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  1. Article ; Online: Fluorescence Guided Surgery-A New Era in Surgery.

    Chand, Manish / Polom, Karol

    Surgical innovation

    2022  Volume 29, Issue 4, Page(s) 477–478

    MeSH term(s) Fluorescence ; Optical Imaging ; Surgery, Computer-Assisted
    Language English
    Publishing date 2022-09-22
    Publishing country United States
    Document type Editorial
    ZDB-ID 2182571-3
    ISSN 1553-3514 ; 1553-3506
    ISSN (online) 1553-3514
    ISSN 1553-3506
    DOI 10.1177/15533506221128136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4269: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Current Trends and Beyond Conventional Approaches: Advancements in Breast Cancer Surgery through Three-Dimensional Imaging, Virtual Reality, Augmented Reality, and the Emerging Metaverse.

    Żydowicz, Weronika Magdalena / Skokowski, Jaroslaw / Marano, Luigi / Polom, Karol

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: Breast cancer stands as the most prevalent cancer globally, necessitating comprehensive care. A multidisciplinary approach proves crucial for precise diagnosis and treatment, ultimately leading to effective disease management. While surgical ... ...

    Abstract Breast cancer stands as the most prevalent cancer globally, necessitating comprehensive care. A multidisciplinary approach proves crucial for precise diagnosis and treatment, ultimately leading to effective disease management. While surgical interventions continue to evolve and remain integral for curative treatment, imaging assumes a fundamental role in breast cancer detection. Advanced imaging techniques not only facilitate improved diagnosis but also contribute significantly to the overall enhancement of breast cancer management. This review article aims to provide an overview of innovative technologies such as virtual reality, augmented reality, and three-dimensional imaging, utilized in the medical field to elevate the diagnosis and treatment of breast cancer. Additionally, the article delves into an emerging technology known as the metaverse, still under development. Through the analysis of impactful research and comparison of their findings, this study offers valuable insights into the advantages of each innovative technique. The goal is to provide physicians, surgeons, and radiologists with information on how to enhance breast cancer management.
    Language English
    Publishing date 2024-02-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply to: Tumour Biology and lack of standardization in assessment of ypT0 has an impact on survival in patients with locally advanced rectal cancers achieving complete pathological response after neoadjuvant chemoradiation.

    Lorenzon, Laura / Polom, Karol

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2020  Volume 46, Issue 8, Page(s) 1562–1563

    MeSH term(s) Biology ; Humans ; Neoadjuvant Therapy ; Rectal Neoplasms ; Rectum ; Reference Standards
    Language English
    Publishing date 2020-04-29
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2020.04.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1149: Show issues Location:
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    Zs.MO 549: Show issues

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  4. Article ; Online: Complete Mesogastric Excisions Involving Anatomically Based Concepts and Embryological-Based Surgeries: Current Knowledge and Future Challenges.

    Girnyi, Sergii / Ekman, Marcin / Marano, Luigi / Roviello, Franco / Połom, Karol

    Current oncology (Toronto, Ont.)

    2021  Volume 28, Issue 6, Page(s) 4929–4937

    Abstract: Surgeries for gastrointestinal tract malignancies are based on the paradigm that we should remove the tumour together with its lymphatic drainage in one block. This concept was initially proposed in rectal surgery and called a total mesorectal excision. ... ...

    Abstract Surgeries for gastrointestinal tract malignancies are based on the paradigm that we should remove the tumour together with its lymphatic drainage in one block. This concept was initially proposed in rectal surgery and called a total mesorectal excision. This procedure gained much interest and has improved oncological results in rectal cancer surgery. The same idea for mesogastric and complete mesogastric excisions was proposed but, because of the complexity of the gastric mesentery, it has not become a standard technique. In this review, we analysed anatomical and embryological factors, proposed technical aspects of this operation and incorporated the available initial results of this concept. We also discussed analogies to other gastrointestinal organs, as well as challenges to this concept.
    MeSH term(s) Gastrectomy/methods ; Humans ; Lymph Node Excision/methods ; Mesentery/pathology ; Mesentery/surgery ; Rectal Neoplasms/pathology ; Rectal Neoplasms/surgery ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery
    Language English
    Publishing date 2021-11-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol28060413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4305: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Gut Microbiota Modulation in the Context of Immune-Related Aspects of

    Kaźmierczak-Siedlecka, Karolina / Roviello, Giandomenico / Catalano, Martina / Polom, Karol

    Nutrients

    2021  Volume 13, Issue 8

    Abstract: Accumulating evidence has revealed the critical roles of commensal microbes in cancer progression and recently several investigators have evaluated the therapeutic effectiveness of targeting the microbiota. This gut microbiota-related approach is ... ...

