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  1. Article ; Online: Management of groin hernias in emergency setting: differences in indications and outcomes between laparoscopic and open approach. A single-center retrospective experience.

    Sbacco, V / Petrucciani, N / Lauteri, G / Cossa, A / Portinari, M / Brescia, A / Garulli, G

    Langenbeck's archives of surgery

    2024  Volume 409, Issue 1, Page(s) 48

    Abstract: Purpose: The use of minimally invasive groin hernia repair techniques in an emergency setting is still debated and its widespread is limited. The aim of this study is to evaluate the safety and efficacy of the laparoscopic transabdominal preperitoneal ( ... ...

    Abstract Purpose: The use of minimally invasive groin hernia repair techniques in an emergency setting is still debated and its widespread is limited. The aim of this study is to evaluate the safety and efficacy of the laparoscopic transabdominal preperitoneal (TAPP) technique in the treatment of inguinal and femoral hernias in emergency setting based on our experience, comparing indications and outcomes with the open technique.
    Methods: A retrospective analysis was performed including all patients with incarcerated and/or strangulated groin hernia who underwent emergency surgery from November 2019 to September 2022. Perioperative variables and short- and long-term outcomes were examined. Statistical analysis was performed using chi-square test for nominal variables and Student's t test for continuous ones. A p value < 0.05 was considered statistically significant.
    Results: Sixty-six patients were included: 29 patients were treated with TAPP technique (Tapp group) and 37 with open technique plus diagnostic laparoscopy (Open group). Patients in the TAPP group were younger, had less severe clinical scenarios, and had a trend for lower Charlson Comorbidity Index, whereas ASA score and BMI were similar. The small bowel was more frequently herniated in the open group. Bilateral hernia repair was performed in 20.69% of patients in the Tapp group versus 0% in the Open group (p = 0.004). Bowel resection was more frequent in the open group (48.65% vs 0% of the Tapp group, p < 0.001) length of surgery was comparable in the two groups. In the Tapp group, the length of hospitalization was significantly shorter (2.59 ± 2.28 days vs. 9.08 ± 14.48 days; p = 0.023). Postoperative complications, according to Clavien-Dindo, were more severe in Open group where there were two deaths. There were no differences in the number of readmission and re-operations at 30 days and in the recurrence rate.
    Conclusions: Emergency repair of inguinal and femoral hernias using TAPP is a valuable option, safe and feasible in selected patients. In this series, indications for TAPP were reserved to younger patients with less comorbidities and less severe clinical scenario. Future randomized studies are needed to compare TAPP with open emergency hernia surgery in all settings. Potential advantages of TAPP are the reduction of postoperative complications, earlier recovery, and the possibility of bilateral treatment.
    MeSH term(s) Humans ; Hernia, Femoral/surgery ; Retrospective Studies ; Groin/surgery ; Surgical Mesh ; Laparoscopy/methods ; Postoperative Complications/etiology ; Hernia, Inguinal/surgery ; Herniorrhaphy/adverse effects ; Herniorrhaphy/methods ; Treatment Outcome ; Recurrence
    Language English
    Publishing date 2024-01-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-024-03238-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Incisional Hernia After Laparoscopic Right Colectomy for Colorectal Cancer: A Prospective Study with Retrospective Control on Intracorporeal Versus Extracorporeal Anastomosis.

    Pesce, Antonio / Petrarulo, Francesca / Fabbri, Nicolò / Portinari, Mattia / Feo, Carlo Vittorio

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2023  Volume 34, Issue 2, Page(s) 113–119

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Incisional Hernia/epidemiology ; Incisional Hernia/etiology ; Incisional Hernia/surgery ; Retrospective Studies ; Prospective Studies ; Cohort Studies ; Colectomy/adverse effects ; Colectomy/methods ; Colonic Neoplasms/surgery ; Postoperative Complications/etiology ; Anastomosis, Surgical/methods ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Treatment Outcome
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2023.0453
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Obstructed defecation syndrome associated with paradoxical puborectalis contraction: osteopathic treatment versus anal biofeedback. Results of a pilot study.

    Ascanelli, S / Portinari, M / Canella, M / Solari, S / Dall'Omo, F / Danese, S / De Troia, A / Carcoforo, P

    Techniques in coloproctology

    2021  Volume 25, Issue 5, Page(s) 589–595

    Abstract: Background: Biofeedback is the most widespread rehabilitative therapy for the treatment of anismus after failed conservative treatment. Osteopathy represents an alternative therapy for constipation. The aim of this study was to evaluate short- and long- ... ...

