Article ; Online: Acute intermittent porphyria: A rare cause of syndrome of inappropriate antidiuretic hormone secretion.
The journal of the Royal College of Physicians of Edinburgh
2023 Volume 53, Issue 2, Page(s) 111–113
Abstract: A 31-year-old female presented to the emergency department with abdominal pain, vomiting and constipation. Serum sodium levels were recorded at 110 mmol/L on admission, dropping to 96 mmol/L despite fluid restriction. The patient developed hallucinations ...
| Abstract | A 31-year-old female presented to the emergency department with abdominal pain, vomiting and constipation. Serum sodium levels were recorded at 110 mmol/L on admission, dropping to 96 mmol/L despite fluid restriction. The patient developed hallucinations and required hypertonic saline administration in critical care. Urinary sodium was detected at 149 mmol/L, consistent with syndrome of inappropriate antidiuretic hormone secretion (SiADH). Urinary porphyrins were also raised, consistent with a diagnosis of acute intermittent porphyria with SiADH as a complication. |
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| MeSH term(s) | Female ; Humans ; Adult ; Inappropriate ADH Syndrome/diagnosis ; Inappropriate ADH Syndrome/etiology ; Porphyria, Acute Intermittent/complications ; Porphyria, Acute Intermittent/diagnosis ; Abdominal Pain/etiology ; Vasopressins ; Sodium |
| Chemical Substances | Vasopressins (11000-17-2) ; Sodium (9NEZ333N27) |
| Language | English |
| Publishing date | 2023-03-08 |
| Publishing country | England |
| Document type | Case Reports ; Journal Article |
| ZDB-ID | 2866363-9 |
| ISSN | 2042-8189 ; 0953-0932 |
| ISSN (online) | 2042-8189 |
| ISSN | 0953-0932 |
| DOI | 10.1177/14782715231161499 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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