Article ; Online: Critical Velocity, Maximal Lactate Steady State, and Muscle MCT1 and MCT4 after Exhaustive Running in Mice.
International journal of molecular sciences
2023 Volume 24, Issue 21
Abstract: Although the critical velocity (CV) protocol has been used to determine the aerobic capacity in rodents, there is a lack of studies that compare CV with maximal lactate steady state intensity (iMLSS) in mice. As a consequence, their physiological and ... ...
Abstract | Although the critical velocity (CV) protocol has been used to determine the aerobic capacity in rodents, there is a lack of studies that compare CV with maximal lactate steady state intensity (iMLSS) in mice. As a consequence, their physiological and molecular responses after exercise until exhaustion at CV intensity remain unclear. Thus, we aimed to compare and correlate CV with iMLSS in running mice, following different mathematical models for CV estimation. We also evaluated their physiological responses and muscle MCT1 and MCT4 after running until exhaustion at CV. Thirty C57BL/6J mice were divided into two groups (exercised-E and control-C). Group E was submitted to a CV protocol (4 days), using linear ( |
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MeSH term(s) | Mice ; Animals ; Lactic Acid ; Mice, Inbred C57BL ; Muscle, Skeletal/physiology ; Symporters ; Liver ; Monocarboxylic Acid Transporters |
Chemical Substances | Lactic Acid (33X04XA5AT) ; Symporters ; Monocarboxylic Acid Transporters |
Language | English |
Publishing date | 2023-10-30 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2019364-6 |
ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
ISSN (online) | 1422-0067 |
ISSN | 1422-0067 ; 1661-6596 |
DOI | 10.3390/ijms242115753 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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