    Abstract Accumulating evidence has revealed the critical roles of commensal microbes in cancer progression and recently several investigators have evaluated the therapeutic effectiveness of targeting the microbiota. This gut microbiota-related approach is especially attractive in the treatment of gastrointestinal cancers. Probiotics supplementation is a microbiota-targeted strategy that appears to improve treatment efficacy;
    MeSH term(s) Akkermansia ; Animals ; Bacteria ; Bifidobacterium ; Gastrointestinal Microbiome/immunology ; Gastrointestinal Neoplasms/immunology ; Gastrointestinal Neoplasms/microbiology ; Humans ; Immune System ; Immunomodulation ; Lactobacillus ; Probiotics/administration & dosage
    Language English
    Publishing date 2021-07-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu13082674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Can Social Media Profiles Be a Reliable Source of Information on Nutrition and Dietetics?

    Kabata, Paweł / Winniczuk-Kabata, Dorota / Kabata, Piotr Maciej / Jaśkiewicz, Janusz / Połom, Karol

    Healthcare (Basel, Switzerland)

    2022  Volume 10, Issue 2

    Abstract: Background: Social media are growing worldwide platforms for unlimited exchange of various content. Owing to their accessibility and short form, they can be utilized as usable, wide-range communication and information tools for companies, scientific ... ...

    Abstract Background: Social media are growing worldwide platforms for unlimited exchange of various content. Owing to their accessibility and short form, they can be utilized as usable, wide-range communication and information tools for companies, scientific communities, patient advocacy organizations, and special interest groups. This study aimed to investigate whether Instagram
    Materials and methods: Random identification of nutrition-related posts was performed using a built-in website search engine. Posts were searched by five popular hashtags: #nutrition, #nutritionist, #instadiet, #diet, and #dietitian, 250 newest posts of each. Advertisement posts were discarded. Each eligible post was then categorized (dietetics, fitness, motivation, other) and assessed with regard to the quality of nutrition information provided (five levels from none to good quality), popularity (number of followers, likes, and comments), and engagement measures (like, comment, and engagement ratio).
    Results: A total of 1189 posts were reviewed. The overall quality of the content regarding nutritional knowledge was extremely low (93.9% of all posts), also when divided into categories. Among all posts, 63.8% were categorized as "nutrition and dietetics", while "fitness", "motivation", and "other" categories comprised 8.2%, 4.8%, and 23.2% of the posts, respectively. Posts recognized as dietetics were the most liked (mean
    Conclusions: Random post search cannot provide viewers with valuable nutrition information. A dedicated search for high-quality professional profiles is preferred to obtain quality information.
    Language English
    Publishing date 2022-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10020397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sodium butyrate in both prevention and supportive treatment of colorectal cancer.

    Kaźmierczak-Siedlecka, Karolina / Marano, Luigi / Merola, Elvira / Roviello, Franco / Połom, Karol

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 1023806

    Abstract: Accumulating evidence suggests that selected microbiota-derived metabolites play a significant role in both tumor prevention and supportive treatment of cancer. Short-chain fatty acids (SCFAs), i.e., mainly acetate, proprionate, and butyrate, are one of ... ...

    Abstract Accumulating evidence suggests that selected microbiota-derived metabolites play a significant role in both tumor prevention and supportive treatment of cancer. Short-chain fatty acids (SCFAs), i.e., mainly acetate, proprionate, and butyrate, are one of them. Nowadays, it is known that butyrate is a key microbial metabolite. Therefore, in the current review, we focused on butyrate and sodium butyrate (NaB) in the context of colorectal cancer. Notably, butyrate is characterized by a wide range of beneficial properties/activities. Among others, it influences the function of the immune system, maintains intestinal barrier integrity, positively affects the efficiency of anti-cancer treatment, and may reduce the risk of mucositis induced by chemotherapy. Taking into consideration these facts, we analyzed NaB (which is a salt of butyric acid) and its impact on gut microbiota as well as anti-tumor activity by describing molecular mechanisms. Overall, NaB is available as, for instance, food with special medical purposes (depending on the country's regulation), and its administration seems to be a promising option for colorectal cancer patients.
    MeSH term(s) Humans ; Butyric Acid/therapeutic use ; Fatty Acids, Volatile/metabolism ; Gastrointestinal Microbiome/physiology ; Microbiota ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/prevention & control
    Chemical Substances Butyric Acid (107-92-6) ; Fatty Acids, Volatile
    Language English
    Publishing date 2022-10-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.1023806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Fluorescence Imaging in Colorectal Surgery: An Updated Review and Future Trends.

    Daniluk, Paulina / Mazur, Natalia / Swierblewski, Maciej / Chand, Manish / Diana, Michele / Polom, Karol

    Surgical innovation

    2022  Volume 29, Issue 4, Page(s) 479–487

    Abstract: Fluorescence imaging in colorectal surgery is considered a novel predominantly intraoperative method of ensuring a greater surgical success. The use of fluorescence is linked to advanced tumor visualization and projection of its lymphatics, both vessels ... ...

