Article ; Online: Characteristics and outcomes among lung transplant patients with respiratory syncytial virus infection.
Transplant infectious disease : an official journal of the Transplantation Society
2021 Volume 23, Issue 4, Page(s) e13661
Abstract: Background: To describe characteristics and outcomes among lung transplantation (LT) patients with respiratory syncytial virus (RSV) infection and elucidate the predictors of 1-year survival after RSV infection.: Methods: This was a retrospective ... ...
Abstract | Background: To describe characteristics and outcomes among lung transplantation (LT) patients with respiratory syncytial virus (RSV) infection and elucidate the predictors of 1-year survival after RSV infection. Methods: This was a retrospective chart review study among LT patients with RSV infection between 2013 and 2018 (90 episodes among 87 patients; mean age 56.3 ± 13.1 years, M:F 52:35). A contemporaneous control group consisting of LT patients without RSV infection (n = 183) was included. One-year survival after the RSV infection was the primary endpoint. Results: Median time from LT to RSV infection was 30 (1-155) months. Before RSV infection, the median decline in forced vital capacity (FVC) was 9.7 cc (-17.8 to 83 cc) or 0.29% (-1.4% to 4.6%) per month, while the forced expiratory volume (FEV Conclusions: A majority of LT patients in the current cohort did not experience an alteration in the trajectory of FVC or FEV |
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MeSH term(s) | Adult ; Aged ; Cohort Studies ; Humans ; Lung ; Lung Transplantation/adverse effects ; Middle Aged ; Respiratory Syncytial Virus Infections ; Retrospective Studies | |||||
Language | English | |||||
Publishing date | 2021-06-22 | |||||
Publishing country | Denmark | |||||
Document type | Journal Article | |||||
ZDB-ID | 1476094-0 | |||||
ISSN | 1399-3062 ; 1398-2273 | |||||
ISSN (online) | 1399-3062 | |||||
ISSN | 1398-2273 | |||||
DOI | 10.1111/tid.13661 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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