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  1. Article ; Online: Prediction of lung cancer risk for radon exposures based on cellular alpha particle hits.

    Truta-Popa, L-A / Hofmann, W / Cosma, C

    Radiation protection dosimetry

    2011  Volume 145, Issue 2-3, Page(s) 218–223

    Abstract: To explore the role of the multiplicity of cellular hits by radon progeny alpha particles for lung cancer incidence, the number of single and multiple alpha particle hits were computed for basal and secretory cells in the bronchial epithelium of human ... ...

    Abstract To explore the role of the multiplicity of cellular hits by radon progeny alpha particles for lung cancer incidence, the number of single and multiple alpha particle hits were computed for basal and secretory cells in the bronchial epithelium of human airway bifurcations. Hot spots of alpha particle hits were observed at the branching points of bronchial airway bifurcations. The effect of single and multiple alpha particle intersections of bronchial cells during a given exposure period, selected from a Poisson distribution, on lung cancer risk were simulated by a transformation frequency--tissue response model, based on experimentally observed cellular transformation and survival functions. Calculations of lung cancer risk at low radon exposure levels suggest that single hits produce a linear-dose response relationship, while the superposition of single and increasing multiple hits at higher exposure levels may also be approximated by a quasi-linear dose-effect curve. The simulations predict a carcinogenic enhancement effect for radon progeny accumulations at bifurcation branching sites, which may increase current risk estimates.
    MeSH term(s) Alpha Particles/adverse effects ; Animals ; Bronchi/radiation effects ; Epithelial Cells/radiation effects ; Humans ; Lung Neoplasms/etiology ; Mice ; Mice, Inbred C3H ; Neoplasms, Radiation-Induced/etiology ; Predictive Value of Tests ; Radon/analysis ; Radon Daughters/analysis ; Rats ; Risk Factors ; Trachea/radiation effects
    Chemical Substances Radon Daughters ; Radon (Q74S4N8N1G)
    Language English
    Publishing date 2011-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncr082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Search for magnetic monopoles produced via the Schwinger mechanism.

    Acharya, B / Alexandre, J / Benes, P / Bergmann, B / Bertolucci, S / Bevan, A / Branzas, H / Burian, P / Campbell, M / Cho, Y M / de Montigny, M / De Roeck, A / Ellis, J R / Sawy, M El / Fairbairn, M / Felea, D / Frank, M / Gould, O / Hays, J /
    Hirt, A M / Ho, D L-J / Hung, P Q / Janecek, J / Kalliokoski, M / Korzenev, A / Lacarrère, D H / Leroy, C / Levi, G / Lionti, A / Maulik, A / Margiotta, A / Mauri, N / Mavromatos, N E / Mermod, P / Millward, L / Mitsou, V A / Ostrovskiy, I / Ouimet, P-P / Papavassiliou, J / Parker, B / Patrizii, L / Păvălaş, G E / Pinfold, J L / Popa, L A / Popa, V / Pozzato, M / Pospisil, S / Rajantie, A / de Austri, R Ruiz / Sahnoun, Z / Sakellariadou, M / Santra, A / Sarkar, S / Semenoff, G / Shaa, A / Sirri, G / Sliwa, K / Soluk, R / Spurio, M / Staelens, M / Suk, M / Tenti, M / Togo, V / Tuszyn'ski, J A / Upreti, A / Vento, V / Vives, O

    Nature

    2022  Volume 602, Issue 7895, Page(s) 63–67

    Abstract: Electrically charged particles can be created by the decay of strong enough electric fields, a phenomenon known as the Schwinger ... ...

    Abstract Electrically charged particles can be created by the decay of strong enough electric fields, a phenomenon known as the Schwinger mechanism
    Language English
    Publishing date 2022-02-02
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-021-04298-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: First Search for Dyons with the Full MoEDAL Trapping Detector in 13 TeV pp Collisions.

    Acharya, B / Alexandre, J / Benes, P / Bergmann, B / Bernabéu, J / Bevan, A / Branzas, H / Burian, P / Campbell, M / Cecchini, S / Cho, Y M / de Montigny, M / De Roeck, A / Ellis, J R / El Sawy, M / Fairbairn, M / Felea, D / Frank, M / Hays, J /
    Hirt, A M / Janecek, J / Kalliokoski, M / Korzenev, A / Lacarrère, D H / Leroy, C / Levi, G / Lionti, A / Mamuzic, J / Maulik, A / Margiotta, A / Mauri, N / Mavromatos, N E / Mermod, P / Mieskolainen, M / Millward, L / Mitsou, V A / Orava, R / Ostrovskiy, I / Ouimet, P-P / Papavassiliou, J / Parker, B / Patrizii, L / Păvălaş, G E / Pinfold, J L / Popa, L A / Popa, V / Pozzato, M / Pospisil, S / Rajantie, A / Ruiz de Austri, R / Sahnoun, Z / Sakellariadou, M / Santra, A / Sarkar, S / Semenoff, G / Shaa, A / Sirri, G / Sliwa, K / Soluk, R / Spurio, M / Staelens, M / Suk, M / Tenti, M / Togo, V / Tuszyński, J A / Upreti, A / Vento, V / Vives, O / Wall, A

    Physical review letters

    2021  Volume 126, Issue 7, Page(s) 71801

    Abstract: The MoEDAL trapping detector consists of approximately 800 kg of aluminum volumes. It was exposed during run 2 of the LHC program to 6.46  fb^{-1} of 13 TeV proton-proton collisions at the LHCb interaction point. Evidence for dyons (particles with ... ...

    Abstract The MoEDAL trapping detector consists of approximately 800 kg of aluminum volumes. It was exposed during run 2 of the LHC program to 6.46  fb^{-1} of 13 TeV proton-proton collisions at the LHCb interaction point. Evidence for dyons (particles with electric and magnetic charge) captured in the trapping detector was sought by passing the aluminum volumes comprising the detector through a superconducting quantum interference device (SQUID) magnetometer. The presence of a trapped dyon would be signaled by a persistent current induced in the SQUID magnetometer. On the basis of a Drell-Yan production model, we exclude dyons with a magnetic charge ranging up to five Dirac charges (5g_{D}) and an electric charge up to 200 times the fundamental electric charge for mass limits in the range 870-3120 GeV and also monopoles with magnetic charge up to and including 5g_{D} with mass limits in the range 870-2040 GeV.
    Language English
    Publishing date 2021-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.126.071801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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