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Article ; Online: Frequency of idiopathic intracranial hypertension with ultrasound in patients with fibromyalgia: Relation with function, central sensitization, and neuropathic pain.

Ketenci, Sertaç / Uzuner, Bora / Durmuş, Dilek / Polat, Murat

International journal of rheumatic diseases

2024 Volume 27, Issue 2, Page(s) e15066

Abstract: Objective: The purpose of this study was to evaluate the prevalence of idiopathic intracranial hypertension (IIH) in fibromyalgia (FMS) patients by utilizing ultrasound to measure the optic nerve sheath diameter (ONSD), a marker of elevated intracranial ...

Abstract	Objective: The purpose of this study was to evaluate the prevalence of idiopathic intracranial hypertension (IIH) in fibromyalgia (FMS) patients by utilizing ultrasound to measure the optic nerve sheath diameter (ONSD), a marker of elevated intracranial pressure and also to investigate the relationship with function, fatigue, quality of life (QOL), central sensitization (CS) and neuropathic pain. Methods: The study encompassed 80 female FMS patients and 75 healthy controls. Ultrasound was employed to measure the average ONSD in both groups. Conditions potentially elevating intracranial pressure were ruled out following neurological assessments. Pain (via visual analog scale, VAS), function (revised Fibromyalgia Impact Questionnaire, r-FIQ), QOL (Short Form-36, SF-36), fatigue (fatigue severity scale, FACIT), CS (Central Sensitization Scale), and neuropathic pain (Douleur Neuropathique-4) were evaluated. Results: The average ONSD was significantly higher in the patient group than the control group. Patients with ONSD >5.5 mm consistent with IIH were categorized as Group 1 (n = 54, 67.5%), while those with a diameter of 5.5 mm and below-formed Group 2. VAS pain (p = .033) and FIQ-R scores (p = .033) were significantly higher in Group 1 than Group 2. Headache was found more common in Group 1. Conclusion: This study unveils a substantial occurrence (67.5%) of IIH in FMS patients, suggesting shared pathophysiological mechanisms contributing to symptoms like fatigue, headache, and cognitive dysfunction. Additionally, these findings implicate heightened functional impairment, CS, headache, and fatigue in FMS patients with IIH.
MeSH term(s)	Humans ; Female ; Pseudotumor Cerebri/diagnostic imaging ; Pseudotumor Cerebri/epidemiology ; Fibromyalgia/diagnostic imaging ; Fibromyalgia/epidemiology ; Quality of Life ; Central Nervous System Sensitization ; Neuralgia/diagnostic imaging ; Neuralgia/epidemiology ; Fatigue ; Headache
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2426924-4
ISSN	1756-185X ; 1756-1841
ISSN (online)	1756-185X
ISSN	1756-1841
DOI	10.1111/1756-185X.15066
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Article ; Online: İslâm Hukukunda Karantina Ahkamı

POLAT, Murat

Volume: 7, Issue: 1 88-111 ; 2148-4899 ; Pamukkale Üniversitesi İlahiyat Fakültesi Dergisi

2020

Abstract: Dünya yaratıldığından itibaren ilâhî nizam gereği birtakım hastalıkların canlıların peşini bırakmadığı herkesin mâlumudur. Geçmiş yüzyıllarda insanın aciz kaldığı endemik, epidemik ve pandemik salgın hastalıkların ve deprem, sel, kasırga, heyelan vb. ... ...

Abstract	Dünya yaratıldığından itibaren ilâhî nizam gereği birtakım hastalıkların canlıların peşini bırakmadığı herkesin mâlumudur. Geçmiş yüzyıllarda insanın aciz kaldığı endemik, epidemik ve pandemik salgın hastalıkların ve deprem, sel, kasırga, heyelan vb. olağanüstü afetler sebebiyle kısmî helaklerin yaşanması bu yargının en somut delilidir. COVİD-19 Yeni Koronavirüs salgın hastalığı ise çağımızda yaşanan en son canlı şahit mesabesindedir. Böylesine ciddi ve herkesi tehdit eden ölümcül salgın hastalıklara karşı İslâm dini sessiz kalmamış, her alanda olduğu gibi bu alanda da asırlar öncesinden aldığı tedbirler ve uyguladığı korunma yöntemleriyle insanlığa örnek olmuştur. Bu tedbirlerden birisi de hiç şüphesiz karantina uygulaması ve esnasında başvurulan birtakım koruyucu metotlardır. Hz. Peygamber ve sonraki dönemlerde salgın hastalıklara karşı takınılması gereken ilk tavrın koruyucu hekimlik, sonraki tavrın ise karantina uygulamak olduğu müşahede edildiğine göre İslâm'da karantina ahkâmının mevcut olduğu açıkça söylenebilir. O halde bu araştırma İslâm hukukundaki karantina uygulamasının hukukî boyutunu ve bu uygulama esnasında başvurulan bazı metotları ele almayı amaçlamaktadır.
Keywords	İslâm Hukuku,Karantina,Salgın Hastalıklar,Koronavirüs,Ahkâm ; covid19
Language	Turkish
Publishing date	2020-06-30T00:00:00Z
Publisher	Pamukkale Üniversitesi
Publishing country	tr
Document type	Article ; Online
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Article ; Online: Validity and reliability evidence for the scale of distance education satisfaction of medical students based on item response theory (IRT).

