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  1. Article ; Online: Commentary: Ocular lesions in leprosy - Should we forget?

    Biswas, Jyotirmay / Pradhan, Arkaprava

    Indian journal of ophthalmology

    2022  Volume 70, Issue 7, Page(s) 2673–2674

    MeSH term(s) Eye ; Face ; Humans ; Leprosy/complications ; Leprosy/diagnosis
    Language English
    Publishing date 2022-07-05
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_186_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Commentary: SARS-CoV-2 in tears: It really matters.

    Biswas, Jyotirmay / Pradhan, Arkaprava

    Indian journal of ophthalmology

    2021  Volume 69, Issue 12, Page(s) 3636–3637

    MeSH term(s) COVID-19 ; Conjunctiva ; Humans ; SARS-CoV-2 ; Tears
    Language English
    Publishing date 2021-12-15
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_2391_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Leopard retinopathy: An unusual presentation of sympathetic ophthalmia.

    Shah, Mauli / Pradhan, Arkaprava / Dutta Majumder, Parthopratim

    European journal of ophthalmology

    2022  Volume 33, Issue 3, Page(s) NP131–NP135

    Abstract: We report an unusual case of sympathetic ophthalmia (SO) in an elderly gentleman following multiple eye surgeries. He presented with diffuse granulomatous panuveitis resembling leopard retinopathy in the left eye. There was a delay in the initiation of ... ...

    Abstract We report an unusual case of sympathetic ophthalmia (SO) in an elderly gentleman following multiple eye surgeries. He presented with diffuse granulomatous panuveitis resembling leopard retinopathy in the left eye. There was a delay in the initiation of effective treatment of his intraocular inflammation, but he responded to corticosteroid and azathioprine. The pigmentary changes in his fundus were highly unusual, and he was investigated extensively to rule out other possible causes including a search for occult malignancy. The delay in initiation of effective treatment or suboptimal therapy in SO, can lead to variable clinical picture in elderly patients. A proper screening to exclude any malignancy along with aggressive immunosuppressive therapy can achieve optimum results.
    MeSH term(s) Male ; Humans ; Aged ; Ophthalmia, Sympathetic/diagnosis ; Ophthalmia, Sympathetic/drug therapy ; Ophthalmia, Sympathetic/etiology ; Retinal Diseases/diagnosis ; Retinal Diseases/drug therapy ; Retinal Diseases/etiology ; Azathioprine/therapeutic use ; Ophthalmologic Surgical Procedures/adverse effects ; Eye
    Chemical Substances Azathioprine (MRK240IY2L)
    Language English
    Publishing date 2022-03-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721221085851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Polymerase chain reaction: A novel way to detect ocular dirofilariasis.

    Pradhan, Arkaprava / Raman, Muthusamy / Biswas, Jyotirmay

    Indian journal of ophthalmology

    2022  Volume 70, Issue 7, Page(s) 2620–2621

    MeSH term(s) Animals ; Dirofilariasis/diagnosis ; Eye ; Face ; Humans
    Language English
    Publishing date 2022-07-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_2873_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Structural and functional phenotypic features and molecular analysis of Indian patients with Bietti crystalline dystrophy.

    Ratra, Dhanashree / Chattree, Surabhi / Raviselvan, Munispriyan / Pradhan, Arkaprava / Giridhar, Sneha

    Indian journal of ophthalmology

    2022  Volume 70, Issue 7, Page(s) 2526–2532

    Abstract: Purpose: Bietti crystalline dystrophy (BCD) is a rare retinal dystrophy, uncommon in Indians. This study describes the various phenotypic features seen in the Indian population.: Methods: In this retrospective, descriptive case series, records of ... ...

