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  1. AU="Pospísil, V"
  2. AU=Driscoll David R AU=Driscoll David R
  3. AU="Wojtalewicz, Nathalie"
  4. AU="Waingrow, Marshall"
  5. AU="Daymé Gonzalez Rodriguez"
  6. AU="Lou, Shuyi"
  7. AU="Figueiredo, Rodrigo S"
  8. AU=Fleet James C
  9. AU="Brohawn, David G"
  10. AU="Cho, Chun-Chieh"
  11. AU="van Raalte, Daniël H"
  12. AU="Zargarian, Loussiné"
  13. AU=Hascalovici Jacob
  14. AU="Spagnolo, Jennifer B"
  15. AU="Anderloni, Giulia"
  16. AU="Ahmad, Shoaib"
  17. AU="Du, Roujia"
  18. AU="Colmenero-Repiso, Ana"
  19. AU="Alvarez-Carbonell, David"
  20. AU="Phelippeau, Michael"
  21. AU="Lunghi, Laura"
  22. AU=Giersiepen Klaus
  23. AU="Drobyshev, Sergey"
  24. AU="Timme, Kathleen H"
  25. AU=Sfriso Paolo
  26. AU="Kim, John S"
  27. AU=Farkash Evan A AU=Farkash Evan A
  28. AU="Xia, Xueqian"

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  1. Artikel: The increase of process stability in removing ammonia nitrogen from wastewater.

    Benáková, Andrea / Johanidesová, Iva / Kelbich, Petr / Pospíšil, Vojtěch / Wanner, Jiří

    Water science and technology : a journal of the International Association on Water Pollution Research

    2018  Band 77, Heft 9-10, Seite(n) 2213–2219

    Abstract: This work focuses on the removal of ammonia nitrogen pollution from wastewaters in a two-stage laboratory model based on a combination of the nitritation and anammox processes with the biomass immobilized in a polyvinyl alcohol (PVA) matrix. Owing to the ...

    Abstract This work focuses on the removal of ammonia nitrogen pollution from wastewaters in a two-stage laboratory model based on a combination of the nitritation and anammox processes with the biomass immobilized in a polyvinyl alcohol (PVA) matrix. Owing to the immobilization approach inside the PVA pellets, the bacterial activity remained nearly unchanged on an abrupt change in the environmental conditions. The nitritation kinetics were significantly dependent on the dissolved oxygen concentration. The critical dissolved oxygen concentration at which the nitritation process using the immobilized bacterial culture stops is 0.6 mg/L. The volumetric rate of nitrogen removal by the anammox bacteria was 158 mg/(L·d). The technology presented is well-suited for removing high ammonia nitrogen concentrations (≥300 mg/L).
    Mesh-Begriff(e) Ammonia/chemistry ; Bacteria/metabolism ; Biomass ; Bioreactors/microbiology ; Nitrogen/chemistry ; Nitrogen/metabolism ; Oxygen ; Waste Disposal, Fluid/methods ; Waste Water/chemistry
    Chemische Substanzen Waste Water ; Ammonia (7664-41-7) ; Nitrogen (N762921K75) ; Oxygen (S88TT14065)
    Sprache Englisch
    Erscheinungsdatum 2018-05-14
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 764273-8
    ISSN 1996-9732 ; 0273-1223
    ISSN (online) 1996-9732
    ISSN 0273-1223
    DOI 10.2166/wst.2018.135
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Circulating microRNAs in Cerebrospinal Fluid and Plasma: Sensitive Tool for Detection of Secondary CNS Involvement, Monitoring of Therapy and Prediction of CNS Relapse in Aggressive B-NHL Lymphomas.

    Krsmanovic, Pavle / Mocikova, Heidi / Chramostova, Kamila / Klanova, Magdalena / Trnkova, Marie / Pesta, Michal / Laslo, Peter / Pytlik, Robert / Stopka, Tomas / Trneny, Marek / Pospisil, Vit

    Cancers

    2022  Band 14, Heft 9

    Abstract: Lymphoma with secondary central nervous system (CNS) involvement represents one of the most aggressive malignancies, with poor prognosis and high mortality. New diagnostic tools for its early detection, response evaluation, and CNS relapse prediction are ...

    Abstract Lymphoma with secondary central nervous system (CNS) involvement represents one of the most aggressive malignancies, with poor prognosis and high mortality. New diagnostic tools for its early detection, response evaluation, and CNS relapse prediction are needed. We analyzed circulating microRNAs in the cerebrospinal fluid (CSF) and plasma of 162 patients with aggressive B-cell non-Hodgkin's lymphomas (B-NHL) and compared their levels in CNS-involving lymphomas versus in systemic lymphomas, at diagnosis and during treatment and CNS relapse. We identified a set of five oncogenic microRNAs (miR-19a, miR-20a, miR-21, miR-92a, and miR-155) in CSF that detect, with high sensitivity, secondary CNS lymphoma involvement in aggressive B-NHL, including DLBCL, MCL, and Burkitt lymphoma. Their combination into an oncomiR index enables the separation of CNS lymphomas from systemic lymphomas or nonmalignant controls with high sensitivity and specificity, and high Receiver Operating Characteristics (DLBCL AUC = 0.96, MCL = 0.93, BL = 1.0). Longitudinal analysis showed that oncomiR levels reflect treatment efficacy and clinical outcomes, allowing their monitoring and prediction. In contrast to conventional methods, CSF oncomiRs enable detection of early and residual CNS involvement, as well as parenchymal involvement. These circulating oncomiRs increase 1-4 months before CNS relapse, allowing its early detection and improving the prediction of CNS relapse risk in DLBCL. Similar effects were detectable, to a lesser extent, in plasma.
    Sprache Englisch
    Erscheinungsdatum 2022-05-06
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14092305
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Differential expression, localization and activity of MARCKS between mantle cell lymphoma and chronic lymphocytic leukemia.