Toraman, Çetin / Karadağ, Engin / Polat, Murat

BMC medical education

2022 Volume 22, Issue 1, Page(s) 94

Abstract: Background: The objective of this study is to reveal on the basis of the item response theory (IRT) the validity and reliability evidence for the data obtained from the scale prepared to determine the satisfaction with distance education in students ... ...

Abstract	Background: The objective of this study is to reveal on the basis of the item response theory (IRT) the validity and reliability evidence for the data obtained from the scale prepared to determine the satisfaction with distance education in students studying in medical schools. Methods: This is a quantitative study exploring IRT and measurement invariance evidence in developing a scale. The scale whose IRT evidence was explored was the Distance Education Satisfaction Scale (DESS). The data were obtained from 1332 medical school students who were studying at various universities. The data were analysed using the confirmatory factor analysis (CFA), multidimensional and unidimensional IRT, and measurement invariance. Results: A 20-item construct with 3 sub-factors was found for DESS. This construct was unable to pass the iteration limit in the multidimensional IRT analysis. A unidimensional IRT was used assuming that the 3 sub-factors were locally independent. Conclusions: The least informative items were item 23, 24 and 25 in Factor 1, item 3 in Factor 2, and items 13 and 18 in Factor 3. The most informative items of DESS were those that had adaptive, useful expressions that had meaningful content and were able to provide educator support, which are the properties emphasized in the literature with respect to satisfaction with distance education. A measurement invariance test made based on gender revealed that DESS satisfied measurement invariance by meeting the compliance indexes required for configural, metric, scalar and strict invariance as recommended in the literature. The results showed that it is possible to make comparisons on the basis of gender using DESS.
Language	English
Publishing date	2022-02-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2044473-4
ISSN	1472-6920 ; 1472-6920
ISSN (online)	1472-6920
ISSN	1472-6920
DOI	10.1186/s12909-022-03153-9
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Article ; Online: Is radiological rotation measurement affected by the fracture pattern in pediatric supracondylar humeral fractures?

Şahbat, Yavuz / Baysal, Özgür / Ağırdil, Yücel / Polat, Murat / Büyüktopçu, Ömer / Shammadli, Ziya / Erol, Bülent / Akgülle, Ahmet Hamdi

Acta radiologica (Stockholm, Sweden : 1987)

2023 Volume 64, Issue 10, Page(s) 2748–2756

Abstract: Background: In supracondylar humerus fractures (SCHF), the most frequently used method to calculate rotation is the Gordon lateral rotation percentage (GLRP) defined by Gordon et al. However, this technique includes only typical fractures (49%-80% of ... ...

Abstract	Background: In supracondylar humerus fractures (SCHF), the most frequently used method to calculate rotation is the Gordon lateral rotation percentage (GLRP) defined by Gordon et al. However, this technique includes only typical fractures (49%-80% of all fractures) from the Johns Hopkins (J-H) fracture classification system. Purpose: The aim of the study was to investigate (1) is Gordon criteria useful for John Hopkins subgroups of supracondylar fractures and (2) is Gordon criteria affected by internal and external rotation. Material and methods: This study was designed using four pediatric left humerus bones obtained from the Sawbone© company. For each bone, an osteotomy was made to mimic each of the J-H coronal fracture patterns. The cut bones were placed in a wooden rotation apparatus. The GLRP measurements were taken by five blinded observers. Results: In the repeated measurements of the observers, <20° rotation typical and <30° medial oblique and lateral oblique fracture pattern were measured as within the limits of an acceptable amount of rotation according to the Gordon criteria. However, for high fracture pattern (HFP), ≤30° internal rotation and <60° external rotation were determined to be within the acceptable rotation criteria according to the Gordon criteria. Conclusions: All fracture patterns have different characteristics; however, based on the data of this study, the Gordon criteria can be used safely for typical, medial oblique, and lateral oblique fracture patterns but it is necessary to lower the acceptable rate of 50% for HFP.
MeSH term(s)	Humans ; Child ; Fracture Fixation, Internal/methods ; Humeral Fractures/diagnostic imaging ; Humeral Fractures/surgery ; Humerus ; Radiography ; Retrospective Studies
Language	English
Publishing date	2023-08-18
Publishing country	England
Document type	Journal Article
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/02841851231189881
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Article ; Online: Efficacy and Safety of Tranexamic Acid in Resection and Endoprosthetic Reconstruction of Distal Femoral Osteosarcomas in Children: A Retrospective Cohort Study.

