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  1. Article ; Online: Disparities in access to COVID-19 vaccine in Verona, Italy: a cohort study using local health immunization data.

    Benoni, Roberto / Sartorello, Anna / Moretti, Francesca / Marchiori, Francesco / Accordini, Luciana / Postiglione, Chiara / Coffele, Viviana / Tardivo, Stefano

    Frontiers in public health

    2023  Volume 11, Page(s) 1167414

    Abstract: Introduction: Migrant populations worldwide were disproportionately impacted by the COVID-19 pandemic. Although substantial resources have been invested in scaling COVID-19 vaccination campaigns, globally vaccine rate and uptake remained low among ... ...

    Abstract Introduction: Migrant populations worldwide were disproportionately impacted by the COVID-19 pandemic. Although substantial resources have been invested in scaling COVID-19 vaccination campaigns, globally vaccine rate and uptake remained low among migrants from across many countries. This study aimed to explore the country of birth as a factor influencing access to the COVID-19 vaccine.
    Methods: This retrospective cohort study included adults vaccinated against SARS-CoV-2 receiving at least one dose in the Verona province between 27 December 2020 and 31 December 2021. Time-to-vaccination was estimated as the difference between the actual date of each person's first dose of COVID-19 vaccination and the date in which the local health authorities opened vaccination reservations for the corresponding age group. The birth country was classified based on both the World Health Organization regions and the World Bank country-level economic classification. Results were reported as the average marginal effect (AME) with corresponding 0.95 confidence intervals (CI).
    Results: During the study period, 7,54,004 first doses were administered and 5,06,734 (F = 2,46,399, 48.6%) were included after applying the exclusion criteria, with a mean age of 51.2 years (SD 19.4). Migrants were 85,989 (17.0%, F = 40,277, 46.8%), with a mean age of 42.4 years (SD 13.3). The mean time-to-vaccination for the whole sample was 46.9 days (SD 45.9), 41.8 days (SD 43.5) in the Italian population, and 71.6 days (SD 49.1) in the migrant one (p < 0.001). The AME of the time-to-vaccination compared to the Italian population was higher by 27.6 [0.95 CI 25.4-29.8], 24.5 [0.95 CI 24.0-24.9], 30.5 [0.95 CI 30.1-31.0] and 7.3 [0.95 CI 6.2-8.3] days for migrants from low-, low-middle-, upper-middle- and high-income countries, respectively. Considering the WHO region, the AME of the time-to-vaccination compared to the Italian group was higher by 31.5 [0.95 CI 30.6-32.5], 31.1 [0.95 CI 30.6-31.5], and 29.2 [0.95 CI 28.5-29.9] days for migrants from African, European, and East-Mediterranean regions, respectively. Overall, time-to-vaccination decreased with increasing age (p < 0.001). Although both migrants and Italians mainly used hub centers (>90%), migrants also used pharmacies and local health units as alternative sites (2.9% and 1.5%, respectively), while Italians (3.3%) and migrants from the European region (4.2%) relied more on family doctors.
    Conclusion: The birth country of migrants influenced access to COVID-19 vaccine both in terms of time-to-vaccination and vaccination points used, especially for the LIC migrant group. Public health authorities should take socio-cultural and economic factors into consideration for tailored communication to people from migrant communities and for planning a mass vaccination campaign.
    MeSH term(s) Adult ; Humans ; Middle Aged ; COVID-19 Vaccines ; Cohort Studies ; Retrospective Studies ; Pandemics/prevention & control ; COVID-19/epidemiology ; COVID-19/prevention & control ; SARS-CoV-2 ; Vaccination ; Italy/epidemiology
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-06-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1167414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Latent Tuberculosis Infection Cascade of Care among Asylum Seekers in Verona, Italy.

    Bordin, Paola / Gazzani, Diana / Postiglione, Chiara / Conti, Emma / Colucci, Laura / Napoletano, Giuseppina / Bosco, Oliviero / Moretti, Francesca / Majori, Silvia

    Journal of health care for the poor and underserved

    2022  Volume 33, Issue 2, Page(s) 934–949

    Abstract: Our study aimed to assess latent tuberculosis infection (LTBI) prevalence, screening uptake, adherence to preventive treatment, and their predictors in a large cohort of asylum seekers. We retrospectively analysed data of migrants screened in 2015-2017 ... ...

    Abstract Our study aimed to assess latent tuberculosis infection (LTBI) prevalence, screening uptake, adherence to preventive treatment, and their predictors in a large cohort of asylum seekers. We retrospectively analysed data of migrants screened in 2015-2017 at the Migrant's Service in Verona, Italy. Sequential interferon-gamma-release-assay (IGRA) was performed to confirm only tuberculin-skin-test (TST) results ranking from 5 to 14 mm. Among 2,486 asylum seekers, screening adherence was 89.74% and LTBI prevalence was 28.8% (CI95% 27.0;30.5). Predictors of LTBI diagnosis were: male gender (OR 1.62), age 24 years or older (OR 1.47) and African origin (OR 1.78). Therapy completion rate was 69.6% and resulted associated with African origin (OR 1.75) and being older than 24 years (OR 2.89). Sequential IGRA testing, given its expensiveness, could be used to confirm only intermediate TST results, thus enabling further LTBI cases to be detected and avoiding unnecessary preventive treatments.
    MeSH term(s) Adult ; Humans ; Interferon-gamma Release Tests/methods ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/epidemiology ; Male ; Mass Screening ; Refugees ; Retrospective Studies ; Tuberculin Test/methods ; Young Adult
    Language English
    Publishing date 2022-05-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1142637-8
    ISSN 1548-6869 ; 1049-2089
    ISSN (online) 1548-6869
    ISSN 1049-2089
    DOI 10.1353/hpu.2022.0073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Extended screening for infectious diseases among newly-arrived asylum seekers from Africa and Asia, Verona province, Italy, April 2014 to June 2015.

