show issues Location:
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  6. Article ; Online: Outcomes and predictors of delayed endoscopic biliary drainage for severe acute cholangitis due to choledocholithiasis in an intensive care unit.

    Hedjoudje, Abdellah / Cheurfa, Chérifa / Et Talby, Mohamed / Levy, Philippe / Prat, Frédéric / Piton, Gaël

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  Volume 55, Issue 6, Page(s) 763–770

    Abstract: Background: Acute cholangitis (AC) is an infection of the biliary tract secondary to biliary obstruction requiring biliary drainage through endoscopic retrograde cholangiopancreatography. This study aims to compare the outcome between the early and ... ...

    Abstract Background: Acute cholangitis (AC) is an infection of the biliary tract secondary to biliary obstruction requiring biliary drainage through endoscopic retrograde cholangiopancreatography. This study aims to compare the outcome between the early and delayed ERCP in patients with severe AC.
    Methods: Patient with severe AC due to choledocholithiasis admitted to intensive care unit were included. Early ERCP was defined was as ERCP performed within 24 h following hospital admission. Propensity-score matching was used to reduce the imbalance between groups. The primary outcome was 30-day mortality. Secondary outcomes included length of hospital and ICU stay, onset or persistent organ failure.
    Results: The delayed ERCP group had a higher mortality rate at 30 days (45,5 versus 13%, <0.001) and at 1 year (59,7% versus 15,6%, p <0.001). Delayed ERCP had also a higher rate of respiratory adverse events (54,5 versus 27,8%, p = 0,002), longer ICU (7.41 versus 4.61, p = 0,004) and hospital (11,88 versus 9,22, p = 0,042) length of stay. Predictors of delayed ERCP were cardiac arrythmias, liver disease, creatinine value and white blood cell count at baseline.
    Conclusions: Delays in ERCP for patients with severe AC appear to be associated with higher mortality rate and prolonged ICU and hospital stays.
    MeSH term(s) Humans ; Choledocholithiasis/complications ; Choledocholithiasis/surgery ; Cholangitis/complications ; Hospitalization ; Cholangiopancreatography, Endoscopic Retrograde ; Intensive Care Units ; Drainage/adverse effects ; Retrospective Studies ; Acute Disease
    Language English
    Publishing date 2023-02-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.01.158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1134: Show issues Location:
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  7. Article ; Online: Author's Reply: ``Delayed ERCP in the setting of severe acute cholangitis - How much delay is ``Delayed''?''.

    Hedjoudje, Abdellah / Cheurfa, Chérifa / Talby, Mohamed Et / Levy, Philippe / Prat, Frédéric / Piton, Gaël

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  Volume 55, Issue 8, Page(s) 1149

    MeSH term(s) Humans ; Cholangiopancreatography, Endoscopic Retrograde ; Length of Stay ; Treatment Outcome ; Cholangitis/etiology ; Acute Disease ; Retrospective Studies
    Language English
    Publishing date 2023-06-12
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1134: Show issues Location:
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  8. Article ; Online: Author Correction: Quantifying iodine concentration in the normal bowel wall using dual-energy CT: influence of patient and contrast characteristics.

    Nehnahi, Majida / Simon, Gabriel / Moinet, Romain / Piton, Gael / Camelin, Camille / Ronot, Maxime / Delabrousse, Éric / Calame, Paul

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6123

    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56763-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Extracorporeal Membrane Oxygenation Cannula-Related Infections: Possible Interaction Between Prevention and Diagnosis.

    Winiszewski, Hadrien / Boyadjian, Charles / Piton, Gaël

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2021  Volume 68, Issue 2, Page(s) e36

    MeSH term(s) Cannula/adverse effects ; Extracorporeal Membrane Oxygenation/adverse effects
    Language English
    Publishing date 2021-10-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000001600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to "Atherosclerosis is a risk factor of mortality in patients with non-occlusive mesenteric ischemia".

    Calame, Paul / Piton, Gael / Delabrousse, Eric

    European journal of radiology

    2021  Volume 142, Page(s) 109836

    Language English
    Publishing date 2021-06-29
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2021.109836
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