Sofulu, Omer / Ozturk, Ozer / Polat, Murat / Buyuktopcu, Omer / Kesimer, Mehmet D / Erol, Bulent

Journal of pediatric orthopedics

2021 Volume 41, Issue 8, Page(s) e686–e691

Abstract: Background: This study aimed to investigate the effect of intravenous tranexamic acid (TXA) on blood loss and transfusion rates in children who underwent resection and endoprosthetic reconstruction of distal femoral osteosarcomas.: Methods: The ... ...

Abstract	Background: This study aimed to investigate the effect of intravenous tranexamic acid (TXA) on blood loss and transfusion rates in children who underwent resection and endoprosthetic reconstruction of distal femoral osteosarcomas. Methods: The medical records of 56 patients who underwent resection and endoprosthetic reconstruction for distal femoral osteosarcomas between 2017 and 2019 were retrospectively reviewed. Patients were divided into 2 groups: group 1 consisted of 25 patients (11 male and 14 female, mean age 15.2±3 y) who received preoperative 15 mg/kg intravenous TXA, and group 2 consisted of 31 control patients (18 male and 13 female, mean age 14.3±2.6 y) who did not receive TXA. The groups were compared based on their total blood loss, intraoperative blood loss, hidden blood loss, postoperative drain output, transfusion requirements, preoperative and postoperative hemoglobin (Hb) and hematocrit (Htc) difference, length of hospital stays, operative time, and complications. Results: The mean total blood loss was lower in intravenous TXA group (1247.5±300.9 mL) when compared with control group (1715.7±857.0 mL) (P=0.018). The mean intraoperative blood loss in intravenous TXA group (386±109 mL) was lower than that in control group (977.4±610.7 mL) (P<0.001). Postoperative drain output at 24 and 48 hours was 198.0±61.8 and 72.4±27.4 mL in intravenous TXA group, respectively, and was low compared with 268.4±118.2 and 117.1±67.8 mL in control group (P=0.028 and 0.006). The rate of patients requiring transfusion was significantly lower in intravenous TXA group (56%) than in control group (83.9%). Preoperative and postoperative 6, 24, and 72 hours Hb and Htc differences were significantly lower in intravenous TXA group [(-1.7±1.8 g/dL P<0.001; -2.0±1.5 g/dL P<0.001; -2.3±1.7 g/dL P<0.001, for Hb) (-5.7±4.6, P<0.001; -6.9±4.0, P<0.001; -9.6±9.1, P<0.001, for Htc)]. Intravenous TXA group had shorter hospital stay time in comparison to control group (P<0.001). The operative time was significantly longer in the control group (P<0.05). No increase in pulmonary embolism or venous thromboembolism rate was observed with intravenous TXA use. Conclusion: We conclude that administration of intravenous TXA reduces intraoperative and postoperative blood loss, transfusion rates, and hospital stay in resection and endoprosthetic reconstruction of the distal femoral osteosarcomas in children. Type of study: This was a retrospective comparative study. Level of evidence: Level III.
MeSH term(s)	Administration, Intravenous ; Adolescent ; Antifibrinolytic Agents ; Blood Loss, Surgical/prevention & control ; Child ; Female ; Humans ; Male ; Osteosarcoma/surgery ; Retrospective Studies ; Tranexamic Acid
Chemical Substances	Antifibrinolytic Agents ; Tranexamic Acid (6T84R30KC1)
Language	English
Publishing date	2021-05-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	604642-3
ISSN	1539-2570 ; 0271-6798
ISSN (online)	1539-2570
ISSN	0271-6798
DOI	10.1097/BPO.0000000000001900
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Article ; Online: Rivaroxaban induced spontaneous hemoperitoneum around terminal ileum and cecum clinically mimicking acute appendicitis in a young patient

Inanc, Ibrahim Halil / Kılıc, Saadet / Polat, Murat

Ķazaķstannyṇ Klinikalyķ Medicinasy, Vol 2, Iss 56, Pp 50-

First case report

2020 Volume 52

Keywords	Internal medicine ; RC31-1245 ; Specialties of internal medicine ; RC581-951
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	National Scientific Medical Center
Document type	Article ; Online
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Article: The use of platelet indices, plateletcrit, mean platelet volume and platelet distribution width in emergency non-traumatic abdominal surgery: a systematic review.

