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  1. Article: Sigmoid Colon Intraluminal Obstruction by a Detached Recurrent Ascending Colon Liposarcoma.

    Petropoulou, Thalia / Evangelou, Kyriacos / Polydorou, Andreas

    Cureus

    2024  Volume 16, Issue 4, Page(s) e58065

    Abstract: Primary liposarcoma of the colon is extremely rare in the literature. We present a case of a 51-year-old male patient with recurrent ascending colon liposarcoma, which caused obstructive ileus, just a few days prior to his scheduled elective operation ... ...

    Abstract Primary liposarcoma of the colon is extremely rare in the literature. We present a case of a 51-year-old male patient with recurrent ascending colon liposarcoma, which caused obstructive ileus, just a few days prior to his scheduled elective operation and led us to expedite his surgery. The procedure was scheduled to be a robotic right colectomy. After finishing the operation and extracting the specimen, the tumour could not be detected; hence, an exploratory laparotomy was performed. Findings were a large tumour in the sigmoid colon, causing complete obstruction. Sigmoidectomy was performed, in order to remove the tumour. To our knowledge, this is the first case published in the literature, reporting a colonic tumour detachment, displacement and causing distal bowel occlusion. This event highlights the importance of careful intraoperative inspection in patients with known intraluminal bowel malignancies that present with signs and symptoms of obstruction and emphasises the need for further research on the risk factors for tumour detachment and subsequent bowel occlusion.
    Language English
    Publishing date 2024-04-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.58065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: First robotic CME in Europe with augmented reality tools.

    Petropoulou, T / Polydorou, A / Amin, S

    Techniques in coloproctology

    2021  Volume 25, Issue 7, Page(s) 887–888

    MeSH term(s) Augmented Reality ; Europe ; Humans ; Robotic Surgical Procedures ; Robotics
    Language English
    Publishing date 2021-01-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-021-02413-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The contribution of oncovascular surgery in a young patient with idiopathic retroperitoneal fibrosis.

    Kotsis, Thomas / Christoforou, Panagitsa / Polydorou, Andreas

    Journal of surgical case reports

    2022  Volume 2022, Issue 1, Page(s) rjab589

    Abstract: Surgical resection remains the cornerstone for the treatment of oncological disease. When a critical arterial or venous structure is involved in a tumor mass, successful relief of symptoms and long-term oncological control are achieved through careful ... ...

    Abstract Surgical resection remains the cornerstone for the treatment of oncological disease. When a critical arterial or venous structure is involved in a tumor mass, successful relief of symptoms and long-term oncological control are achieved through careful preoperative planning by an interdisciplinary team that necessarily includes a vascular surgeon. We describe the involvement of a vascular surgeon in the oncology of a 22-year-old woman, who is diagnosed with idiopathic retroperitoneal fibrosis.
    Language English
    Publishing date 2022-01-17
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjab589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: First robotic natural orifice transluminal extraction colectomy in Europe: new technique for optimizing results - a video vignette.

    Petropoulou, Thalia / Bakas, Aris / Tataridi, Olga / Gallou, Jolanda / Polydorou, Andreas

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 25, Issue 5, Page(s) 1057–1058

    MeSH term(s) Humans ; Robotic Surgical Procedures ; Colectomy ; Robotics ; Europe ; Natural Orifice Endoscopic Surgery ; Laparoscopy
    Language English
    Publishing date 2022-12-13
    Publishing country England
    Document type Video-Audio Media ; Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Solid Pseudopapillary Tumor of the Pancreas in a 25-Year-Old Female: A Rare Entity of Pancreatic Tumors.

    Massaras, Dimitrios / Masourou, Zoi / Papazian, Maria / Psarras, Grigorios / Polydorou, Andreas

    Cureus

    2021  Volume 13, Issue 4, Page(s) e14747

    Abstract: Solid pseudopapillary neoplasms (SPMs) of the pancreas are extremely rare tumors of the pancreas that typically affect young women and have a favorable prognosis. Herein, we report a 25-year-old female with solid pseudopapillary tumor of the pancreas who ...

