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  1. Article ; Online: Improving DEIB in Addiction Medicine Training Through Interdisciplinary Collaboration and Program Evaluation.

    Ly, Sophia M / Fitzpatrick, Amanda M / Canfield, Jules / Powis, Amaya / So-Armah, Kaku / Hurstak, Emily E

    Substance abuse

    2023  Volume 44, Issue 4, Page(s) 277–281

    Abstract: Developing a diverse Addiction Medicine (AM) workforce will improve medical and public health responses to the increasing health risks created by substance use disorders (SUDs). A workforce that embraces diversity, equity, inclusion, and belonging (DEIB) ...

    Abstract Developing a diverse Addiction Medicine (AM) workforce will improve medical and public health responses to the increasing health risks created by substance use disorders (SUDs). A workforce that embraces diversity, equity, inclusion, and belonging (DEIB) principles may foster novel responses to address the disparities in treatment and outcomes experienced by Black, Indigenous, and People of Color (BIPOC) who are impacted by SUDs. However, experiences of bias and discrimination in the workplace and a lack of exposure to addiction-related content in educational settings limit opportunities to develop and retain a diverse workforce. In this commentary, we describe the creation of the Inclusion, Diversity, and Equity in Addiction medicine, Addiction research, and Addiction health professions (IDEAAA) initiative, a strategy to foster diversity in the field of addiction through efforts targeting learners at different stages of the biomedical education pipeline. Now in its second year, the IDEAAA Program is focused on programmatic evaluation through a qualitative interview study of AM training programs to improve the understanding of experiences of participants who are self-identified members of underrepresented groups (URGs). Interdisciplinary programs with multi-faceted approaches are a strategy to improve DEIB in the AM workforce; IDEAAA's design and methods can inform other AM programs who have the desire to improve DEIB through novel approaches.
    MeSH term(s) Humans ; Program Evaluation ; Addiction Medicine ; Workforce
    Chemical Substances N-(2-(diethylamino)ethyl)-4-iodobenzamide (106790-96-9)
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1458030-5
    ISSN 1547-0164 ; 0889-7077
    ISSN (online) 1547-0164
    ISSN 0889-7077
    DOI 10.1177/08897077231199552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Viruses and Metabolism: The Effects of Viral Infections and Viral Insulins on Host Metabolism.

    Girdhar, Khyati / Powis, Amaya / Raisingani, Amol / Chrudinová, Martina / Huang, Ruixu / Tran, Tu / Sevgi, Kaan / Dogus Dogru, Yusuf / Altindis, Emrah

    Annual review of virology

    2022  Volume 8, Issue 1, Page(s) 373–391

    Abstract: Over the past decades, there have been tremendous efforts to understand the cross-talk between viruses and host metabolism. Several studies have elucidated the mechanisms through which viral infections manipulate metabolic pathways including glucose, ... ...

    Abstract Over the past decades, there have been tremendous efforts to understand the cross-talk between viruses and host metabolism. Several studies have elucidated the mechanisms through which viral infections manipulate metabolic pathways including glucose, fatty acid, protein, and nucleotide metabolism. These pathways are evolutionarily conserved across the tree of life and extremely important for the host's nutrient utilization and energy production. In this review, we focus on host glucose, glutamine, and fatty acid metabolism and highlight the pathways manipulated by the different classes of viruses to increase their replication. We also explore a new system of viral hormones in which viruses mimic host hormones to manipulate the host endocrine system. We discuss viral insulin/IGF-1-like peptides and their potential effects on host metabolism. Together, these pathogenesis mechanisms targeting cellular signaling pathways create a multidimensional network of interactions between host and viral proteins. Defining and better understanding these mechanisms will help us to develop new therapeutic tools to prevent and treat viral infections.
    MeSH term(s) Glycolysis ; Host-Pathogen Interactions ; Humans ; Insulins/pharmacology ; Virus Diseases/drug therapy ; Virus Replication ; Viruses
    Chemical Substances Insulins
    Language English
    Publishing date 2022-02-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2764224-0
    ISSN 2327-0578 ; 2327-056X
    ISSN (online) 2327-0578
    ISSN 2327-056X
    DOI 10.1146/annurev-virology-091919-102416
    Database MEDical Literature Analysis and Retrieval System OnLINE

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