    Abstract Background: Biofeedback is the most widespread rehabilitative therapy for the treatment of anismus after failed conservative treatment. Osteopathy represents an alternative therapy for constipation. The aim of this study was to evaluate short- and long-term results of osteopathic treatment as compared to biofeedback in patients with dyssynergic defecation.
    Methods: This was a prospective cohort pilot study on 30 patients with dyssynergic defecation enrolled at the Colorectal Clinic of the University Hospital of Ferrara, Italy, from May 2015 to May 2016 and followed until May 2020. Dyssynergic defecation was defined as the inappropriate contraction of the pelvic floor or less than 20% relaxation of basal resting sphincter pressure (on anal manometry) with adequate propulsive forces during attempted defecation. Dyssynergic patients were divide into 2 treatment groups: 15 patients had osteopathy and 15 patients had biofeedback. Before and 3 months after rehabilitation treatment, all patients had anorectal manometry, defecography, and ultrasound, and were evaluated with the Cleveland Clinic Florida (CCF) constipation score, obstructed defecation syndrome (ODS) score, Colo-rectal-anal Distress Inventory (CRADI-8), Colo-rectal-anal Impact Questionnaire (CRAIQ-7), and the Brusciano Score (BS). To evaluate the efficacy of osteopathy and biofeedback in the long-term, all patients completed the above-mentioned questionnaires 5 years later via a telephone interview.
    Results: The two treatments were similarly effective in the short term with reduction in questionnaires scores, and increase in the percentage of anal sphincter release at straining at anorectal manometry in both groups. The ODS score was significantly reduced in biofeedback group (p = 0.021). The 3-month post-treatment BS was lower in the osteopathy group, but this just failed to reach statistical significance (p = 0.050). Periodic rehabilitation reinforcements were provided. The CCF constipation score decreased significantly in the osteopathy group (p = 0.023) after 5 years.
    Conclusions: Osteopathy is a promising treatment for dyssynergic defecation, and it can be associated with biofeedback.
    MeSH term(s) Anal Canal ; Biofeedback, Psychology ; Constipation/etiology ; Constipation/therapy ; Defecation ; Humans ; Italy ; Manometry ; Pelvic Floor ; Pilot Projects ; Prospective Studies
    Language English
    Publishing date 2021-02-27
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-020-02381-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Radioguided sentinel lymph node biopsy in patients with papillary thyroid carcinoma.

    Portinari, Mattia / Carcoforo, Paolo

    Gland surgery

    2017  Volume 5, Issue 6, Page(s) 591–602

    Abstract: Background: The ATA guidelines do not recommend prophylactic central compartment neck dissection in patients with T1-T2 papillary thyroid carcinoma (PTC) with no clinical evidence of lymph node metastasis, however patients' staging is recommended. Lymph ...

    Abstract Background: The ATA guidelines do not recommend prophylactic central compartment neck dissection in patients with T1-T2 papillary thyroid carcinoma (PTC) with no clinical evidence of lymph node metastasis, however patients' staging is recommended. Lymph node metastasis may be present also in small PTC, but preoperative ultrasound identifies suspicious cervical lymphadenopathy in 20-30% of patients. The role of sentinel lymph node biopsy (SLNB) remain open to debate. It has been shown that the identification rate of SLN in PTC patients is improved using a radiotracer compared to a dye technique. The aim of this systematic review was to evaluate the role of radioguided SLNB (rSLNB) in the treatment of PTC patients.
    Methods: A systematic search was performed in the PubMed and Embase database to identify all original articles regarding the application of rSLNB in PTC patients. The primary outcome was false negative rate (FNR) of the rSLNB; the secondary outcomes were SLN intraoperative identification rate (IIR), site of lymph node metastasis, and persistent disease during follow up.
    Results: Twelve studies were included. Most of PTC patients were T1-T2. The overall SLN IIR, SLN metastatic rate, and FNR were 92.1%, 33.6%, and 25.4%, respectively. Overall, lymph node metastasis were found in the central compartment (23.0%) and in the lateral compartments (10.6%). The persistent disease in patients who underwent SLNB associated to lymph node dissection (LND) in the same compartment of the SLN regardless of the SLN status was 0.6%.
    Conclusions: In all PTC patients, also in T1-T2 stage, due to the high FNR the SLNB performed alone should be abandoned and converted into a technique to guide the lymphadenectomy in a specific neck compartment (i.e., central or lateral) based on the radioactivity, regardless of the SLN status, for better lymph node staging and selection of patients for postoperative radioiodine ablation.
    Language English
    Publishing date 2017-01-18
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 3016969-0
    ISSN 2227-8575 ; 2227-684X
    ISSN (online) 2227-8575
    ISSN 2227-684X
    DOI 10.21037/gs.2016.11.08
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The application of drains in thyroid surgery.

