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  1. Article ; Online: Critical Velocity, Maximal Lactate Steady State, and Muscle MCT1 and MCT4 after Exhaustive Running in Mice.

    Orsi, Juan B / Araujo, Lara S / Scariot, Pedro P M / Polisel, Emanuel E C / Cardoso, Luisa O / Gobatto, Claudio A / Manchado-Gobatto, Fúlvia B

    International journal of molecular sciences

    2023  Volume 24, Issue 21

    Abstract: Although the critical velocity (CV) protocol has been used to determine the aerobic capacity in rodents, there is a lack of studies that compare CV with maximal lactate steady state intensity (iMLSS) in mice. As a consequence, their physiological and ... ...

    Abstract Although the critical velocity (CV) protocol has been used to determine the aerobic capacity in rodents, there is a lack of studies that compare CV with maximal lactate steady state intensity (iMLSS) in mice. As a consequence, their physiological and molecular responses after exercise until exhaustion at CV intensity remain unclear. Thus, we aimed to compare and correlate CV with iMLSS in running mice, following different mathematical models for CV estimation. We also evaluated their physiological responses and muscle MCT1 and MCT4 after running until exhaustion at CV. Thirty C57BL/6J mice were divided into two groups (exercised-E and control-C). Group E was submitted to a CV protocol (4 days), using linear (
    MeSH term(s) Mice ; Animals ; Lactic Acid ; Mice, Inbred C57BL ; Muscle, Skeletal/physiology ; Symporters ; Liver ; Monocarboxylic Acid Transporters
    Chemical Substances Lactic Acid (33X04XA5AT) ; Symporters ; Monocarboxylic Acid Transporters
    Language English
    Publishing date 2023-10-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242115753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of high-intensity interval training in more or less active mice on biomechanical, biophysical and biochemical bone parameters.

    Polisel, Emanuel E C / Beck, Wladimir R / Scariot, Pedro P M / Pejon, Taciane M M / Gobatto, Claudio A / Manchado-Gobatto, Fúlvia B

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 6414

    Abstract: High-intensity interval training (HIIT) is of scientific interest due its role in improving physical fitness, but the effects of HIIT on bone health need be carefully explored. Further, it is necessary to know whether HIIT effects on bone health are ... ...

    Abstract High-intensity interval training (HIIT) is of scientific interest due its role in improving physical fitness, but the effects of HIIT on bone health need be carefully explored. Further, it is necessary to know whether HIIT effects on bone health are dependent on the physical activity levels. This may be experimentally tested since we have built a large cage (LC) that allows animals to move freely, promoting an increase of spontaneous physical activity (SPA) in comparison to a small cage (SC). Thus, we examined the effects of HIIT on biophysical, biomechanical and biochemical parameters of bone tissue of C57BL/6J mice living in cages of two different sizes: small (SC) or large (LC) cages with 1320 cm
    MeSH term(s) Animals ; Bone Density/physiology ; Calcium/analysis ; Femur/chemistry ; Femur/physiology ; High-Intensity Interval Training/adverse effects ; Housing, Animal ; Male ; Mice ; Mice, Inbred C57BL ; Phosphorus/analysis ; Physical Conditioning, Animal/physiology ; Physical Fitness/physiology ; Sedentary Behavior ; Weight-Bearing/physiology
    Chemical Substances Phosphorus (27YLU75U4W) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-03-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-85585-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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