    Buonfrate, Dora / Gobbi, Federico / Marchese, Valentina / Postiglione, Chiara / Badona Monteiro, Geraldo / Giorli, Giovanni / Napoletano, Giuseppina / Bisoffi, Zeno

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2018  Volume 23, Issue 16

    Abstract: Background and aimManagement of health issues presented by newly-arrived migrants is often limited to communicable diseases even though other health issues may be more prevalent. We report the results of infectious disease screening proposed to 462 ... ...

    Abstract Background and aimManagement of health issues presented by newly-arrived migrants is often limited to communicable diseases even though other health issues may be more prevalent. We report the results of infectious disease screening proposed to 462 recently-arrived asylum seekers over 14 years of age in Verona province between April 2014 and June 2015.
    MeSH term(s) Adult ; Africa/ethnology ; Asia/ethnology ; Communicable Diseases/diagnosis ; Communicable Diseases/epidemiology ; Female ; HIV Infections/epidemiology ; Hepatitis B/epidemiology ; Humans ; Italy/epidemiology ; Male ; Mass Screening/methods ; Prevalence ; Refugees/statistics & numerical data ; Retrospective Studies ; Syphilis/epidemiology
    Language English
    Publishing date 2018-04-03
    Publishing country Sweden
    Document type Journal Article ; Observational Study
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2018.23.16.17-00527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Epilepsy triggered by mefloquine in an adult traveler to Uganda.

    Gobbi, Federico / Rossanese, Andrea / Buonfrate, Dora / Angheben, Andrea / Postiglione, Chiara / Bisoffi, Zeno

    World journal of clinical cases

    2014  Volume 2, Issue 1, Page(s) 12–15

    Abstract: We report a case of a traveler who visited Uganda for 8 d, and took mefloquine one tablet/week for malaria prophylaxis. After the second dose, he suffered from two episodes of loss of consciousness with seizures, therefore mefloquine was discontinued. ... ...

    Abstract We report a case of a traveler who visited Uganda for 8 d, and took mefloquine one tablet/week for malaria prophylaxis. After the second dose, he suffered from two episodes of loss of consciousness with seizures, therefore mefloquine was discontinued. During the flight back after full recovery, seizures reoccurred while he was on board, he was disembarked in Addis Ababa and then transferred to Nairobi. After repatriation to Italy, he experienced four other similar episodes. The patient was still on full dose anticonvulsant therapy one year and a half after, as any attempt at reduced dose was unsuccessful. Currently, three agents (mefloquine, atovaquone/proguanil, and doxycycline) are recommended for malaria chemoprophylaxis, with similar efficacy but different adverse event profiles, regimens, and prices. Considering that mefloquine is associated with a higher risk of neurologic and psychiatric adverse events than the alternative regimens, we suggest considering mefloquine as a second line choice after atovaquone/proguanil and doxycycline for short-term travelers.
    Language English
    Publishing date 2014-01-27
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v2.i1.12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Imported loiasis in Italy: an analysis of 100 cases.

    Gobbi, Federico / Postiglione, Chiara / Angheben, Andrea / Marocco, Stefania / Monteiro, Geraldo / Buonfrate, Dora / Mascarello, Marta / Gobbo, Maria / Boussinesq, Michel / Bisoffi, Zeno

    Travel medicine and infectious disease

    2014  Volume 12, Issue 6 Pt B, Page(s) 713–717

    Abstract: Background: loiasis is a neglected filariasis, affecting millions of individuals living in the rainforest areas of West and Central Africa. Aim of this study was to compare clinical and parasitological manifestations of loiasis between subjects born in ... ...