    Portinari, Mattia / Carcoforo, Paolo

    Gland surgery

    2017  Volume 6, Issue 5, Page(s) 563–573

    Abstract: It has been shown that the use of drain in thyroid surgery does not reduce the reoperation rate for hemorrhage. The aim of this systematic review was to update the knowledge of the role of drain in thyroid surgery in term of postoperative complications, ... ...

    Abstract It has been shown that the use of drain in thyroid surgery does not reduce the reoperation rate for hemorrhage. The aim of this systematic review was to update the knowledge of the role of drain in thyroid surgery in term of postoperative complications, pain and hospital length of stay (LOS). A systematic search was performed in the PubMed and Embase database to identify all randomized controlled trials (RCTs) comparing clinical outcomes in patients who underwent thyroidectomy or lobectomy with or without drainage. The primary outcome was reoperation rate for bleeding; the secondary outcomes were development of hematoma, seroma, and wound infection; postoperative pain evaluated by Visual Analogue Scale (VAS) at the postoperative day (POD) 1, and hospital LOS. Risk ratios (RRs) and 95% confident intervals (95% CI) were used for dichotomous variables; mean differences (MDs) and 95% CI for continuous variables. Statistical heterogeneity was evaluated and its degree was quantified by the I2 statistic. Twenty RCTs were included, with 2,204 patients enrolled. No difference was found between the two groups in term of reoperation [RR 1.13 (0.43, 2.95); I2 =0%], hematoma [RR 1.18 (0.71, 1.95); I2 =0%], and seroma [RR 0.82 (0.44, 1.53); I2 =0%]. Patients with drain had higher postoperative pain [MD 1.91 (1.30, 2.53); I2 =97%], prolonged hospital LOS [MD 1.34 (0.91, 1.76) days; I2 =98%], and increased wound infection rate [RR 2.82 (1.36, 5.86); I2 =0%], even though the latter was not confirmed in the sensitivity analysis including only studies with ≥100 patients per trial. The use of drain after thyroid surgery increase postoperative pain and hospital LOS, with no decrease of reoperation rate, hematoma and seroma formation. An increased wound infection rate in patients with drain is suggested, but a large RCT should be performed to confirm this correlation.
    Language English
    Publishing date 2017-01-17
    Publishing country China (Republic : 1949- )
    Document type Journal Article ; Review
    ZDB-ID 3016969-0
    ISSN 2227-8575 ; 2227-684X
    ISSN (online) 2227-8575
    ISSN 2227-684X
    DOI 10.21037/gs.2017.07.04
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  6. Article ; Online: Lymph Node Biopsy in Patients With Papillary Thyroid Cancer.

    Portinari, Mattia / Carcoforo, Paolo

    JAMA otolaryngology-- head & neck surgery

    2017  Volume 143, Issue 4, Page(s) 428–429

    MeSH term(s) Humans ; Lymph Nodes ; Lymphoscintigraphy ; Sentinel Lymph Node Biopsy ; Single Photon Emission Computed Tomography Computed Tomography ; Thyroid Neoplasms/surgery
    Language English
    Publishing date 2017-01-25
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2016.3650
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  7. Article ; Online: Predictive Factors of Recurrence After Laparoscopic Incisional Hernia Repair: A Retrospective Multicentre Cohort Study.

    Soliani, Giorgio / De Troia, Alessandro / Pesce, Antonio / Portinari, Mattia / Fabbri, Nicolò / Leonardi, Luca / Neri, Silvia / Carcoforo, Paolo / Feo, Carlo V

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2023  Volume 33, Issue 5, Page(s) 427–433

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Incisional Hernia/surgery ; Cohort Studies ; Retrospective Studies ; Laparoscopy/methods ; Herniorrhaphy/methods ; Surgical Mesh ; Hernia, Ventral/surgery
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2022.0465
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Non-traumatic emergency abdominal surgery in nonagenarian patients: a retrospective study.

    Portinari, Mattia / Bianchi, Lara / De Troia, Alessandro / Valpiani, Giorgia / Spadaro, Savino / Fogagnolo, Alberto / Acciarri, Pierfilippo / Soliani, Giorgio / Carcoforo, Paolo

    European journal of trauma and emergency surgery : official publication of the European Trauma Society

    2021  Volume 48, Issue 2, Page(s) 1205–1216

    Abstract: Purpose: The primary aim of this study was to evaluate the 30-day survival of nonagenarian patients who underwent non-traumatic emergency abdominal surgery. Other aims were: 90-day and 12-month survival rates, the postoperative complications rate, the ... ...

