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Article ; Online: Characteristics and outcomes among lung transplant patients with respiratory syncytial virus infection.

Mahan, Luke D / Points, April / Mohanka, Manish R / Bollineni, Srinivas / Joerns, John / Kaza, Vaidehi / La Hoz, Ricardo M / Gao, Ang / Zhang, Song / Torres, Fernando / Banga, Amit

Transplant infectious disease : an official journal of the Transplantation Society

2021  Volume 23, Issue 4, Page(s) e13661

Abstract: Background: To describe characteristics and outcomes among lung transplantation (LT) patients with respiratory syncytial virus (RSV) infection and elucidate the predictors of 1-year survival after RSV infection.: Methods: This was a retrospective ... ...

Abstract Background: To describe characteristics and outcomes among lung transplantation (LT) patients with respiratory syncytial virus (RSV) infection and elucidate the predictors of 1-year survival after RSV infection.
Methods: This was a retrospective chart review study among LT patients with RSV infection between 2013 and 2018 (90 episodes among 87 patients; mean age 56.3 ± 13.1 years, M:F 52:35). A contemporaneous control group consisting of LT patients without RSV infection (n = 183) was included. One-year survival after the RSV infection was the primary endpoint.
Results: Median time from LT to RSV infection was 30 (1-155) months. Before RSV infection, the median decline in forced vital capacity (FVC) was 9.7 cc (-17.8 to 83 cc) or 0.29% (-1.4% to 4.6%) per month, while the forced expiratory volume (FEV
Conclusions: A majority of LT patients in the current cohort did not experience an alteration in the trajectory of FVC or FEV
MeSH term(s) Adult ; Aged ; Cohort Studies ; Humans ; Lung ; Lung Transplantation/adverse effects ; Middle Aged ; Respiratory Syncytial Virus Infections ; Retrospective Studies
Language English
Publishing date 2021-06-22
Publishing country Denmark
Document type Journal Article
ZDB-ID 1476094-0
ISSN 1399-3062 ; 1398-2273
ISSN (online) 1399-3062
ISSN 1398-2273
DOI 10.1111/tid.13661
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