    Vargova, J / Vargova, K / Dusilkova, N / Kulvait, V / Pospisil, V / Zavadil, J / Trneny, M / Klener, P / Stopka, T

    Blood cancer journal

    2016  Band 6, Heft 9, Seite(n) e475

    Sprache Englisch
    Erscheinungsdatum 2016-09-23
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2600560-8
    ISSN 2044-5385 ; 2044-5385
    ISSN (online) 2044-5385
    ISSN 2044-5385
    DOI 10.1038/bcj.2016.80
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Effect of Erythropoietin on the Expression of Murine Transferrin Receptor 2.

    Berezovsky, Betty / Báječný, Martin / Frýdlová, Jana / Gurieva, Iuliia / Rogalsky, Daniel Wayne / Přikryl, Petr / Pospíšil, Vít / Nečas, Emanuel / Vokurka, Martin / Krijt, Jan

    International journal of molecular sciences

    2021  Band 22, Heft 15

    Abstract: Erythropoietin (EPO) downregulates hepcidin expression to increase the availability of iron; the downregulation of hepcidin is mediated by erythroferrone (ERFE) secreted by erythroblasts. Erythroblasts also express transferrin receptor 2 (TFR2); however, ...

    Abstract Erythropoietin (EPO) downregulates hepcidin expression to increase the availability of iron; the downregulation of hepcidin is mediated by erythroferrone (ERFE) secreted by erythroblasts. Erythroblasts also express transferrin receptor 2 (TFR2); however, the possible role of TFR2 in hepcidin downregulation is unclear. The purpose of the study was to correlate liver expression of hepcidin with the expression of ERFE and TFR2 in murine bone marrow and spleen at 4, 16, 24, 48, 72 and 96 h following administration of a single dose of EPO. Splenic
    Mesh-Begriff(e) Animals ; Cells, Cultured ; Cytokines/genetics ; Cytokines/metabolism ; Erythroblasts/drug effects ; Erythroblasts/metabolism ; Erythropoietin/pharmacology ; Exosomes/metabolism ; Hepcidins/genetics ; Hepcidins/metabolism ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Muscle Proteins/genetics ; Muscle Proteins/metabolism ; Receptors, Transferrin/genetics ; Receptors, Transferrin/metabolism ; Spleen/metabolism
    Chemische Substanzen Cytokines ; Erfe protein, mouse ; Hepcidins ; Muscle Proteins ; Receptors, Transferrin ; TFR2 protein, mouse ; Erythropoietin (11096-26-7)
    Sprache Englisch
    Erscheinungsdatum 2021-07-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22158209
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Die Laubmoose Schistostega pennata (Hedw.) Web. & Mohr. Neckera webbiana (Mont.) Dull und Gyroweisia tenuis (Hedw.) Schimp. in der Tschechoslowakei

    Pospisil, V

    Casopis Moravskeho musea. Acta Musei Moraviae - Vedy prirodni. 1983. v.68

    1983  

    Titelübersetzung Mosses Schistostega pennata (Hedw.) Web. & Mohr, Neckera webbiana (Mont.) Dull and Gyroweisia tenuis (hedw.) in Czechoslovakia.
    Schlagwörter Czechoslovakia
    Sprache Deutsch
    Umfang p. 105-129., maps, plates.
    Dokumenttyp Artikel
    Anmerkung Summaries in Czech and English.
    ISSN 0521-2340
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel: Die Laubmoose Mnium spinulosum B.S.G., M. spinosum (Voit) Schwaegr. und M. Hornum Hedw. in der Tschechoslowakei

    Pospisil, V

    Casopis Moravskeho musea. Acta Musei Moraviae - Vedy prirodni. 1981. v. 66

    1981  

    Titelübersetzung Lichens Mnium spinulosum B.S.G., Mnium spinosum (Voit) Schwaegr. and Mnium hornum Hedw. in Czechoslovakia.
    Schlagwörter Czechoslovakia
    Sprache Deutsch
    Umfang p. 51-88., ill., maps, 3 plates.
    Dokumenttyp Artikel
    Anmerkung Summary in Czech.
    ISSN 0521-2340
    Datenquelle NAL Katalog (AGRICOLA)

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  7. Artikel: RNDr. Bohumil Sula--60 let

    Pospisil, V

    Preslia. Aug 1980. v. 52 (3)

    1980  

    Titelübersetzung The 60th birthday of Doctor of Natural Sciences Bohumil Sula.
    Titelvarianten 60th birthday of Doctor of Natural Sciences Bohumil Sula [Botanists, Czechoslovakia]
    Schlagwörter botanists ; Czechoslovakia
    Sprache Tschechisch
    Erscheinungsverlauf 1980-08
    Umfang p. 279-282., ill.
    Dokumenttyp Artikel
    Anmerkung Includes list of his publications.
    ZDB-ID 2128739-9
    ISSN 0032-7786
    ISSN 0032-7786
    Datenquelle NAL Katalog (AGRICOLA)

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  8. Artikel ; Online: Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice.