    Abstract Purpose: Bietti crystalline dystrophy (BCD) is a rare retinal dystrophy, uncommon in Indians. This study describes the various phenotypic features seen in the Indian population.
    Methods: In this retrospective, descriptive case series, records of patients with either clinical or molecular diagnosis of BCD from 2009 to 2020 were perused. Phenotypic and genotype information was collected and analyzed.
    Results: This study included 58 patients of BCD (31 males) aged 21-79 years (mean: 47 ± 14 years). The age at onset ranged from 7 to 41 years (mean: 28.8 ± 5.1 years). Vision ranged from 20/20 to counting fingers. There were 18 (31%) patients with stage 1 with crystals and mild retinochoroidal atrophy, 22 (38%) with stage 2 with atrophy extending beyond arcades, and 18 (31%) with absent crystals and extensive atrophy of stage 3. Choroidal neovascular membrane was seen in four patients. The optical coherence tomography showed retinochoroidal thinning (84.6%), outer retinal tubulations (71.8%), and paradoxical foveal thickening with interlaminar bridges (7.7%). Electrophysiology and visual fields showed reduced responses in advanced retinochoroidal changes. Molecular confirmation was available in five patients; five mutations were seen in the CYP4V2.
    Conclusion: A wide variation is seen in the phenotypic picture of BCD. A molecular diagnosis is helpful in differentiating from other retinal dystrophies. The OCT shows the peculiar feature of the interlaminar bridge in early cases with photoreceptor loss. Further investigations into this OCT feature may provide insights into the pathogenesis of BCD. A genotype-phenotype correlation could not be done.
    MeSH term(s) Atrophy ; Corneal Dystrophies, Hereditary/diagnosis ; Corneal Dystrophies, Hereditary/genetics ; Cytochrome P450 Family 4/genetics ; Humans ; Male ; Retinal Diseases ; Retrospective Studies
    Chemical Substances Cytochrome P450 Family 4 (EC 1.14.14.1)
    Language English
    Publishing date 2022-07-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_2146_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lowering of intraocular pressure after phacoemulsification in primary open-angle and angle-closure glaucoma: Correlation with lens thickness.

    Kader, Mohideen Abdul / Pradhan, Arkaprava / Shukla, Aakriti Garg / Maheswari, Devendra / Ramakrishnan, R / Midya, Debahuti

    Indian journal of ophthalmology

    2022  Volume 70, Issue 2, Page(s) 574–579

    Abstract: Purpose: To assess anterior chamber configuration changes during phacoemulsification in primary angle-closure suspect (PACS/PAC) and primary open-angle glaucoma (POAG).: Methods: Prospective observational comparative study of anterior segment optical ...

    Abstract Purpose: To assess anterior chamber configuration changes during phacoemulsification in primary angle-closure suspect (PACS/PAC) and primary open-angle glaucoma (POAG).
    Methods: Prospective observational comparative study of anterior segment optical coherence tomography (AS-OCT) findings before and after phacoemulsification on three groups of patients (PACS/PAC, POAG, and controls). Data were collected over a period of 9 months. Main outcome measures included mean change in anterior chamber depth (ACD), angle opening distance (AOD), and trabecular iris space area (TISA).
    Results: 153 patients (51 PACS/PAC, 51 POAG, and 51 controls) were included in the study. Change in all parameters (ACD, AOD at 500 um, and AOD at 750 um) between the groups demonstrated a greater change in PACS/PAC as compared to POAG and controls. AOD at 750 μm in the temporal quadrant, which has been considered to be having the highest correlation or best representation of the angle, increased in all groups after phacoemulsification (463.59 ± 10.99 vs. 656.27 ± 9.73 mm in PACS; 521.29 ± 16.36 vs. 674.37 ± 8.72 mm in POAG; 549.27 ± 12.40 vs. 702.82 ± 13.04 mm in controls, (P < 0.001). After phacoemulsification, intraocular pressure (IOP) decreased by 2.75 ± 1.17 mm Hg in PACS/PAC (P < 0.001), 2.14 ± 1.33 mm Hg in POAG and 1.90 ± 1.25 mm Hg in controls and it was statistically significant in the PACS group compared to control (P < 0.001).
    Conclusion: Phacoemulsification with intraocular lens implantation is associated with increase in the ACD and angle parameters and a corresponding decrease in IOP. Findings were more pronounced in PACS/PAC suggesting early phacoemulsification may be a treatment option in this group.
    MeSH term(s) Glaucoma, Angle-Closure/diagnosis ; Glaucoma, Angle-Closure/surgery ; Glaucoma, Open-Angle/complications ; Glaucoma, Open-Angle/diagnosis ; Glaucoma, Open-Angle/surgery ; Gonioscopy ; Humans ; Intraocular Pressure ; Phacoemulsification/methods ; Prospective Studies ; Tomography, Optical Coherence/methods
    Language English
    Publishing date 2022-01-27
    Publishing country India
    Document type Journal Article ; Observational Study
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1538_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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