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  1. Book ; Online ; Thesis: Evaluierung der Radiopharmaka-Herstellung in der GMP-Radiopharmazie am Universitätsklinikum Erlangen

    Morgenroth, Benedikt [Verfasser] / Prante, Olaf [Akademischer Betreuer] / Prante, Olaf [Gutachter]

    2022  

    Author's details Benedikt Morgenroth ; Gutachter: Olaf Prante ; Betreuer: Olaf Prante
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
    Publishing place Erlangen
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Book: Angiogenese-Targeting für Diagnose und Therapie - MoBiMed; Teilvorhaben 2 (Uni Erlangen)

    Prante, Olaf

    Berichtszeitraum: 01.09.2008 - 31.08.2012 ; Schlussbericht = Mechanism of targeting-angiogenesis for diagnostics and the therapy, subproject 2 (Uni Erlangen)

    2013  

    Institution Universität Erlangen-Nürnberg
    Author's details Auftragnehmer/Zuwendungsempfänger: FAU Erlangen-Nürnberg. Leiter des Vorhabens: Olaf Prante
    Language German
    Size 16 Bl., Ill.
    Publishing place Erlangen
    Document type Book
    Note Förderkennzeichen BMBF 13EZ0808 [neu] - 01EZ0808 [alt]. - Verbund-Nr. 01067554 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Book ; Online: Angiogenese-Targeting für Diagnose und Therapie - MoBiMed; Teilvorhaben 2 (Uni Erlangen)

    Prante, Olaf

    Berichtszeitraum: 01.09.2008 - 31.08.2012 ; Schlussbericht = Mechanism of targeting-angiogenesis for diagnostics and the therapy, subproject 2 (Uni Erlangen)

    2013  

    Institution Universität Erlangen-Nürnberg
    Author's details Auftragnehmer/Zuwendungsempfänger: FAU Erlangen-Nürnberg. Leiter des Vorhabens: Olaf Prante
    Language German
    Size Online-Ressource (16 S., 97,3 KB), Ill.
    Publisher Technische Informationsbibliothek u. Universitätsbibliothek
    Publishing place Hannover ; Erlangen
    Document type Book ; Online
    Note Förderkennzeichen BMBF 13EZ0808 [neu] - 01EZ0808 [alt]. - Verbund-Nr. 01067554 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Article: Sweetening Pharmaceutical Radiochemistry by

    Shinde, Sandip S / Maschauer, Simone / Prante, Olaf

    Pharmaceuticals (Basel, Switzerland)

    2021  Volume 14, Issue 11

    Abstract: In the field ... ...

    Abstract In the field of
    Language English
    Publishing date 2021-11-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph14111175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: FAPI PET Opens a New Window to Understanding Immune-Mediated Inflammatory Diseases.

    Kuwert, Torsten / Schmidkonz, Christian / Prante, Olaf / Schett, Georg / Ramming, Andreas

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2022  Volume 63, Issue 8, Page(s) 1136–1137

    MeSH term(s) Fluorodeoxyglucose F18 ; Gallium Radioisotopes ; Gelatinases ; Positron Emission Tomography Computed Tomography ; Positron-Emission Tomography ; Quinolines
    Chemical Substances Gallium Radioisotopes ; Quinolines ; Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Gelatinases (EC 3.4.24.-)
    Language English
    Publishing date 2022-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.122.263922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Radiopharmaceuticals for imaging and endoradiotherapy of neurotensin receptor-positive tumors.

    Maschauer, Simone / Prante, Olaf

    Journal of labelled compounds & radiopharmaceuticals

    2018  Volume 61, Issue 3, Page(s) 309–325

    Abstract: The neurotensin receptors are overexpressed in various tumor types, especially in highly progressive pancreatic tumors. As this cancer has a poor 5-year survival prognosis, there is an urgent need to improve early diagnosis and treatment strategies. This ...

    Abstract The neurotensin receptors are overexpressed in various tumor types, especially in highly progressive pancreatic tumors. As this cancer has a poor 5-year survival prognosis, there is an urgent need to improve early diagnosis and treatment strategies. This review article provides an overview of the latest developments in radiopharmaceuticals for neurotensin receptor-positive tumors, including peptidic and non-peptidic radiopharmaceuticals, not only for SPECT and PET but also for endoradiotherapy.
    MeSH term(s) Animals ; Humans ; Neurotensin/analogs & derivatives ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/radiotherapy ; Positron-Emission Tomography/methods ; Radiopharmaceuticals/chemistry ; Radiopharmaceuticals/pharmacology ; Radiopharmaceuticals/therapeutic use ; Radiotherapy/methods ; Receptors, Neurotensin/metabolism
    Chemical Substances Radiopharmaceuticals ; Receptors, Neurotensin ; Neurotensin (39379-15-2)
    Language English
    Publishing date 2018-01-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 196095-7
    ISSN 1099-1344 ; 0362-4803 ; 0022-2135
    ISSN (online) 1099-1344
    ISSN 0362-4803 ; 0022-2135
    DOI 10.1002/jlcr.3581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: 18