    Basova, P / Pospisil, V / Savvulidi, F / Burda, P / Vargova, K / Stanek, L / Dluhosova, M / Kuzmova, E / Jonasova, A / Steidl, U / Laslo, P / Stopka, T

    Oncogene

    2014  Band 33, Heft 39, Seite(n) 4735–4745

    Abstract: PU.1 downregulation within hematopoietic stem and progenitor cells (HSPCs) is the primary mechanism for the development of acute myeloid leukemia (AML) in mice with homozygous deletion of the upstream regulatory element (URE) of PU.1 gene. p53 is a well- ... ...

    Abstract PU.1 downregulation within hematopoietic stem and progenitor cells (HSPCs) is the primary mechanism for the development of acute myeloid leukemia (AML) in mice with homozygous deletion of the upstream regulatory element (URE) of PU.1 gene. p53 is a well-known tumor suppressor that is often mutated in human hematologic malignancies including AML and adds to their aggressiveness; however, its genetic deletion does not cause AML in mouse. Deletion of p53 in the PU.1(ure/ure) mice (PU.1(ure/ure)p53(-/-)) results in more aggressive AML with shortened overall survival. PU.1(ure/ure)p53(-/-) progenitors express significantly lower PU.1 levels. In addition to URE deletion we searched for other mechanisms that in the absence of p53 contribute to decreased PU.1 levels in PU.1(ure/ure)p53(-/-) mice. We found involvement of Myb and miR-155 in downregulation of PU.1 in aggressive murine AML. Upon inhibition of either Myb or miR-155 in vitro the AML progenitors restore PU.1 levels and lose leukemic cell growth similarly to PU.1 rescue. The MYB/miR-155/PU.1 axis is a target of p53 and is activated early after p53 loss as indicated by transient p53 knockdown. Furthermore, deregulation of both MYB and miR-155 coupled with PU.1 downregulation was observed in human AML, suggesting that MYB/miR-155/PU.1 mechanism may be involved in the pathogenesis of AML and its aggressiveness characterized by p53 mutation.
    Mesh-Begriff(e) Animals ; Disease Models, Animal ; Gene Expression Regulation, Leukemic ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Liver/pathology ; Mice ; Mice, Knockout ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Oncogene Proteins v-myb/genetics ; Oncogene Proteins v-myb/metabolism ; Promoter Regions, Genetic ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Spleen/pathology ; Trans-Activators/genetics ; Transcriptional Activation ; Tumor Suppressor Protein p53/genetics
    Chemische Substanzen MicroRNAs ; Mirn155 microRNA, mouse ; Myc protein, mouse ; Oncogene Proteins v-myb ; Proto-Oncogene Proteins ; Proto-Oncogene Proteins c-myc ; Trans-Activators ; Tumor Suppressor Protein p53 ; proto-oncogene protein Spi-1
    Sprache Englisch
    Erscheinungsdatum 2014-09-25
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639046-8
    ISSN 1476-5594 ; 0950-9232
    ISSN (online) 1476-5594
    ISSN 0950-9232
    DOI 10.1038/onc.2013.414
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Zum hundertsten Jahrestag der Geburt des Akademikers Josef Podpera

    Pospisil, V

    Casopis Moravskeho musea. = Acta Musei Moraviae. Vedy prirodni. Scientiae naturales. 1979. v. 64

    1979  

    Titelübersetzung The 100th anniversary of Academician Josef Podpera's birthday.
    Titelvarianten 100th anniversary of Academician Josef Podpera's birthday [Botanists, Czechoslovakia]
    Schlagwörter botanists ; Czechoslovakia
    Sprache Deutsch
    Umfang p. 233-234., 2 plates.
    Dokumenttyp Artikel
    ISSN 0521-2340
    Datenquelle NAL Katalog (AGRICOLA)

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  10. Artikel: Laubmoosflora an der mittleren Jihlava

    Pospisil, V

    Casopis Moravskeho musea. = Acta Musei Moraviae. Vedy prirodni. Scientiae naturales. 1979. v. 64

    1979  

    Titelübersetzung Moss flora of the middle reaches of the Jihlava River.
    Schlagwörter Czechoslovakia
    Sprache Deutsch
    Umfang p. 37-64.
    Dokumenttyp Artikel
    Anmerkung Summaries in Czech and English. ; Literature review.
    ISSN 0521-2340
    Datenquelle NAL Katalog (AGRICOLA)

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