    Abstract Background: loiasis is a neglected filariasis, affecting millions of individuals living in the rainforest areas of West and Central Africa. Aim of this study was to compare clinical and parasitological manifestations of loiasis between subjects born in endemic areas and expatriates/travelers.
    Methods: we report clinical and parasitological manifestations of 100 patients with imported loiasis seen between 1993 and 2013 at the Center of Tropical Diseases, Negrar, Italy.
    Results: among the 100 patients, 30 were African immigrants, 70 were Europeans (59 long-term expatriates and 11 travelers). Thirty-five patients (19 Africans and 16 Europeans) had positive microfilaremia. Calabar swellings were twice as frequent in Europeans (90%) than in Africans (46.7%), while a history of "eyeworm" was recorded in a higher proportion of Africans (43.3%) than in Europeans (17.4%). The median duration of exposure in the non-endemic group was also fairly long (14.6 years). Different drug regimens were used for treatment.
    Conclusions: we suggest that the differences between Africans and Europeans are more likely to be related to genetic differences, rather than to chronicity. Moreover the management of imported loiasis needs standardization.
    MeSH term(s) Adult ; African Continental Ancestry Group ; Animals ; Emigrants and Immigrants ; European Continental Ancestry Group ; Female ; Humans ; Italy ; Loiasis/drug therapy ; Loiasis/epidemiology ; Loiasis/ethnology ; Male ; Skin Diseases, Parasitic/epidemiology ; Skin Diseases, Parasitic/ethnology ; Travel
    Language English
    Publishing date 2014-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2014.07.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Coccidioidomycosis: first imported case in Italy.

    Gobbi, Federico / Angheben, Andrea / Farina, Claudio / Buonfrate, Dora / Postiglione, Chiara / Rossanese, Andrea / Anselmi, Mariella / Savio, Chiara / Gobbo, Maria / Bisoffi, Zeno

    Journal of travel medicine

    2012  Volume 19, Issue 3, Page(s) 192–194

    Abstract: We report a case of pulmonary coccidioidomycosis imported from the United States to Italy. This disease should enter in the differential diagnosis of any febrile patient (especially if presenting with pulmonary symptoms, with or without hypereosinophilia) ...

    Abstract We report a case of pulmonary coccidioidomycosis imported from the United States to Italy. This disease should enter in the differential diagnosis of any febrile patient (especially if presenting with pulmonary symptoms, with or without hypereosinophilia) coming from Coccidioides immitis endemic areas.
    MeSH term(s) Adult ; Antifungal Agents/therapeutic use ; Arizona ; Coccidioidomycosis/diagnosis ; Coccidioidomycosis/drug therapy ; Humans ; Italy ; Itraconazole/therapeutic use ; Male ; Travel ; United States
    Chemical Substances Antifungal Agents ; Itraconazole (304NUG5GF4)
    Language English
    Publishing date 2012-05
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1111/j.1708-8305.2012.00599.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Profile of Trypanosoma cruzi infection in a tropical medicine reference center, Northern Italy.

    Gobbi, Federico / Angheben, Andrea / Anselmi, Mariella / Postiglione, Chiara / Repetto, Ernestina / Buonfrate, Dora / Marocco, Stefania / Tais, Stefano / Chiampan, Andrea / Mainardi, Paride / Bisoffi, Zeno

    PLoS neglected tropical diseases

    2014  Volume 8, Issue 12, Page(s) e3361

    Abstract: Background: Chagas disease (CD) is endemic in Central and South America, Mexico and even in some areas of the United States. However, cases have been increasingly recorded also in non-endemic countries. The estimated number of infected people in Europe ... ...

    Abstract Background: Chagas disease (CD) is endemic in Central and South America, Mexico and even in some areas of the United States. However, cases have been increasingly recorded also in non-endemic countries. The estimated number of infected people in Europe is in a wide range of 14000 to 181000 subjects, mostly resident in Spain, Italy and the United Kingdom.
    Methodology/principal findings: Retrospective, observational study describing the characteristics of patients with CD who attended the Centre for Tropical Diseases (Negrar, Verona, Italy) between 2005 and 2013. All the patients affected by CD underwent chest X-ray, ECG, echocardiography, barium X-ray of the oesophagus and colonic enema. They were classified in the indeterminate, cardiac, digestive or mixed category according to the results of the screening tests. Treatment with benznidazole (or nifurtimox in case of intolerance to the first line therapy) was offered to all patients, excluding the ones with advanced cardiomiopathy, pregnant and lactating women. Patients included were 332 (73.9% women). We classified 68.1% of patients as having Indeterminate Chagas, 11.1% Cardiac Chagas, 18.7% as Digestive Chagas and 2.1% as Mixed Form. Three hundred and twenty-one patients (96.7%) were treated with benznidazole, and most of them (83.2%) completed the treatment. At least one adverse effect was reported by 27.7% of patients, but they were mostly mild. Only a couple of patients received nifurtimox as second line treatment.
    Conclusions/significance: Our case series represents the largest cohort of T. cruzi infected patients diagnosed and treated in Italy. An improvement of the access to diagnosis and cure is still needed, considering that about 9200 infected people are estimated to live in Italy. In general, there is an urgent need of common guidelines to better classify and manage patients with CD in non-endemic countries.
    MeSH term(s) Adolescent ; Adult ; Aged ; Chagas Disease/classification ; Chagas Disease/diagnosis ; Chagas Disease/drug therapy ; Chagas Disease/epidemiology ; Child ; Echocardiography ; Electrocardiography ; Female ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Nifurtimox/therapeutic use ; Nitroimidazoles/therapeutic use ; Pregnancy ; Retrospective Studies ; Tropical Medicine ; United States
    Chemical Substances Nitroimidazoles ; Nifurtimox (M84I3K7C2O) ; benzonidazole (YC42NRJ1ZD)
    Language English
    Publishing date 2014-12-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0003361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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