    Shinde, Sandip S / Bolik, Kim-Viktoria / Maschauer, Simone / Prante, Olaf

    Pharmaceuticals (Basel, Switzerland)

    2021  Volume 14, Issue 9

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2021-08-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph14090833
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Neurotensin analogs by fluoroglycosylation at N

    Schindler, Lisa / Wohlfahrt, Katrin / Gluhacevic von Krüchten, Lara / Prante, Olaf / Keller, Max / Maschauer, Simone

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 15028

    Abstract: Since neurotensin (NT) receptors of subtype-1 (NTS1) are expressed by different types of malignant tumors, such as pancreatic adenocarcinoma, colorectal and prostate carcinoma, they represent an interesting target for tumor imaging by positron emission ... ...

    Abstract Since neurotensin (NT) receptors of subtype-1 (NTS1) are expressed by different types of malignant tumors, such as pancreatic adenocarcinoma, colorectal and prostate carcinoma, they represent an interesting target for tumor imaging by positron emission tomography (PET) and endoradiotherapy. Previously reported neurotensin-derived NTS1 ligands for PET were radiolabeled by modification and prelongation of the N-terminus of NT(8-13) peptide analogs. In this study, we demonstrate that modifying Arg
    MeSH term(s) Adenocarcinoma/metabolism ; Animals ; Arginine ; Humans ; Male ; Mice ; Neurotensin/metabolism ; Pancreatic Neoplasms ; Positron-Emission Tomography/methods ; Receptors, Neurotensin/metabolism ; Tomography, X-Ray Computed
    Chemical Substances Receptors, Neurotensin ; Neurotensin (39379-15-2) ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 2022-09-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-19296-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Bioconjugation of a Fibroblast Activation Protein Targeted Interleukin-4.

    Ruopp, Matthias / Zhu, Sha / Worschech, Rafael / Haas, Dorothee / Maschauer, Simone / Prante, Olaf / Meinel, Lorenz / Lühmann, Tessa

    ACS biomaterials science & engineering

    2023  Volume 9, Issue 10, Page(s) 5580–5588

    Abstract: Interleukin-4 (IL-4) is an immune-modulating therapeutic with growing potential for the treatment of inflammatory diseases. Current challenges of IL-4 therapy include a low serum half-life and pleiotropic activity, suggesting effective targeting of IL-4. ...

    Abstract Interleukin-4 (IL-4) is an immune-modulating therapeutic with growing potential for the treatment of inflammatory diseases. Current challenges of IL-4 therapy include a low serum half-life and pleiotropic activity, suggesting effective targeting of IL-4. To develop an interleukin-4 bioconjugate with rapid targeting to inflammatory disease sites, we report the chemical synthesis, bioconjugation, and
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Journal Article
    ISSN 2373-9878
    ISSN (online) 2373-9878
    DOI 10.1021/acsbiomaterials.3c00879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Development of

    Potemkin, Roman / Strauch, Brigitte / Kuwert, Torsten / Prante, Olaf / Maschauer, Simone

    Molecular pharmaceutics

    2020  Volume 17, Issue 3, Page(s) 933–943

    Abstract: The prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein that is highly expressed in the malignant human prostate epithelium. Therefore, PSMA has emerged as a very attractive target for developing radiopharmaceuticals for the ...

    Abstract The prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein that is highly expressed in the malignant human prostate epithelium. Therefore, PSMA has emerged as a very attractive target for developing radiopharmaceuticals for the diagnosis, e.g., by positron emission tomography (PET) imaging, and radiotherapy of prostate cancer. The aim of this study was to develop
    MeSH term(s) Animals ; Antigens, Surface/metabolism ; Click Chemistry/methods ; Disease Models, Animal ; Female ; Fluorine Radioisotopes/chemistry ; Glutamate Carboxypeptidase II/antagonists & inhibitors ; Glutamate Carboxypeptidase II/metabolism ; Heterografts ; Humans ; Kidney/drug effects ; Kidney/metabolism ; Ligands ; Liver/drug effects ; Liver/metabolism ; Male ; Mice ; Mice, Nude ; PC-3 Cells ; Positron-Emission Tomography ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/metabolism ; Protease Inhibitors/chemistry ; Protease Inhibitors/pharmacokinetics ; Radiopharmaceuticals/chemistry ; Radiopharmaceuticals/pharmacokinetics ; Tissue Distribution
    Chemical Substances Antigens, Surface ; Fluorine Radioisotopes ; Ligands ; Protease Inhibitors ; Radiopharmaceuticals ; FOLH1 protein, human (EC 3.4.17.21) ; Glutamate Carboxypeptidase II (EC 3.4.17.21) ; Fluorine-18 (GZ5I74KB8G)
    Language English
    Publishing date 2020-02-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2138405-8
    ISSN 1543-8392 ; 1543-8384
    ISSN (online) 1543-8392
    ISSN 1543-8384
    DOI 10.1021/acs.molpharmaceut.9b01179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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