    Abstract Purpose: The primary aim of this study was to evaluate the 30-day survival of nonagenarian patients who underwent non-traumatic emergency abdominal surgery. Other aims were: 90-day and 12-month survival rates, the postoperative complications rate, the impact of the emergency operation on postoperative functional status, the accuracy of the P-POSSUM in predicting 30-day postoperative mortality and changes in care services after surgery.
    Methods: This was a retrospective cohort study of nonagenarian patients who underwent non-traumatic emergency abdominal surgery between January 2010 and June 2017. Patients were divided in two groups according to the 30-day survival status to compare the distribution of patients' characteristics and postoperative outcomes. Overall survival was estimated using the Kaplan-Meier method. To assess the accuracy of P-POSSUM to predict 30-day mortality, a receiver operating characteristic curve and the Hosmer-Lemeshow goodness of fit test were used.
    Results: 85 nonagenarian patients were enrolled in this study; of these, 27 (31.8%) died within 30 days. The Kaplan-Meier curve showed a rapid decline in survival over the first 30 postoperative days, followed by a more gradual reduction during the rest of the first year. The majority of patients (92.6%) who died within 30 days experienced a medical complication, with a preponderance of respiratory failure (48.2%) and multiple organ failure (33.3%). In the surviving patients, the postoperative functional status had worsened, and 64.2% of patients did not return to their original housing situation or were institutionalized. The accuracy of P-POSSUM in predicting 30-day mortality in nonagenarian patients was poor.
    Conclusions: This study may help doctors convey the postoperative risks of morbidity and mortality, and also to adequately inform relatives about the possible adverse discharge destination of surviving nonagenarian patients with a consequent increase in care needs.
    MeSH term(s) Abdomen ; Aged, 80 and over ; Humans ; Nonagenarians ; Postoperative Complications/epidemiology ; Postoperative Period ; ROC Curve ; Retrospective Studies ; Risk Assessment/methods
    Language English
    Publishing date 2021-03-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2275480-5
    ISSN 1863-9941 ; 1863-9933
    ISSN (online) 1863-9941
    ISSN 1863-9933
    DOI 10.1007/s00068-021-01646-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reply.

    Feo, Carlo / Tsolaki, Elpiniki / Mascoli, Francesco / Portinari, Mattia

    Journal of vascular surgery

    2016  Volume 64, Issue 4, Page(s) 1191–1192

    Language English
    Publishing date 2016-10
    Publishing country United States
    Document type Letter
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2016.05.075
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  10. Article ; Online: Laparoscopic versus open incisional hernia repair: a retrospective cohort study with costs analysis on 269 patients.

    Soliani, G / De Troia, A / Portinari, M / Targa, S / Carcoforo, P / Vasquez, G / Fisichella, P M / Feo, C V

    Hernia : the journal of hernias and abdominal wall surgery

    2017  Volume 21, Issue 4, Page(s) 609–618

    Abstract: Purpose: To compare clinical outcomes and institutional costs of elective laparoscopic and open incisional hernia mesh repairs and to identify independent predictors of prolonged operative time and hospital length of stay (LOS).: Methods: ... ...

    Abstract Purpose: To compare clinical outcomes and institutional costs of elective laparoscopic and open incisional hernia mesh repairs and to identify independent predictors of prolonged operative time and hospital length of stay (LOS).
    Methods: Retrospective observational cohort study on 269 consecutive patients who underwent elective incisional hernia mesh repair, laparoscopic group (N = 94) and open group (N = 175), between May 2004 and July 2014.
    Results: Operative time was shorter in the laparoscopic versus open group (p < 0.0001). Perioperative morbidity and mortality were similar in the two groups. Patients in the laparoscopic group were discharged a median of 2 days earlier (p < 0.0001). At a median follow-up over 50 months, no difference in hernia recurrence was detected between the groups. In laparoscopic group total institutional costs were lower (p = 0.02). At Cox regression analysis adjusted for potential confounders, large wall defect (W3) and higher operative risk (ASA score 3-4) were associated with prolonged operative time, while midline hernia site was associated with increased hospital LOS. Open surgical approach was associated with prolongation of both operative time and LOS.
    Conclusions: Laparoscopic approach may be considered safely to all patients for incisional hernia repair, regardless of patients' characteristics (age, gender, BMI, ASA score, comorbidities) and size of the wall defect (W2-3), with the advantage of shorter operating time and hospital LOS that yields reduced total institutional costs. Patients with higher ASA score and large hernia defects are at risk of prolonged operative time, while an open approach is associated with longer duration of surgical operation and hospital LOS.
    Keywords covid19
    Language English
    Publishing date 2017-08
    Publishing country France
    Document type Journal Article
    ZDB-ID 1388125-5
    ISSN 1248-9204 ; 1265-4906
    ISSN (online) 1248-9204
    ISSN 1265-4906
    DOI 10.1007/s10029-017-1601-3
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