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  1. Article ; Online: Diverse impact of national guidelines: do all surgeons have access to changes?

    Pompili, Cecilia

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2022  Volume 62, Issue 2

    MeSH term(s) Clinical Competence ; Humans ; Surgeons
    Language English
    Publishing date 2022-08-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezac419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: What my life will be like after surgery?

    Pompili, Cecilia

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2022  Volume 62, Issue 3

    MeSH term(s) Carcinoma, Non-Small-Cell Lung/surgery ; Hospitals ; Humans ; Lung Neoplasms/surgery ; Thoracic Surgery, Video-Assisted ; Thoracotomy
    Language English
    Publishing date 2022-09-08
    Publishing country Germany
    Document type Editorial ; Comment
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezac224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Shared Decision Making and Human Bias.

    Pompili, Cecilia / Brunelli, Alessandro

    The Annals of thoracic surgery

    2022  Volume 115, Issue 2, Page(s) 361–362

    MeSH term(s) Humans ; Decision Making, Shared ; Decision Making ; Physician-Patient Relations ; Patient Participation
    Language English
    Publishing date 2022-01-18
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2021.12.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Cohort study investigating evolution and factors associated with dyspnoea after anatomic lung resection.

    Pompili, Cecilia / Tariq, Javeria / Dalmia, Sanjush / Harle, Amelie / Gilbert, Alexandra / Valuckiene, Laura / Brunelli, Alessandro

    Journal of thoracic disease

    2024  Volume 16, Issue 1, Page(s) 113–122

    Abstract: Background: Dyspnoea is common following surgical resection for non-small cell lung cancer (NSCLC). The effects range from reduced quality of life to impact on adjuvant therapy outcomes. Currently, dyspnoea beyond the immediate postoperative phase and ... ...

    Abstract Background: Dyspnoea is common following surgical resection for non-small cell lung cancer (NSCLC). The effects range from reduced quality of life to impact on adjuvant therapy outcomes. Currently, dyspnoea beyond the immediate postoperative phase and risk factors are not well characterised. We hope to assess the evolution of patient-reported dyspnoea after anatomic lung resection and associated factors.
    Methods: Single-centre cohort study with analysis on data collected longitudinally of 131 patients undergoing anatomic lung resections for NSCLC between September 2014 and December 2018. The European Organization for Research and Treatment Lung Cancer-specific Quality of Life Questionnaire Dyspnoea Scale was used to measure dyspnoea before and after surgery. Multivariable regression analysis was used to identify factors associated with clinically meaningful perioperative changes in dyspnoea at 6-12 months.
    Results: Mean Dyspnoea Scale scores preoperatively and 6-12 months after resection were 12.6 (standard deviation 17.4) and 17.9 (standard deviation 20.5), respectively. Of all patients 31% experienced a clinically meaningful increase in dyspnoea, defined as >10 points between Dyspnoea Scale scores preoperatively and at 6-12 months. Comparatively, 71% of patients without preoperative symptoms of dyspnoea developed a clinically meaningful increase of dyspnoea postoperatively. After adjusting the analysis for baseline factors and preoperative Dyspnoea Scale score, female sex remained the only patient factor associated with increased postoperative dyspnoea at 6-12 months after surgery (P=0.046). A total of 34% of patients reported increased dyspnoea after lobectomies and 9% after segmentectomies (P=0.014). Segmentectomy (as opposed to larger resections) was the only surgical factor associated with lower risk of increased dyspnoea (P=0.057).
    Conclusions: A clinically meaningful increase in dyspnoea is frequent after lung resection. Postoperative evolution of dyspnoea is non-predictable using objective baseline factors highlighting the importance of patient reported symptoms and involvement in clinical consultation.
    Language English
    Publishing date 2024-01-15
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-23-835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: FRET-Sensing of Multivalent Protein Binding at the Interface of Biomimetic Microparticles Functionalized with Fluorescent Glycolipids.

    Michelis, Sophie / Pompili, Chiara / Niedergang, Florence / Fattaccioli, Jacques / Dumat, Blaise / Mallet, Jean-Maurice

    ACS applied materials & interfaces

    2024  Volume 16, Issue 8, Page(s) 9669–9679

    Abstract: Cell adhesion is a central process in cellular communication and regulation. Adhesion sites are triggered by specific ligand-receptor interactions inducing the clustering of both partners at the contact point. Investigating cell adhesion using microscopy ...