Budak, Yasemin Ustundag / Polat, Murat / Huysal, Kagan

Biochemia medica

2016 Volume 26, Issue 2, Page(s) 178–193

Abstract: Platelet indices (PI) -- plateletcrit, mean platelet volume (MPV) and platelet distribution width (PDW) -- are a group of derived platelet parameters obtained as a part of the automatic complete blood count. Emerging evidence suggests that PIs may have ... ...

Abstract	Platelet indices (PI) -- plateletcrit, mean platelet volume (MPV) and platelet distribution width (PDW) -- are a group of derived platelet parameters obtained as a part of the automatic complete blood count. Emerging evidence suggests that PIs may have diagnostic and prognostic value in certain diseases. This study aimed to summarize the current scientific knowledge on the potential role of PIs as a diagnostic and prognostic marker in patients having emergency, non-traumatic abdominal surgery. In December 2015, we searched Medline/PubMed, Scopus and Google Scholar to identify all articles on PIs. Overall, considerable evidence suggests that PIs are altered with acute appendicitis. Although the role of PI in the differential diagnosis of acute abdomen remains uncertain, low MPV might be useful in acute appendicitis and acute mesenteric ischemia, with high MPV predicting poor prognosis in acute mesenteric ischemia. The current lack of consistency and technical standards in studies involving PIs should be regarded as a serious limitation to comparing these studies. Further large, multicentre prospective studies concurrently collecting data from different ethnicities and genders are needed before they can be used in routine clinical practice.
MeSH term(s)	Appendicitis/blood ; Appendicitis/pathology ; Blood Cell Count ; Blood Platelets ; Cholecystitis, Acute/blood ; Cholecystitis, Acute/pathology ; Diagnosis, Differential ; Humans ; Mean Platelet Volume ; Mesenteric Ischemia/blood ; Mesenteric Ischemia/pathology
Language	English
Publishing date	2016-06-06
Publishing country	Croatia
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	1208725-7
ISSN	1846-7482 ; 1330-0962
ISSN (online)	1846-7482
ISSN	1330-0962
DOI	10.11613/BM.2016.020
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Article ; Online: A case report of breast and liver metastases of thyroid follicular carcinoma.

Tanriverdi, Ozgur / Avci, Azu / Yugunt, Ibrahim / Polat, Murat

Journal of cancer research and therapeutics

2015 Volume 11, Issue 3, Page(s) 652

Abstract: Papillary and follicular thyroid carcinomas (FTCs) have a slowly biological behavior. Most distant metastasis sites are lung and bones. Breast and liver metastasis from differentiated thyroid carcinomas is uncommon. To the best of our knowledge, in ... ...

Abstract	Papillary and follicular thyroid carcinomas (FTCs) have a slowly biological behavior. Most distant metastasis sites are lung and bones. Breast and liver metastasis from differentiated thyroid carcinomas is uncommon. To the best of our knowledge, in English literature follicular thyroid cancer that is metastasis to breast was only in two female cases and to liver was in five patients. Herein, we present a case in whose 68-year-old woman who had a history FTC metastasis to vertebrae and synchronously developed breast and liver metastases within 1 year after first diagnosis.
MeSH term(s)	Adenocarcinoma, Follicular/pathology ; Aged ; Breast Neoplasms/pathology ; Breast Neoplasms/secondary ; Female ; Humans ; Liver Neoplasms/pathology ; Liver Neoplasms/secondary ; Neoplasm Metastasis ; Spine/pathology
Language	English
Publishing date	2015-07
Publishing country	India
Document type	Case Reports ; Letter
ZDB-ID	2187633-2
ISSN	1998-4138 ; 0973-1482
ISSN (online)	1998-4138
ISSN	0973-1482
DOI	10.4103/0973-1482.138003
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Article ; Online: Which Ischemic Stroke Subtype Is Associated with Hyperhomocysteinemia?

Gungor, Levent / Polat, Murat / Ozberk, Mehlika Berra / Avci, Bahattin / Abur, Ummet

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

2018 Volume 27, Issue 7, Page(s) 1921–1929

Abstract: Background: Stroke is still a major global health problem in both developed and developing countries. Defining stroke subtype and underlying etiologies is a major step to choose the best method for prophylaxis. Homocysteine is an endothelial toxin and ... ...