    Abstract Fluorescence imaging in colorectal surgery is considered a novel predominantly intraoperative method of ensuring a greater surgical success. The use of fluorescence is linked to advanced tumor visualization and projection of its lymphatics, both vessels and nodes, which results in a higher chance of achieving a total excision. Additionally, iatrogenic complications prove to be reduced using fluorescence during the surgical excision. The combination of fluorescence and artificial intelligence to better facilitate oncological surgery will soon become an established approach in operating rooms worldwide.
    MeSH term(s) Artificial Intelligence ; Colorectal Surgery ; Digestive System Surgical Procedures ; Fluorescence ; Indocyanine Green ; Optical Imaging/methods
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2182571-3
    ISSN 1553-3514 ; 1553-3506
    ISSN (online) 1553-3514
    ISSN 1553-3506
    DOI 10.1177/15533506211072678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4269: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Near-Infrared Fluorescence Image-Guided Surgery in Esophageal and Gastric Cancer Operations.

    Ekman, Marcin / Girnyi, Sergii / Marano, Luigi / Roviello, Franco / Chand, Manish / Diana, Michele / Polom, Karol

    Surgical innovation

    2022  Volume 29, Issue 4, Page(s) 540–549

    Abstract: Background: Near-infrared fluorescence image-guided surgery helps surgeons to see beyond the classical eye vision. Over the last few years, we have witnessed a revolution which has begun in the field of image-guided surgery.: Purpose, and research ... ...

    Abstract Background: Near-infrared fluorescence image-guided surgery helps surgeons to see beyond the classical eye vision. Over the last few years, we have witnessed a revolution which has begun in the field of image-guided surgery.
    Purpose, and research design: Fluorescence technology using indocyanine green (ICG) has shown promising results in many organs, and in this review article, we wanted to discuss the 6 main domains where fluorescence image-guided surgery is currently used for esophageal and gastric cancer surgery.
    Study sample and data collection: Visualization of lymphatic vessels, tumor localization, fluorescence angiography for anastomotic evaluation, thoracic duct visualization, tracheal blood flow analysis, and sentinel node biopsy are discussed.
    Conclusions: It seems that this technology has already found its place in surgery. However, new possibilities and research avenues in this area will probably make it even more important in the near future.
    MeSH term(s) Esophageal Neoplasms/diagnostic imaging ; Esophageal Neoplasms/surgery ; Fluorescence ; Humans ; Indocyanine Green ; Sentinel Lymph Node Biopsy/methods ; Stomach Neoplasms/diagnostic imaging ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery ; Surgery, Computer-Assisted
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2022-03-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2182571-3
    ISSN 1553-3514 ; 1553-3506
    ISSN (online) 1553-3514
    ISSN 1553-3506
    DOI 10.1177/15533506211073417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4269: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Insights into oral microbiome and colorectal cancer - on the way of searching new perspectives.

    Kudra, Anna / Muszyński, Damian / Sobocki, Bartosz Kamil / Atzeni, Alessandro / Carbone, Ludovico / Kaźmierczak-Siedlecka, Karolina / Połom, Karol / Kalinowski, Leszek

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1159822

    Abstract: Microbiome is a keystone polymicrobial community that coexist with human body in a beneficial relationship. These microorganisms enable the human body to maintain homeostasis and take part in mechanisms of defense against infection and in the absorption ... ...

    Abstract Microbiome is a keystone polymicrobial community that coexist with human body in a beneficial relationship. These microorganisms enable the human body to maintain homeostasis and take part in mechanisms of defense against infection and in the absorption of nutrients. Even though microbiome is involved in physiologic processes that are beneficial to host health, it may also cause serious detrimental issues. Additionally, it has been proven that bacteria can migrate to other human body compartments and colonize them even although significant structural differences with the area of origin exist. Such migrations have been clearly observed when the causes of genesis and progression of colorectal cancer (CRC) have been investigated. It has been demonstrated that the oral microbiome is capable of penetrating into the large intestine and cause impairments leading to dysbiosis and stimulation of cancerogenic processes. The main actors of such events seem to be oral pathogenic bacteria belonging to the red and orange complex (regarding classification of bacteria in the context of periodontal diseases), such as
    MeSH term(s) Humans ; Periodontal Diseases/microbiology ; Porphyromonas gingivalis ; Microbiota ; Virulence Factors ; Fusobacterium nucleatum ; Colorectal Neoplasms
    Chemical Substances Virulence Factors
    Language English
    Publishing date 2023-04-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1159822
    Database MEDical Literature Analysis and Retrieval System OnLINE

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