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  1. Article ; Online: Response to: 'Peer observation of student-led teaching'.

    Prakash, Anavi

    Medical teacher

    2023  Volume 46, Issue 1, Page(s) 149

    MeSH term(s) Humans ; Education, Medical, Undergraduate ; Students, Medical ; Peer Group ; Teacher Training ; Teaching
    Language English
    Publishing date 2023-08-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 424426-6
    ISSN 1466-187X ; 0142-159X
    ISSN (online) 1466-187X
    ISSN 0142-159X
    DOI 10.1080/0142159X.2023.2250542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Improvements in Sperm Motility Following Low- or High-Intensity Dietary Interventions in Men With Obesity.

    Sharma, Aditi / Papanikolaou, Nikoleta / Abou Sherif, Sara / Dimakopolou, Anastasia / Thaventhiran, Thilipan / Go, Cara / Holtermann Entwistle, Olivia / Brown, Adrian / Luo, Rong / Jha, Rama / Prakash, Anavi / Khalifa, Dalia / Lewis, Hannah / Ramaraju, Sruthi / Leeds, Anthony R / Chahal, Harvinder / Purkayastha, Sanjay / Henkel, Ralf / Minhas, Sukhbinder /
    Frost, Gary / Dhillo, Waljit S / Jayasena, Channa N

    The Journal of clinical endocrinology and metabolism

    2023  Volume 109, Issue 2, Page(s) 449–460

    Abstract: Introduction: Obesity increases risks of male infertility, but bariatric surgery does not improve semen quality. Recent uncontrolled studies suggest that a low-energy diet (LED) improves semen quality. Further evaluation within a randomized, controlled ... ...

    Abstract Introduction: Obesity increases risks of male infertility, but bariatric surgery does not improve semen quality. Recent uncontrolled studies suggest that a low-energy diet (LED) improves semen quality. Further evaluation within a randomized, controlled setting is warranted.
    Methods: Men with obesity (18-60 years) with normal sperm concentration (normal count) (n = 24) or oligozoospermia (n = 43) were randomized 1:1 to either 800 kcal/day LED for 16 weeks or control, brief dietary intervention (BDI) with 16 weeks' observation. Semen parameters were compared at baseline and 16 weeks.
    Results: Mean age of men with normal count was 39.4 ± 6.4 in BDI and 40.2 ± 9.6 years in the LED group. Mean age of men with oligozoospermia was 39.5 ± 7.5 in BDI and 37.7 ± 6.6 years in the LED group. LED caused more weight loss than BDI in men with normal count (14.4 vs 6.3 kg; P < .001) and men with oligozoospermia (17.6 vs 1.8 kg; P < .001). Compared with baseline, in men with normal count total motility (TM) increased 48 ± 17% to 60 ± 10% (P < .05) after LED, and 52 ± 8% to 61 ± 6% (P < .0001) after BDI; progressive motility (PM) increased 41 ± 16% to 53 ± 10% (P < .05) after LED, and 45 ± 8% to 54 ± 65% (P < .001) after BDI. In men with oligozoospermia compared with baseline, TM increased 35% [26] to 52% [16] (P < .05) after LED, and 43% [28] to 50% [23] (P = .0587) after BDI; PM increased 29% [23] to 46% [18] (P < .05) after LED, and 33% [25] to 44% [25] (P < .05) after BDI. No differences in postintervention TM or PM were observed between LED and BDI groups in men with normal count or oligozoospermia.
    Conclusion: LED or BDI may be sufficient to improve sperm motility in men with obesity. The effects of paternal dietary intervention on fertility outcomes requires investigation.
    MeSH term(s) Male ; Humans ; Semen Analysis ; Sperm Motility ; Oligospermia ; Semen ; Sperm Count ; Infertility, Male/etiology ; Spermatozoa ; Obesity/complications ; Obesity/surgery
    Language English
    Publishing date 2023-09-01
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgad523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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