Abstract	Background: Stroke is still a major global health problem in both developed and developing countries. Defining stroke subtype and underlying etiologies is a major step to choose the best method for prophylaxis. Homocysteine is an endothelial toxin and elevated levels have been associated with stroke risk. In this study, we hypothesized that serum total homocysteine level may be related with specific atherothrombotic ischemic stroke subtypes and aimed to find if high serum homocysteine levels are correlated with any specific ischemic stroke subtype. Methods: Patients with ischemic stroke and aged between 18 and 65 are included. Ischemic stroke subtype is defined according to Causative Classification System. Hospital records are examined retrospectively to define patient demographics, ischemic stroke subtype, vascular risk factors, serum homocysteine, B12, and folic acid levels. Results: A total of 262 patients were included. Serum homocysteine level was elevated (≥16 µmol/L) in 99 patients (37.79%). The rate of patients with hyperhomocysteinemia was significantly more common in strokes due to intracranial stenosis (72.41%) (odds ratio 8.138; 95% confidence interval 2.366-27.989; P < .01) than extracranial large artery stenosis (52.00%), craniocervical arterial dissections (35.71%), cardioembolic strokes (27.87%), and lacunar infarctions (25.00%) after adjustment for other risk factors. High homocysteine levels were significantly more common in men and smokers (P < .05). Conclusions: Elevated levels of serum homocysteine are correlated with ischemic strokes due to intracranial large artery stenosis in young and middle-aged patients. This association may have an implication in stroke prophylaxis for intracranial atherosclerosis by using homocysteine-lowering therapies.
MeSH term(s)	Adult ; Biomarkers/blood ; Brain Ischemia/blood ; Brain Ischemia/classification ; Brain Ischemia/complications ; Female ; Homocysteine/blood ; Humans ; Hyperhomocysteinemia/blood ; Hyperhomocysteinemia/complications ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Stroke/blood ; Stroke/classification ; Stroke/complications
Chemical Substances	Biomarkers ; Homocysteine (0LVT1QZ0BA)
Language	English
Publishing date	2018-04-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1131675-5
ISSN	1532-8511 ; 1052-3057
ISSN (online)	1532-8511
ISSN	1052-3057
DOI	10.1016/j.jstrokecerebrovasdis.2018.02.033
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Article ; Online: Use of a blood gas analyzer and a laboratory autoanalyzer in routine practice to measure electrolytes in intensive care unit patients

Budak Yasemin U / Huysal Kagan / Polat Murat

BMC Anesthesiology, Vol 12, Iss 1, p

2012 Volume 17

Abstract: Abstract Background Electrolyte values are measured in most critically ill intensive care unit (ICU) patients using both an arterial blood gas analyzer (ABG) and a central laboratory auto-analyzer (AA). The aim of the present study was to investigate ... ...

Abstract	Abstract Background Electrolyte values are measured in most critically ill intensive care unit (ICU) patients using both an arterial blood gas analyzer (ABG) and a central laboratory auto-analyzer (AA). The aim of the present study was to investigate whether electrolyte levels assessed using an ABG and an AA were equivalent; data on sodium and potassium ion concentrations were examined. Methods We retrospectively studied patients hospitalized in the ICU between July and August 2011. Of 1,105 test samples, we identified 84 instances of simultaneous sampling of arterial and venous blood, where both Na + and K + levels were measured using a pHOx Stat Profile Plus L blood gas analyzer (Nova Biomedical, Waltham MA, USA) and a Roche Modular P autoanalyzer (Roche Diagnostics, Mannheim, Germany). Statistical measures employed to compare the data included Spearman's correlation coefficients, paired Student’s t -tests, Deming regression analysis, and Bland-Altman plots. Results The mean sodium concentration was 138.1 mmol/L (SD 10.2 mmol/L) using the ABG and 143.0 mmol/L (SD 10.5) using the AA (p < 0.001). The mean potassium level was 3.5 mmol/L (SD 0.9 mmol/L) using the ABG and 3.7 mmol/L (SD 1.0 mmol/L) using the AA (p < 0.001). The extent of inter-analyzer agreement was unacceptable for both K + and Na + , with biases of 0.150-0.352 and −0.97-10.05 respectively; the associated correlation coefficients were 0.88 and 0.90. Conclusions We conclude that the ABG and AA do not yield equivalent Na + and K + data. Concordance between ABG and AA should be established prior to introduction of new ABG systems.
Keywords	Surgery ; RD1-811 ; Medicine ; R ; DOAJ:Surgery ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Anesthesiology ; RD78.3-87.3
Subject code	333
Language	English
Publishing date	2012-08-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
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