    Abstract Solid pseudopapillary neoplasms (SPMs) of the pancreas are extremely rare tumors of the pancreas that typically affect young women and have a favorable prognosis. Herein, we report a 25-year-old female with solid pseudopapillary tumor of the pancreas who presented with atypical epigastric pain. The patient underwent pancreatoduodenectomy (Whipple procedure). She remained asymptomatic and showed no signs of disease after one year of follow-up. This type of pancreatic tumors is amenable to cure after complete surgical resection, even in cases with capsular invasion, unlike any other malignant tumors of the pancreas.
    Language English
    Publishing date 2021-04-29
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.14747
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Bilateral palsy of the hypoglossal nerve following general anesthesia for emergency surgery. A case report.

    Brattou, Panagiota / Iliakopoulos, Konstantinos / Anagnostou, Evangelos / Zambelis, Thomas / Polydorou, Andreas / Theodoraki, Kassiani

    International journal of surgery case reports

    2022  Volume 96, Page(s) 107387

    Abstract: Introduction and importance: Hypoglossal nerve palsy is a rare condition usually associated with tumors, trauma, stroke or multiple sclerosis. It can be associated with other cranial nerve palsies while injury to this nerve typically affects a patient's ...

    Abstract Introduction and importance: Hypoglossal nerve palsy is a rare condition usually associated with tumors, trauma, stroke or multiple sclerosis. It can be associated with other cranial nerve palsies while injury to this nerve typically affects a patient's articulation by causing lingual motility disturbance and swallowing difficulty. Bilateral isolated hypoglossal nerve palsy is an even more infrequent condition, which can occasionally be due to airway manipulation.
    Case presentation: We describe a case of bilateral hypoglossal nerve damage following general anesthesia for emergency surgery, presenting with dysarthria, immobility of the tongue and dysphagia after extubation. The patient had a gradual recovery of all lost functions during the next four months.
    Clinical discussion: Bilateral hypoglossal nerve palsy is a very rare entity and tracheal tube malposition or prolonged but unnoticed tracheal cuff pressure especially in the face of low blood pressure, should be considered as possible causative mechanisms for this condition. This underlines the importance of careful positioning of the patient's head and neck during surgery as well as the meticulous and correct performance of routine maneuvers of airway management.
    Conclusion: Bilateral hypoglossal nerve palsy is a very rare entity. Diagnosis and management of twelfth nerve palsy require a multidisciplinary approach to achieve the best patient outcome.
    Language English
    Publishing date 2022-07-05
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2022.107387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: An investigation into the cytotoxic effects of microbubbles and their constituents on osteosarcoma and bone marrow stromal cells.

    Polydorou, A E / May, J P / Makris, K / Ferri, S / Wu, Q / Stride, E / Carugo, D / Evans, N D

    Biochimica et biophysica acta. General subjects

    2023  Volume 1867, Issue 12, Page(s) 130481

    Abstract: Background: Ultrasound-responsive microbubbles offer a means of achieving minimally invasive, localised drug delivery in applications including regenerative medicine. To facilitate their use, however, it is important to determine any cytotoxic effects ... ...

    Abstract Background: Ultrasound-responsive microbubbles offer a means of achieving minimally invasive, localised drug delivery in applications including regenerative medicine. To facilitate their use, however, it is important to determine any cytotoxic effects they or their constituents may have. The aim of this study was to test the hypothesis that phospholipid-shelled microbubbles are non-toxic to human bone-derived cells at biologically-relevant concentrations.
    Methods: Microbubbles were fabricated using combinations of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), 1,2-dibehenoyl-sn-glycero-3-phosphocholine (DBPC), polyoxyethylene(40) stearate (PEG40S) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene-glycol)-2000] (DSPE-PEG
    Results: DBPC:DSPE-PEG
    Conclusions: These data indicate that, over a broad range of concentrations and incubation times, DBPC:DSPE-PEG
    MeSH term(s) Humans ; Microbubbles ; Phospholipids ; Antineoplastic Agents ; Osteosarcoma/drug therapy
    Chemical Substances 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000) ; Phospholipids ; Antineoplastic Agents
    Language English
    Publishing date 2023-10-05
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 60-7
    ISSN 1872-8006 ; 1879-2596 ; 1879-260X ; 1879-2642 ; 1879-2618 ; 1879-2650 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    ISSN (online) 1872-8006 ; 1879-2596 ; 1879-260X ; 1879-2642 ; 1879-2618 ; 1879-2650
    ISSN 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    DOI 10.1016/j.bbagen.2023.130481
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Pancreatic intraductal papillary mucinous neoplasm masquerading as ampullary adenoma: a diagnostic puzzle.

