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  1. Article ; Online: Advanced-Platelet Rich Fibrin Assisted Papilla Reconstruction by Modified Beagle’s Technique- A Novel Approach

    Rajaram Vijayalakshmi / Ravi Sathyapriya / Prakash Prashanthi / Chellathurai Burnice

    Journal of Clinical and Diagnostic Research, Vol 14, Iss 4, Pp ZD07-ZD

    2020  Volume 09

    Abstract: The loss of key papilla in an unaesthetic zone and the presence of a “black triangle” depicts the requirement for papillary reconstruction. The complete reconstruction of lost papilla is unpredictable; therefore, retention of papilla is very important ... ...

    Abstract The loss of key papilla in an unaesthetic zone and the presence of a “black triangle” depicts the requirement for papillary reconstruction. The complete reconstruction of lost papilla is unpredictable; therefore, retention of papilla is very important for aesthetics. There are many causes for loss of papillae and the establishment of “black triangle” between teeth. However, the most common cause is loss of periodontal support due to plaque-associated lesions. However, abnormaility in tooth shape, improper contours of the prosthetic restorations and traumatic oral hygienic procedures may also impact the interdental papilla. The loss of interdental papilla soft tissue causes difficulties in phonetics, aesthetic appearance and lateral food impaction. This case report deals with a variant method of Beagle’s technique 37-year-old systemically healthy male patient with the chief complaint of black space between the upper front teeth region, causing displeasing smile and food entrapment. Intraoral examination done with periodontal probe revealed the loss of 2 mm of interdental papilla. Patient was treated surgically with Advanced Platelet Rich Fibrin (A-PRF) membrane for papilla reconstruction in the upper anterior aesthetic zone.
    Keywords aesthetics ; black triangle ; interdental papilla ; Medicine ; R
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Determination of serum and gingival crevicular fluid levels of omentin in healthy and rheumatoid arthritis subjects with and without periodontitis.

    Mohit, Jyothi / Ari, Geetha / Mahendra, Jaideep / Prakash, Prashanthi / Bedi, Muskan / Dave, Pavithra H / Logaranjani, Anitha / Namasivayam, Ambalavanan

    Oral diseases

    2023  

    Abstract: Objective: The aim of this study was to assess and correlate the serum and GCF levels of omentin with the periodontal status of rheumatoid arthritis (RA) patients with and without periodontitis.: Methods: Forty-four patients were divided into four ... ...

    Abstract Objective: The aim of this study was to assess and correlate the serum and GCF levels of omentin with the periodontal status of rheumatoid arthritis (RA) patients with and without periodontitis.
    Methods: Forty-four patients were divided into four groups: group H: 11 systemically and periodontally healthy subjects; group P: 11 systemically healthy subjects with periodontitis; group RA: 11 periodontally healthy subjects with rheumatoid arthritis and group RA + P: 11 rheumatoid arthritis subjects with periodontitis. Periodontal parameters (plaque index, modified gingival index, probing depth, and clinical attachment level) were recorded and serum and GCF samples were collected for the estimation of omentin using ELISA.
    Results: The mean value of plaque index, modified gingival index, probing depth, and clinical attachment level were significantly higher whereas serum and GCF omentin levels were found to be decreased in group IV when compared to the other groups. The significant correlation was found between the serum and GCF omentin levels with all the periodontal parameters.
    Conclusion: The omentin level in serum and GCF was found to be lower in RA patients with periodontitis. It is also inversely correlated with the periodontal parameters. Thus, omentin can serve as a significant diagnostic and therapeutic tool in both periodontal and rheumatoid disease.
    Language English
    Publishing date 2023-07-27
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Calprotectin and periostin levels in periodontitis patients with coronary artery disease.

    Mahendra, Jaideep / Muralidharan, Janani / Srinivasan, Sruthi / Mahendra, Little / Cherian, Sanjay M / Fathima, Lubna / Prakash, Prashanthi / Namasivayam, Ambalavanan / Dave, Pavithra H / Bedi, Muskan / Muralidharan, Harini

    Oral diseases

    2023  

    Abstract: Objective: The aim of the study was to assess the effect of non-surgical periodontal therapy (NSPT) on periodontal and cardiac parameters as well as on the expression of calprotectin and periostin levels in periodontitis patients with and without ... ...

    Abstract Objective: The aim of the study was to assess the effect of non-surgical periodontal therapy (NSPT) on periodontal and cardiac parameters as well as on the expression of calprotectin and periostin levels in periodontitis patients with and without coronary artery disease (CAD).
    Methods: Ninety subjects were categorised into three groups: Group H: periodontally and systemically healthy subjects, Group P: stage III grade B periodontitis subjects with no associated systemic diseases and Group P + CAD: stage III grade B periodontitis subjects diagnosed with CAD. Demographic, periodontal and cardiac parameters were recorded at baseline (0 day) and on the 180th day after NSPT. Gingival crevicular fluid was collected from all participants at baseline (0 day) and after the 180th day. Calprotectin and periostin expression were reassessed.
    Results: A significant increase in the levels of calprotectin (34.05 ± 11.72) was seen at baseline in the P + CAD group, whereas on the contrary, a decreased periostin (1.59 ± 0.41) was also noted at baseline. The study also showed a significant improvement in periodontal and cardiac parameters on the 180th day following NSPT.
    Conclusion: Detection of calprotectin and periostin expression in GCF samples could represent a link to the association of periodontitis and CAD.
    Language English
    Publishing date 2023-07-27
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: miRNA-146a and miRNA-126 as Potential Biomarkers in Patients with Coronary Artery Disease and Generalized Periodontitis.

    Mahendra, Jaideep / Mahendra, Little / Fageeh, Hytham N / Fageeh, Hammam Ibrahim / Ibraheem, Wael / Abdulkarim, Hesham H / Kanakamedala, Anilkumar / Prakash, Prashanthi / Srinivasan, Sruthi / Balaji, Thodur Madapusi / Varadarajan, Saranya / Jagannathan, Raghunathan / Patil, Shankargouda

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 16

    Abstract: The present study aims to compare the levels of micro-RNA-146a and micro-RNA-126 in oral subgingival plaque and coronary plaque from artery walls in patients with coronary artery disease who suffer from generalized periodontitis. A total of 75 ... ...

    Abstract The present study aims to compare the levels of micro-RNA-146a and micro-RNA-126 in oral subgingival plaque and coronary plaque from artery walls in patients with coronary artery disease who suffer from generalized periodontitis. A total of 75 participants were selected and grouped into three categories of 25 patients each: GP+CAD, GP, and HP groups. GP+CAD consisted of patients diagnosed with generalized periodontitis (GP) and coronary artery disease (CAD). The GP+CAD group was further divided into two groups-GP+CADa: where subgingival plaque samples were collected; GP+CADb group: where coronary plaque samples were collected while the patient underwent a coronary artery bypass grafting surgery. The GP group consisted of 25 patients diagnosed with only generalized periodontitis. The HP group consisted of 25 systemically and periodontally healthy controls. miRNA-146a and miRNA126 levels were assessed in subgingival plaque (SP) samples from all groups. Results revealed that miRNA-146a was expressed at higher levels and miRNA-126 was downregulated in the GP+CAD group. microRNAs in subgingival plaque samples showed a significant correlation with the coronary plaque samples in the GP+CAD group. miRNA-146a and miRNA-126 were present in coronary artery disease patients with periodontitis. These micro-RNAs may serve as risk biomarkers for coronary artery disease and generalized periodontitis.
    Language English
    Publishing date 2021-08-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14164692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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