    Abstract Cell adhesion is a central process in cellular communication and regulation. Adhesion sites are triggered by specific ligand-receptor interactions inducing the clustering of both partners at the contact point. Investigating cell adhesion using microscopy techniques requires targeted fluorescent particles with a signal sensitive to the clustering of receptors and ligands at the interface. Herein, we report on simple cell or bacterial mimics, based on liquid microparticles made of lipiodol functionalized with custom-designed fluorescent lipids. These lipids are targeted toward lectins or biotin membrane receptors, and the resulting particles can be specifically identified and internalized by cells, as demonstrated by their phagocytosis in primary murine bone marrow-derived macrophages. We also evidence the possibility to sense the binding of a multivalent lectin, concanavalin A, in solution by monitoring the energy transfer between two matching fluorescent lipids on the surface of the particles. We anticipate that these liquid particle-based sensors, which are able to report via Förster resonance energy transfer (FRET) on the movement of ligands on their interface upon protein binding, will provide a useful tool to study receptor binding and cooperation during adhesion processes such as phagocytosis.
    MeSH term(s) Animals ; Mice ; Fluorescence Resonance Energy Transfer/methods ; Protein Binding ; Biomimetics ; Glycolipids ; Lectins/metabolism ; Ligands ; Coloring Agents
    Chemical Substances Glycolipids ; Lectins ; Ligands ; Coloring Agents
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c15067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Time for change: women leading in cardiothoracic surgery, a global perspective.

    Pompili, Cecilia / Backhus, Leah

    Journal of thoracic disease

    2020  Volume 13, Issue 1, Page(s) 430–431

    Language English
    Publishing date 2020-09-29
    Publishing country China
    Document type Editorial
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-2020-wts-01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Quality of life after lung resection for lung cancer.

    Pompili, Cecilia

    Journal of thoracic disease

    2014  Volume 7, Issue Suppl 2, Page(s) S138–44

    Abstract: Radical and palliative treatments for non-small cell lung cancer (NSCLC) have been reported to have a significant impact on the patient quality of life (QoL). The increasing improvements in lung cancer diagnosis and cures in recent years have changed the ...

    Abstract Radical and palliative treatments for non-small cell lung cancer (NSCLC) have been reported to have a significant impact on the patient quality of life (QoL). The increasing improvements in lung cancer diagnosis and cures in recent years have changed the perspectives of quantity and quality of the life after cancer in these patients. However, despite a growing interest about patient reported outcome measures (PROMs) in surgical oncology, we are quite distant from a routine collection of QoL data after pulmonary resection for NSCLC. The presence of this gap is due to several reasons: the lack of validated surgical-specific questionnaires, the inappropriate consideration of traditional objective parameters as surrogates of QoL outcomes and the difficulties in dealing with missing items in this type of research. However, a recent the European Society of Thoracic Surgeons (ESTS) survey exploring the use of QoL data in our field has revealed that almost half of the units responding to the questionnaire collect QoL informations from their patients. Increased consensus and collaboration between surgeons are needed to include routinely PROMs in randomized controlled trials. The objective of this paper is to review the best available evidence published in the literature and regarding QoL after lung resection for cancer, aiming at identifying topics deserving further investigations.
    Language English
    Publishing date 2014-12-12
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.3978/j.issn.2072-1439.2015.04.40
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Women in Thoracic Surgery in Africa: a call for intersocietal coalition.

    Pompili, Cecilia / Ugalde Figueroa, Paula / Molena, Daniela / Lerut, Toni

    Interactive cardiovascular and thoracic surgery

    2022  Volume 34, Issue 5, Page(s) 721–722

    MeSH term(s) Africa ; Female ; Humans ; Thoracic Surgery
    Language English
    Publishing date 2022-01-12
    Publishing country England
    Document type Editorial
    ZDB-ID 2095298-3
    ISSN 1569-9285 ; 1569-9293
    ISSN (online) 1569-9285
    ISSN 1569-9293
    DOI 10.1093/icvts/ivab368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The role of patient-reported outcome and experience measures in cardio-thoracic surgery.

    Pompili, Cecilia / Scheenstra, Bart / Zirafa, Carmelina / Melfi, Franca / De Rosis, Sabina / Vainieri, Milena / Lau, Kelvin / Sardari Nia, Peyman

    Interdisciplinary cardiovascular and thoracic surgery

    2024  Volume 38, Issue 3

    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivae025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Editorial: Current trends in endoscopic thoracic surgery: insights from the XXI SIET national meeting.

    Raveglia, Federico / Melfi, Franca / Cioffi, Ugo / Lococo, Filippo / Ricciardi, Sara / Pompili, Cecilia / Cardillo, Giuseppe

    Frontiers in surgery

    2023  Volume 10, Page(s) 1237928

    Language English
    Publishing date 2023-06-30
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2023.1237928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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