    Dellaportas, Dionysios / Fragulidis, George / Polydorou, Andreas / Vezakis, Antonios

    Annals of gastroenterology

    2019  Volume 33, Issue 1, Page(s) 98–100

    Abstract: Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cystic lesion, remaining mostly asymptomatic. An atypical presentation of such a lesion, initially thought to be an ampullary adenoma, is presented herein. A 78-year-old white ... ...

    Abstract Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cystic lesion, remaining mostly asymptomatic. An atypical presentation of such a lesion, initially thought to be an ampullary adenoma, is presented herein. A 78-year-old white male with painless jaundice was treated in a tertiary hospital. Imaging and endoscopic investigations pointed towards an ampullary adenoma obstructing and causing dilatation of both bile and pancreatic ducts. Endoscopic papillectomy was carried out and histology revealed tubulovillous adenoma. Follow-up duodenoscopy 3 months later showed a recurrent lesion with mucous leaking from the pancreatic duct. Cytology revealed mucin-rich atypical cells, consistent with main-duct IPMN. Pancreatoduodenectomy was performed, finally revealing main-duct IPMN protruding through Vater's ampulla. Cystic pancreatic lesions are increasingly found and IPMN is the most common of these. On the other hand, the management of ampullary adenomas has been revolutionized by endoscopic treatment and the advent of endoscopic papillectomy, with expanding indications. Meticulous clinical and imaging work up of these patients is essential to avoid suboptimal treatment. IPMN should be included in the differential diagnosis of ampullary adenomas, especially in the presence of a grossly dilated pancreatic duct.
    Language English
    Publishing date 2019-11-29
    Publishing country Greece
    Document type Case Reports
    ZDB-ID 2032850-3
    ISSN 1108-7471
    ISSN 1108-7471
    DOI 10.20524/aog.2019.0435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Primary malignant fibrous histiocytoma of the liver.

    Fragulidis, Georgios P / Polydorou, Andreas

    Hepatobiliary surgery and nutrition

    2016  Volume 5, Issue 5, Page(s) 449–450

    Language English
    Publishing date 2016-10-25
    Publishing country China (Republic : 1949- )
    Document type Case Reports
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn.2016.09.05
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Distal pancreatectomy after pancreatic injury, in two pediatric patients.

    Hadjizacharias, Theodoros / Kaliviotis, Ioannis / Kottakis, George / Pavlides, Orestis / Papalouka, Dimitra / Polydorou, Andreas

    International journal of surgery case reports

    2020  Volume 76, Page(s) 293–296

    Abstract: Introduction: Although serious trauma is rare in pediatric patients, the management of blunt force trauma to the abdomen remains a challenge for Child Surgery Departments. Pancreatic injury comprises the fourth most common injury among the solid organs ... ...

    Abstract Introduction: Although serious trauma is rare in pediatric patients, the management of blunt force trauma to the abdomen remains a challenge for Child Surgery Departments. Pancreatic injury comprises the fourth most common injury among the solid organs and cases accompanied by rupture of the main pancreatic duct (MPD) present a further challenge for physicians (Fayza Haider et al.; Wood et al., 2010; Jobst et al., 1999; Grosfeld et al., 2006).
    Case presentation: Two adolescents, both 13 years old, where referred to our Pediatric Hospital, due to blunt force abdominal trauma. During admission, both patients were hemodynamically stable, in good general condition but suffering from abdominal pain and vomiting. After a full diagnostic check-up, grade IV pancreatic injury was diagnosed in both patients and they were taken to the operation room 3 and 6 days post-injury. Intra-operatively a distal pancreatectomy along with splenectomy was performed in both cases, with catheterization and ligation of the main pancreatic duct. Both patients were admitted to the pediatric ICU for 2 and 4 days. Both made an uneventful recovery and remain well 6 months postoperatively.
    Conclusion: While hemodynamically stable, patients with Grade IV pancreatic injury, benefit from sub-acute management, allowing for planning of the surgical intervention. Distal pancreatectomy with splenectomy, along with catheterization and ligation of the main pancreatic duct, has excellent post-operative results. The chief of the Pediatric Hospital, said that in 35 years at pediatric surgery, is the first time with the need of operative management, in pancreatic injury. The hepatobiliary surgical expert in adults, who was consulted in both cases, said that without the surgeries, both children were going to die.
    Language English
    Publishing date 2020-10-07
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2020.10.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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